PL3442974T3 - Pochodne pirazolopirymidyny - Google Patents
Pochodne pirazolopirymidynyInfo
- Publication number
- PL3442974T3 PL3442974T3 PL17715204.8T PL17715204T PL3442974T3 PL 3442974 T3 PL3442974 T3 PL 3442974T3 PL 17715204 T PL17715204 T PL 17715204T PL 3442974 T3 PL3442974 T3 PL 3442974T3
- Authority
- PL
- Poland
- Prior art keywords
- pyrazolopyrimidine derivatives
- pyrazolopyrimidine
- derivatives
- Prior art date
Links
- OGEBRHQLRGFBNV-RZDIXWSQSA-N chembl2036808 Chemical class C12=NC(NCCCC)=NC=C2C(C=2C=CC(F)=CC=2)=NN1C[C@H]1CC[C@H](N)CC1 OGEBRHQLRGFBNV-RZDIXWSQSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16165572 | 2016-04-15 | ||
| PCT/EP2017/058519 WO2017178416A1 (en) | 2016-04-15 | 2017-04-10 | Pyrazolopyrimidine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3442974T3 true PL3442974T3 (pl) | 2023-12-04 |
Family
ID=55755480
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL17715204.8T PL3442974T3 (pl) | 2016-04-15 | 2017-04-10 | Pochodne pirazolopirymidyny |
Country Status (22)
| Country | Link |
|---|---|
| US (3) | US10604525B2 (pl) |
| EP (1) | EP3442974B8 (pl) |
| JP (1) | JP7051703B2 (pl) |
| KR (1) | KR102467347B1 (pl) |
| CN (1) | CN109071545B (pl) |
| AR (1) | AR108130A1 (pl) |
| AU (1) | AU2017251155B2 (pl) |
| CA (1) | CA3020793C (pl) |
| CL (1) | CL2018002920A1 (pl) |
| CO (1) | CO2018010966A2 (pl) |
| DO (1) | DOP2018000226A (pl) |
| ES (1) | ES2953467T3 (pl) |
| IL (1) | IL261885A (pl) |
| MX (1) | MX389697B (pl) |
| PH (1) | PH12018550173A1 (pl) |
| PL (1) | PL3442974T3 (pl) |
| RU (1) | RU2769448C2 (pl) |
| SG (1) | SG11201808214TA (pl) |
| TW (1) | TWI742067B (pl) |
| UY (1) | UY37201A (pl) |
| WO (1) | WO2017178416A1 (pl) |
| ZA (1) | ZA201807656B (pl) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20170232024A1 (en) | 2014-08-04 | 2017-08-17 | Jerry Tan Eye Surgery Pte Ltd | Pharmaceutical compositions for demodex related blepharitis and eyelid crusting |
| PL3442974T3 (pl) * | 2016-04-15 | 2023-12-04 | Elanco Animal Health Gmbh | Pochodne pirazolopirymidyny |
| PT3442972T (pt) | 2016-04-15 | 2020-05-29 | Abbvie Inc | Inibidores de bromodomínio |
| US11672800B2 (en) | 2017-04-21 | 2023-06-13 | Epizyme, Inc. | Combination therapies with EHMT2 inhibitors |
| CN110536892B (zh) * | 2017-04-27 | 2023-05-12 | 拜耳动物保健有限责任公司 | 新的二环吡唑衍生物 |
| US10738056B2 (en) | 2017-09-15 | 2020-08-11 | Aduro Biotech Inc. | Pyrazolopyrimidinone compounds and uses thereof |
| IL307992B2 (en) | 2017-12-15 | 2025-03-01 | Tarsus Pharmaceuticals Inc | Parasiticide formulations containing isoxazoline and methods for treating blepharitis |
| DK3790874T3 (da) * | 2018-05-09 | 2023-05-15 | Bayer Animal Health Gmbh | Anthelmintiske kinolinderivater |
| US12269822B2 (en) * | 2018-07-09 | 2025-04-08 | Boehringer Ingelheim Animal Health USA Inc. | Anthelminthic heterocyclic compounds |
| EP3643711A1 (en) * | 2018-10-24 | 2020-04-29 | Bayer Animal Health GmbH | New anthelmintic compounds |
| AR116908A1 (es) * | 2018-12-18 | 2021-06-23 | Elanco Tiergesundheit Ag | Derivados bicíclicos |
| CN113474044A (zh) * | 2018-12-18 | 2021-10-01 | 瑞士伊兰科动物保健有限公司 | 双环衍生物 |
| CN119285648A (zh) * | 2019-03-19 | 2025-01-10 | 勃林格殷格翰动物保健有限公司 | 驱虫的氮杂-苯并噻吩和氮杂-苯并呋喃化合物 |
| US12502377B2 (en) | 2019-04-04 | 2025-12-23 | Tarsus Pharmaceuticals, Inc. | Method of eradicating ticks that attach to humans using lotilaner formulations |
| EP3980414A1 (en) * | 2019-06-07 | 2022-04-13 | Elanco Tiergesundheit AG | Bicyclic derivatives for treating endoparasites |
| TWI865563B (zh) | 2019-07-30 | 2024-12-11 | 德商拜耳動物保健有限公司 | 新穎異喹啉衍生物 |
| MX2022007670A (es) | 2019-12-18 | 2022-07-19 | Intervet Int Bv | Compuestos antihelminticos que comprenden una estructura de quinolina. |
| BR112022012130A2 (pt) | 2019-12-18 | 2022-08-30 | Intervet Int Bv | Compostos antelmínticos compreendendo uma estrutura azaindólica |
| PH12022553222A1 (en) | 2020-05-29 | 2024-02-12 | Boehringer Ingelheim Animal Health Usa Inc | Anthelmintic heterocyclic compounds |
| JP2023553269A (ja) | 2020-11-18 | 2023-12-21 | エランコ・ティアゲゾンタイト・アーゲー | イヌ糸状虫感染症を治療するためのｎ－（２，３－ジヒドロ－１，４－ベンゾオキサジン－４－イル）－３－イソプロピル－７－（２，３，５－トリフルオロフェニル）ベンゾ－チオフェン－２－カルボキサミド誘導体及び類似化合物 |
| CN116685584A (zh) * | 2020-11-18 | 2023-09-01 | 礼蓝动物保健有限公司 | 用于治疗心丝虫感染的n-(2,3-二氢-1,4-苯并噁嗪-4-基)-3-异丙基-7-(2,3,5-三氟苯基)苯并噻吩-2-甲酰胺衍生物和类似化合物 |
| TW202237600A (zh) | 2020-12-04 | 2022-10-01 | 瑞士商禮藍動物保健股份有限公司 | 雙環衍生物 |
| MX2023006744A (es) | 2020-12-11 | 2023-06-19 | Intervet Int Bv | Compuestos antihelminticos que comprenden una estructura de tienopiridina. |
| CN113252824B (zh) * | 2021-06-17 | 2022-04-19 | 湖南农业大学 | 测定水体中三氟苯嘧啶含量的气相色谱-电子捕获检测器法 |
| KR102660894B1 (ko) * | 2021-09-17 | 2024-04-26 | 기초과학연구원 | 피리미딘-2-아민 화합물의 제조방법 |
| MX2024005264A (es) | 2021-11-01 | 2024-05-14 | Boehringer Ingelheim Vetmedica Gmbh | Compuestos de pirrolopiridazina como antihelminticos. |
| WO2024213752A1 (en) | 2023-04-14 | 2024-10-17 | Elanco Animal Health Gmbh | Long-term prevention and/or treatment of a disease by slo-1 inhibitors |
| WO2025027117A1 (en) | 2023-08-02 | 2025-02-06 | Intervet International B.V. | Carboxamide-4-quinoline compounds with anthelmintic activity |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY125533A (en) | 1999-12-06 | 2006-08-30 | Bristol Myers Squibb Co | Heterocyclic dihydropyrimidine compounds |
| RU15525U1 (ru) | 2000-07-04 | 2000-10-20 | Федеральный научно-производственный центр закрытое акционерное общество "Научно-производственный концерн (объединение) "ЭНЕРГИЯ" | Электродвигатель постоянного тока |
| KR20040097375A (ko) * | 2002-04-23 | 2004-11-17 | 시오노기 앤드 컴파니, 리미티드 | 피라졸로[1, 5-에이]피리미딘 유도체 및 이를 함유한엔에이디(피)에이취 산화효소 저해제 |
| GB0213715D0 (en) | 2002-06-14 | 2002-07-24 | Syngenta Ltd | Chemical compounds |
| TWI312272B (en) | 2003-05-12 | 2009-07-21 | Sumitomo Chemical Co | Pyrimidine compound and pests controlling composition containing the same |
| EA009517B1 (ru) * | 2003-06-27 | 2008-02-28 | Байер Кропсайенс Аг | Пиразолопиримидины |
| JP2007506665A (ja) | 2003-06-27 | 2007-03-22 | バイエル・クロツプサイエンス・アクチエンゲゼルシヤフト | ピラゾロピリミジン |
| GB0414438D0 (en) | 2004-06-28 | 2004-07-28 | Syngenta Participations Ag | Chemical compounds |
| RU2394819C2 (ru) | 2004-10-20 | 2010-07-20 | Кумиай Кемикал Индастри Ко., Лтд. | Инсектицид, акарицид и нематоцид, содержащие в качестве активного компонента производное 3-триазолилфенилсульфида |
| BRPI0616839A2 (pt) | 2005-10-06 | 2013-01-01 | Nippon Soda Co | agentes para controle de praga, e, compostos de amina cìclicos |
| EP1918291A1 (en) * | 2006-10-30 | 2008-05-07 | Novartis AG | 3-Aminocarbonyl-substituted fused pyrazolo-derivatives as protein kinase modulators |
| WO2008063671A2 (en) * | 2006-11-20 | 2008-05-29 | Alantos Pharmaceuticals Holding, Inc. | Heterobicyclic metalloprotease inhibitors |
| CN101878217B (zh) | 2007-09-28 | 2014-01-15 | 协和发酵麒麟株式会社 | 皮肤疾病的预防和/或治疗剂 |
| JP5268461B2 (ja) | 2008-07-14 | 2013-08-21 | Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 | Ｐｆ１３６４物質、その製造方法、生産菌株、及び、それを有効成分とする農園芸用殺虫剤 |
| CN101337940B (zh) | 2008-08-12 | 2012-05-02 | 国家农药创制工程技术研究中心 | 具杀虫活性的含氮杂环二氯烯丙醚类化合物 |
| CN101337937B (zh) | 2008-08-12 | 2010-12-22 | 国家农药创制工程技术研究中心 | 具有杀虫活性的n-苯基-5-取代氨基吡唑类化合物 |
| CN101715774A (zh) | 2008-10-09 | 2010-06-02 | 浙江化工科技集团有限公司 | 一个具有杀虫活性化合物制备及用途 |
| EP2184273A1 (de) | 2008-11-05 | 2010-05-12 | Bayer CropScience AG | Halogen-substituierte Verbindungen als Pestizide |
| GB0820344D0 (en) | 2008-11-06 | 2008-12-17 | Syngenta Ltd | Herbicidal compositions |
| US8007468B2 (en) | 2009-07-13 | 2011-08-30 | Navilyst Medical, Inc. | Method to secure an elastic component in a valve |
| WO2011085575A1 (zh) | 2010-01-15 | 2011-07-21 | 江苏省农药研究所股份有限公司 | 邻杂环甲酰苯胺类化合物及其合成方法和应用 |
| MA34551B1 (fr) | 2010-08-31 | 2013-09-02 | Meiji Seika Pharma Co Ltd | Agent de lutte contre des organismes nuisibles |
| CN101967139B (zh) | 2010-09-14 | 2013-06-05 | 中化蓝天集团有限公司 | 一种含一氟甲氧基吡唑的邻甲酰氨基苯甲酰胺类化合物、其合成方法及应用 |
| US8791162B2 (en) | 2011-02-14 | 2014-07-29 | Merck Sharp & Dohme Corp. | Cathepsin cysteine protease inhibitors |
| WO2013050317A1 (en) | 2011-10-03 | 2013-04-11 | Syngenta Limited | Polymorphs of an isoxazoline derivative |
| CN102391261A (zh) | 2011-10-14 | 2012-03-28 | 上海交通大学 | 一种n-取代噁二嗪类化合物及其制备方法和应用 |
| JP2015512907A (ja) | 2012-03-30 | 2015-04-30 | ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ | 有害動物を駆除するためのｎ−置換ピリジニリデン化合物および誘導体 |
| EP2647626A1 (en) | 2012-04-03 | 2013-10-09 | Syngenta Participations AG. | 1-Aza-spiro[4.5]dec-3-ene and 1,8-diaza-spiro[4.5]dec-3-ene derivatives as pesticides |
| MA37572B1 (fr) | 2012-04-27 | 2017-10-31 | Dow Agrosciences Llc | Compositions pesticides et procédés correspondants |
| US9282739B2 (en) | 2012-04-27 | 2016-03-15 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
| US9284310B2 (en) | 2012-11-03 | 2016-03-15 | Boehringer Ingelheim International Gmbh | Inhibitors of cytomegalovirus |
| CN103232431B (zh) | 2013-01-25 | 2014-11-05 | 青岛科技大学 | 一种二卤代吡唑酰胺类化合物及其应用 |
| CN103109816B (zh) | 2013-01-25 | 2014-09-10 | 青岛科技大学 | 硫代苯甲酰胺类化合物及其应用 |
| WO2014158644A1 (en) | 2013-03-13 | 2014-10-02 | Dow Agrosciences Llc | Process for the preparation of triaryl rhamnose carbamates |
| CN103265527B (zh) | 2013-06-07 | 2014-08-13 | 江苏省农用激素工程技术研究中心有限公司 | 邻氨基苯甲酰胺化合物及其制备方法和应用 |
| CN103524422B (zh) | 2013-10-11 | 2015-05-27 | 中国农业科学院植物保护研究所 | 苯并咪唑衍生物及其制备方法和用途 |
| WO2015058028A1 (en) | 2013-10-17 | 2015-04-23 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
| MX2016004943A (es) | 2013-10-17 | 2016-06-28 | Dow Agrosciences Llc | Procesos para la preparacion de compuestos plaguicidas. |
| UY36196A (es) | 2014-07-25 | 2016-02-29 | Bayer Animal Health Gmbh | Compuestos para usar en el tratamiento antihelmíntico |
| PL3442974T3 (pl) | 2016-04-15 | 2023-12-04 | Elanco Animal Health Gmbh | Pochodne pirazolopirymidyny |
-
2017
- 2017-04-10 PL PL17715204.8T patent/PL3442974T3/pl unknown
- 2017-04-10 MX MX2018012544A patent/MX389697B/es unknown
- 2017-04-10 CA CA3020793A patent/CA3020793C/en active Active
- 2017-04-10 WO PCT/EP2017/058519 patent/WO2017178416A1/en not_active Ceased
- 2017-04-10 KR KR1020187032684A patent/KR102467347B1/ko active Active
- 2017-04-10 ES ES17715204T patent/ES2953467T3/es active Active
- 2017-04-10 US US16/093,565 patent/US10604525B2/en active Active
- 2017-04-10 JP JP2018553486A patent/JP7051703B2/ja active Active
- 2017-04-10 RU RU2018140092A patent/RU2769448C2/ru active
- 2017-04-10 CN CN201780023855.8A patent/CN109071545B/zh active Active
- 2017-04-10 EP EP17715204.8A patent/EP3442974B8/en active Active
- 2017-04-10 SG SG11201808214TA patent/SG11201808214TA/en unknown
- 2017-04-10 AU AU2017251155A patent/AU2017251155B2/en active Active
- 2017-04-12 AR ARP170100939A patent/AR108130A1/es active IP Right Grant
- 2017-04-13 TW TW106112313A patent/TWI742067B/zh active
- 2017-04-18 UY UY0001037201A patent/UY37201A/es not_active Application Discontinuation
-
2018
- 2018-09-20 IL IL261885A patent/IL261885A/en unknown
- 2018-10-12 DO DO2018000226A patent/DOP2018000226A/es unknown
- 2018-10-12 CO CONC2018/0010966A patent/CO2018010966A2/es unknown
- 2018-10-12 CL CL2018002920A patent/CL2018002920A1/es unknown
- 2018-10-15 PH PH12018550173A patent/PH12018550173A1/en unknown
- 2018-11-14 ZA ZA2018/07656A patent/ZA201807656B/en unknown
-
2020
- 2020-01-29 US US16/776,377 patent/US10934301B2/en active Active
- 2020-01-29 US US16/776,374 patent/US11001590B2/en active Active
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