PL3442974T3 - Pochodne pirazolopirymidyny - Google Patents
Pochodne pirazolopirymidynyInfo
- Publication number
- PL3442974T3 PL3442974T3 PL17715204.8T PL17715204T PL3442974T3 PL 3442974 T3 PL3442974 T3 PL 3442974T3 PL 17715204 T PL17715204 T PL 17715204T PL 3442974 T3 PL3442974 T3 PL 3442974T3
- Authority
- PL
- Poland
- Prior art keywords
- pyrazolopyrimidine derivatives
- pyrazolopyrimidine
- derivatives
- Prior art date
Links
- OGEBRHQLRGFBNV-RZDIXWSQSA-N chembl2036808 Chemical class C12=NC(NCCCC)=NC=C2C(C=2C=CC(F)=CC=2)=NN1C[C@H]1CC[C@H](N)CC1 OGEBRHQLRGFBNV-RZDIXWSQSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16165572 | 2016-04-15 | ||
| PCT/EP2017/058519 WO2017178416A1 (en) | 2016-04-15 | 2017-04-10 | Pyrazolopyrimidine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3442974T3 true PL3442974T3 (pl) | 2023-12-04 |
Family
ID=55755480
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL17715204.8T PL3442974T3 (pl) | 2016-04-15 | 2017-04-10 | Pochodne pirazolopirymidyny |
Country Status (22)
| Country | Link |
|---|---|
| US (3) | US10604525B2 (pl) |
| EP (1) | EP3442974B8 (pl) |
| JP (1) | JP7051703B2 (pl) |
| KR (1) | KR102467347B1 (pl) |
| CN (1) | CN109071545B (pl) |
| AR (1) | AR108130A1 (pl) |
| AU (1) | AU2017251155B2 (pl) |
| CA (1) | CA3020793C (pl) |
| CL (1) | CL2018002920A1 (pl) |
| CO (1) | CO2018010966A2 (pl) |
| DO (1) | DOP2018000226A (pl) |
| ES (1) | ES2953467T3 (pl) |
| IL (1) | IL261885A (pl) |
| MX (1) | MX2018012544A (pl) |
| PH (1) | PH12018550173A1 (pl) |
| PL (1) | PL3442974T3 (pl) |
| RU (1) | RU2769448C2 (pl) |
| SG (1) | SG11201808214TA (pl) |
| TW (1) | TWI742067B (pl) |
| UY (1) | UY37201A (pl) |
| WO (1) | WO2017178416A1 (pl) |
| ZA (1) | ZA201807656B (pl) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MA44674B1 (fr) | 2016-04-15 | 2020-06-30 | Abbvie Inc | Inhibiteurs de bromodomaine |
| CN109071545B (zh) * | 2016-04-15 | 2021-08-03 | 拜耳动物保健有限责任公司 | 新的吡唑并嘧啶衍生物 |
| AU2018254577B2 (en) | 2017-04-21 | 2024-06-13 | Epizyme, Inc. | Combination therapies with EHMT2 inhibitors |
| US11130768B2 (en) * | 2017-04-27 | 2021-09-28 | Bayer Animal Health Gmbh | Bicyclic pyrazole derivatives |
| MA50256A (fr) | 2017-09-15 | 2020-07-22 | Aduro Biotech Inc | Composés de pyrazolopyrimidinone et leurs utilisations |
| SI3723739T1 (sl) | 2017-12-15 | 2024-08-30 | Tarsus Pharmaceuticals, Inc. | Paraziticidni pripravki na osnovi izoksazolina in njihova uporaba za zdravljenje blefaritisa |
| WO2019215182A1 (en) * | 2018-05-09 | 2019-11-14 | Bayer Animal Health Gmbh | New quinoline derivatives |
| EP3820870A1 (en) * | 2018-07-09 | 2021-05-19 | Boehringer Ingelheim Animal Health USA Inc. | Anthelminthic heterocyclic compounds |
| EP3643711A1 (en) * | 2018-10-24 | 2020-04-29 | Bayer Animal Health GmbH | New anthelmintic compounds |
| EP3897842A1 (en) * | 2018-12-18 | 2021-10-27 | Elanco Tiergesundheit AG | Bicyclic derivatives |
| AR116909A1 (es) * | 2018-12-18 | 2021-06-23 | Elanco Tiergesundheit Ag | Derivados bicíclicos |
| CA3133100A1 (en) * | 2019-03-19 | 2020-09-24 | Boehringer Ingelheim Animal Health USA Inc. | Anthelmintic aza-benzothiophene and aza-benzofuran compounds |
| CA3141905A1 (en) * | 2019-06-07 | 2020-12-10 | Elanco Tiergesundheit Ag | Bicyclic derivatives for treating endoparasites |
| TW202120490A (zh) * | 2019-07-30 | 2021-06-01 | 德商拜耳動物保健有限公司 | 新穎異喹啉衍生物 |
| AU2020404100A1 (en) * | 2019-12-18 | 2022-06-09 | Intervet International B.V. | Anthelmintic compounds comprising azaindoles structure |
| JP2023528822A (ja) | 2020-05-29 | 2023-07-06 | ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド | 駆虫性複素環式化合物 |
| WO2022106469A2 (en) | 2020-11-18 | 2022-05-27 | Elanco Tiergesundheit Ag | N-(2,3-dihydro-1,4-benzoxazin-4-yl)-3-isopropyl-7-(2,3,5-trifluorophenyl)benzo-thiophene-2-carboxamide derivatives and similar compounds for the treatment of heartworm infections |
| TW202237600A (zh) | 2020-12-04 | 2022-10-01 | 瑞士商禮藍動物保健股份有限公司 | 雙環衍生物 |
| AU2021395477A1 (en) | 2020-12-11 | 2023-06-22 | Intervet International B.V. | Anthelmintic compounds comprising a thienopyridine structure |
| CN113252824B (zh) * | 2021-06-17 | 2022-04-19 | 湖南农业大学 | 测定水体中三氟苯嘧啶含量的气相色谱-电子捕获检测器法 |
| KR102660894B1 (ko) * | 2021-09-17 | 2024-04-26 | 기초과학연구원 | 피리미딘-2-아민 화합물의 제조방법 |
| WO2023073641A1 (en) | 2021-11-01 | 2023-05-04 | Boehringer Ingelheim Vetmedica Gmbh | Anthelmintic pyrrolopyridazine compounds |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY125533A (en) * | 1999-12-06 | 2006-08-30 | Bristol Myers Squibb Co | Heterocyclic dihydropyrimidine compounds |
| RU15525U1 (ru) | 2000-07-04 | 2000-10-20 | Федеральный научно-производственный центр закрытое акционерное общество "Научно-производственный концерн (объединение) "ЭНЕРГИЯ" | Электродвигатель постоянного тока |
| WO2003091256A1 (fr) | 2002-04-23 | 2003-11-06 | Shionogi & Co., Ltd. | Derive de pyrazolo[1,5-a]pyrimidine et inhibiteur de la nad(p)h oxydase contenant ledit derive |
| GB0213715D0 (en) | 2002-06-14 | 2002-07-24 | Syngenta Ltd | Chemical compounds |
| TWI312272B (en) | 2003-05-12 | 2009-07-21 | Sumitomo Chemical Co | Pyrimidine compound and pests controlling composition containing the same |
| EA009517B1 (ru) * | 2003-06-27 | 2008-02-28 | Байер Кропсайенс Аг | Пиразолопиримидины |
| KR20060027809A (ko) | 2003-06-27 | 2006-03-28 | 바이엘 크롭사이언스 아게 | 피라졸로피리미딘 |
| GB0414438D0 (en) | 2004-06-28 | 2004-07-28 | Syngenta Participations Ag | Chemical compounds |
| MX2007004710A (es) | 2004-10-20 | 2007-06-14 | Kumiai Chemical Industry Co | Derivado de sulfuro de 3-triazolilfenilo e insecticida/acaricida/ nematicida que contiene el mismo como ingrediente activo. |
| EA014057B1 (ru) | 2005-10-06 | 2010-08-30 | Ниппон Сода Ко., Лтд. | Поперечно связанные соединения циклических аминов и средства для борьбы с вредителями |
| EP1918291A1 (en) * | 2006-10-30 | 2008-05-07 | Novartis AG | 3-Aminocarbonyl-substituted fused pyrazolo-derivatives as protein kinase modulators |
| WO2008063671A2 (en) * | 2006-11-20 | 2008-05-29 | Alantos Pharmaceuticals Holding, Inc. | Heterobicyclic metalloprotease inhibitors |
| WO2009041663A1 (ja) | 2007-09-28 | 2009-04-02 | Kyowa Hakko Kirin Co., Ltd. | 皮膚疾患の予防及び／または治療剤 |
| JP5268461B2 (ja) | 2008-07-14 | 2013-08-21 | Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 | Ｐｆ１３６４物質、その製造方法、生産菌株、及び、それを有効成分とする農園芸用殺虫剤 |
| CN101337937B (zh) | 2008-08-12 | 2010-12-22 | 国家农药创制工程技术研究中心 | 具有杀虫活性的n-苯基-5-取代氨基吡唑类化合物 |
| CN101337940B (zh) | 2008-08-12 | 2012-05-02 | 国家农药创制工程技术研究中心 | 具杀虫活性的含氮杂环二氯烯丙醚类化合物 |
| CN101715774A (zh) | 2008-10-09 | 2010-06-02 | 浙江化工科技集团有限公司 | 一个具有杀虫活性化合物制备及用途 |
| EP2184273A1 (de) | 2008-11-05 | 2010-05-12 | Bayer CropScience AG | Halogen-substituierte Verbindungen als Pestizide |
| GB0820344D0 (en) | 2008-11-06 | 2008-12-17 | Syngenta Ltd | Herbicidal compositions |
| US8007468B2 (en) | 2009-07-13 | 2011-08-30 | Navilyst Medical, Inc. | Method to secure an elastic component in a valve |
| WO2011085575A1 (zh) | 2010-01-15 | 2011-07-21 | 江苏省农药研究所股份有限公司 | 邻杂环甲酰苯胺类化合物及其合成方法和应用 |
| EP2959775A1 (en) | 2010-08-31 | 2015-12-30 | Meiji Seika Pharma Co., Ltd. | Pest control agent |
| CN101967139B (zh) | 2010-09-14 | 2013-06-05 | 中化蓝天集团有限公司 | 一种含一氟甲氧基吡唑的邻甲酰氨基苯甲酰胺类化合物、其合成方法及应用 |
| EP2675440B1 (en) | 2011-02-14 | 2020-03-25 | Merck Sharp & Dohme Corp. | Cathepsin cysteine protease inhibitors |
| WO2013050317A1 (en) | 2011-10-03 | 2013-04-11 | Syngenta Limited | Polymorphs of an isoxazoline derivative |
| CN102391261A (zh) | 2011-10-14 | 2012-03-28 | 上海交通大学 | 一种n-取代噁二嗪类化合物及其制备方法和应用 |
| US9334238B2 (en) | 2012-03-30 | 2016-05-10 | Basf Se | N-substituted pyridinylidenes for combating animal pests |
| EP2647626A1 (en) | 2012-04-03 | 2013-10-09 | Syngenta Participations AG. | 1-Aza-spiro[4.5]dec-3-ene and 1,8-diaza-spiro[4.5]dec-3-ene derivatives as pesticides |
| BR112014026746A2 (pt) | 2012-04-27 | 2017-06-27 | Dow Agrosciences Llc | composições pesticidas e processos relacionados com as mesmas |
| US9282739B2 (en) | 2012-04-27 | 2016-03-15 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
| EP2914591B1 (en) | 2012-11-03 | 2017-10-11 | Boehringer Ingelheim International GmbH | Inhibitors of cytomegalovirus |
| CN103232431B (zh) | 2013-01-25 | 2014-11-05 | 青岛科技大学 | 一种二卤代吡唑酰胺类化合物及其应用 |
| CN103109816B (zh) | 2013-01-25 | 2014-09-10 | 青岛科技大学 | 硫代苯甲酰胺类化合物及其应用 |
| US20140275503A1 (en) | 2013-03-13 | 2014-09-18 | Dow Agrosciences Llc | Process for the preparation of certain triaryl rhamnose carbamates |
| CN103265527B (zh) | 2013-06-07 | 2014-08-13 | 江苏省农用激素工程技术研究中心有限公司 | 邻氨基苯甲酰胺化合物及其制备方法和应用 |
| CN103524422B (zh) | 2013-10-11 | 2015-05-27 | 中国农业科学院植物保护研究所 | 苯并咪唑衍生物及其制备方法和用途 |
| MX2016004942A (es) | 2013-10-17 | 2016-06-28 | Dow Agrosciences Llc | Procesos para la preparacion de compuestos plaguicidas. |
| CN105636440A (zh) | 2013-10-17 | 2016-06-01 | 美国陶氏益农公司 | 制备杀虫化合物的方法 |
| UY36196A (es) * | 2014-07-25 | 2016-02-29 | Bayer Animal Health Gmbh | Compuestos para usar en el tratamiento antihelmíntico |
| CN109071545B (zh) | 2016-04-15 | 2021-08-03 | 拜耳动物保健有限责任公司 | 新的吡唑并嘧啶衍生物 |
-
2017
- 2017-04-10 CN CN201780023855.8A patent/CN109071545B/zh active Active
- 2017-04-10 ES ES17715204T patent/ES2953467T3/es active Active
- 2017-04-10 MX MX2018012544A patent/MX2018012544A/es unknown
- 2017-04-10 WO PCT/EP2017/058519 patent/WO2017178416A1/en active Application Filing
- 2017-04-10 JP JP2018553486A patent/JP7051703B2/ja active Active
- 2017-04-10 RU RU2018140092A patent/RU2769448C2/ru active
- 2017-04-10 US US16/093,565 patent/US10604525B2/en active Active
- 2017-04-10 PL PL17715204.8T patent/PL3442974T3/pl unknown
- 2017-04-10 EP EP17715204.8A patent/EP3442974B8/en active Active
- 2017-04-10 CA CA3020793A patent/CA3020793C/en active Active
- 2017-04-10 KR KR1020187032684A patent/KR102467347B1/ko active IP Right Grant
- 2017-04-10 AU AU2017251155A patent/AU2017251155B2/en active Active
- 2017-04-10 SG SG11201808214TA patent/SG11201808214TA/en unknown
- 2017-04-12 AR ARP170100939A patent/AR108130A1/es unknown
- 2017-04-13 TW TW106112313A patent/TWI742067B/zh active
- 2017-04-18 UY UY0001037201A patent/UY37201A/es not_active Application Discontinuation
-
2018
- 2018-09-20 IL IL261885A patent/IL261885A/en unknown
- 2018-10-12 CO CONC2018/0010966A patent/CO2018010966A2/es unknown
- 2018-10-12 DO DO2018000226A patent/DOP2018000226A/es unknown
- 2018-10-12 CL CL2018002920A patent/CL2018002920A1/es unknown
- 2018-10-15 PH PH12018550173A patent/PH12018550173A1/en unknown
- 2018-11-14 ZA ZA2018/07656A patent/ZA201807656B/en unknown
-
2020
- 2020-01-29 US US16/776,374 patent/US11001590B2/en active Active
- 2020-01-29 US US16/776,377 patent/US10934301B2/en active Active
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