|
NL7503310A
(nl)
*
|
1975-03-20 |
1976-09-22 |
Philips Nv |
Verbindingen met antidepressieve werking.
|
|
GB1526331A
(en)
*
|
1976-01-14 |
1978-09-27 |
Kefalas As |
Phthalanes
|
|
KR19990022524A
(ko)
|
1995-06-06 |
1999-03-25 |
웨인스톡 스티븐 에프. |
퀴놀리지논형화합물
|
|
GB9519563D0
(en)
|
1995-09-26 |
1995-11-29 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
AU3555200A
(en)
|
1999-03-17 |
2000-10-04 |
F. Hoffmann-La Roche Ag |
Oxazolone derivatives and their use as alpha-1 adrenoreceptor modulators
|
|
US6375897B1
(en)
|
2000-02-14 |
2002-04-23 |
Ansys Technologies, Inc. |
Urine collection cup
|
|
MY145722A
(en)
|
2000-04-27 |
2012-03-30 |
Abbott Lab |
Diazabicyclic central nervous system active agents
|
|
US6809105B2
(en)
|
2000-04-27 |
2004-10-26 |
Abbott Laboratories |
Diazabicyclic central nervous system active agents
|
|
WO2001085693A1
(en)
|
2000-05-11 |
2001-11-15 |
Banyu Pharmaceutical Co., Ltd. |
N-acyltetrahydroisoquinoline derivatives
|
|
SE0100326D0
(sv)
|
2001-02-02 |
2001-02-02 |
Astrazeneca Ab |
New compounds
|
|
WO2002070527A1
(en)
|
2001-03-02 |
2002-09-12 |
Akzo Nobel N.V. |
Mass-selective purification of organometallics
|
|
WO2002070523A1
(en)
|
2001-03-07 |
2002-09-12 |
Pfizer Products Inc. |
Modulators of chemokine receptor activity
|
|
US7470710B2
(en)
|
2001-06-28 |
2008-12-30 |
Smithkline Beecham P.L.C. |
N-aroyl cyclic amine derivatives as orexin receptor antagonists
|
|
US6455722B1
(en)
|
2001-06-29 |
2002-09-24 |
Pabu Services, Inc. |
Process for the production of pentaerythritol phosphate alcohol
|
|
GB2383315B
(en)
|
2001-12-18 |
2005-04-06 |
Christopher Donald Clarke |
Vehicle imaging system
|
|
GB0130341D0
(en)
|
2001-12-19 |
2002-02-06 |
Smithkline Beecham Plc |
Compounds
|
|
DE10226943A1
(de)
|
2002-06-17 |
2004-01-08 |
Bayer Ag |
Phenylaminopyrimidine und ihre Verwendung
|
|
JP4498922B2
(ja)
|
2002-07-09 |
2010-07-07 |
アクテリオン ファーマシューティカルズ リミテッド |
７，８，９，１０−テトラヒドロ−６Ｈ−アゼピノ、６，７，８，９−テトラヒドロ−ピリドおよび２，３−ジヒドロ−２Ｈ−ピロロ［２，１−ｂ］−キナゾリノン誘導体
|
|
NZ538749A
(en)
|
2002-10-11 |
2006-11-30 |
Actelion Pharmaceuticals Ltd |
Sulfonylamino-acetic acid derivatives and their use as orexin receptor antagonists
|
|
GB0225944D0
(en)
|
2002-11-06 |
2002-12-11 |
Glaxo Group Ltd |
Novel compounds
|
|
RU2345985C2
(ru)
|
2003-03-26 |
2009-02-10 |
Актелион Фармасьютиклз Лтд. |
Производные тетрагидроизохинолилацетамида в качестве антагонистов орексинового рецептора
|
|
ATE383345T1
(de)
|
2003-04-28 |
2008-01-15 |
Actelion Pharmaceuticals Ltd |
Quinoxalin-3-on-verdindungen als orexin-rezeptor antagonisten.
|
|
US20040242641A1
(en)
|
2003-05-27 |
2004-12-02 |
Buckley Michael J. |
(1S,5S)-3-(5,6-dichloro-3-pyridinyl)-3,6-diazabicyclo[3.2.0]heptane is an effective analgesic agent
|
|
WO2005005439A1
(en)
|
2003-07-09 |
2005-01-20 |
Suven Life Sciences Limited |
Benzothiazino indoles
|
|
TW200507850A
(en)
*
|
2003-07-25 |
2005-03-01 |
Kyowa Hakko Kogyo Kk |
Pharmaceutical composition
|
|
WO2005023231A1
(en)
|
2003-09-10 |
2005-03-17 |
MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. |
Polypyrimidine tract binding protein promotes insulin secretory granule biogenesis
|
|
US7399765B2
(en)
|
2003-09-19 |
2008-07-15 |
Abbott Laboratories |
Substituted diazabicycloalkane derivatives
|
|
US20050065178A1
(en)
|
2003-09-19 |
2005-03-24 |
Anwer Basha |
Substituted diazabicycloakane derivatives
|
|
PT1691811E
(pt)
|
2003-12-11 |
2014-10-30 |
Sunovion Pharmaceuticals Inc |
Combinação de um sedativo e de um modulador de neurotransmissores e métodos para melhorar a qualidade do sono e tratamento da depressão
|
|
HUP0400405A3
(en)
|
2004-02-10 |
2009-03-30 |
Sanofi Synthelabo |
Pyrimidine derivatives, process for producing them, their use, pharmaceutical compositions containing them and their intermediates
|
|
RU2378257C2
(ru)
|
2004-03-01 |
2010-01-10 |
Актелион Фармасьютиклз Лтд |
Замещенные производные 1,2,3,4-тетрагидроизохинолина
|
|
AU2005219438B2
(en)
|
2004-03-03 |
2011-02-17 |
Chemocentryx, Inc. |
Bicyclic and bridged nitrogen heterocycles
|
|
US7435831B2
(en)
|
2004-03-03 |
2008-10-14 |
Chemocentryx, Inc. |
Bicyclic and bridged nitrogen heterocycles
|
|
WO2006012396A1
(en)
|
2004-07-22 |
2006-02-02 |
Glaxo Group Limited |
Antibacterial agents
|
|
CA2574307A1
(en)
|
2004-07-22 |
2006-02-02 |
Cumbre Pharmaceuticals Inc. |
Rifamycin derivatives for treating microbial infections
|
|
FR2874011B1
(fr)
|
2004-08-03 |
2007-06-15 |
Sanofi Synthelabo |
Derives de sulfonamides, leur preparation et leur application en therapeutique
|
|
US20080009477A1
(en)
|
2004-11-04 |
2008-01-10 |
Neurogen Corporation |
Arylalkyl Ureas As Cb1 Antagonists
|
|
EP1846409A1
(en)
|
2004-11-24 |
2007-10-24 |
Pfizer Limited |
Octahydropyrrolo[3,4-c]pyrrole derivatives
|
|
DE102004061344A1
(de)
|
2004-12-20 |
2006-07-06 |
Siemens Ag |
Verfahren zur sicheren Auslegung eines Systems, zugehörige Systemkomponente und Software
|
|
CN101193635A
(zh)
*
|
2005-05-13 |
2008-06-04 |
莱西肯医药有限公司 |
多环化合物及其使用方法
|
|
WO2006124897A2
(en)
|
2005-05-13 |
2006-11-23 |
Lexicon Genetics Incorporated |
Methods and compositions for improving cognition
|
|
GB0510204D0
(en)
|
2005-05-19 |
2005-06-22 |
Chroma Therapeutics Ltd |
Enzyme inhibitors
|
|
US20080175795A1
(en)
|
2005-06-30 |
2008-07-24 |
Bexel Pharmaceuticals, Inc. |
Novel derivatives of amino acids for treatment of obesity and related disorders
|
|
GB0514018D0
(en)
|
2005-07-07 |
2005-08-17 |
Ionix Pharmaceuticals Ltd |
Chemical compounds
|
|
JP2009506061A
(ja)
|
2005-08-26 |
2009-02-12 |
メルク エンド カムパニー インコーポレーテッド |
ジアザスピロデカンオレキシン受容体拮抗薬
|
|
FR2896798A1
(fr)
|
2006-01-27 |
2007-08-03 |
Sanofi Aventis Sa |
Derives de sulfonamides, leur preparation et leur application en therapeutique
|
|
FR2896799B1
(fr)
|
2006-02-02 |
2008-03-28 |
Sanofi Aventis Sa |
Derives de sulfonamides, leur preparation et leur application en therapeutique
|
|
US7553836B2
(en)
|
2006-02-06 |
2009-06-30 |
Bristol-Myers Squibb Company |
Melanin concentrating hormone receptor-1 antagonists
|
|
JP2009531447A
(ja)
|
2006-03-29 |
2009-09-03 |
メルク エンド カムパニー インコーポレーテッド |
ジアゼパンオレキシン受容体アンタゴニスト
|
|
US20090105318A1
(en)
|
2006-03-29 |
2009-04-23 |
Coleman Paul J |
Amidoethylthioether Orexin Receptor Antagonists
|
|
DE602007012072D1
(de)
|
2006-04-26 |
2011-03-03 |
Actelion Pharmaceuticals Ltd |
Orantagonisten
|
|
WO2007146761A2
(en)
|
2006-06-12 |
2007-12-21 |
Neurogen Corporation |
Diaryl pyrimidinones and related compounds
|
|
SI2049529T1
(sl)
|
2006-07-14 |
2010-11-30 |
Merck Sharp & Dohme |
Substituiran diazepan oreksin receptor antagonist
|
|
EP2049526A2
(en)
|
2006-07-14 |
2009-04-22 |
Merck & Co., Inc. |
2-substituted proline bis-amide orexin receptor antagonists
|
|
EP2049110B1
(en)
|
2006-07-14 |
2014-08-20 |
Merck Sharp & Dohme Corp. |
Bridged diazepan orexin receptor antagonists
|
|
CA2659299A1
(en)
|
2006-08-15 |
2008-02-21 |
Actelion Pharmaceuticals Ltd |
Azetidine compounds
|
|
ATE458740T1
(de)
|
2006-08-28 |
2010-03-15 |
Actelion Pharmaceuticals Ltd |
1,4,5,6,7,8-hexahydro-1,2,5-triaza-azulen- derivate als orexinrezeptor-antagonisten
|
|
ES2345130T3
(es)
|
2006-09-18 |
2010-09-15 |
F. Hoffmann-La Roche Ag |
Derivados de octahidropirrolo(3,4-c)pirrol y su uso como antiviricos.
|
|
CL2007002809A1
(es)
|
2006-09-29 |
2008-04-18 |
Actelion Pharmaceuticals Ltd |
Compuestos derivados de 3-aza biciclo [3.1.0]hexano; y su uso en el tratamiento de enfermedades tales como desordenes psicoticos y de ansiedad, desordenes del sueno, uso y abuso de sustancias psicoactivas, demencia y deterioro de funciones cognitivas
|
|
US20100105614A1
(en)
|
2006-10-25 |
2010-04-29 |
Somaxon Pharmaceuticals, Inc. |
Ultra low dose doxepin and methods of using the same to treat sleep disorders
|
|
US20080153811A1
(en)
|
2006-11-07 |
2008-06-26 |
Joseph Barbosa |
Methods of Treating Cognitive Impairment and Dementia
|
|
PE20081229A1
(es)
|
2006-12-01 |
2008-08-28 |
Merck & Co Inc |
Antagonistas de receptor de orexina de diazepam sustituido
|
|
WO2008070795A2
(en)
|
2006-12-06 |
2008-06-12 |
Somaxon Pharmaceuticals, Inc. |
Combination therapy using low-dose doxepin for the improvement of sleep
|
|
AU2007337659A1
(en)
|
2006-12-22 |
2008-07-03 |
Actelion Pharmaceuticals Ltd. |
5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazine derivatives
|
|
CL2008000836A1
(es)
|
2007-03-26 |
2008-11-07 |
Actelion Pharmaceuticals Ltd |
Compuestos derivados de tiazolidina, antagonistas del receptor de orexina; composicion farmaceutica que los comprende; y su uso en el tratamiento de neurosis emocional, depresion grave, trastornos psicoticos, alzheimer, parkinson, dolor, entre otras.
|
|
US7851622B2
(en)
|
2007-04-25 |
2010-12-14 |
Bristol-Myers Squibb Company |
Non-basic melanin concentrating hormone receptor-1 antagonists
|
|
WO2008143856A1
(en)
|
2007-05-18 |
2008-11-27 |
Merck & Co., Inc. |
Oxo bridged diazepan orexin receptor antagonists
|
|
FR2918061B1
(fr)
|
2007-06-28 |
2010-10-22 |
Sanofi Aventis |
Derives de 6-cycloamino-3-(pyridin-4-yl)imidazo°1,2-b!- pyridazine,leur preparation et leur application en therapeutique.
|
|
EP2176258A1
(en)
|
2007-07-03 |
2010-04-21 |
Glaxo Group Limited |
Piperidine derivatives useful as orexin receptor antagonists
|
|
US8106215B2
(en)
|
2007-07-03 |
2012-01-31 |
Actelion Pharmaceuticals Ltd. |
3-aza-bicyclo[3.3.0]octane compounds
|
|
GB0712888D0
(en)
|
2007-07-03 |
2007-08-15 |
Glaxo Group Ltd |
Novel compounds
|
|
US20090011994A1
(en)
|
2007-07-06 |
2009-01-08 |
Bristol-Myers Squibb Company |
Non-basic melanin concentrating hormone receptor-1 antagonists and methods
|
|
WO2009011775A1
(en)
|
2007-07-13 |
2009-01-22 |
Merck & Co., Inc. |
Amidoethyl alkylamino orexin receptor antagonists
|
|
FR2918986B1
(fr)
|
2007-07-19 |
2009-09-04 |
Sanofi Aventis Sa |
Derives de 6-cycloamino-3-(pyridazin-4-yl)imidazo[1,2-b]- pyridazine, leur preparation et leur application en therapeutique
|
|
KR20100046047A
(ko)
|
2007-07-27 |
2010-05-04 |
액테리온 파마슈티칼 리미티드 |
2-아자-비시클로[3.3.0]옥탄 유도체
|
|
BRPI0814767A2
(pt)
|
2007-08-02 |
2015-03-03 |
Hoffmann La Roche |
Derivados de monoamida como antagonistas do receptor de orexina
|
|
ES2400830T3
(es)
|
2007-08-15 |
2013-04-12 |
Actelion Pharmaceuticals Ltd. |
Derivados de 1,2-diamido-etileno como antagonistas de orexina
|
|
US8288411B2
(en)
|
2007-09-24 |
2012-10-16 |
Actelion Pharmaceuticals Ltd. |
Pyrrolidines and piperidines as orexin receptor antagonists
|
|
EP2214676B1
(en)
|
2007-10-29 |
2012-11-21 |
Merck Sharp & Dohme Corp. |
Substituted diazepan orexin receptor antagonists
|
|
EP2058001A1
(en)
|
2007-11-08 |
2009-05-13 |
Crossbeta Biosciences B.V. |
Enhancement of immunogenicity of antigens
|
|
CN101952286A
(zh)
|
2007-12-21 |
2011-01-19 |
阿斯利康(瑞典)有限公司 |
用于治疗和雄激素受体有关的病症的双环衍生物
|
|
KR101204213B1
(ko)
|
2007-12-21 |
2012-11-26 |
에프. 호프만-라 로슈 아게 |
오렉신 수용체 길항제로서의 헤테로아릴 유도체
|
|
GB0806536D0
(en)
|
2008-04-10 |
2008-05-14 |
Glaxo Group Ltd |
Novel compounds
|
|
CA2725342C
(en)
|
2008-05-27 |
2024-02-20 |
Intra-Cellular Therapies, Inc. |
Substituted heterocycle fused gamma-carbolines for sleep disorders and other disorders
|
|
JP5301665B2
(ja)
|
2008-07-29 |
2013-09-25 |
エフ．ホフマン−ラ ロシュ アーゲー |
オレキシンアンタゴニストとしてのピロリジン−３−イルメチル−アミン
|
|
AR072899A1
(es)
|
2008-08-07 |
2010-09-29 |
Merck Sharp & Dohme |
Derivados de terpiridina-carboxamida antagonistas de receptores de orexina, composiciones farmaceuticas que los contienen y uso de los mismos en el tratamiento del insomnio y la obesidad.
|
|
US8093255B2
(en)
|
2008-10-09 |
2012-01-10 |
Glaxo Group Limited |
Imidazo[1,2-A]pyrimidines as orexin receptor antagonists
|
|
US8129384B2
(en)
|
2008-10-09 |
2012-03-06 |
Glaxo Group Limited |
Imidazo[1,2-a]pyrazines as orexin receptor antagonists
|
|
US20100267730A1
(en)
|
2008-10-09 |
2010-10-21 |
Giuseppe Alvaro |
Novel compounds
|
|
AU2009307915A1
(en)
|
2008-10-21 |
2010-04-29 |
Merck Sharp & Dohme Corp. |
2,5-disubstituted piperidine orexin receptor antagonists
|
|
AU2009307918A1
(en)
|
2008-10-21 |
2010-04-29 |
Merck Sharp & Dohme Corp. |
2,4-disubstituted pyrrolidine orexin receptor antagonists
|
|
AU2009307921A1
(en)
|
2008-10-21 |
2010-04-29 |
Merck Sharp & Dohme Corp. |
Disubstituted azepan orexin receptor antagonists
|
|
AU2009307920A1
(en)
|
2008-10-21 |
2010-04-29 |
Merck Sharp & Dohme Corp. |
2,3-disubstituted piperidine orexin receptor antagonists
|
|
JP2012506374A
(ja)
|
2008-10-21 |
2012-03-15 |
メルク・シャープ・エンド・ドーム・コーポレイション |
２，５−二置換ピペリジンオレキシン受容体アンタゴニスト
|
|
WO2010048013A1
(en)
|
2008-10-21 |
2010-04-29 |
Merck Sharp & Dohme Corp. |
2,5-disubstituted morpholine orexin receptor antagonists
|
|
EP2349262B1
(en)
|
2008-10-30 |
2014-06-25 |
Merck Sharp & Dohme Corp. |
2,5-disubstituted phenyl carboxamide orexin receptor antagonists
|
|
EP2349267B1
(en)
|
2008-10-30 |
2014-06-25 |
Merck Sharp & Dohme Corp. |
Pyridazine carboxamide orexin receptor antagonists
|
|
MX2011004551A
(es)
|
2008-10-30 |
2011-05-25 |
Merck Sharp & Dohme |
Antagonistas del receptor de orexina de isonicotinamida.
|
|
WO2010060470A1
(en)
|
2008-11-26 |
2010-06-03 |
Glaxo Group Limited |
Piperidine derivatives useful as orexin receptor antagonists
|
|
JP2012509912A
(ja)
|
2008-11-26 |
2012-04-26 |
グラクソ グループ リミテッド |
新規の化合物
|
|
EP2358712A1
(en)
|
2008-11-26 |
2011-08-24 |
Glaxo Group Limited |
Piperidine derivatives useful as orexin receptor antagonists
|
|
CA2745433A1
(en)
|
2008-12-02 |
2010-06-10 |
Glaxo Group Ltd. |
N-{[(ir,4s,6r-3-(2-pyridinylcarbonyl)-3-azabicyclo [4.1.0]hept-4-yl] methyl}-2-heteroarylamine derivatives and uses thereof
|
|
KR20110091581A
(ko)
|
2008-12-02 |
2011-08-11 |
글락소 그룹 리미티드 |
Ｎ-｛［1ｒ,4ｓ,6ｒ-3-(2-피리디닐카르보닐)-3-아자비시클로［4.1.0］헵트-4-일］메틸｝-2-헤테로아릴아민 유도체 및 그의 용도
|
|
GB0823467D0
(en)
|
2008-12-23 |
2009-01-28 |
Glaxo Group Ltd |
Novel Compounds
|
|
US20100214135A1
(en)
|
2009-02-26 |
2010-08-26 |
Microsoft Corporation |
Dynamic rear-projected user interface
|
|
CN102459229A
(zh)
|
2009-04-24 |
2012-05-16 |
葛兰素集团有限公司 |
用作食欲肽拮抗剂的3-氮杂二环[4.1.0]庚烷
|
|
EP2470523A1
(en)
|
2009-08-24 |
2012-07-04 |
Glaxo Group Limited |
5-methyl-piperidine derivatives as orexin receptor antagonists for the treatment of sleep disorder
|
|
US20120149711A1
(en)
|
2009-08-24 |
2012-06-14 |
Glaxo Group Limited |
Piperidine derivatives used as orexin antagonists
|
|
ME03452B
(me)
|
2009-10-23 |
2020-01-20 |
Janssen Pharmaceutica Nv |
Disupstituisani oktahi-dropirolo[3,4-c]piroli kao modulatori oreksin receptora
|
|
EP2491031B1
(en)
|
2009-10-23 |
2013-08-07 |
Janssen Pharmaceutica N.V. |
Fused heterocyclic compounds as orexin receptor modulators
|
|
EP2491034B1
(en)
|
2009-10-23 |
2013-12-18 |
Janssen Pharmaceutica, N.V. |
Fused heterocyclic compounds as orexin receptor modulators
|
|
CA2778613C
(en)
|
2009-10-24 |
2018-11-27 |
Indiana University Research And Technology Corporation |
Methods and compositions for panic disorders
|
|
TWI410630B
(zh)
|
2009-11-10 |
2013-10-01 |
晟德大藥廠股份有限公司 |
一種用以治療與食慾素受體１、食慾素受體２、體抑素受體２或多巴胺ｄ２ｌ受體相關之疾病的方法和組合物
|
|
WO2011079274A1
(en)
*
|
2009-12-23 |
2011-06-30 |
Jasco Pharmaceuticals, LLC |
Aminopyrimidine kinase inhibitors
|
|
MX2013006715A
(es)
|
2010-12-17 |
2013-08-26 |
Taisho Pharmaceutical Co Ltd |
Derivado de pirazol.
|
|
WO2012089607A1
(en)
|
2010-12-28 |
2012-07-05 |
Glaxo Group Limited |
Novel compounds with a 3a-azabicyclo [4.1.0] heptane core acting on orexin receptors
|
|
WO2012089606A1
(en)
|
2010-12-28 |
2012-07-05 |
Glaxo Group Limited |
Azabicyclo [4.1.0] hept - 4 - yl derivatives as human orexin receptor antagonists
|
|
WO2012145581A1
(en)
*
|
2011-04-20 |
2012-10-26 |
Janssen Pharmaceutica Nv |
Disubstituted octahy-dropyrrolo [3,4-c] pyrroles as orexin receptor modulators
|
|
US20140081025A1
(en)
|
2011-05-10 |
2014-03-20 |
Taisho Pharmaceutical Co., Ltd. |
Heteroaromatic ring derivative
|
|
EP2730573A4
(en)
|
2011-07-05 |
2014-12-03 |
Taisho Pharmaceutical Co Ltd |
METHYLPIPERIDINDERIVAT
|
|
WO2013059163A1
(en)
|
2011-10-21 |
2013-04-25 |
Merck Sharp & Dohme Corp. |
2,5-disubstituted thiomorpholine orexin receptor antagonists
|
|
JP6346862B2
(ja)
|
2012-02-07 |
2018-06-20 |
エオラス セラピューティクス， インコーポレイテッド |
オレキシンレセプターアンタゴニストとしての置換プロリン／ピペリジン
|
|
US9440982B2
(en)
|
2012-02-07 |
2016-09-13 |
Eolas Therapeutics, Inc. |
Substituted prolines/piperidines as orexin receptor antagonists
|
|
US9493481B2
(en)
|
2012-02-23 |
2016-11-15 |
Vanderbilt University |
Substituted 5-aminothieno[2,3—C]pyridazine-6-carboxamide analogs as positive allosteric modulators of the muscarinic acetylcholine receptor M4
|
|
ES2613663T3
(es)
|
2012-06-15 |
2017-05-25 |
Taisho Pharmaceutical Co., Ltd. |
Compuestos de 1,3-oxazolidina o 1,3-oxazinano como antagonistas del receptor de orexina
|
|
KR20150023390A
(ko)
|
2012-06-15 |
2015-03-05 |
다이쇼 세이야꾸 가부시끼가이샤 |
분지쇄 알킬 헤테로 방향환 유도체
|
|
JP2014015452A
(ja)
|
2012-06-15 |
2014-01-30 |
Taisho Pharmaceutical Co Ltd |
ピラゾール誘導体を含有する医薬
|
|
JP2014111586A
(ja)
|
2012-11-09 |
2014-06-19 |
Taisho Pharmaceutical Co Ltd |
ヘテロ芳香環誘導体を含有する医薬
|
|
US9624197B2
(en)
|
2012-11-27 |
2017-04-18 |
Merck Sharp & Dohme Corp. |
2-pyridylamino-4-nitrile-piperidinyl orexin receptor antagonists
|
|
JP2016028017A
(ja)
|
2012-12-13 |
2016-02-25 |
大正製薬株式会社 |
フッ素置換ピペリジン化合物
|
|
JP2014141480A
(ja)
|
2012-12-28 |
2014-08-07 |
Taisho Pharmaceutical Co Ltd |
メチルピペリジン誘導体を含有する医薬
|
|
TWI621618B
(zh)
|
2013-03-13 |
2018-04-21 |
比利時商健生藥品公司 |
經取代２－氮雜雙環類及其作為食慾素受體調控劑之用途
|
|
WO2015018027A1
(en)
|
2013-08-08 |
2015-02-12 |
Merck Sharp & Dohme Corp. |
Thiazole orexin receptor antagonists
|
|
KR102967223B1
(ko)
|
2013-12-03 |
2026-05-19 |
인트라-셀룰라 써래피스, 인코퍼레이티드. |
신규한 방법
|
|
US9586934B2
(en)
|
2013-12-09 |
2017-03-07 |
Merck Sharp & Dohme Corp. |
2-pyridyloxy-4-methyl orexin receptor antagonists
|
|
JP2015131802A
(ja)
|
2013-12-13 |
2015-07-23 |
大正製薬株式会社 |
分岐鎖アルキルヘテロ芳香環誘導体を含有する医薬
|
|
JP5930010B2
(ja)
|
2013-12-13 |
2016-06-08 |
大正製薬株式会社 |
ヘテロ芳香環メチル環状アミン誘導体を含有する医薬
|
|
WO2015095108A1
(en)
*
|
2013-12-18 |
2015-06-25 |
Merck Sharp & Dohme Corp. |
Thioether-piperidinyl orexin receptor antagonists
|
|
TW201613891A
(en)
|
2014-02-12 |
2016-04-16 |
Eolas Therapeutics Inc |
Substituted prolines / piperidines as orexin receptor antagonists
|
|
TW201613864A
(en)
|
2014-02-20 |
2016-04-16 |
Takeda Pharmaceutical |
Novel compounds
|
|
JP2017100950A
(ja)
|
2014-04-04 |
2017-06-08 |
大正製薬株式会社 |
オキソ複素環誘導体
|
|
JP2017100951A
(ja)
|
2014-04-04 |
2017-06-08 |
大正製薬株式会社 |
オキサゾリジノン及びオキサジナノン誘導体
|
|
WO2015180060A1
(zh)
|
2014-05-28 |
2015-12-03 |
杭州普晒医药科技有限公司 |
一种二氮杂环庚烷化合物的盐及其晶型与无定型物
|
|
TW201613902A
(en)
|
2014-08-13 |
2016-04-16 |
Eolas Therapeutics Inc |
Difluoropyrrolidines as orexin receptor modulators
|
|
US20160051533A1
(en)
|
2014-08-20 |
2016-02-25 |
Ladd Research LLC |
Diagnosis and pharmacological treatment of seasonal affective disorder and symptoms of seasonality
|
|
GB201415569D0
(en)
|
2014-09-03 |
2014-10-15 |
C4X Discovery Ltd |
Therapeutic Compounds
|
|
US10196383B2
(en)
|
2015-07-17 |
2019-02-05 |
Sunshine Lake Pharma Co., Ltd. |
Substituted quinazoline compounds and preparation and uses thereof
|
|
GB201601703D0
(en)
|
2016-01-29 |
2016-03-16 |
C4X Discovery Ltd |
Therapeutic compounds
|
|
KR20230116948A
(ko)
*
|
2016-03-10 |
2023-08-04 |
얀센 파마슈티카 엔.브이. |
오렉신-2 수용체 길항제를 사용한 우울증의 치료 방법
|
|
GB201820458D0
(en)
|
2018-12-14 |
2019-01-30 |
Heptares Therapeutics Ltd |
Ox1 antagonists
|