JP2002523491A5 - - Google Patents

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Publication number
JP2002523491A5
JP2002523491A5 JP2000567508A JP2000567508A JP2002523491A5 JP 2002523491 A5 JP2002523491 A5 JP 2002523491A5 JP 2000567508 A JP2000567508 A JP 2000567508A JP 2000567508 A JP2000567508 A JP 2000567508A JP 2002523491 A5 JP2002523491 A5 JP 2002523491A5
Authority
JP
Japan
Prior art keywords
compound
propylamine
disorder
hydrogen
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000567508A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002523491A (ja
Filing date
Publication date
Priority claimed from GBGB9819033.3A external-priority patent/GB9819033D0/en
Application filed filed Critical
Publication of JP2002523491A publication Critical patent/JP2002523491A/ja
Publication of JP2002523491A5 publication Critical patent/JP2002523491A5/ja
Pending legal-status Critical Current

Links

JP2000567508A 1998-09-01 1999-09-01 5−ht2bおよび/または5−ht2cレセプターリガンドとしてのインドール誘導体 Pending JP2002523491A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9819033.3A GB9819033D0 (en) 1998-09-01 1998-09-01 Chemical compounds VI
GB9819033.3 1998-09-01
PCT/GB1999/002879 WO2000012475A1 (en) 1998-09-01 1999-09-01 Indoline derivatives as 5-ht2b and/or 5-ht2c receptor ligands

Publications (2)

Publication Number Publication Date
JP2002523491A JP2002523491A (ja) 2002-07-30
JP2002523491A5 true JP2002523491A5 (enExample) 2006-11-02

Family

ID=10838165

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000567508A Pending JP2002523491A (ja) 1998-09-01 1999-09-01 5−ht2bおよび/または5−ht2cレセプターリガンドとしてのインドール誘導体

Country Status (7)

Country Link
US (1) US6380238B1 (enExample)
EP (1) EP1109784A1 (enExample)
JP (1) JP2002523491A (enExample)
AU (1) AU5637199A (enExample)
CA (1) CA2341525A1 (enExample)
GB (1) GB9819033D0 (enExample)
WO (1) WO2000012475A1 (enExample)

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US6465467B1 (en) 1999-05-21 2002-10-15 Biovitrum Ab Certain aryl-aliphatic and heteroaryl-aliphatic piperazinyl pyrazines and their use in the treatment of serotonin-related diseases
GB9918965D0 (en) 1999-08-11 1999-10-13 Cerebrus Ltd Chemical compounds xxi
WO2001040183A1 (en) * 1999-12-03 2001-06-07 Alcon Universal Ltd. 1-aminoalkyl-1h-indoles for treating glaucoma
US6806285B1 (en) 2000-03-17 2004-10-19 Alcon, Inc. 5-Hydroxyl indole derivatives for treating glaucoma
EP1263434A1 (en) * 2000-03-17 2002-12-11 Alcon, Inc Compounds with 5-ht 2 and 5-ht 1a agonist activity for treating glaucoma
US7012090B1 (en) 2000-03-17 2006-03-14 Alcon, Inc. Pyranoindoles for treating glaucoma
GB0019950D0 (en) * 2000-08-12 2000-09-27 Smithkline Beecham Plc Compounds
JP4204315B2 (ja) 2000-11-20 2009-01-07 ビオヴィトルム・アクチボラゲット(プブリクト) セロトニン5−ht2レセプターのアンタゴニストとしてのピペラジニルピラジン化合物
SE0004245D0 (sv) 2000-11-20 2000-11-20 Pharmacia Ab Novel compounds and their use
CA2432122A1 (en) 2000-12-20 2002-08-01 Bristol-Myers Squibb Pharma Company Aryl and aminoaryl substituted serotonin receptor agonist and antagonist ligands
CN1512879A (zh) 2001-06-01 2004-07-14 �Ƹ��� 新的芳氨基丙烷类似物及其用于治疗青光眼的用途
WO2002098350A2 (en) 2001-06-01 2002-12-12 Alcon, Inc. Pyranoindazoles and their use for the treatment of glaucoma
EP1392658A4 (en) 2001-06-01 2004-10-13 Alcon Inc NOVEL FUSED INDAZOLES AND INDOLES AND THEIR USE IN THE TREATMENT OF GLAUCOMES
US6884816B2 (en) 2001-08-31 2005-04-26 Alcon, Inc. Hydroxy substituted fused naphthyl-azoles and fused indeno-azoles and their use for the treatment of glaucoma
TW593302B (en) 2001-12-20 2004-06-21 Alcon Inc Novel benzodifuranimidazoline and benzofuranimidazoline derivatives and their use for the treatment of glaucoma
MXPA04012711A (es) 2002-06-19 2005-03-23 Biovitrum Ab Nuevos compuestos, su uso y preparacion.
KR20050033654A (ko) * 2002-08-30 2005-04-12 알콘, 인코퍼레이티드 치환된 5-크로만-5-일-에틸아민 화합물 및 녹내장의 치료용그의 용도
HRP20050396A2 (en) 2002-11-07 2005-06-30 Akzo Nobel N.V. Indoles useful in the treatment of androgen-receptor related diseases
EP1581209A4 (en) 2002-12-13 2009-03-11 Alcon Inc NEW BENZOPYRAN ANALOGUE AND ITS USE FOR THE TREATMENT OF GLAUKOM
CL2004000826A1 (es) 2003-04-25 2005-03-04 Pfizer Uso de un agonista para el receptor 5-ht2c para preparar un medicamento util en el tratamiento de la incontinencia urinaria provocada por estres, con la condicion de que el agonista no sea 1-[6-cloro-5-(trifluorometil)-2-piridinil]piperazina (org-129
GB0314967D0 (en) * 2003-06-26 2003-07-30 Hoffmann La Roche Piperazine derivatives
WO2005053688A1 (en) 2003-11-26 2005-06-16 Alcon, Inc. Substituted furo[2,3-g] indazoles for the treatment of glaucoma
US7338972B1 (en) 2003-12-15 2008-03-04 Alcon, Inc. Substituted 1-alkylamino-1H-indazoles for the treatment of glaucoma
WO2005058911A2 (en) 2003-12-15 2005-06-30 Alcon, Inc. Substituted [1,4]oxazino[2,3-g]indazoles for the treatment of glaucoma
US7129257B1 (en) 2003-12-15 2006-10-31 Alcon, Inc. Pyrazolo[3,4- e]benzoxazoles for the treatment of glaucoma
TW200602317A (en) 2004-04-23 2006-01-16 Akzo Nobel Nv Novel androgens
EP2248524A3 (en) 2004-08-25 2011-03-09 Takeda Pharmaceutical Company Limited Preventives/remedies for stress urinary incontinence and method of screening the same
US7425572B2 (en) 2004-12-08 2008-09-16 Alcon, Inc. Use of dioxindoindazoles and dioxoloindazoles for treating glaucoma
AP2007004144A0 (en) * 2005-03-31 2007-08-31 Pfizer Prod Inc Cyclopentapyridine and tetrahydroquinoline derivatives
CN101151249B (zh) * 2005-03-31 2011-04-06 辉瑞产品公司 环戊吡啶及四氢喹啉衍生物
WO2007132841A1 (ja) 2006-05-16 2007-11-22 Takeda Pharmaceutical Company Limited 縮合複素環化合物およびその用途
CA2657640A1 (en) * 2006-07-14 2008-01-24 Pfizer Products Inc. Tartrate salt of (7s)-7-[(5-fluoro-2-methyl-benzyl)oxy]-2-[(2r)-2-methylpiperazin-1-yl]-6,7-dihydro-5h-cyclopenta[b]pyridine
GB0715047D0 (en) * 2007-08-02 2007-09-12 Glaxo Group Ltd Novel Compounds
JP5520051B2 (ja) 2007-11-15 2014-06-11 武田薬品工業株式会社 縮合ピリジン誘導体およびその用途
KR101062376B1 (ko) 2008-04-10 2011-09-06 한국화학연구원 신규 인돌 카르복실산 비스피리딜 카르복사마이드 유도체,이의 제조방법 및 이를 유효성분으로 함유하는 조성물
WO2011071136A1 (ja) 2009-12-11 2011-06-16 アステラス製薬株式会社 線維筋痛症治療剤
WO2015066344A1 (en) 2013-11-01 2015-05-07 Arena Pharmaceuticals, Inc. 5-ht2c receptor agonists and compositions and methods of use
WO2017125932A1 (en) * 2016-01-21 2017-07-27 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd Indoline derivatives, compositions comprising them and uses thereof
JP7168456B2 (ja) * 2016-07-08 2022-11-09 アリゾナ ボード オブ リージェンツ オン ビハーフ オブ ザ ユニバーシティ オブ アリゾナ インドリン誘導体およびそれらを使用するならびに生産する方法
WO2018064465A1 (en) 2016-09-29 2018-04-05 The Regents Of The University Of California Compounds for increasing neural plasticity
WO2019131902A1 (ja) 2017-12-27 2019-07-04 武田薬品工業株式会社 腹圧性尿失禁および便失禁の治療薬
BR112021016620A2 (pt) 2019-02-27 2021-11-03 Univ California Azepino-indóis e outros heterociclos para o tratamento de distúrbios cerebrais
JP7636796B2 (ja) 2019-02-27 2025-02-27 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 脳障害を治療するためのn-置換インドール及び他の複素環化合物
CA3182182A1 (en) * 2020-06-10 2021-12-16 Florence Wagner Isotryptamine psychoplastogens and uses thereof
CA3239565A1 (en) 2021-12-15 2023-06-22 Delix Therapeutics, Inc. Phenoxy and benzyloxy substituted psychoplastogens and uses thereof
IL316416A (en) * 2022-04-19 2024-12-01 Mindset Pharma Inc Indoline derivatives as estrogenic agents for the treatment of disorders

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW270114B (enExample) * 1993-10-22 1996-02-11 Hoffmann La Roche
WO1995032967A1 (en) * 1994-05-28 1995-12-07 Smithkline Beecham Plc Amide derivatives having 5ht1d-antagonist activity
FR2742047B1 (fr) 1995-12-06 1998-01-16 Oreal Compositions de teinture des fibres keratiniques contenant des derives n-substitues de la 4-hydroxy indoline, nouveaux derives, leur procede de synthese, leur utilisation pour la teinture, et procede de teinture

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