JP2012097115A5 - - Google Patents
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- Publication number
- JP2012097115A5 JP2012097115A5 JP2012014419A JP2012014419A JP2012097115A5 JP 2012097115 A5 JP2012097115 A5 JP 2012097115A5 JP 2012014419 A JP2012014419 A JP 2012014419A JP 2012014419 A JP2012014419 A JP 2012014419A JP 2012097115 A5 JP2012097115 A5 JP 2012097115A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- substituted
- pyridyl
- benzyl
- propyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 7
- 150000001875 compounds Chemical class 0.000 claims 5
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims 4
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 4
- -1 methoxy, ethoxy Chemical group 0.000 claims 4
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 claims 4
- 125000004076 pyridyl group Chemical group 0.000 claims 4
- 239000003814 drug Substances 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 claims 2
- 125000004200 2-methoxyethyl group Chemical group [H]C([H])([H])OC([H])([H])C([H])([H])* 0.000 claims 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims 2
- 101100407341 Drosophila melanogaster Pde9 gene Proteins 0.000 claims 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 2
- 239000000460 chlorine Substances 0.000 claims 2
- 229910052801 chlorine Inorganic materials 0.000 claims 2
- 239000001257 hydrogen Substances 0.000 claims 2
- 229910052739 hydrogen Inorganic materials 0.000 claims 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 2
- 230000002401 inhibitory effect Effects 0.000 claims 2
- 230000008447 perception Effects 0.000 claims 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims 2
- OJWYYSVOSNWCCE-UHFFFAOYSA-N 2-methoxyethyl hypofluorite Chemical group COCCOF OJWYYSVOSNWCCE-UHFFFAOYSA-N 0.000 claims 1
- 208000024827 Alzheimer disease Diseases 0.000 claims 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 claims 1
- 125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 125000004672 ethylcarbonyl group Chemical group [H]C([H])([H])C([H])([H])C(*)=O 0.000 claims 1
- 229910052731 fluorine Inorganic materials 0.000 claims 1
- 239000011737 fluorine Substances 0.000 claims 1
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 claims 1
- 125000000623 heterocyclic group Chemical group 0.000 claims 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 claims 1
- 125000004674 methylcarbonyl group Chemical group CC(=O)* 0.000 claims 1
- 125000002757 morpholinyl group Chemical group 0.000 claims 1
- 229910052757 nitrogen Inorganic materials 0.000 claims 1
- 125000004433 nitrogen atom Chemical group N* 0.000 claims 1
- 125000004430 oxygen atom Chemical group O* 0.000 claims 1
- 125000004193 piperazinyl group Chemical group 0.000 claims 1
- 125000003386 piperidinyl group Chemical group 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 125000004673 propylcarbonyl group Chemical group 0.000 claims 1
- 125000000719 pyrrolidinyl group Chemical group 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 125000001424 substituent group Chemical group 0.000 claims 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 claims 1
- 125000001544 thienyl group Chemical group 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102004001873A DE102004001873A1 (de) | 2004-01-14 | 2004-01-14 | Cyanopyrimidinone |
| DE102004001873.1 | 2004-01-14 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006548184A Division JP4951349B2 (ja) | 2004-01-14 | 2004-12-31 | 知覚力、集中力、学習力および／または記憶力の改善のために使用される６−アミノ−５−シアノ−ピリミジン−４−オン化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012097115A JP2012097115A (ja) | 2012-05-24 |
| JP2012097115A5 true JP2012097115A5 (enExample) | 2012-07-12 |
| JP5457476B2 JP5457476B2 (ja) | 2014-04-02 |
Family
ID=34778055
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006548184A Expired - Lifetime JP4951349B2 (ja) | 2004-01-14 | 2004-12-31 | 知覚力、集中力、学習力および／または記憶力の改善のために使用される６−アミノ−５−シアノ−ピリミジン−４−オン化合物 |
| JP2012014419A Expired - Lifetime JP5457476B2 (ja) | 2004-01-14 | 2012-01-26 | 知覚力、集中力、学習力および／または記憶力の改善のために使用される６−アミノ−５−シアノ−ピリミジン−４−オン化合物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006548184A Expired - Lifetime JP4951349B2 (ja) | 2004-01-14 | 2004-12-31 | 知覚力、集中力、学習力および／または記憶力の改善のために使用される６−アミノ−５−シアノ−ピリミジン−４−オン化合物 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US8088769B2 (enExample) |
| EP (1) | EP1709009B1 (enExample) |
| JP (2) | JP4951349B2 (enExample) |
| KR (1) | KR20070015372A (enExample) |
| CN (2) | CN1926117B (enExample) |
| AU (1) | AU2004313696B2 (enExample) |
| BR (1) | BRPI0418407A (enExample) |
| CA (1) | CA2553200A1 (enExample) |
| DE (1) | DE102004001873A1 (enExample) |
| IL (1) | IL176780A0 (enExample) |
| NZ (1) | NZ548470A (enExample) |
| RU (1) | RU2006129164A (enExample) |
| WO (1) | WO2005068436A1 (enExample) |
| ZA (1) | ZA200605781B (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10238724A1 (de) | 2002-08-23 | 2004-03-04 | Bayer Ag | Alkyl-substituierte Pyrazolpyrimidine |
| DE10238723A1 (de) * | 2002-08-23 | 2004-03-11 | Bayer Ag | Phenyl-substituierte Pyrazolyprimidine |
| DE10238722A1 (de) * | 2002-08-23 | 2004-03-11 | Bayer Ag | Selektive Phosphodiesterase 9A-Inhibitoren als Arzneimittel zur Verbesserung kognitiver Prozesse |
| DE10320785A1 (de) * | 2003-05-09 | 2004-11-25 | Bayer Healthcare Ag | 6-Arylmethyl-substituierte Pyrazolopyrimidine |
| US8044060B2 (en) | 2003-05-09 | 2011-10-25 | Boehringer Ingelheim International Gmbh | 6-cyclylmethyl- and 6-alkylmethyl pyrazolo[3,4-D]pyrimidines, methods for their preparation and methods for their use to treat impairments of perception, concentration learning and/or memory |
| DE102004001873A1 (de) * | 2004-01-14 | 2005-09-29 | Bayer Healthcare Ag | Cyanopyrimidinone |
| EP2217602B1 (en) | 2007-11-30 | 2018-08-29 | Boehringer Ingelheim International GmbH | 1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one derivatives and their use as pde9a modulators for the treatment of cns disorders |
| UA105362C2 (en) | 2008-04-02 | 2014-05-12 | Бьорингер Ингельхайм Интернациональ Гмбх | 1-heterocyclyl-1, 5-dihydro-pyrazolo [3, 4-d] pyrimidin-4-one derivatives and their use as pde9a modulators |
| PE20110383A1 (es) | 2008-09-08 | 2011-07-15 | Boehringer Ingelheim Int | Pirazolopirimidinonas como inhibidores de la fosfodiesterasa 9a (pde9a) |
| CA2757231A1 (en) | 2009-03-31 | 2010-10-07 | Boehringer Ingelheim International Gmbh | 1-heterocyclyl-1,5-dihydro-pyrazolo [3,4-d] pyrimidin-4-one derivatives and their use as pde9a modulators |
| AR077859A1 (es) * | 2009-08-12 | 2011-09-28 | Boehringer Ingelheim Int | Compuestos para el tratamiento de trastornos del snc |
| CA2807687C (en) | 2010-08-12 | 2019-01-08 | Boehringer Ingelheim International Gmbh | 6-cycloalkyl-1, 5-dihydro-pyrazolo [3,4-d] pyrimidin-4-one derivatives and their use as pde9a inhibitors |
| US8809345B2 (en) | 2011-02-15 | 2014-08-19 | Boehringer Ingelheim International Gmbh | 6-cycloalkyl-pyrazolopyrimidinones for the treatment of CNS disorders |
| US9340504B2 (en) * | 2013-11-21 | 2016-05-17 | Purdue Pharma L.P. | Pyridine and piperidine derivatives as novel sodium channel blockers |
Family Cites Families (74)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3165520A (en) | 1965-01-12 | Certificate of correction | ||
| US3169965A (en) | 1965-02-16 | New x-mercapto-pyrazolo | ||
| CH396923A (de) | 1960-05-11 | 1965-08-15 | Ciba Geigy | Verfahren zur Herstellung von 4-Mercapto-pyrazolo(3,4-d)pyrimidinen |
| DE1161281B (de) | 1960-05-11 | 1964-01-16 | Ciba Aktiengesellschaft, Basel (Schweiz) | Verfahren zur Herstellung von 1-Alkyl-6-aralkyl-pyrazoloÄ3,4-dÜ-pyrimidinen. |
| DE1149013B (de) | 1960-05-11 | 1963-05-22 | Ciba Geigy | Verfahren zur Herstellung von 4-Oxo-4, 5-dihydro-pyrazolo-[3, 4-d]Pyrimidinen |
| CH398626A (de) | 1960-05-11 | 1966-03-15 | Ciba Geigy | Verfahren zur Herstellung neuer Pyrazolopyrimidine |
| DE1153023B (de) | 1960-05-11 | 1963-08-22 | Ciba Geigy | Verfahren zur Herstellung von 4-Hydroxy-pyrazolo[3,4-d] pyrimidinen |
| GB973361A (en) | 1960-05-11 | 1964-10-28 | Ciba Ltd | Pyrazolo-pyrimidines and process for their manufacture |
| CH396926A (de) | 1960-05-11 | 1965-08-15 | Ciba Geigy | Verfahren zur Herstellung neuer Pyrazolopyrimidine |
| ES267249A1 (es) | 1960-05-11 | 1961-11-01 | Ciba Geigy | Procedimiento para la obtencion de pirazolo-pirimidinas nuevas |
| CH396925A (de) | 1960-05-11 | 1965-08-15 | Ciba Geigy | Verfahren zur Herstellung neuer Pyrazolopyrimidine |
| DE1156415B (de) | 1960-05-11 | 1963-10-31 | Ciba Geigy | Verfahren zur Herstellung von 1-Isopropyl-4-hydroxy-pyrazolo [3, 4-d]-pyrimidinen |
| DE1147234B (de) | 1960-05-11 | 1963-04-18 | Ciba Geigy | Verfahren zur Herstellung von 1-Isopropyl-4-hydroxy-6-benzyl-pyrazolo[3, 4-d]pyrimidin |
| CH396927A (de) | 1960-05-11 | 1965-08-15 | Ciba Geigy | Verfahren zur Herstellung neuer Pyrazolopyrimidine |
| GB937723A (en) | 1960-05-11 | 1963-09-25 | Ciba Ltd | Pyrazolo-pyrimidines and process for their manufacture |
| CH396924A (de) | 1960-05-11 | 1965-08-15 | Ciba Geigy | Verfahren zur Herstellung von 4-Mercapto-pyrazolo(3,4-d)pyrimidinen |
| US3732225A (en) | 1970-07-23 | 1973-05-08 | Squibb & Sons Inc | Pyrazolo(3,4-d)pyrimidine derivatives |
| US3847908A (en) | 1973-03-05 | 1974-11-12 | Squibb & Sons Inc | 6-styrylpyrazolo(3,4-d)pyrimidinones and pyrimidines |
| US4505910A (en) * | 1983-06-30 | 1985-03-19 | American Home Products Corporation | Amino-pyrimidine derivatives, compositions and use |
| GR82004B (enExample) | 1983-06-30 | 1984-12-12 | American Home Prod | |
| US6211158B1 (en) | 1987-04-10 | 2001-04-03 | Roche Diagnostics Gmbh | Desazapurine-nucleotide derivatives, processes for the preparation thereof, pharmaceutical compositions containing them and the use thereof for nucleic acid sequencing and as antiviral agents |
| DE3739366A1 (de) | 1987-04-10 | 1988-10-27 | Boehringer Mannheim Gmbh | Desaza-purin-nucleosid-derivate, verfahren zu deren herstellung sowie deren verwendung bei der nucleinsaeure-sequenzierung sowie als antivirale mittel |
| US5041449A (en) | 1988-04-11 | 1991-08-20 | Iaf Biochem International, Inc. | 4-(nucleoside base)-substituted-1,3-dioxolanes useful for treatment of retroviral infections |
| US6350753B1 (en) | 1988-04-11 | 2002-02-26 | Biochem Pharma Inc. | 2-Substituted-4-substituted-1,3-dioxolanes and use thereof |
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| US7119202B1 (en) | 1989-02-08 | 2006-10-10 | Glaxo Wellcome Inc. | Substituted-1,3-oxathiolanes and substituted-1,3-dioxolanes with antiviral properties |
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| JP2619710B2 (ja) | 1989-02-27 | 1997-06-11 | 日本製紙 株式会社 | ２′，３′−ジデオキシプリンヌクレオシド類の製造方法 |
| US5002949A (en) | 1990-05-01 | 1991-03-26 | American Home Products Corporation | 5-substituted-6-aminopyrimidine derivatives |
| FI933303L (fi) | 1991-01-23 | 1993-08-31 | Gensia Inc | Adenosinkinasinhibitorer |
| US5294612A (en) | 1992-03-30 | 1994-03-15 | Sterling Winthrop Inc. | 6-heterocyclyl pyrazolo [3,4-d]pyrimidin-4-ones and compositions and method of use thereof |
| US5256668A (en) | 1993-03-17 | 1993-10-26 | American Home Products Corporation | Aminopyrimidine derivatives as antiviral agents for respiratory syncytial virus |
| ATE177430T1 (de) | 1993-05-12 | 1999-03-15 | Novartis Erfind Verwalt Gmbh | Nukleoside und oligonukleotide mit 2'- ethergruppen |
| WO1995010506A1 (en) * | 1993-10-12 | 1995-04-20 | The Du Pont Merck Pharmaceutical Company | 1n-alkyl-n-arylpyrimidinamines and derivatives thereof |
| EP0679657B1 (de) | 1994-04-27 | 2003-07-09 | Novartis AG | Nukleoside und Oligonukleotide mit 2'-Ethergruppen |
| GB9423910D0 (en) | 1994-11-26 | 1995-01-11 | Pfizer Ltd | Therapeutic agents |
| US5656629A (en) | 1995-03-10 | 1997-08-12 | Sanofi Winthrop, Inc. | 6-substituted pyrazolo (3,4-d)pyrimidin-4-ones and compositions and methods of use thereof |
| US6509320B1 (en) | 1996-10-16 | 2003-01-21 | Icn Pharmaceuticals, Inc. | Purine L-nucleosides, analogs and uses thereof |
| HUP0001186A3 (en) | 1996-10-16 | 2002-04-29 | Icn Pharmaceuticals Inc Costa | Purine l-nucleosides,analogs and pharmaceutical compositions thereof |
| DE19709877A1 (de) | 1997-03-11 | 1998-09-17 | Bayer Ag | 1,5-Dihydro-pyrazolo[3,4-d]-pyrimidinon-derivate |
| DE19838705A1 (de) | 1998-08-26 | 2000-03-02 | Bayer Ag | Neue Dihydro-(1,2,3)-triazolo-[4,5-d]pyrimidin-7-one |
| AR023052A1 (es) * | 1998-09-25 | 2002-09-04 | Mitsuharu Yoshimura Milton | Derivados de pirimidona |
| GB9823103D0 (en) | 1998-10-23 | 1998-12-16 | Pfizer Ltd | Pharmaceutically active compounds |
| US6225315B1 (en) | 1998-11-30 | 2001-05-01 | Pfizer Inc | Method of treating nitrate-induced tolerance |
| US6100037A (en) | 1999-01-07 | 2000-08-08 | Incyte Pharmaceuticals, Inc. | Human cyclic nucleotide PDEs |
| US6369222B1 (en) | 2000-07-18 | 2002-04-09 | Hoffmann-La Roche Inc. | mGluR antagonists and a method for their synthesis |
| JP2004505054A (ja) | 2000-08-01 | 2004-02-19 | バイエル アクチェンゲゼルシャフト | 知覚を改善する医薬品としての選択的ｐｄｅ２インヒビター |
| GB0100621D0 (en) | 2001-01-10 | 2001-02-21 | Vernalis Res Ltd | Chemical compounds VI |
| DE10108752A1 (de) | 2001-02-23 | 2002-09-05 | Bayer Ag | Neue Substituierte Imidazotriazinone |
| US20040185459A1 (en) | 2001-04-18 | 2004-09-23 | Masami Otsuka | Hybridization probe |
| DK1397351T3 (da) * | 2001-06-01 | 2010-01-18 | Hoffmann La Roche | Pyrimidin-, triazin- og pyrazinderivater som glutamatreceptorer |
| BR0210391A (pt) | 2001-06-12 | 2004-06-15 | Elan Pharm Inc | Composto, métodos de tratar um paciente que tenha ou de prevenir um paciente de contrair uma doença ou condição e de preparar um composto, e, uso de um composto |
| JP2004536933A (ja) | 2001-07-25 | 2004-12-09 | ピーピージー インダストリーズ オハイオ， インコーポレイテッド | 高屈折率光学樹脂組成物 |
| HN2002000317A (es) | 2001-11-02 | 2003-05-21 | Pfizer | Inhibidores de pde9 para tratamiento de trastornos cardiovasculares |
| SE0103795D0 (sv) * | 2001-11-02 | 2001-11-02 | Astrazeneca Ab | Compounds and method for the treatment of överactive bladder |
| DE10156249A1 (de) | 2001-11-15 | 2003-05-28 | Bayer Ag | Regulation der cGMP-spezifischen Phosphodiesterase 9A |
| DE10219435A1 (de) | 2002-05-02 | 2003-11-13 | Bayer Cropscience Ag | Substituierte Pyrazolo-pyrimidin-4-one |
| DE10238723A1 (de) | 2002-08-23 | 2004-03-11 | Bayer Ag | Phenyl-substituierte Pyrazolyprimidine |
| DE10238722A1 (de) | 2002-08-23 | 2004-03-11 | Bayer Ag | Selektive Phosphodiesterase 9A-Inhibitoren als Arzneimittel zur Verbesserung kognitiver Prozesse |
| DE10238724A1 (de) | 2002-08-23 | 2004-03-04 | Bayer Ag | Alkyl-substituierte Pyrazolpyrimidine |
| ATE368666T1 (de) | 2003-03-18 | 2007-08-15 | Jordanian Pharmaceutical Mfg | Pyrazolopyrimidinone und ihre verwendung als pde inhibitoren |
| US20040220186A1 (en) | 2003-04-30 | 2004-11-04 | Pfizer Inc. | PDE9 inhibitors for treating type 2 diabetes,metabolic syndrome, and cardiovascular disease |
| US8044060B2 (en) | 2003-05-09 | 2011-10-25 | Boehringer Ingelheim International Gmbh | 6-cyclylmethyl- and 6-alkylmethyl pyrazolo[3,4-D]pyrimidines, methods for their preparation and methods for their use to treat impairments of perception, concentration learning and/or memory |
| DE10320785A1 (de) | 2003-05-09 | 2004-11-25 | Bayer Healthcare Ag | 6-Arylmethyl-substituierte Pyrazolopyrimidine |
| EP1631295B1 (en) | 2003-06-06 | 2010-03-03 | Arexis AB | Use of condensed heterocyclic compounds as scce inhibitors for the treatment of skin diseases |
| DE10328479A1 (de) | 2003-06-25 | 2005-01-13 | Bayer Ag | 6-Arylamino-5-cyano-4-pyrimidinone |
| DE102004001873A1 (de) * | 2004-01-14 | 2005-09-29 | Bayer Healthcare Ag | Cyanopyrimidinone |
| JP2006201272A (ja) | 2005-01-18 | 2006-08-03 | Tamura Seisakusho Co Ltd | Ｉｐ電話端末及びカラオケ配信サーバシステム |
| EP2217602B1 (en) | 2007-11-30 | 2018-08-29 | Boehringer Ingelheim International GmbH | 1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one derivatives and their use as pde9a modulators for the treatment of cns disorders |
| UA105362C2 (en) | 2008-04-02 | 2014-05-12 | Бьорингер Ингельхайм Интернациональ Гмбх | 1-heterocyclyl-1, 5-dihydro-pyrazolo [3, 4-d] pyrimidin-4-one derivatives and their use as pde9a modulators |
| CA2757231A1 (en) | 2009-03-31 | 2010-10-07 | Boehringer Ingelheim International Gmbh | 1-heterocyclyl-1,5-dihydro-pyrazolo [3,4-d] pyrimidin-4-one derivatives and their use as pde9a modulators |
-
2004
- 2004-01-14 DE DE102004001873A patent/DE102004001873A1/de not_active Withdrawn
- 2004-12-31 KR KR1020067016336A patent/KR20070015372A/ko not_active Ceased
- 2004-12-31 AU AU2004313696A patent/AU2004313696B2/en not_active Expired - Fee Related
- 2004-12-31 JP JP2006548184A patent/JP4951349B2/ja not_active Expired - Lifetime
- 2004-12-31 CA CA002553200A patent/CA2553200A1/en not_active Abandoned
- 2004-12-31 US US10/586,501 patent/US8088769B2/en active Active
- 2004-12-31 BR BRPI0418407-6A patent/BRPI0418407A/pt not_active IP Right Cessation
- 2004-12-31 RU RU2006129164/04A patent/RU2006129164A/ru not_active Application Discontinuation
- 2004-12-31 CN CN2004800424446A patent/CN1926117B/zh not_active Expired - Fee Related
- 2004-12-31 WO PCT/EP2004/014872 patent/WO2005068436A1/de not_active Ceased
- 2004-12-31 NZ NZ548470A patent/NZ548470A/en unknown
- 2004-12-31 CN CN2011102634188A patent/CN102382063A/zh active Pending
- 2004-12-31 EP EP04804457.2A patent/EP1709009B1/de not_active Expired - Lifetime
-
2006
- 2006-07-11 IL IL176780A patent/IL176780A0/en unknown
- 2006-07-13 ZA ZA200605781A patent/ZA200605781B/en unknown
-
2011
- 2011-05-02 US US13/099,064 patent/US8431573B2/en not_active Expired - Lifetime
-
2012
- 2012-01-26 JP JP2012014419A patent/JP5457476B2/ja not_active Expired - Lifetime
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