|
US2642438A
(en)
|
1949-07-15 |
1953-06-16 |
Hoffmann La Roche |
Pyridindoles and method of manufacture
|
|
GB721171A
(en)
*
|
1951-04-30 |
1954-12-29 |
Bayer Ag |
Derivatives of ª‰- and ª†- carbolines
|
|
JPS3920857B1
(enExample)
|
1962-05-17 |
1964-09-24 |
|
|
|
JPS412713B1
(enExample)
|
1963-08-30 |
1966-02-21 |
|
|
|
DE3240511A1
(de)
|
1982-10-29 |
1984-05-03 |
Schering AG, 1000 Berlin und 4709 Bergkamen |
Verfahren zur herstellung von ss-carbolinderivaten
|
|
US4754038A
(en)
*
|
1987-02-26 |
1988-06-28 |
American Home Products Corporation |
Carboline histamine H1 antagonists
|
|
US5817756A
(en)
|
1993-09-09 |
1998-10-06 |
Scios Inc. |
Pseudo- and non-peptide bradykinin receptor antagonists
|
|
JPH11500100A
(ja)
|
1993-09-09 |
1999-01-06 |
サイオス ノバ インコーポレイテッド |
偽ペプチドおよび非ペプチドブラジキニンレセプターアンタゴニスト
|
|
US5631265A
(en)
|
1994-03-11 |
1997-05-20 |
Eli Lilly And Company |
8-substituted tetrahydro-beta-carbolines
|
|
US5688807A
(en)
|
1994-03-11 |
1997-11-18 |
Eli Lilly And Company |
Method for treating 5HT2B receptor related conditions
|
|
HUT75522A
(en)
|
1994-03-11 |
1997-05-28 |
Lilly Co Eli |
Indole-, pyrido-indole-, indolo-quinoline- and benzo-pyrido-indole-derivatives, method for treating 5ht2b receptor related conditions, pharmaceutical compositions containing them
|
|
EP0823909B1
(en)
|
1995-05-05 |
2002-09-11 |
British Technology Group Inter-Corporate Licensing Limited |
Novel heterocyclic chemistry
|
|
RU2140417C1
(ru)
|
1995-10-17 |
1999-10-27 |
Институт физиологически активных веществ РАН |
Производные гидрированных пиридо(4,3-b)индолов, способы их получения, фармацевтическая композиция и способ лечения
|
|
RU2106864C1
(ru)
|
1995-10-23 |
1998-03-20 |
Николай Серафимович Зефиров |
Средство для лечения болезни альцгеймера
|
|
GB9604996D0
(en)
*
|
1996-03-08 |
1996-05-08 |
Black James Foundation |
Benzodiazonine derivatives
|
|
JP2000508302A
(ja)
|
1996-04-04 |
2000-07-04 |
エフ．ホフマン―ラ ロッシュ エイジー |
抗転移剤としてのテトラヒドロ―β―カルボリン誘導体の使用
|
|
FR2771095B1
(fr)
|
1997-11-14 |
1999-12-17 |
Adir |
Nouveaux inhibiteurs de metalloproteases, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
|
JP2001522884A
(ja)
|
1997-11-14 |
2001-11-20 |
イーライ・リリー・アンド・カンパニー |
アルツハイマー病の処置方法
|
|
CA2316388C
(en)
|
1997-12-25 |
2009-09-08 |
Meiji Seika Kaisha Ltd. |
Tetrahydrobenzindole derivative
|
|
FR2796644B1
(fr)
|
1999-07-23 |
2001-09-07 |
Adir |
Nouveaux derives de beta-carboline, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
|
UA74826C2
(en)
|
2000-05-17 |
2006-02-15 |
Ortho Mcneil Pharm Inc |
?-carboline derivatives as phosphodiesterase inhibitors
|
|
US20060235012A1
(en)
|
2003-06-16 |
2006-10-19 |
Chroma Therapeutics Limited |
Carboline and betacarboline derivatives for use as hdac enzyme inhibitors
|
|
JP4671123B2
(ja)
|
2003-06-23 |
2011-04-13 |
小野薬品工業株式会社 |
新規三環性複素環化合物
|
|
WO2005031301A2
(en)
*
|
2003-07-10 |
2005-04-07 |
Parallax Biosystems, Inc. |
Raman signature probes and their use in the detection and imaging of molecular processes and structures
|
|
US20070179174A1
(en)
|
2003-12-08 |
2007-08-02 |
Bachurin Sergei O |
Methods and compositions for slowing aging
|
|
RU2283108C2
(ru)
|
2003-12-08 |
2006-09-10 |
Сергей Олегович Бачурин |
ГЕРОПРОТЕКТОР НА ОСНОВЕ ГИДРИРОВАННЫХ ПИРИДО(4,3-b) ИНДОЛОВ (ВАРИАНТЫ), ФАРМАКОЛОГИЧЕСКОЕ СРЕДСТВО НА ЕГО ОСНОВЕ И СПОСОБ ЕГО ПРИМЕНЕНИЯ
|
|
EP1714961B1
(en)
|
2004-02-12 |
2015-12-09 |
Mitsubishi Tanabe Pharma Corporation |
Indazole compound and pharmaceutical use thereof
|
|
US8076352B2
(en)
|
2004-03-15 |
2011-12-13 |
Ptc Therapeutics, Inc. |
Administration of carboline derivatives useful in the treatment of cancer and other diseases
|
|
WO2006011750A1
(en)
|
2004-07-27 |
2006-02-02 |
C & C Research Laboratories |
Tetrahydro-beta-carbolinone derivatives and process for preparing the same
|
|
JP2008530136A
(ja)
|
2005-02-14 |
2008-08-07 |
ミイカナ セラピューティクス インコーポレイテッド |
ヒストンデアセチラーゼの阻害剤として有用な縮合複素環化合物
|
|
EP1902044A1
(en)
*
|
2005-07-07 |
2008-03-26 |
Bio Medisinsk Innovasjon AS |
5-htx modulators
|
|
EP1747779A1
(en)
|
2005-07-28 |
2007-01-31 |
Laboratorios Del Dr. Esteve, S.A. |
Tetrahydro-b-carbolin-sulfonamide derivatives as 5-HT6 ligands
|
|
CA2624731A1
(en)
|
2005-10-04 |
2007-04-12 |
Medivation, Inc. |
Hydrogenated pyrido-indole compounds for the treatment of huntington's disease
|
|
RU2338537C2
(ru)
|
2006-01-25 |
2008-11-20 |
Сергей Олегович Бачурин |
СРЕДСТВО ДЛЯ ЛЕЧЕНИЯ ШИЗОФРЕНИИ НА ОСНОВЕ ГИДРИРОВАННЫХ ПИРИДО(4,3-b)ИНДОЛОВ (ВАРИАНТЫ), ФАРМАКОЛОГИЧЕСКОЕ СРЕДСТВО НА ЕГО ОСНОВЕ И СПОСОБ ЕГО ПРИМЕНЕНИЯ
|
|
US20090247546A1
(en)
*
|
2006-02-28 |
2009-10-01 |
Boehringer Ingelheim International Gmbh |
Treatment of Prevention of Valvular Heart Disease with Flibanserin
|
|
JP2010504337A
(ja)
|
2006-09-20 |
2010-02-12 |
メディベイション ニューロロジー， インコーポレイテッド |
イヌの認知機能障害症候群の治療のためのディメボン（ｄｉｍｅｂｏｎ）などの水素化ピリド［４，３−ｂ］インドール
|
|
US20100099700A1
(en)
|
2006-09-20 |
2010-04-22 |
David Hung |
Hydrogenated pyrido (4,3-b) indoles for treating amyotrophic lateral sclerosis (als)
|
|
ATE549021T1
(de)
|
2006-10-27 |
2012-03-15 |
Medivation Neurology Inc |
Kombinationstherapien zur behandlung von morbus alzheimer mit dimebon und donepezil
|
|
RU2329044C1
(ru)
|
2006-11-16 |
2008-07-20 |
Андрей Александрович Иващенко |
Лиганды 5-ht6 рецепторов, фармацевтическая композиция, способ ее получения и лекарственное средство
|
|
RU2334514C1
(ru)
|
2006-12-01 |
2008-09-27 |
Институт физиологически активных веществ Российской Академии наук |
СРЕДСТВО ДЛЯ УЛУЧШЕНИЯ КОГНИТИВНЫХ ФУНКЦИЙ И ПАМЯТИ НА ОСНОВЕ ГИДРИРОВАННЫХ ПИРИДО (4,3-b) ИНДОЛОВ (ВАРИАНТЫ), ФАРМАКОЛОГИЧЕСКОЕ СРЕДСТВО НА ЕГО ОСНОВЕ И СПОСОБ ЕГО ПРИМЕНЕНИЯ
|
|
RU2340342C2
(ru)
|
2006-12-07 |
2008-12-10 |
Сергей Олегович Бачурин |
СРЕДСТВО ДЛЯ ЛЕЧЕНИЯ ОСТРЫХ И ХРОНИЧЕСКИХ НАРУШЕНИЙ МОЗГОВОГО КРОВООБРАЩЕНИЯ, В ТОМ ЧИСЛЕ ИНСУЛЬТА, НА ОСНОВЕ ГИДРИРОВАННЫХ ПИРИДО[4,3-b]ИНДОЛОВ (ВАРИАНТЫ), ФАРМАКОЛОГИЧЕСКОЕ СРЕДСТВО НА ЕГО ОСНОВЕ И СПОСОБ ЕГО ПРИМЕНЕНИЯ
|
|
WO2008096791A1
(ja)
|
2007-02-07 |
2008-08-14 |
Astellas Pharma Inc. |
アシルグアニジン誘導体
|
|
DE102007009264A1
(de)
|
2007-02-26 |
2008-08-28 |
Ellneuroxx Ltd. |
9-Alkyl-ß-Carboline zur Behandlung von neurodegenerativen Erkrankungen
|
|
RU2338745C1
(ru)
|
2007-03-21 |
2008-11-20 |
Андрей Александрович Иващенко |
ЗАМЕЩЕННЫЕ 2,3,4,5-ТЕТРАГИДРО-1Н-ПИРИДО[4,3-b]ИНДОЛЫ, СПОСОБЫ ИХ ПОЛУЧЕНИЯ И ПРИМЕНЕНИЯ
|
|
RU2339637C1
(ru)
|
2007-04-05 |
2008-11-27 |
Андрей Александрович Иващенко |
Блокаторы гистаминного рецептора для фармацевтических композиций, обладающих противоаллергическим и аутоиммунным действием
|
|
KR20090130105A
(ko)
|
2007-04-05 |
2009-12-17 |
알라 캠, 엘엘씨 |
치환된 2,3,4,5-테트라히드로-1ｈ-피리도［4,3-ｂ］ 인돌, 그 제조방법 및 용도
|
|
CA2688327A1
(en)
|
2007-05-25 |
2008-12-04 |
Medivation Neurology, Inc. |
Methods and compositions for stimulating cells
|
|
RU2338533C1
(ru)
|
2007-06-28 |
2008-11-20 |
Сергей Олегович Бачурин |
СРЕДСТВО, ОБЛАДАЮЩЕЕ АНКСИОЛИТИЧЕСКИМ ДЕЙСТВИЕМ, НА ОСНОВЕ ГИДРИРОВАННЫХ ПИРИДО(4,3-b)ИНДОЛОВ (ВАРИАНТЫ), ФАРМАКОЛОГИЧЕСКОЕ СРЕДСТВО НА ЕГО ОСНОВЕ И СПОСОБ ЕГО ПРИМЕНЕНИЯ
|
|
WO2009017836A1
(en)
|
2007-08-01 |
2009-02-05 |
Medivation Neurology, Inc. |
Methods and compositions for treating schizophrenia using antipsychotic combination therapy
|
|
WO2009039420A1
(en)
|
2007-09-21 |
2009-03-26 |
Medivation Neurology, Inc. |
Methods and compositions for treating neuronal death mediated ocular diseases
|
|
RU2007139634A
(ru)
|
2007-10-25 |
2009-04-27 |
Сергей Олегович Бачурин (RU) |
Новые тиазол-, триазол- или оксадиазол-содержащие тетрациклические соединения
|
|
JP5366211B2
(ja)
|
2007-12-18 |
2013-12-11 |
国立大学法人富山大学 |
アルドース還元酵素阻害活性を有する縮合三環化合物
|
|
EP2236511A4
(en)
|
2007-12-21 |
2011-04-13 |
Alla Chem Llc |
LIGANDS OF ALPHA ADRENOCEPTORS AND OF DOPAMINE, HISTAMIN, IMIDAZOLIN AND SEROTONIN RECEPTORS AND THEIR APPLICATION THEREOF
|
|
RU2544856C2
(ru)
|
2008-01-25 |
2015-03-20 |
Сергей Олегович Бачурин |
НОВЫЕ ПРОИЗВОДНЫЕ 2,3,4,5-ТЕТРАГИДРО-1-ПИРИДО[4,3-b]ИНДОЛА И СПОСОБЫ ИХ ПРИМЕНЕНИЯ
|
|
WO2009111540A1
(en)
|
2008-03-04 |
2009-09-11 |
Medivation Neurology, Inc. |
Methods for preparing pyridylethyl-substituted carbolines
|
|
ES2602577T3
(es)
|
2008-03-11 |
2017-02-21 |
Incyte Holdings Corporation |
Derivados de azetidina y ciclobutano como inhibidores de JAK
|
|
EP2280968A2
(en)
|
2008-03-24 |
2011-02-09 |
Medivation Technologies, Inc. |
Pyrido [3, 4-b]indoles and methods of use
|
|
WO2009120720A1
(en)
|
2008-03-24 |
2009-10-01 |
Medivation Technologies,Inc. |
Bridged heterocyclic compounds and methods of use
|
|
US8293758B2
(en)
|
2008-03-27 |
2012-10-23 |
Grunenthal Gmbh |
Substituted spirocyclic cyclohexane derivatives
|
|
WO2009135091A1
(en)
|
2008-04-30 |
2009-11-05 |
Medivation Technologies, Inc. |
Use of asenapine and related compounds for the treatment of neuronal or non-neuronal diseases or conditions
|
|
UY31831A
(es)
|
2008-05-20 |
2010-01-05 |
Astrazeneca Ab |
Derivados de indazoles sustituidos con fenilo o piridinilo
|
|
US20100029706A1
(en)
|
2008-07-30 |
2010-02-04 |
Edison Parmaceuticals, Inc. a Delaware Corporation |
HYDROGENATED PYRIDO[4,3-b]INDOLES FOR THE TREATMENT OF OXIDATIVE STRESS
|
|
AU2009308708B2
(en)
|
2008-10-31 |
2015-11-19 |
Medivation Technologies, Inc. |
Azepino [4, 5-b] indoles and methods of use
|
|
CA2742320A1
(en)
|
2008-10-31 |
2010-05-06 |
Medivation Technologies, Inc. |
Pyrido[4,3-b]indoles containing rigid moieties
|
|
EP2385829B1
(en)
|
2009-01-09 |
2018-08-01 |
Board of Regents of the University of Texas System |
Pro-neurogenic compounds
|
|
US8362277B2
(en)
|
2009-01-09 |
2013-01-29 |
Board Of Regents Of The University Of Texas System |
Pro-neurogenic compounds
|
|
US9962368B2
(en)
|
2009-01-09 |
2018-05-08 |
Board Of Regents Of The University Of Texas System |
Pro-neurogenic compounds
|
|
TW201038569A
(en)
|
2009-02-16 |
2010-11-01 |
Abbott Gmbh & Co Kg |
Heterocyclic compounds, pharmaceutical compositions containing them, and their use in therapy
|
|
AU2010282990B2
(en)
|
2009-04-29 |
2015-11-05 |
Medivation Technologies, Inc. |
Pyrido [4, 3-b] indoles and methods of use
|
|
EP2424364A4
(en)
|
2009-04-29 |
2012-12-19 |
Medivation Technologies Inc |
PYRIDO [4.3-B] INDOLES AND METHODS OF USE
|
|
WO2011014695A1
(en)
|
2009-07-29 |
2011-02-03 |
Medivation Technologies, Inc. |
New 2,3,4,5-tetrahydro-1h-pyrido[4,3-b] indoles and methods of use
|
|
US20130137705A1
(en)
|
2009-09-23 |
2013-05-30 |
Sarvajit Chakravarty |
Pyrido[3,4-b]indoles and methods of use
|
|
AU2010298168B2
(en)
|
2009-09-23 |
2015-11-19 |
Medivation Technologies, Inc. |
Pyrido(3,4-b)indoles and methods of use
|
|
AU2010298169B2
(en)
|
2009-09-23 |
2015-10-29 |
Medivation Technologies, Inc. |
Bridged heterocyclic compounds and methods of use
|
|
JP5779183B2
(ja)
|
2009-09-23 |
2015-09-16 |
メディベイション テクノロジーズ， インコーポレイテッド |
ピリド［４，３−ｂ］インドールおよび使用方法
|
|
US20130172320A1
(en)
|
2010-02-18 |
2013-07-04 |
Sarvajit Chakravarty |
Pyrido [4,3-b] indole and pyrido [3,4-b] indole derivatives and methods of use
|
|
WO2011103433A1
(en)
|
2010-02-18 |
2011-08-25 |
Medivation Technologies, Inc. |
Pyrido[4,3-b]indole and pyrido[3,4-b]indole derivatives and methods of use
|
|
WO2011103485A1
(en)
|
2010-02-18 |
2011-08-25 |
Medivation Technologies, Inc. |
Fused tetracyclic pyrido[4,3-b]indole and pyrido[3,4-b]indole derivatives and methods of use
|
|
US9193728B2
(en)
|
2010-02-18 |
2015-11-24 |
Medivation Technologies, Inc. |
Fused tetracyclic pyrido [4,3-B] indole and pyrido [3,4-B] indole derivatives and methods of use
|
|
WO2011103448A1
(en)
|
2010-02-19 |
2011-08-25 |
Medivation Technologies, Inc. |
Methods and compositions for treating psychotic disorders using antipsychotic combination therapy
|
|
US9187471B2
(en)
|
2010-02-19 |
2015-11-17 |
Medivation Technologies, Inc. |
Pyrido [4,3-b] indole and pyrido [3,4-b] indole derivatives and methods of use
|
|
CN103415289B
(zh)
|
2010-07-07 |
2017-04-12 |
得克萨斯州大学系统董事会 |
前神经原性化合物
|
|
US20140303144A1
(en)
|
2011-02-18 |
2014-10-09 |
Medivation Technologies, Inc. |
Compounds and methods of treating hypertension
|
|
US9035056B2
(en)
|
2011-02-18 |
2015-05-19 |
Medivation Technologies, Inc. |
Pyrido[4,3-b]indole and pyrido[3,4-b]indole derivatives and methods of use
|
|
WO2012112962A1
(en)
|
2011-02-18 |
2012-08-23 |
Medivation Technologies, Inc. |
Compounds and methods of treating diabetes
|
|
IN2013MN01699A
(enExample)
|
2011-02-18 |
2015-06-12 |
Medivation Technologies Inc |
|
|
EP2887805A4
(en)
|
2012-08-22 |
2016-08-17 |
Medivation Technologies Inc |
COMPOUNDS AND METHOD FOR TREATING BLOOD HIGH PRESSURE
|
|
WO2014031170A1
(en)
|
2012-08-22 |
2014-02-27 |
Medivation Technologies, Inc. |
Pyrido[4,3-b]indole and pyrido[3,4-b]indole derivatives and methods of use
|
|
EP2925129A4
(en)
|
2012-08-24 |
2016-06-08 |
Univ Texas |
PRO-NEUROGENIC COMPOUNDS
|