ATE191486T1 - Pseudo-oder nicht peptidartige bradykinin rezeptor antagoniste - Google Patents
Pseudo-oder nicht peptidartige bradykinin rezeptor antagonisteInfo
- Publication number
- ATE191486T1 ATE191486T1 AT94929158T AT94929158T ATE191486T1 AT E191486 T1 ATE191486 T1 AT E191486T1 AT 94929158 T AT94929158 T AT 94929158T AT 94929158 T AT94929158 T AT 94929158T AT E191486 T1 ATE191486 T1 AT E191486T1
- Authority
- AT
- Austria
- Prior art keywords
- bradykinin
- pseudo
- receptor antagonist
- bradykinin receptor
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/18—Kallidins; Bradykinins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11855893A | 1993-09-09 | 1993-09-09 | |
US11934193A | 1993-09-09 | 1993-09-09 | |
US08/118,981 US5444048A (en) | 1992-10-08 | 1993-09-09 | Bradykinin antagonist pseudopeptide derivatives of olefinic aminoalkanoic acids |
US08/118,550 US5552383A (en) | 1992-10-08 | 1993-09-09 | Bradykinin antagonist pseudopeptide derivatives of aminoalkanoic acids and related olefins |
US28190894A | 1994-07-28 | 1994-07-28 | |
US28190694A | 1994-07-28 | 1994-07-28 | |
US08/281,904 US5686565A (en) | 1992-10-08 | 1994-07-28 | Bradykinin antagonist pseudopeptide derivatives of aminoalkanoic acids and related olefins |
US08/281,907 US5541286A (en) | 1992-10-08 | 1994-07-28 | Bradykinin antagonist pseudopeptide derivatives of olefinic aminoalkanoic acids |
PCT/US1994/010128 WO1995007294A1 (en) | 1993-09-09 | 1994-09-09 | Pseudo- and non-peptide bradykinin receptor antagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE191486T1 true ATE191486T1 (de) | 2000-04-15 |
Family
ID=27574846
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT94929158T ATE191486T1 (de) | 1993-09-09 | 1994-09-09 | Pseudo-oder nicht peptidartige bradykinin rezeptor antagoniste |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0716661B1 (de) |
JP (1) | JPH11500100A (de) |
AT (1) | ATE191486T1 (de) |
CA (1) | CA2171446C (de) |
DE (1) | DE69423899T2 (de) |
ES (1) | ES2148347T3 (de) |
WO (1) | WO1995007294A1 (de) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0813544B1 (de) * | 1994-03-09 | 2004-10-27 | Cortech, Inc. | Bradykinin-antagonist peptide mit n-substituierten glycinen |
FR2746647B1 (fr) * | 1996-03-27 | 1998-05-15 | Oreal | Composition apaisante comprenant un extrait d'iridacee |
DE69601765T2 (de) * | 1995-09-07 | 1999-07-08 | Oreal | Extrakt von Iridaceen und Zusammensetzungen, die ihn enthalten |
FR2739553B1 (fr) * | 1995-10-06 | 1998-01-02 | Oreal | Utilisation d'antagonistes de la bradykinine pour stimuler ou induire la pousse des cheveux et/ou stopper leur chute |
DE19612067A1 (de) * | 1996-03-27 | 1997-10-02 | Hoechst Ag | Verwendung von Bradykinin-Antagonisten zur Herstellung von Arzneimitteln zur Behandlung von chronisch fibrogenetischen Lebererkrankungen und akuten Lebererkrankungen |
DE19642289A1 (de) * | 1996-10-14 | 1998-04-16 | Hoechst Ag | Verwendung von Bradykinin-Antagonisten zur Herstellung von Arzneimitteln zur Behandlung und Prävention der Alzheimer'schen Krankheit |
FR2756566B1 (fr) * | 1996-12-04 | 1999-01-08 | Fournier Ind & Sante | Peptides agonistes du recepteur b2 de la bradykinine, procede de preparation et utilisation en therapeutique |
AU8811401A (en) * | 2000-09-25 | 2002-04-02 | Toray Industries | Spiro compounds and adhesion molecule inhibitors containing the same as the active ingredient |
AU2003268512A1 (en) | 2002-09-09 | 2004-03-29 | Janssen Pharmaceutica N.V. | Hydroxy alkyl substituted 1,3,8-triazaspiro[4.5]decan-4-one derivatives useful for the treatment of ORL-1 receptor mediated disorders |
PL1725553T3 (pl) | 2004-03-11 | 2008-10-31 | Idorsia Pharmaceuticals Ltd | Pochodne tetrahydropirydoindolu |
EP1740171B1 (de) | 2004-03-11 | 2010-06-09 | Actelion Pharmaceuticals Ltd. | Indol-1-yl-essigsäurederivate |
AU2005276640A1 (en) | 2004-08-26 | 2006-03-02 | Actelion Pharmaceuticals Ltd. | 2-sulfanyl-benzoimidazol-1-yl-acetic acid derivatives as CRTH2 antagonists |
EP2061765B1 (de) * | 2006-09-01 | 2014-10-22 | Senhwa Biosciences, Inc. | Serin-Threonin-Proteinkinase- und PARP-Modulatoren |
CA2670858C (en) | 2006-11-28 | 2015-01-13 | Janssen Pharmaceutica N.V. | Salts of 3-(3-amino-2-(r)-hydroxy-propyl)-1-(4-fluoro-phenyl)-8-(8-methyl-naphthalen-1-ylmethyl)-1,3,8-triaza-spiro[4.5]decan-4-one |
EP2150552B1 (de) | 2007-04-09 | 2013-01-02 | Janssen Pharmaceutica NV | 1,3,8-trisubstituierte-1,3,8-triaza-spiro[4.5]decan-4-on derivate als liganden des orl-1 rezeptors zur behandlung von angst und depression |
CN104387382A (zh) | 2008-03-24 | 2015-03-04 | 梅迪维新技术公司 | 吡啶并[3,4-b]吲哚和应用方法 |
EP2480079A4 (de) * | 2009-09-23 | 2015-04-08 | Medivation Technologies Inc | Pyrido-(3,4-b-)indole und verwendungsverfahren dafür |
KR20230038457A (ko) | 2020-06-10 | 2023-03-20 | 알리고스 테라퓨틱스 인코포레이티드 | 코로나바이러스, 피코르나바이러스 및 노로바이러스 감염을 치료하기 위한 항바이러스 화합물 |
PE20240775A1 (es) | 2021-07-09 | 2024-04-17 | Aligos Therapeutics Inc | Compuestos antivirales |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1989009230A1 (en) * | 1988-03-25 | 1989-10-05 | Administrators Of The Tulane Educational Fund | Therapeutic peptides |
AU1873992A (en) * | 1991-04-19 | 1992-11-17 | Nova Technology Limited Partnership | Bradykinin antagonist peptides |
US5521158A (en) * | 1992-10-08 | 1996-05-28 | Scios Nova Inc. | Pseudopeptide bradykinin receptor antagonists |
-
1994
- 1994-09-09 CA CA002171446A patent/CA2171446C/en not_active Expired - Lifetime
- 1994-09-09 JP JP7508795A patent/JPH11500100A/ja active Pending
- 1994-09-09 ES ES94929158T patent/ES2148347T3/es not_active Expired - Lifetime
- 1994-09-09 AT AT94929158T patent/ATE191486T1/de active
- 1994-09-09 DE DE69423899T patent/DE69423899T2/de not_active Expired - Lifetime
- 1994-09-09 EP EP94929158A patent/EP0716661B1/de not_active Expired - Lifetime
- 1994-09-09 WO PCT/US1994/010128 patent/WO1995007294A1/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
EP0716661A1 (de) | 1996-06-19 |
DE69423899D1 (de) | 2000-05-11 |
DE69423899T2 (de) | 2000-11-09 |
EP0716661B1 (de) | 2000-04-05 |
JPH11500100A (ja) | 1999-01-06 |
CA2171446A1 (en) | 1995-03-16 |
CA2171446C (en) | 2004-11-23 |
WO1995007294A1 (en) | 1995-03-16 |
ES2148347T3 (es) | 2000-10-16 |
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