DE69032258T2 - Antikoagulierende Peptide - Google Patents

Antikoagulierende Peptide

Info

Publication number
DE69032258T2
DE69032258T2 DE69032258T DE69032258T DE69032258T2 DE 69032258 T2 DE69032258 T2 DE 69032258T2 DE 69032258 T DE69032258 T DE 69032258T DE 69032258 T DE69032258 T DE 69032258T DE 69032258 T2 DE69032258 T2 DE 69032258T2
Authority
DE
Germany
Prior art keywords
anticoagulant peptides
anticoagulant
peptides
relates
peptide derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69032258T
Other languages
English (en)
Other versions
DE69032258D1 (de
Inventor
John L Krstenansky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Merrell Dow Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc
Publication of DE69032258D1 publication Critical patent/DE69032258D1/de
Application granted granted Critical
Publication of DE69032258T2 publication Critical patent/DE69032258T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69032258T 1989-10-03 1990-10-03 Antikoagulierende Peptide Expired - Fee Related DE69032258T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41633689A 1989-10-03 1989-10-03

Publications (2)

Publication Number Publication Date
DE69032258D1 DE69032258D1 (de) 1998-05-28
DE69032258T2 true DE69032258T2 (de) 1999-03-11

Family

ID=23649539

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69032258T Expired - Fee Related DE69032258T2 (de) 1989-10-03 1990-10-03 Antikoagulierende Peptide

Country Status (17)

Country Link
EP (1) EP0421367B1 (de)
JP (1) JP2899391B2 (de)
KR (1) KR0154528B1 (de)
CN (1) CN1050720A (de)
AT (1) ATE165369T1 (de)
AU (1) AU634280B2 (de)
CA (1) CA2026376C (de)
DE (1) DE69032258T2 (de)
ES (1) ES2117624T3 (de)
FI (1) FI904852A0 (de)
HU (1) HU207103B (de)
IE (1) IE903532A1 (de)
IL (1) IL95863A0 (de)
NO (1) NO904292L (de)
NZ (1) NZ235497A (de)
PT (1) PT95486A (de)
ZA (1) ZA907742B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU633128B2 (en) * 1987-01-23 1993-01-21 Merrell Dow Pharmaceuticals Inc. Anticoagulant peptides
KR100195424B1 (ko) * 1990-07-24 1999-06-15 슈테펜엘.네스비트 항응고성 펩티드
US5574012A (en) * 1990-07-24 1996-11-12 Merrell Pharmaceuticals Inc. Analogs of hirudin having anti-platelet activity
ZA915658B (en) * 1990-07-24 1992-05-27 Merrell Dow Pharma Analogs of hirudin having antiplatelet activity
EP0531537B1 (de) * 1991-03-05 1996-09-11 Japan Energy Corporation Hirudinanalog oder dessen salz, dessen herstellung und das als aktiven bestandteil enthaltende antikoagulanz
IT1250689B (it) * 1991-07-22 1995-04-21 Marco Gerna Analoghi dell'irudina e procedimento per la loro preparazione
WO1993004082A1 (en) * 1991-08-20 1993-03-04 Baxter International Inc. Analogs of hirudin
DK0702696T3 (da) * 1993-06-11 2003-11-17 Merrell Pharma Inc Trifunktionelle antithrombin- og antiblodpladepeptider
TWI315494B (en) 2006-06-06 2009-10-01 Silicon Motion Inc Memory module with display functions and display unit thereof
CN104193809B (zh) * 2014-09-28 2016-08-17 顾玉奎 一种凝血酶抑制及其制备方法、应用
CN110981953B (zh) * 2019-12-13 2021-10-08 首都医科大学 一种多肽和多肽的应用及包含多肽的组合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU633128B2 (en) * 1987-01-23 1993-01-21 Merrell Dow Pharmaceuticals Inc. Anticoagulant peptides
CA1341032C (en) * 1987-01-23 2000-06-20 John L. Krstenansky Anticoagulant peptides
AU3098289A (en) * 1988-03-04 1989-09-07 Biogen, Inc. Hirudin peptides
ZA899247B (en) * 1988-12-07 1990-09-26 Merrell Dow Pharma Anticoagulant peptides
FR2667071A1 (fr) * 1990-09-26 1992-03-27 Adir Nouveaux derives de peptides et de pseudopeptides therapeutiquement actifs dans la cascade de coagulation sanguine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.

Also Published As

Publication number Publication date
JPH03120297A (ja) 1991-05-22
IL95863A0 (en) 1991-07-18
CA2026376A1 (en) 1991-04-04
ES2117624T3 (es) 1998-08-16
AU634280B2 (en) 1993-02-18
HU207103B (en) 1993-03-01
NO904292L (no) 1991-04-04
IE903532A1 (en) 1991-04-10
EP0421367B1 (de) 1998-04-22
KR0154528B1 (ko) 1998-10-15
CN1050720A (zh) 1991-04-17
NO904292D0 (no) 1990-10-02
JP2899391B2 (ja) 1999-06-02
DE69032258D1 (de) 1998-05-28
HUT55800A (en) 1991-06-28
KR910007960A (ko) 1991-05-30
EP0421367A1 (de) 1991-04-10
FI904852A0 (fi) 1990-10-02
AU6368890A (en) 1991-04-11
ATE165369T1 (de) 1998-05-15
NZ235497A (en) 1993-05-26
ZA907742B (en) 1991-07-31
CA2026376C (en) 2002-01-01
HU906270D0 (en) 1991-03-28
PT95486A (pt) 1991-07-05

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Legal Events

Date Code Title Description
8332 No legal effect for de
8370 Indication related to discontinuation of the patent is to be deleted
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee