ES2117624T3 - Peptidos anticoagulantes. - Google Patents

Peptidos anticoagulantes.

Info

Publication number
ES2117624T3
ES2117624T3 ES90118903T ES90118903T ES2117624T3 ES 2117624 T3 ES2117624 T3 ES 2117624T3 ES 90118903 T ES90118903 T ES 90118903T ES 90118903 T ES90118903 T ES 90118903T ES 2117624 T3 ES2117624 T3 ES 2117624T3
Authority
ES
Spain
Prior art keywords
anticoagulant peptides
anticoagulant
peptides
relative
peptide derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90118903T
Other languages
English (en)
Inventor
John L Krstenansky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Merrell Dow Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc
Application granted granted Critical
Publication of ES2117624T3 publication Critical patent/ES2117624T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

ESTA INVENCION ES RELATIVA A DERIVADOS PEPTIDOS LOS CUALES SE USAN COMO AGENTES ANTICOAGULANTES
ES90118903T 1989-10-03 1990-10-03 Peptidos anticoagulantes. Expired - Lifetime ES2117624T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41633689A 1989-10-03 1989-10-03

Publications (1)

Publication Number Publication Date
ES2117624T3 true ES2117624T3 (es) 1998-08-16

Family

ID=23649539

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90118903T Expired - Lifetime ES2117624T3 (es) 1989-10-03 1990-10-03 Peptidos anticoagulantes.

Country Status (17)

Country Link
EP (1) EP0421367B1 (es)
JP (1) JP2899391B2 (es)
KR (1) KR0154528B1 (es)
CN (1) CN1050720A (es)
AT (1) ATE165369T1 (es)
AU (1) AU634280B2 (es)
CA (1) CA2026376C (es)
DE (1) DE69032258T2 (es)
ES (1) ES2117624T3 (es)
FI (1) FI904852A7 (es)
HU (1) HU207103B (es)
IE (1) IE903532A1 (es)
IL (1) IL95863A0 (es)
NO (1) NO904292L (es)
NZ (1) NZ235497A (es)
PT (1) PT95486A (es)
ZA (1) ZA907742B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU633128B2 (en) * 1987-01-23 1993-01-21 Merrell Dow Pharmaceuticals Inc. Anticoagulant peptides
US5574012A (en) * 1990-07-24 1996-11-12 Merrell Pharmaceuticals Inc. Analogs of hirudin having anti-platelet activity
CA2086243C (en) * 1990-07-24 2001-10-02 John L. Krstenansky Anticoagulant peptides
ZA915658B (en) * 1990-07-24 1992-05-27 Merrell Dow Pharma Analogs of hirudin having antiplatelet activity
AU660171B2 (en) * 1991-03-05 1995-06-15 Fuji Yakuhin Kogyo Kabushiki Kaisha Hirudin analogue or salt thereof, production thereof, and anticoagulant containing the same as active ingredient
IT1250689B (it) * 1991-07-22 1995-04-21 Marco Gerna Analoghi dell'irudina e procedimento per la loro preparazione
WO1993004082A1 (en) * 1991-08-20 1993-03-04 Baxter International Inc. Analogs of hirudin
ES2199963T3 (es) * 1993-06-11 2004-03-01 Merrell Pharmaceuticals Inc. Peptidos trifuncionales antitrombina y antiplaquetarios.
TWI315494B (en) 2006-06-06 2009-10-01 Silicon Motion Inc Memory module with display functions and display unit thereof
CN104193809B (zh) * 2014-09-28 2016-08-17 顾玉奎 一种凝血酶抑制及其制备方法、应用
CN110981953B (zh) * 2019-12-13 2021-10-08 首都医科大学 一种多肽和多肽的应用及包含多肽的组合物
KR20230158005A (ko) 2021-03-18 2023-11-17 씨젠 인크. 생물학적 활성 화합물의 내재화된 접합체로부터의 선택적 약물 방출

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU633128B2 (en) * 1987-01-23 1993-01-21 Merrell Dow Pharmaceuticals Inc. Anticoagulant peptides
CA1341032C (en) * 1987-01-23 2000-06-20 John L. Krstenansky Anticoagulant peptides
EP0333356A3 (en) * 1988-03-04 1990-12-19 Biogen, Inc. Hirudin peptides
AU630132B2 (en) * 1988-12-07 1992-10-22 Merrell Dow Pharmaceuticals Inc. Anticoagulant peptides
FR2667071A1 (fr) * 1990-09-26 1992-03-27 Adir Nouveaux derives de peptides et de pseudopeptides therapeutiquement actifs dans la cascade de coagulation sanguine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.

Also Published As

Publication number Publication date
HUT55800A (en) 1991-06-28
KR910007960A (ko) 1991-05-30
ATE165369T1 (de) 1998-05-15
IE903532A1 (en) 1991-04-10
EP0421367A1 (en) 1991-04-10
NZ235497A (en) 1993-05-26
JPH03120297A (ja) 1991-05-22
DE69032258D1 (de) 1998-05-28
CA2026376C (en) 2002-01-01
AU634280B2 (en) 1993-02-18
JP2899391B2 (ja) 1999-06-02
FI904852A0 (fi) 1990-10-02
FI904852A7 (fi) 1991-04-04
DE69032258T2 (de) 1999-03-11
HU207103B (en) 1993-03-01
HU906270D0 (en) 1991-03-28
NO904292D0 (no) 1990-10-02
PT95486A (pt) 1991-07-05
ZA907742B (en) 1991-07-31
NO904292L (no) 1991-04-04
EP0421367B1 (en) 1998-04-22
AU6368890A (en) 1991-04-11
CN1050720A (zh) 1991-04-17
IL95863A0 (en) 1991-07-18
CA2026376A1 (en) 1991-04-04
KR0154528B1 (ko) 1998-10-15

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