JP2018507899A5 - - Google Patents

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JP2018507899A5
JP2018507899A5 JP2017548107A JP2017548107A JP2018507899A5 JP 2018507899 A5 JP2018507899 A5 JP 2018507899A5 JP 2017548107 A JP2017548107 A JP 2017548107A JP 2017548107 A JP2017548107 A JP 2017548107A JP 2018507899 A5 JP2018507899 A5 JP 2018507899A5
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JP
Japan
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dimethoxy
dihydroquinazolin
phenyl
dimethylphenyl
oxo
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JP2017548107A
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Japanese (ja)
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JP2018507899A (ja
JP6903585B2 (ja
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Priority claimed from PCT/IB2016/000443 external-priority patent/WO2016147053A1/en
Publication of JP2018507899A publication Critical patent/JP2018507899A/ja
Publication of JP2018507899A5 publication Critical patent/JP2018507899A5/ja
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JP2017548107A 2015-03-13 2016-03-10 補体関連疾患の治療のための組成物および治療方法 Active JP6903585B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562132572P 2015-03-13 2015-03-13
US62/132,572 2015-03-13
US201562264768P 2015-12-08 2015-12-08
US62/264,768 2015-12-08
PCT/IB2016/000443 WO2016147053A1 (en) 2015-03-13 2016-03-10 Compositions and therapeutic methods for the treatment of complement-associated diseases

Publications (3)

Publication Number Publication Date
JP2018507899A JP2018507899A (ja) 2018-03-22
JP2018507899A5 true JP2018507899A5 (enExample) 2019-04-18
JP6903585B2 JP6903585B2 (ja) 2021-07-14

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JP2017548107A Active JP6903585B2 (ja) 2015-03-13 2016-03-10 補体関連疾患の治療のための組成物および治療方法

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US (2) US10111885B2 (enExample)
EP (1) EP3268007B1 (enExample)
JP (1) JP6903585B2 (enExample)
KR (1) KR102662814B1 (enExample)
CN (2) CN114984016A (enExample)
JO (1) JO3789B1 (enExample)
TW (1) TWI705815B (enExample)
WO (1) WO2016147053A1 (enExample)

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DK2421533T3 (en) 2009-04-22 2019-01-07 Resverlogix Corp Hitherto unknown anti-inflammatory agents
JP6903585B2 (ja) 2015-03-13 2021-07-14 レスバーロジックス コーポレイション 補体関連疾患の治療のための組成物および治療方法
JP7173965B2 (ja) 2016-10-19 2022-11-16 アレクシオン ファーマシューティカルズ, インコーポレイテッド 試料中の非結合C5aの定量化方法
JP7096240B2 (ja) * 2016-10-19 2022-07-05 アレクシオン ファーマシューティカルズ, インコーポレイテッド 試料中の非結合c5の定量化方法
JP7281470B2 (ja) * 2018-01-19 2023-05-25 イドーシア ファーマシューティカルズ リミテッド C5a受容体調節剤
CN108484510B (zh) * 2018-05-18 2020-05-05 东南大学 一种基于brd4抑制剂rvx-208的衍生物及其制备方法和应用
AU2020377539B2 (en) 2019-11-05 2025-05-29 Resverlogix Corp. Methods of treatment and/or prevention of major adverse cardiovascular events (mace) with a combination of a bet bromodomain inhibitor and a sodium dependent glucose transport 2 inhibitor
WO2021154941A1 (en) * 2020-01-31 2021-08-05 Alnylam Pharmaceuticals, Inc. Complement component c5 irna compositions for use in the treatment of amyotrophic lateral sclerosis (als)
EP4185592A4 (en) 2020-07-20 2024-08-21 Annexon, Inc. COMPLEMENT FACTOR INHIBITORS AND THEIR USES
CA3197706A1 (en) * 2020-10-30 2022-05-05 Resverlogix Corp. Methods for improving renal function with a combination of a bet bromodomain inhibitor and a sodium dependent glucose transport 2 inhibitor
CN113754594B (zh) * 2021-09-16 2025-01-21 中国药科大学 喹唑啉酮类化合物或其可药用的盐、异构体及其制备方法、药物组合物和用途
KR20240135818A (ko) 2022-01-14 2024-09-12 애넥슨, 인코포레이티드 보체 인자의 저해제 및 이의 용도
TW202543631A (zh) * 2024-03-14 2025-11-16 美商凡況生化公司 嗒嗪酮c5ar1拮抗劑及其用途

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