JP6903585B2 - 補体関連疾患の治療のための組成物および治療方法 - Google Patents

補体関連疾患の治療のための組成物および治療方法 Download PDF

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JP6903585B2
JP6903585B2 JP2017548107A JP2017548107A JP6903585B2 JP 6903585 B2 JP6903585 B2 JP 6903585B2 JP 2017548107 A JP2017548107 A JP 2017548107A JP 2017548107 A JP2017548107 A JP 2017548107A JP 6903585 B2 JP6903585 B2 JP 6903585B2
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dimethoxy
dihydroquinazoline
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JP2018507899A (ja
JP2018507899A5 (enExample
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シルヴィア・ヴァシャク
エヴェリナ・ビー・クリコフスキー
クリストファー・アール・エイ・ハリデイ
ディーン・ギラム
ローラ・エム・ツジカワ
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レスバーロジックス コーポレイション
レスバーロジックス コーポレイション
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    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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JP2017548107A 2015-03-13 2016-03-10 補体関連疾患の治療のための組成物および治療方法 Active JP6903585B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562132572P 2015-03-13 2015-03-13
US62/132,572 2015-03-13
US201562264768P 2015-12-08 2015-12-08
US62/264,768 2015-12-08
PCT/IB2016/000443 WO2016147053A1 (en) 2015-03-13 2016-03-10 Compositions and therapeutic methods for the treatment of complement-associated diseases

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JP2018507899A JP2018507899A (ja) 2018-03-22
JP2018507899A5 JP2018507899A5 (enExample) 2019-04-18
JP6903585B2 true JP6903585B2 (ja) 2021-07-14

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US (2) US10111885B2 (enExample)
EP (1) EP3268007B1 (enExample)
JP (1) JP6903585B2 (enExample)
KR (1) KR102662814B1 (enExample)
CN (2) CN107530356A (enExample)
CA (1) CA2977308A1 (enExample)
JO (1) JO3789B1 (enExample)
TW (1) TWI705815B (enExample)
WO (1) WO2016147053A1 (enExample)

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KR20220098757A (ko) * 2019-11-05 2022-07-12 리스버로직스 코퍼레이션 Bet 브로모도메인 억제제 및 나트륨 의존 글루코스 수송 2 억제제와 병용하여 주요 부정적 심혈관 사건 (mace)을 치료 및/또는 예방하는 방법
WO2021154941A1 (en) * 2020-01-31 2021-08-05 Alnylam Pharmaceuticals, Inc. Complement component c5 irna compositions for use in the treatment of amyotrophic lateral sclerosis (als)
CN116261564A (zh) 2020-07-20 2023-06-13 安尼艾克松股份有限公司 补体因子的抑制剂和其用途
CN113754594B (zh) * 2021-09-16 2025-01-21 中国药科大学 喹唑啉酮类化合物或其可药用的盐、异构体及其制备方法、药物组合物和用途
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