JP2017535261A5 - - Google Patents
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- JP2017535261A5 JP2017535261A5 JP2017523279A JP2017523279A JP2017535261A5 JP 2017535261 A5 JP2017535261 A5 JP 2017535261A5 JP 2017523279 A JP2017523279 A JP 2017523279A JP 2017523279 A JP2017523279 A JP 2017523279A JP 2017535261 A5 JP2017535261 A5 JP 2017535261A5
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020208069A JP7792114B2 (ja) | 2014-10-31 | 2020-12-16 | Ｃａｒｔ細胞における遺伝子発現の改変およびその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462073651P | 2014-10-31 | 2014-10-31 | |
| US62/073,651 | 2014-10-31 | ||
| PCT/US2015/055799 WO2016069283A1 (en) | 2014-10-31 | 2015-10-15 | Altering gene expression in cart cells and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020208069A Division JP7792114B2 (ja) | 2014-10-31 | 2020-12-16 | Ｃａｒｔ細胞における遺伝子発現の改変およびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017535261A JP2017535261A (ja) | 2017-11-30 |
| JP2017535261A5 true JP2017535261A5 (show.php) | 2018-11-15 |
| JP6879910B2 JP6879910B2 (ja) | 2021-06-02 |
Family
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Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017523279A Active JP6879910B2 (ja) | 2014-10-31 | 2015-10-15 | Ｃａｒｔ細胞における遺伝子発現の改変およびその使用 |
| JP2017523296A Ceased JP2018500006A (ja) | 2014-10-31 | 2015-10-15 | 改変ｔ細胞における遺伝子発現の改変およびその使用 |
| JP2020208069A Active JP7792114B2 (ja) | 2014-10-31 | 2020-12-16 | Ｃａｒｔ細胞における遺伝子発現の改変およびその使用 |
| JP2023004286A Active JP7657474B2 (ja) | 2014-10-31 | 2023-01-16 | Ｃａｒｔ細胞における遺伝子発現の改変およびその使用 |
| JP2025043131A Pending JP2025089344A (ja) | 2014-10-31 | 2025-03-18 | Ｃａｒｔ細胞における遺伝子発現の改変およびその使用 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017523296A Ceased JP2018500006A (ja) | 2014-10-31 | 2015-10-15 | 改変ｔ細胞における遺伝子発現の改変およびその使用 |
| JP2020208069A Active JP7792114B2 (ja) | 2014-10-31 | 2020-12-16 | Ｃａｒｔ細胞における遺伝子発現の改変およびその使用 |
| JP2023004286A Active JP7657474B2 (ja) | 2014-10-31 | 2023-01-16 | Ｃａｒｔ細胞における遺伝子発現の改変およびその使用 |
| JP2025043131A Pending JP2025089344A (ja) | 2014-10-31 | 2025-03-18 | Ｃａｒｔ細胞における遺伝子発現の改変およびその使用 |
Country Status (13)
| Country | Link |
|---|---|
| US (7) | US20170335331A1 (show.php) |
| EP (4) | EP4219725A3 (show.php) |
| JP (5) | JP6879910B2 (show.php) |
| KR (5) | KR20240075936A (show.php) |
| CN (3) | CN107206024B (show.php) |
| AU (4) | AU2015339743C1 (show.php) |
| BR (1) | BR112017008693A2 (show.php) |
| CA (2) | CA2964948A1 (show.php) |
| EA (1) | EA201790953A1 (show.php) |
| ES (1) | ES2983094T3 (show.php) |
| MX (2) | MX2017005698A (show.php) |
| PL (1) | PL3215166T3 (show.php) |
| WO (2) | WO2016069283A1 (show.php) |
Families Citing this family (207)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2853829C (en) | 2011-07-22 | 2023-09-26 | President And Fellows Of Harvard College | Evaluation and improvement of nuclease cleavage specificity |
| KR102073901B1 (ko) | 2011-09-08 | 2020-02-05 | 예다 리서치 앤드 디벨럽먼트 캄파니 리미티드 | 항 제3자 중심 기억 ｔ 세포, 이의 제조 방법, 및 이식 및 질환 치료에서의 이의 용도 |
| US9163284B2 (en) | 2013-08-09 | 2015-10-20 | President And Fellows Of Harvard College | Methods for identifying a target site of a Cas9 nuclease |
| US9359599B2 (en) | 2013-08-22 | 2016-06-07 | President And Fellows Of Harvard College | Engineered transcription activator-like effector (TALE) domains and uses thereof |
| US9340800B2 (en) | 2013-09-06 | 2016-05-17 | President And Fellows Of Harvard College | Extended DNA-sensing GRNAS |
| US9526784B2 (en) | 2013-09-06 | 2016-12-27 | President And Fellows Of Harvard College | Delivery system for functional nucleases |
| US9322037B2 (en) | 2013-09-06 | 2016-04-26 | President And Fellows Of Harvard College | Cas9-FokI fusion proteins and uses thereof |
| US9840699B2 (en) | 2013-12-12 | 2017-12-12 | President And Fellows Of Harvard College | Methods for nucleic acid editing |
| JP6206893B2 (ja) | 2014-03-05 | 2017-10-04 | 国立大学法人神戸大学 | 標的化したｄｎａ配列の核酸塩基を特異的に変換するゲノム配列の改変方法及びそれに用いる分子複合体 |
| US11390921B2 (en) | 2014-04-01 | 2022-07-19 | Adaptive Biotechnologies Corporation | Determining WT-1 specific T cells and WT-1 specific T cell receptors (TCRs) |
| SG11201608862SA (en) | 2014-04-23 | 2016-11-29 | Juno Therapeutics Inc | Methods for isolating, culturing, and genetically engineering immune cell populations for adoptive therapy |
| WO2016022363A2 (en) | 2014-07-30 | 2016-02-11 | President And Fellows Of Harvard College | Cas9 proteins including ligand-dependent inteins |
| BR112017008693A2 (pt) | 2014-10-31 | 2018-02-27 | The Trustees Of The University Of Pennsylvania | célula t modificada, métodos para gerar uma célula t modificada, para tratar uma doença ou condição, para estimular uma resposta imune mediada por célula t e para terapia de transferência de célula adotiva, uso de uma célula t modificada, e, composição. |
| CA2969619A1 (en) | 2014-12-03 | 2016-06-09 | Agilent Technologies, Inc. | Guide rna with chemical modifications |
| SG10201913124RA (en) | 2015-02-06 | 2020-03-30 | Nat Univ Singapore | Methods for enhancing efficacy of therapeutic immune cells |
| MX2017012407A (es) * | 2015-03-27 | 2018-03-07 | Harvard College | Celulas t modificadas y métodos para hacer y usar las mismas. |
| AU2016246450B2 (en) | 2015-04-06 | 2022-03-17 | Agilent Technologies, Inc. | Chemically modified guide RNAs for CRISPR/Cas-mediated gene regulation |
| CN107921148A (zh) | 2015-05-08 | 2018-04-17 | 哈佛学院校长同事会 | 通用供体干细胞和相关方法 |
| DK3322425T3 (da) | 2015-07-16 | 2023-06-12 | Yeda Res & Dev | Genmodificerede anti-tredjeparts-centralhukommelse-t-celler og brug af samme i immunterapi |
| CA2993431A1 (en) | 2015-07-31 | 2017-02-09 | Regents Of The University Of Minnesota | Nuclease based knockouts of immunological checkpoint genes in immune cells |
| ES2883116T3 (es) | 2015-10-05 | 2021-12-07 | Prec Biosciences Inc | Meganucleasas diseñadas con secuencias de reconocimiento encontradas en el gen de la región constante alfa del receptor de células T humanas |
| CN108601821B (zh) | 2015-10-05 | 2023-09-19 | 精密生物科学公司 | 包含经修饰的人T细胞受体α恒定区基因的经遗传修饰的细胞 |
| IL294014B2 (en) | 2015-10-23 | 2024-07-01 | Harvard College | Nucleobase editors and uses thereof |
| WO2017090761A1 (ja) | 2015-11-27 | 2017-06-01 | 国立大学法人神戸大学 | 標的化したｄｎａ配列の核酸塩基を特異的に変換する、単子葉植物のゲノム配列の変換方法、及びそれに用いる分子複合体 |
| EP4212547A1 (en) | 2015-12-03 | 2023-07-19 | Juno Therapeutics, Inc. | Modified chimeric receptors and related compositions and methods |
| NZ782858A (en) * | 2015-12-04 | 2025-08-29 | Novartis Ag | Compositions and methods for immunooncology |
| TWI765875B (zh) | 2015-12-16 | 2022-06-01 | 美商磨石生物公司 | 新抗原辨識、製造及用途 |
| WO2017192536A1 (en) | 2016-05-02 | 2017-11-09 | University Of Kansas | Eliminating mhc restriction from the t cell receptor as a strategy for immunotherapy |
| US10767175B2 (en) | 2016-06-08 | 2020-09-08 | Agilent Technologies, Inc. | High specificity genome editing using chemically modified guide RNAs |
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| BR112017008693A2 (pt) | 2014-10-31 | 2018-02-27 | The Trustees Of The University Of Pennsylvania | célula t modificada, métodos para gerar uma célula t modificada, para tratar uma doença ou condição, para estimular uma resposta imune mediada por célula t e para terapia de transferência de célula adotiva, uso de uma célula t modificada, e, composição. |
| MY196588A (en) | 2015-03-05 | 2023-04-19 | Hutchinson Fred Cancer Res | Immunomodulatory Fusion Proteins and uses Thereof |
| MX2017012407A (es) * | 2015-03-27 | 2018-03-07 | Harvard College | Celulas t modificadas y métodos para hacer y usar las mismas. |
| US10934336B2 (en) * | 2017-04-13 | 2021-03-02 | The Trustees Of The University Of Pennsylvania | Use of gene editing to generate universal TCR re-directed T cells for adoptive immunotherapy |
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2015
- 2015-10-15 BR BR112017008693-0A patent/BR112017008693A2/pt not_active Application Discontinuation
- 2015-10-15 US US15/516,240 patent/US20170335331A1/en not_active Abandoned
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- 2015-10-15 CN CN202111354276.6A patent/CN114836385B/zh active Active
- 2015-10-15 KR KR1020177014805A patent/KR102546296B1/ko active Active
- 2015-10-15 EA EA201790953A patent/EA201790953A1/ru unknown
- 2015-10-15 EP EP23156585.4A patent/EP4219725A3/en active Pending
- 2015-10-15 KR KR1020237020503A patent/KR102781429B1/ko active Active
- 2015-10-15 US US15/516,052 patent/US11208661B2/en active Active
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- 2015-10-15 AU AU2015339743A patent/AU2015339743C1/en active Active
- 2015-10-15 WO PCT/US2015/055799 patent/WO2016069283A1/en not_active Ceased
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- 2015-10-15 JP JP2017523296A patent/JP2018500006A/ja not_active Ceased
- 2015-10-15 WO PCT/US2015/055780 patent/WO2016069282A1/en not_active Ceased
- 2015-10-15 EP EP24171941.8A patent/EP4427809A3/en active Pending
- 2015-10-15 KR KR1020177014804A patent/KR20170075013A/ko not_active Ceased
- 2015-10-15 EP EP15855146.5A patent/EP3215168B1/en active Active
- 2015-10-15 CA CA2964948A patent/CA2964948A1/en active Pending
- 2015-10-15 CA CA2964953A patent/CA2964953A1/en active Pending
- 2015-10-15 KR KR1020247040454A patent/KR20250005477A/ko active Pending
- 2015-10-15 CN CN201580071678.1A patent/CN107249606A/zh active Pending
- 2015-10-15 AU AU2015339744A patent/AU2015339744B2/en active Active
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- 2017-04-28 MX MX2023004169A patent/MX2023004169A/es unknown
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- 2018-04-25 US US15/962,379 patent/US11203758B2/en active Active
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- 2021-11-24 US US17/456,436 patent/US20220145306A1/en active Pending
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- 2023-09-15 US US18/468,043 patent/US20240279665A1/en active Pending
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