JP2016063823A5 - - Google Patents
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- JP2016063823A5 JP2016063823A5 JP2015231313A JP2015231313A JP2016063823A5 JP 2016063823 A5 JP2016063823 A5 JP 2016063823A5 JP 2015231313 A JP2015231313 A JP 2015231313A JP 2015231313 A JP2015231313 A JP 2015231313A JP 2016063823 A5 JP2016063823 A5 JP 2016063823A5
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- Prior art keywords
- reductase
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- 108090000854 Oxidoreductases Proteins 0.000 claims 72
- 102000004316 Oxidoreductases Human genes 0.000 claims 72
- QUCHWTCTBHQQDU-SCSAIBSYSA-N (R)-2-amino-4-oxopentanoic acid zwitterion Chemical compound CC(=O)C[C@@H](N)C(O)=O QUCHWTCTBHQQDU-SCSAIBSYSA-N 0.000 claims 55
- -1 ldh Proteins 0.000 claims 34
- HSJKGGMUJITCBW-UHFFFAOYSA-N 3-hydroxybutanal Chemical compound CC(O)CC=O HSJKGGMUJITCBW-UHFFFAOYSA-N 0.000 claims 28
- 108090000623 proteins and genes Proteins 0.000 claims 25
- 230000015572 biosynthetic process Effects 0.000 claims 22
- 150000001299 aldehydes Chemical class 0.000 claims 20
- PKQIDSVLSKFZQC-UHFFFAOYSA-N 3-oxobutanal Chemical compound CC(=O)CC=O PKQIDSVLSKFZQC-UHFFFAOYSA-N 0.000 claims 16
- 108060008225 Thiolase Proteins 0.000 claims 16
- 102000002932 Thiolase Human genes 0.000 claims 16
- 108090000340 Transaminases Proteins 0.000 claims 16
- 102000014898 transaminase activity proteins Human genes 0.000 claims 16
- 108091000039 acetoacetyl-CoA reductase Proteins 0.000 claims 15
- AXPZIVKEZRHGAS-UHFFFAOYSA-N 3-benzyl-5-[(2-nitrophenoxy)methyl]oxolan-2-one Chemical compound [O-][N+](=O)C1=CC=CC=C1OCC1OC(=O)C(CC=2C=CC=CC=2)C1 AXPZIVKEZRHGAS-UHFFFAOYSA-N 0.000 claims 14
- 230000009615 deamination Effects 0.000 claims 14
- 238000006481 deamination reaction Methods 0.000 claims 14
- 150000002576 ketones Chemical class 0.000 claims 14
- LVSQXDHWDCMMRJ-UHFFFAOYSA-N 4-hydroxybutan-2-one Chemical compound CC(=O)CCO LVSQXDHWDCMMRJ-UHFFFAOYSA-N 0.000 claims 13
- 244000005700 microbiome Species 0.000 claims 13
- 229920001791 ((R)-3-Hydroxybutanoyl)(n-2) Polymers 0.000 claims 12
- QHHKKMYHDBRONY-RMNRSTNRSA-N 3-hydroxybutanoyl-CoA Chemical compound O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)CC(O)C)O[C@H]1N1C2=NC=NC(N)=C2N=C1 QHHKKMYHDBRONY-RMNRSTNRSA-N 0.000 claims 12
- UNRQTHVKJQUDDF-UHFFFAOYSA-N acetylpyruvic acid Chemical compound CC(=O)CC(=O)C(O)=O UNRQTHVKJQUDDF-UHFFFAOYSA-N 0.000 claims 11
- 101150110984 phaB gene Proteins 0.000 claims 11
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 10
- 101100297400 Rhizobium meliloti (strain 1021) phaAB gene Proteins 0.000 claims 10
- 230000037361 pathway Effects 0.000 claims 10
- SUVYXKDAVYFUMG-UHFFFAOYSA-N 4-aminobutan-2-one Chemical compound CC(=O)CCN SUVYXKDAVYFUMG-UHFFFAOYSA-N 0.000 claims 9
- 102000004118 Ammonia-Lyases Human genes 0.000 claims 8
- 108090000673 Ammonia-Lyases Proteins 0.000 claims 8
- 101100398755 Escherichia coli (strain K12) ldcC gene Proteins 0.000 claims 8
- FUSUHKVFWTUUBE-UHFFFAOYSA-N buten-2-one Chemical compound CC(=O)C=C FUSUHKVFWTUUBE-UHFFFAOYSA-N 0.000 claims 8
- 102000004190 Enzymes Human genes 0.000 claims 7
- 108090000790 Enzymes Proteins 0.000 claims 7
- 101100280476 Streptococcus pneumoniae (strain ATCC BAA-255 / R6) fabM gene Proteins 0.000 claims 7
- 238000000034 method Methods 0.000 claims 7
- 108020004707 nucleic acids Proteins 0.000 claims 7
- 150000007523 nucleic acids Chemical class 0.000 claims 7
- 102000039446 nucleic acids Human genes 0.000 claims 7
- 108010035023 4-hydroxybutyryl-CoA dehydratase Proteins 0.000 claims 6
- 101100162204 Aspergillus parasiticus (strain ATCC 56775 / NRRL 5862 / SRRC 143 / SU-1) aflH gene Proteins 0.000 claims 6
- 102000011426 Enoyl-CoA hydratase Human genes 0.000 claims 6
- 108010023922 Enoyl-CoA hydratase Proteins 0.000 claims 6
- 101150031227 GDH2 gene Proteins 0.000 claims 6
- 101150099894 GDHA gene Proteins 0.000 claims 6
- 101150024743 adhA gene Proteins 0.000 claims 6
- 230000001419 dependent effect Effects 0.000 claims 6
- 101150069125 fadB gene Proteins 0.000 claims 6
- 101150092019 fadJ gene Proteins 0.000 claims 6
- ZWEHNKRNPOVVGH-UHFFFAOYSA-N 2-Butanone Chemical compound CCC(C)=O ZWEHNKRNPOVVGH-UHFFFAOYSA-N 0.000 claims 4
- SBRVJFMQKPUAGQ-UHFFFAOYSA-N 2-amino-4-hydroxypentanoic acid Chemical compound CC(O)CC(N)C(O)=O SBRVJFMQKPUAGQ-UHFFFAOYSA-N 0.000 claims 4
- 102100032282 26S proteasome non-ATPase regulatory subunit 14 Human genes 0.000 claims 4
- 102100039358 3-hydroxyacyl-CoA dehydrogenase type-2 Human genes 0.000 claims 4
- HFKQINMYQUXOCH-UHFFFAOYSA-N 4-hydroxy-2-oxopentanoic acid Chemical compound CC(O)CC(=O)C(O)=O HFKQINMYQUXOCH-UHFFFAOYSA-N 0.000 claims 4
- 101100171005 Amycolatopsis orientalis dpgB gene Proteins 0.000 claims 4
- 101710088194 Dehydrogenase Proteins 0.000 claims 4
- 101100243777 Dictyostelium discoideum phbB gene Proteins 0.000 claims 4
- 101150019065 HBD gene Proteins 0.000 claims 4
- 101000590281 Homo sapiens 26S proteasome non-ATPase regulatory subunit 14 Proteins 0.000 claims 4
- 101001035740 Homo sapiens 3-hydroxyacyl-CoA dehydrogenase type-2 Proteins 0.000 claims 4
- 101150007959 Lum gene Proteins 0.000 claims 4
- 101100242684 Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099) panD1 gene Proteins 0.000 claims 4
- 101100276041 Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) ctpD gene Proteins 0.000 claims 4
- 101100028920 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) cfp gene Proteins 0.000 claims 4
- 101100063536 Pseudomonas sp. (strain CF600) dmpH gene Proteins 0.000 claims 4
- 101100498625 Selenomonas ruminantium ldc gene Proteins 0.000 claims 4
- 101100398785 Streptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R) ldhD gene Proteins 0.000 claims 4
- 101100386830 Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) ddh gene Proteins 0.000 claims 4
- SRUCYNCHUFMZIT-UHFFFAOYSA-N acetyl prop-2-enoate Chemical compound CC(=O)OC(=O)C=C SRUCYNCHUFMZIT-UHFFFAOYSA-N 0.000 claims 4
- 101150014383 adhE gene Proteins 0.000 claims 4
- 101150008667 cadA gene Proteins 0.000 claims 4
- 101150063051 hom gene Proteins 0.000 claims 4
- 101150026107 ldh1 gene Proteins 0.000 claims 4
- 101150041530 ldha gene Proteins 0.000 claims 4
- 101150033534 lysA gene Proteins 0.000 claims 4
- 101150080950 mdlC gene Proteins 0.000 claims 4
- 101150001292 padC gene Proteins 0.000 claims 4
- 101150076071 panD gene Proteins 0.000 claims 4
- 101150014006 thrA gene Proteins 0.000 claims 4
- 101150051977 AAT2 gene Proteins 0.000 claims 3
- 101150046224 ABAT gene Proteins 0.000 claims 3
- 101150014733 ASP5 gene Proteins 0.000 claims 3
- 102100033814 Alanine aminotransferase 2 Human genes 0.000 claims 3
- 101100377784 Arabidopsis thaliana ASP2 gene Proteins 0.000 claims 3
- 101100223316 Arabidopsis thaliana GAD2 gene Proteins 0.000 claims 3
- 101100277697 Bacillus subtilis (strain 168) rocG gene Proteins 0.000 claims 3
- 101100174521 Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110) fumC2 gene Proteins 0.000 claims 3
- 101150097247 CRT1 gene Proteins 0.000 claims 3
- 101100335626 Caenorhabditis elegans fum-1 gene Proteins 0.000 claims 3
- 101100067649 Caenorhabditis elegans gta-1 gene Proteins 0.000 claims 3
- 101100385314 Clostridioides difficile crt gene Proteins 0.000 claims 3
- 101100338533 Clostridium aminobutyricum abfD gene Proteins 0.000 claims 3
- 101100322572 Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) adc gene Proteins 0.000 claims 3
- 101100322573 Clostridium botulinum (strain Eklund 17B / Type B) adc gene Proteins 0.000 claims 3
- 101000636215 Crotalus durissus terrificus Crotamine Proteins 0.000 claims 3
- 101100489862 Danio rerio got2a gene Proteins 0.000 claims 3
- 101100335628 Dictyostelium discoideum fumH gene Proteins 0.000 claims 3
- 101100493587 Escherichia coli (strain K12) avtA gene Proteins 0.000 claims 3
- 101100174518 Escherichia coli (strain K12) fumB gene Proteins 0.000 claims 3
- 101100350700 Escherichia coli (strain K12) paaB gene Proteins 0.000 claims 3
- 101100350709 Escherichia coli (strain K12) paaG gene Proteins 0.000 claims 3
- 101100082381 Escherichia coli (strain K12) patA gene Proteins 0.000 claims 3
- 101100246464 Escherichia coli (strain K12) puuE gene Proteins 0.000 claims 3
- 101150094033 GDH1 gene Proteins 0.000 claims 3
- 101150079757 GPT2 gene Proteins 0.000 claims 3
- 108010050375 Glucose 1-Dehydrogenase Proteins 0.000 claims 3
- 108010000445 Glycerate dehydrogenase Proteins 0.000 claims 3
- 101100277701 Halobacterium salinarum gdhX gene Proteins 0.000 claims 3
- 101100120826 Methylorubrum extorquens (strain ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB 9133 / AM1) fumC gene Proteins 0.000 claims 3
- 101100328158 Mus musculus Clmp gene Proteins 0.000 claims 3
- 101100268515 Mus musculus Serpina1b gene Proteins 0.000 claims 3
- 101100392454 Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828) gdh2 gene Proteins 0.000 claims 3
- 101100310885 Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) spuC gene Proteins 0.000 claims 3
- 101100463818 Pseudomonas oleovorans phaC1 gene Proteins 0.000 claims 3
- 101100332697 Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003) fadB1 gene Proteins 0.000 claims 3
- 101100443340 Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) dmdB gene Proteins 0.000 claims 3
- 101100116769 Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) gdhA-2 gene Proteins 0.000 claims 3
- 101100489854 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) AAT2 gene Proteins 0.000 claims 3
- 101100492609 Talaromyces wortmannii astC gene Proteins 0.000 claims 3
- 101100400217 Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) lysN gene Proteins 0.000 claims 3
- 101150004098 UGA1 gene Proteins 0.000 claims 3
- 101100277160 Xenopus laevis odc1-a gene Proteins 0.000 claims 3
- 101150116772 aatA gene Proteins 0.000 claims 3
- 101150006589 adc gene Proteins 0.000 claims 3
- 101150005925 aspC gene Proteins 0.000 claims 3
- 101150056596 azin2 gene Proteins 0.000 claims 3
- 101150100742 dapL gene Proteins 0.000 claims 3
- 101150012368 dmdA gene Proteins 0.000 claims 3
- 101150004244 fumA gene Proteins 0.000 claims 3
- 101150028420 fumC gene Proteins 0.000 claims 3
- 101150116670 gabT gene Proteins 0.000 claims 3
- 108010029645 galactitol 2-dehydrogenase Proteins 0.000 claims 3
- 101150019455 gdh gene Proteins 0.000 claims 3
- 101150098764 gdhA1 gene Proteins 0.000 claims 3
- 101150086595 lat gene Proteins 0.000 claims 3
- 101150056697 nadX gene Proteins 0.000 claims 3
- 101150037784 paaA gene Proteins 0.000 claims 3
- 101150046540 phaA gene Proteins 0.000 claims 3
- 238000000926 separation method Methods 0.000 claims 3
- WWJZWCUNLNYYAU-UHFFFAOYSA-N temephos Chemical compound C1=CC(OP(=S)(OC)OC)=CC=C1SC1=CC=C(OP(=S)(OC)OC)C=C1 WWJZWCUNLNYYAU-UHFFFAOYSA-N 0.000 claims 3
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 claims 2
- 102100034044 All-trans-retinol dehydrogenase [NAD(+)] ADH1B Human genes 0.000 claims 2
- 101710193111 All-trans-retinol dehydrogenase [NAD(+)] ADH4 Proteins 0.000 claims 2
- 101150031273 BDH1 gene Proteins 0.000 claims 2
- 101100098786 Bacillus subtilis (strain 168) tapA gene Proteins 0.000 claims 2
- 101100110009 Caenorhabditis elegans asd-2 gene Proteins 0.000 claims 2
- 101100108227 Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) adhI gene Proteins 0.000 claims 2
- 101100269671 Dictyostelium discoideum alrA gene Proteins 0.000 claims 2
- 101100447155 Escherichia coli (strain K12) fre gene Proteins 0.000 claims 2
- 101100350708 Escherichia coli (strain K12) paaF gene Proteins 0.000 claims 2
- 101100082074 Escherichia coli (strain K12) paaZ gene Proteins 0.000 claims 2
- 101100321116 Escherichia coli (strain K12) yqhD gene Proteins 0.000 claims 2
- 101100236497 Klebsiella aerogenes maoC gene Proteins 0.000 claims 2
- 101100456321 Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2) Msed_0709 gene Proteins 0.000 claims 2
- 101100269700 Mycolicibacterium smegmatis alr gene Proteins 0.000 claims 2
- 101100350716 Pseudomonas putida paaK gene Proteins 0.000 claims 2
- 101100493797 Thauera butanivorans (strain ATCC 43655 / DSM 2080 / JCM 20651 / NBRC 103042 / IAM 12574 / Bu B1211) bdh gene Proteins 0.000 claims 2
- 101100056949 Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W) ansA gene Proteins 0.000 claims 2
- 101150079502 acr1 gene Proteins 0.000 claims 2
- 238000005576 amination reaction Methods 0.000 claims 2
- 101150082095 ansB gene Proteins 0.000 claims 2
- 101150008745 bphG gene Proteins 0.000 claims 2
- 238000004821 distillation Methods 0.000 claims 2
- 101150041588 eutE gene Proteins 0.000 claims 2
- 238000000605 extraction Methods 0.000 claims 2
- 101150004992 fadA gene Proteins 0.000 claims 2
- 101150027774 fadI gene Proteins 0.000 claims 2
- 101150115959 fadR gene Proteins 0.000 claims 2
- 101150056881 mcr gene Proteins 0.000 claims 2
- 101150031436 sucD gene Proteins 0.000 claims 2
- VLSWXZBMRYEYQX-UHFFFAOYSA-N 4-aminobutan-2-one azane Chemical compound N.NCCC(C)=O VLSWXZBMRYEYQX-UHFFFAOYSA-N 0.000 claims 1
- 101100455775 Geobacillus stearothermophilus lysDH gene Proteins 0.000 claims 1
- 101150010646 ODC1 gene Proteins 0.000 claims 1
- 108010065064 acetaldehyde dehydrogenase (acylating) Proteins 0.000 claims 1
- 238000005377 adsorption chromatography Methods 0.000 claims 1
- 238000005119 centrifugation Methods 0.000 claims 1
- 238000002425 crystallisation Methods 0.000 claims 1
- 230000008025 crystallization Effects 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 238000000909 electrodialysis Methods 0.000 claims 1
- 238000001914 filtration Methods 0.000 claims 1
- 239000001963 growth medium Substances 0.000 claims 1
- 238000004255 ion exchange chromatography Methods 0.000 claims 1
- 101150004610 kdd gene Proteins 0.000 claims 1
- 238000000622 liquid--liquid extraction Methods 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000002609 medium Substances 0.000 claims 1
- 239000012528 membrane Substances 0.000 claims 1
- 238000005374 membrane filtration Methods 0.000 claims 1
- 101150064028 ortA gene Proteins 0.000 claims 1
- 101150007368 ortB gene Proteins 0.000 claims 1
- 238000005373 pervaporation Methods 0.000 claims 1
- 238000001223 reverse osmosis Methods 0.000 claims 1
- 238000000638 solvent extraction Methods 0.000 claims 1
- 101150000850 thrC gene Proteins 0.000 claims 1
- 238000000108 ultra-filtration Methods 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2018078301A JP6899793B2 (ja) | 2009-04-30 | 2018-04-16 | １，３−ブタンジオールの産生のための生物 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17447309P | 2009-04-30 | 2009-04-30 | |
| US61/174,473 | 2009-04-30 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012508804A Division JP5876822B2 (ja) | 2009-04-30 | 2010-04-30 | １，３−ブタンジオールの産生のための生物 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018078301A Division JP6899793B2 (ja) | 2009-04-30 | 2018-04-16 | １，３−ブタンジオールの産生のための生物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016063823A JP2016063823A (ja) | 2016-04-28 |
| JP2016063823A5 true JP2016063823A5 (cg-RX-API-DMAC7.html) | 2016-06-16 |
| JP6326398B2 JP6326398B2 (ja) | 2018-05-16 |
Family
ID=43032812
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012508804A Active JP5876822B2 (ja) | 2009-04-30 | 2010-04-30 | １，３−ブタンジオールの産生のための生物 |
| JP2015231313A Active JP6326398B2 (ja) | 2009-04-30 | 2015-11-27 | １，３−ブタンジオールの産生のための生物 |
| JP2018078301A Active JP6899793B2 (ja) | 2009-04-30 | 2018-04-16 | １，３−ブタンジオールの産生のための生物 |
| JP2020104368A Pending JP2020156507A (ja) | 2009-04-30 | 2020-06-17 | １，３−ブタンジオールの産生のための生物 |
| JP2023051610A Pending JP2023082077A (ja) | 2009-04-30 | 2023-03-28 | １，３－ブタンジオールの産生のための生物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012508804A Active JP5876822B2 (ja) | 2009-04-30 | 2010-04-30 | １，３−ブタンジオールの産生のための生物 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018078301A Active JP6899793B2 (ja) | 2009-04-30 | 2018-04-16 | １，３−ブタンジオールの産生のための生物 |
| JP2020104368A Pending JP2020156507A (ja) | 2009-04-30 | 2020-06-17 | １，３−ブタンジオールの産生のための生物 |
| JP2023051610A Pending JP2023082077A (ja) | 2009-04-30 | 2023-03-28 | １，３－ブタンジオールの産生のための生物 |
Country Status (13)
| Country | Link |
|---|---|
| US (5) | US9017983B2 (cg-RX-API-DMAC7.html) |
| EP (6) | EP3865569B1 (cg-RX-API-DMAC7.html) |
| JP (5) | JP5876822B2 (cg-RX-API-DMAC7.html) |
| KR (6) | KR101950944B1 (cg-RX-API-DMAC7.html) |
| CN (2) | CN106119113A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2010242789B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI1013426A2 (cg-RX-API-DMAC7.html) |
| CA (2) | CA3042565A1 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2593117T3 (cg-RX-API-DMAC7.html) |
| LT (1) | LT2424975T (cg-RX-API-DMAC7.html) |
| MY (1) | MY176050A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2010127319A2 (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA201107806B (cg-RX-API-DMAC7.html) |
Families Citing this family (70)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0913901A2 (pt) | 2008-06-17 | 2016-12-13 | Genomatica Inc | micro-organismos e métodos para a biossíntese de fumarato, malato e acrilato |
| KR20110097951A (ko) | 2008-12-16 | 2011-08-31 | 게노마티카 인코포레이티드 | 합성가스와 다른 탄소원을 유용 제품으로 전환시키기 위한 미생물 및 방법 |
| WO2010127319A2 (en) * | 2009-04-30 | 2010-11-04 | Genomatica, Inc. | Organisms for the production of 1,3-butanediol |
| US8420375B2 (en) | 2009-06-10 | 2013-04-16 | Genomatica, Inc. | Microorganisms and methods for carbon-efficient biosynthesis of MEK and 2-butanol |
| WO2011052718A1 (ja) * | 2009-10-30 | 2011-05-05 | ダイセル化学工業株式会社 | １，３－ブタンジオール生産機能を付与された遺伝子組換え微生物及びその利用 |
| EP2510102A4 (en) | 2009-12-10 | 2014-01-22 | Genomatica Inc | METHODS AND ORGANIZATIONS FOR THE CONVERSION OF SYNTHESIS GAS OR OTHER CARBONACEOUS GAS SOURCES AND METHANOL TO 1,3-BUTANEDIOL |
| US8445244B2 (en) | 2010-02-23 | 2013-05-21 | Genomatica, Inc. | Methods for increasing product yields |
| AU2011248182A1 (en) * | 2010-05-05 | 2012-11-15 | Genomatica, Inc. | Microorganisms and methods for the biosynthesis of butadiene |
| CN102533870B (zh) * | 2010-12-23 | 2014-04-16 | 中国科学院青岛生物能源与过程研究所 | 一种生物法合成异戊二烯的方法、酶系统和重组细胞及其应用 |
| MY162964A (en) * | 2011-02-02 | 2017-07-31 | Genomatica Inc | Microorganisms and methods for the biosynthesis of butadiene |
| US9169486B2 (en) | 2011-06-22 | 2015-10-27 | Genomatica, Inc. | Microorganisms for producing butadiene and methods related thereto |
| WO2012177619A2 (en) | 2011-06-22 | 2012-12-27 | Genomatica, Inc. | Microorganisms for producing 1,3-butanediol and methods related thereto |
| WO2013028519A1 (en) * | 2011-08-19 | 2013-02-28 | Genomatica, Inc. | Microorganisms and methods for producing 2,4-pentadienoate, butadiene, propylene, 1,3-butanediol and related alcohols |
| EP2850180A1 (en) | 2012-05-18 | 2015-03-25 | Novozymes A/S | Bacterial mutants with improved transformation efficiency |
| WO2014036140A2 (en) * | 2012-08-28 | 2014-03-06 | Braskem S/A Ap 09 | Methods for production of a terpene and a co-product |
| BR112015006107A2 (pt) * | 2012-09-24 | 2017-08-22 | Showa Denko Kk | Método para produzir um butanodiol |
| EP2899273A4 (en) | 2012-09-24 | 2016-03-02 | Showa Denko Kk | GEN, MICROORGANISM, CONVERSION METHOD AND METHOD OF MANUFACTURE |
| JP6012371B2 (ja) * | 2012-09-27 | 2016-10-25 | 株式会社日本触媒 | ４−ヒドロキシ−２−ブタノンまたはブタノールの製造方法 |
| US20150218567A1 (en) | 2012-09-27 | 2015-08-06 | Novozymes A/S | Bacterial Mutants with Improved Transformation Efficiency |
| WO2014087921A1 (ja) | 2012-12-05 | 2014-06-12 | 昭和電工株式会社 | １，４－ブタンジオールの製造方法、微生物及び遺伝子 |
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