|
WO2011130491A2
(en)
|
2010-04-14 |
2011-10-20 |
Roger Williams Medical Center |
Methods and compositions for treating hiv
|
|
US10426740B1
(en)
|
2010-08-18 |
2019-10-01 |
Avm Biotechnology, Llc |
Compositions and methods to inhibit stem cell and progenitor cell binding to lymphoid tissue and for regenerating germinal centers in lymphatic tissues
|
|
JP2014509841A
(ja)
*
|
2011-01-18 |
2014-04-24 |
ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア |
癌を治療するための組成物および方法
|
|
SG10201806573TA
(en)
|
2012-05-25 |
2018-09-27 |
Cellectis |
Methods for engineering allogeneic and immunosuppressive resistant t cell for immunotherapy
|
|
WO2014055442A2
(en)
*
|
2012-10-01 |
2014-04-10 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for targeting stromal cells for the treatment of cancer
|
|
US10117896B2
(en)
*
|
2012-10-05 |
2018-11-06 |
The Trustees Of The University Of Pennsylvania |
Use of a trans-signaling approach in chimeric antigen receptors
|
|
US9598489B2
(en)
|
2012-10-05 |
2017-03-21 |
The Trustees Of The Univeristy Of Pennsylvania |
Human alpha-folate receptor chimeric antigen receptor
|
|
WO2014059173A2
(en)
|
2012-10-10 |
2014-04-17 |
Sangamo Biosciences, Inc. |
T cell modifying compounds and uses thereof
|
|
EP2934532B1
(en)
|
2012-12-20 |
2019-10-23 |
Purdue Research Foundation |
Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics
|
|
AU2013204922B2
(en)
|
2012-12-20 |
2015-05-14 |
Celgene Corporation |
Chimeric antigen receptors
|
|
JO3529B1
(ar)
|
2013-02-08 |
2020-07-05 |
Amgen Res Munich Gmbh |
مضاد التصاق خلايا الدم البيض من أجل التخفيف من الاثار السلبية الممكنة الناتجة عن مجالات ارتباط cd3- المحدد
|
|
IL305629A
(en)
|
2013-02-15 |
2023-11-01 |
Univ California |
Chimeric antigen receptor and methods of using it
|
|
WO2014130635A1
(en)
|
2013-02-20 |
2014-08-28 |
Novartis Ag |
Effective targeting of primary human leukemia using anti-cd123 chimeric antigen receptor engineered t cells
|
|
SG11201505896YA
(en)
|
2013-02-20 |
2015-09-29 |
Novartis Ag |
Treatment of cancer using humanized anti-egfrviii chimeric antigen receptor
|
|
ES2769574T3
(es)
|
2013-03-15 |
2020-06-26 |
Michael C Milone |
Reconocimiento de células citotóxicas con receptores quiméricos para inmunoterapia adoptiva
|
|
EP2970372B1
(en)
|
2013-03-15 |
2020-09-30 |
Celgene Corporation |
Modified t lymphocytes
|
|
UY35468A
(es)
|
2013-03-16 |
2014-10-31 |
Novartis Ag |
Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19
|
|
US11077144B2
(en)
|
2013-05-13 |
2021-08-03 |
Cellectis |
CD19 specific chimeric antigen receptor and uses thereof
|
|
SI2997141T1
(sl)
*
|
2013-05-13 |
2023-04-28 |
Cellectis |
CD19 specifični himerni antigenski receptor in njegova uporaba
|
|
AU2014324102B2
(en)
*
|
2013-09-23 |
2021-01-28 |
Wilson Wolf Manufacturing, LLC |
Improved methods of genetically modifying animal cells
|
|
CN103589742A
(zh)
*
|
2013-11-07 |
2014-02-19 |
申峰 |
嵌合体抗原受体胞内段的基因及其编码蛋白
|
|
ES2918501T3
(es)
|
2013-12-19 |
2022-07-18 |
Novartis Ag |
Receptores de antígenos quiméricos de mesotelina humana y usos de los mismos
|
|
WO2015090229A1
(en)
|
2013-12-20 |
2015-06-25 |
Novartis Ag |
Regulatable chimeric antigen receptor
|
|
WO2015092024A2
(en)
*
|
2013-12-20 |
2015-06-25 |
Cellectis |
Method of engineering multi-input signal sensitive t cell for immunotherapy
|
|
EP3097117B1
(en)
|
2014-01-21 |
2023-10-04 |
Novartis Ag |
Enhanced antigen presenting ability of car t cells by co-introduction of costimulatory molecules
|
|
DK3105335T3
(da)
*
|
2014-02-14 |
2020-01-13 |
Univ Texas |
Kimære antigenreceptorer og fremgangsmåder til fremstilling heraf
|
|
GB201405845D0
(en)
*
|
2014-04-01 |
2014-05-14 |
Ucl Business Plc |
Signalling system
|
|
SG10202109752XA
(en)
|
2014-04-07 |
2021-10-28 |
Novartis Ag |
Treatment of cancer using anti-cd19 chimeric antigen receptor
|
|
SG10201808811QA
(en)
*
|
2014-04-10 |
2018-11-29 |
Seattle Childrens Hospital Dba Seattle Childrens Res Inst |
Method and compositions for cellular immunotherapy
|
|
US20170158749A1
(en)
*
|
2014-04-23 |
2017-06-08 |
Board Of Regents, The University Of Texas System |
Chimeric antigen receptors (car) and methods for making and using the same
|
|
WO2015164759A2
(en)
|
2014-04-25 |
2015-10-29 |
Bluebird Bio, Inc. |
Mnd promoter chimeric antigen receptors
|
|
CN106456670B
(zh)
|
2014-04-25 |
2020-01-07 |
蓝鸟生物公司 |
制备过继性细胞疗法的改善方法
|
|
EP3166968B1
(en)
*
|
2014-05-02 |
2021-09-22 |
The Trustees of the University of Pennsylvania |
Compositions and methods of chimeric autoantibody receptor t cells
|
|
RS61406B1
(sr)
*
|
2014-06-06 |
2021-03-31 |
Bluebird Bio Inc |
Poboljšane kompozicije t ćelija
|
|
BR112017000939A2
(pt)
|
2014-07-21 |
2017-11-14 |
Novartis Ag |
tratamento de câncer usando um receptor antigênico quimérico de cll-1
|
|
AU2015292744C1
(en)
|
2014-07-21 |
2021-01-21 |
Novartis Ag |
Treatment of cancer using humanized anti-BCMA chimeric antigen receptor
|
|
JP6831777B2
(ja)
|
2014-07-21 |
2021-02-17 |
ノバルティス アーゲー |
Cd33キメラ抗原受容体を使用する癌の処置
|
|
WO2016014553A1
(en)
|
2014-07-21 |
2016-01-28 |
Novartis Ag |
Sortase synthesized chimeric antigen receptors
|
|
EP3172231B1
(en)
|
2014-07-24 |
2021-05-05 |
Bluebird Bio, Inc. |
Bcma chimeric antigen receptors
|
|
RU2017102769A
(ru)
*
|
2014-07-29 |
2018-08-28 |
Пфайзер Инк. |
EGFRvIII СПЕЦИФИЧЕСКИЕ ХИМЕРНЫЕ АНТИГЕННЫЕ РЕЦЕПТОРЫ ДЛЯ ИММУНОТЕРАПИИ РАКА
|
|
EP3712171A1
(en)
|
2014-08-19 |
2020-09-23 |
Novartis AG |
Treatment of cancer using a cd123 chimeric antigen receptor
|
|
DK3186284T3
(da)
*
|
2014-08-28 |
2022-05-09 |
Bioatla Inc |
Betinget aktive kimæriske antigenreceptorer til modificerede t-celler
|
|
US11111288B2
(en)
|
2014-08-28 |
2021-09-07 |
Bioatla, Inc. |
Conditionally active chimeric antigen receptors for modified t-cells
|
|
US10577417B2
(en)
|
2014-09-17 |
2020-03-03 |
Novartis Ag |
Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
|
|
AU2015330898B2
(en)
|
2014-10-08 |
2022-03-10 |
Novartis Ag |
Biomarkers predictive of therapeutic responsiveness to chimeric antigen receptor therapy and uses thereof
|
|
JP6740234B2
(ja)
*
|
2014-11-05 |
2020-08-12 |
ジュノー セラピューティクス インコーポレイテッド |
形質導入および細胞プロセシングのための方法
|
|
US10383929B2
(en)
|
2014-12-12 |
2019-08-20 |
Bluebird Bio, Inc. |
BCMA chimeric antigen receptors
|
|
RU2017125531A
(ru)
*
|
2014-12-19 |
2019-01-21 |
Дана-Фарбер Кэнсер Инститьют, Инк. |
Химерные антигенные рецепторы и способы их применения
|
|
RU2751362C2
(ru)
|
2014-12-29 |
2021-07-13 |
Новартис Аг |
Способы получения экспрессирующих химерный антигенный рецептор клеток
|
|
US11459390B2
(en)
|
2015-01-16 |
2022-10-04 |
Novartis Ag |
Phosphoglycerate kinase 1 (PGK) promoters and methods of use for expressing chimeric antigen receptor
|
|
EP3250602A1
(en)
|
2015-01-26 |
2017-12-06 |
Cellectis |
T cell receptor knock out engineered immune cells, endowed with chimeric antigen receptors binding to cd123 for the treatment of relapsed/refractory acute myeloid lymphoma or blastic plasmacytoid dendritic cell neoplasm
|
|
WO2016126608A1
(en)
*
|
2015-02-02 |
2016-08-11 |
Novartis Ag |
Car-expressing cells against multiple tumor antigens and uses thereof
|
|
EP3262166A4
(en)
|
2015-02-24 |
2018-08-15 |
The Regents of The University of California |
Binding-triggered transcriptional switches and methods of use thereof
|
|
BR112017020750A2
(en)
|
2015-03-27 |
2018-06-26 |
President And Fellows Of Harvard College |
modified t-cells and methods of producing and using them
|
|
PL3280729T3
(pl)
|
2015-04-08 |
2022-08-22 |
Novartis Ag |
Terapie cd20, terapie cd22 i terapie skojarzone komórką eksprymującą chimeryczny receptor antygenowy (car) cd19
|
|
WO2016168595A1
(en)
|
2015-04-17 |
2016-10-20 |
Barrett David Maxwell |
Methods for improving the efficacy and expansion of chimeric antigen receptor-expressing cells
|
|
WO2016172583A1
(en)
|
2015-04-23 |
2016-10-27 |
Novartis Ag |
Treatment of cancer using chimeric antigen receptor and protein kinase a blocker
|
|
DK3294893T5
(da)
*
|
2015-05-13 |
2024-10-07 |
Csl Behring Gene Therapy Inc |
Bioproduktion af lentivirale vektorer
|
|
EP3770168A1
(en)
|
2015-05-18 |
2021-01-27 |
TCR2 Therapeutics Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
|
KR20230005428A
(ko)
|
2015-05-28 |
2023-01-09 |
카이트 파마 인코포레이티드 |
T 세포 요법을 위한 진단 방법
|
|
KR102349677B1
(ko)
|
2015-05-28 |
2022-01-12 |
카이트 파마 인코포레이티드 |
T 세포 요법을 위해 환자를 컨디셔닝하는 방법
|
|
CA2992122A1
(en)
*
|
2015-07-16 |
2017-01-19 |
Prospect CharterCare RWMC, LLC d/b/a Roger Williams Medical Center |
Compositions and methods for treating peritoneal cancers
|
|
US10829735B2
(en)
|
2015-07-21 |
2020-11-10 |
The Trustees Of The University Of Pennsylvania |
Methods for improving the efficacy and expansion of immune cells
|
|
US11667691B2
(en)
|
2015-08-07 |
2023-06-06 |
Novartis Ag |
Treatment of cancer using chimeric CD3 receptor proteins
|
|
MX2018001568A
(es)
|
2015-08-07 |
2019-04-25 |
Seattle Children´S Hospital Dba Seattle Children´S Res Institute |
Celulas t biespecificas de receptor quimerico de antigeno (car) para focalizacion a tumores solidos.
|
|
WO2017040930A2
(en)
|
2015-09-03 |
2017-03-09 |
The Trustees Of The University Of Pennsylvania |
Biomarkers predictive of cytokine release syndrome
|
|
IL292504B2
(en)
|
2015-10-20 |
2024-01-01 |
Kite Pharma Inc |
-methods of preparing t cells for t cell therapy
|
|
JP7092662B2
(ja)
*
|
2015-10-30 |
2022-06-28 |
チルドレンズ ナショナル メディカル センター |
ナイーブt細胞集団からのhpv抗原特異的t細胞の生成
|
|
CN105331585A
(zh)
|
2015-11-13 |
2016-02-17 |
科济生物医药(上海)有限公司 |
携带pd-l1阻断剂的嵌合抗原受体修饰的免疫效应细胞
|
|
AU2016355323B2
(en)
*
|
2015-11-19 |
2021-03-04 |
Novartis Ag |
Buffers for stabilization of lentiviral preparations
|
|
EP3377523A4
(en)
*
|
2015-11-19 |
2019-06-19 |
The Regents of The University of California |
CONDITIONALLY REPRIMATABLE IMMUNOCELL RECEPTORS AND METHOD FOR USE THEREOF
|
|
JP6976960B2
(ja)
|
2015-11-27 |
2021-12-08 |
カーサリクス プロプライエタリー リミテッド |
遺伝子改変された細胞およびその使用
|
|
WO2017093969A1
(en)
|
2015-12-04 |
2017-06-08 |
Novartis Ag |
Compositions and methods for immunooncology
|
|
WO2017099712A1
(en)
|
2015-12-07 |
2017-06-15 |
Bluebird Bio, Inc. |
Improved t cell compositions
|
|
GB201522097D0
(en)
|
2015-12-15 |
2016-01-27 |
Cellular Therapeutics Ltd |
Cells
|
|
PT3393504T
(pt)
|
2015-12-22 |
2025-12-30 |
Novartis Ag |
Recetor de antigénio quimérico (car) de mesotelina e anticorpo contra o inibidor de pd-l1 para utilização combinada em terapia anticancerígena
|
|
MX2018008416A
(es)
|
2016-01-08 |
2019-11-11 |
Univ California |
Polipéptidos heterodímericos condicionalmente activos y métodos para su uso.
|
|
EP3432924A1
(en)
|
2016-03-23 |
2019-01-30 |
Novartis AG |
Cell secreted minibodies and uses thereof
|
|
SG10201912519VA
(en)
|
2016-04-01 |
2020-02-27 |
Kite Pharma Inc |
Chimeric receptors and methods of use thereof
|
|
NZ746700A
(en)
|
2016-04-01 |
2023-04-28 |
Kite Pharma Inc |
Bcma binding molecules and methods of use thereof
|
|
KR102427334B1
(ko)
|
2016-04-01 |
2022-08-03 |
카이트 파마 인코포레이티드 |
키메라 항원 및 t 세포 수용체 및 사용 방법
|
|
CA3019835A1
(en)
|
2016-04-08 |
2017-10-12 |
Purdue Research Foundation |
Methods and compositions for car t cell therapy
|
|
WO2017180587A2
(en)
|
2016-04-11 |
2017-10-19 |
Obsidian Therapeutics, Inc. |
Regulated biocircuit systems
|
|
AU2017248830B2
(en)
|
2016-04-15 |
2023-03-09 |
Alpine Immune Sciences, Inc. |
CD80 variant immunomodulatory proteins and uses thereof
|
|
CN109414512A
(zh)
|
2016-04-22 |
2019-03-01 |
科济生物医药(上海)有限公司 |
用于细胞免疫疗法的组合物和方法
|
|
CN118165113B
(zh)
*
|
2016-04-26 |
2025-10-28 |
恺兴生命科技(上海)有限公司 |
一种改善免疫应答细胞功能的方法
|
|
EP4122958A1
(en)
|
2016-05-13 |
2023-01-25 |
BioAtla, Inc. |
Anti-ror2 antibodies, antibody fragments, their immunoconjugates and uses thereof
|
|
EP4650005A3
(en)
|
2016-07-15 |
2026-01-28 |
Viracta Subsidiary, Inc. |
Histone deacetylase inhibitors for use in immunotherapy
|
|
WO2018022945A1
(en)
|
2016-07-28 |
2018-02-01 |
Alpine Immune Sciences, Inc. |
Cd112 variant immunomodulatory proteins and uses thereof
|
|
US11471488B2
(en)
|
2016-07-28 |
2022-10-18 |
Alpine Immune Sciences, Inc. |
CD155 variant immunomodulatory proteins and uses thereof
|
|
EP3491013A1
(en)
|
2016-07-28 |
2019-06-05 |
Alpine Immune Sciences, Inc. |
Cd155 variant immunomodulatory proteins and uses thereof
|
|
WO2018026953A1
(en)
|
2016-08-02 |
2018-02-08 |
TCR2 Therapeutics Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
|
WO2018057585A1
(en)
|
2016-09-21 |
2018-03-29 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Chimeric antigen receptor (car) that targets chemokine receptor ccr4 and its use
|
|
BR112019007100A2
(pt)
|
2016-10-07 |
2019-06-25 |
Tcr2 Therapeutics Inc |
composições e métodos para reprogramação de receptores de célula t com o uso de proteínas de fusão
|
|
JP7467117B2
(ja)
|
2016-10-07 |
2024-04-15 |
ノバルティス アーゲー |
癌の治療のためのキメラ抗原受容体
|
|
CN109983027A
(zh)
|
2016-10-20 |
2019-07-05 |
细胞基因公司 |
基于cereblon的可异二聚化嵌合抗原受体
|
|
EP3872180A1
(en)
|
2016-10-20 |
2021-09-01 |
Alpine Immune Sciences, Inc. |
Secretable variant immunomodulatory proteins and engineered cell therapy
|
|
MX2019005277A
(es)
|
2016-11-04 |
2019-09-27 |
Bluebird Bio Inc |
Composiciones de celulas t con car anti-bcma.
|
|
CN110177803A
(zh)
|
2016-11-22 |
2019-08-27 |
T细胞受体治疗公司 |
用于使用融合蛋白进行tcr重新编程的组合物和方法
|
|
WO2018111763A1
(en)
|
2016-12-12 |
2018-06-21 |
Seattle Children's Hospital (dba Seattle Children's Research Institute) |
Chimeric transcription factor variants with augmented sensitivity to drug ligand induction of transgene expression in mammalian cells
|
|
GB201700621D0
(en)
|
2017-01-13 |
2017-03-01 |
Guest Ryan Dominic |
Method,device and kit for the aseptic isolation,enrichment and stabilsation of cells from mammalian solid tissue
|
|
US11535662B2
(en)
|
2017-01-26 |
2022-12-27 |
Novartis Ag |
CD28 compositions and methods for chimeric antigen receptor therapy
|
|
CN106749681A
(zh)
*
|
2017-02-10 |
2017-05-31 |
河南大学淮河医院 |
靶向人FRα的基因工程化NKT细胞及其制备方法和应用
|
|
EP3583129B1
(en)
|
2017-02-14 |
2021-11-03 |
Kite Pharma, Inc. |
Cd70 binding molecules and methods of use thereof
|
|
CN110582288B
(zh)
|
2017-02-28 |
2024-09-20 |
恩多塞特公司 |
用于car t细胞疗法的组合物和方法
|
|
WO2018169922A2
(en)
|
2017-03-13 |
2018-09-20 |
Kite Pharma, Inc. |
Chimeric antigen receptors for melanoma and uses thereof
|
|
JP2020511144A
(ja)
|
2017-03-16 |
2020-04-16 |
アルパイン イミューン サイエンシズ インコーポレイテッド |
Pd−l2バリアント免疫調節タンパク質及びその使用
|
|
FI3596116T3
(fi)
|
2017-03-16 |
2023-11-09 |
Alpine Immune Sciences Inc |
Immunomodulatorisia pd-l1-varianttiproteiineja ja niiden käyttöjä
|
|
MX2019010887A
(es)
|
2017-03-16 |
2019-10-15 |
Alpine Immune Sciences Inc |
Proteinas inmunomoduladoras de cb80 variante y usos de estas.
|
|
KR20190130608A
(ko)
|
2017-03-22 |
2019-11-22 |
노파르티스 아게 |
면역종양학을 위한 조성물 및 방법
|
|
SG11201908784TA
(en)
*
|
2017-03-27 |
2019-10-30 |
Hoffmann La Roche |
Improved antigen binding receptor formats
|
|
CN110475571B
(zh)
|
2017-04-01 |
2023-04-04 |
Avm生物技术有限责任公司 |
细胞免疫疗法前细胞毒性预调理的替代
|
|
KR20190130024A
(ko)
|
2017-04-03 |
2019-11-20 |
카이트 파마 인코포레이티드 |
최적화된 다기능 t 세포를 포함하는 키메라 수용체 t 세포를 사용하는 치료
|
|
JP2020517259A
(ja)
|
2017-04-19 |
2020-06-18 |
ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム |
操作された抗原受容体を発現する免疫細胞
|
|
BR102018008260A2
(pt)
|
2017-04-24 |
2020-04-28 |
Kite Pharma, Inc. |
domínios de ligação ao antígeno humanizado e métodos de uso
|
|
US11778994B2
(en)
|
2017-05-12 |
2023-10-10 |
The Jackson Laboratory |
NSG mice lacking MHC class I and class II
|
|
ES3000510T3
(en)
|
2017-06-09 |
2025-02-28 |
Providence Health & Services Oregon |
Tumor-infiltrating t-cells for use in the treatment of cancer
|
|
AU2018292181B2
(en)
|
2017-06-30 |
2025-04-10 |
Cellectis |
Cellular immunotherapy for repetitive administration
|
|
KR102755437B1
(ko)
*
|
2017-08-09 |
2025-01-20 |
주노 쎄러퓨티크스 인코퍼레이티드 |
유전자 조작된 세포 조성물 및 관련 조성물의 제조 방법
|
|
CN111315403A
(zh)
*
|
2017-09-15 |
2020-06-19 |
凯德药业股份有限公司 |
用于进行具有监管链和身份链生物样品跟踪的患者特异性免疫疗法规程的方法和系统
|
|
CA3076337A1
(en)
|
2017-09-19 |
2019-03-28 |
Massachusetts Institute Of Technology |
Compositions for chimeric antigen receptor t cell therapy and uses thereof
|
|
EP3684816B1
(en)
|
2017-09-22 |
2024-05-29 |
Kite Pharma, Inc. |
Chimeric polypeptides and uses thereof
|
|
EP3694870A1
(en)
|
2017-10-10 |
2020-08-19 |
Alpine Immune Sciences, Inc. |
Ctla-4 variant immunomodulatory proteins and uses thereof
|
|
EP3697500A1
(en)
|
2017-10-18 |
2020-08-26 |
Kite Pharma, Inc. |
Methods of administering chimeric antigen receptor immunotherapy
|
|
US11712026B2
(en)
|
2017-10-18 |
2023-08-01 |
The Jackson Laboratory |
Murine-MHC-deficient HLA-transgenic nod-mouse models for T1D therapy development
|
|
SG11202003415XA
(en)
|
2017-10-18 |
2020-05-28 |
Novartis Ag |
Compositions and methods for selective protein degradation
|
|
JP7282760B2
(ja)
|
2017-10-18 |
2023-05-29 |
アルパイン イミューン サイエンシズ インコーポレイテッド |
バリアントicosリガンド免疫調節タンパク質ならびに関連する組成物および方法
|
|
US11802163B2
(en)
|
2017-11-10 |
2023-10-31 |
The U.S.A., As Represented By The Secretary, Department Of Health And Human Services |
Chimeric antigen receptors targeting glypican-3 or mesothelin
|
|
WO2019099707A1
(en)
|
2017-11-16 |
2019-05-23 |
Kite Pharma, Inc |
Modified chimeric antigen receptors and methods of use
|
|
GB201721833D0
(en)
*
|
2017-12-22 |
2018-02-07 |
Cancer Research Tech Ltd |
Fusion proteins
|
|
SG11202006148UA
(en)
|
2018-01-03 |
2020-07-29 |
Alpine Immune Sciences Inc |
Multi-domain immunomodulatory proteins and methods of use thereof
|
|
CN111867619A
(zh)
|
2018-01-03 |
2020-10-30 |
曲生物制品公司 |
过继性细胞治疗的先天寻靶
|
|
WO2019136432A1
(en)
|
2018-01-08 |
2019-07-11 |
Novartis Ag |
Immune-enhancing rnas for combination with chimeric antigen receptor therapy
|
|
AU2019206724A1
(en)
|
2018-01-15 |
2020-07-16 |
Kite Pharma, Inc. |
Methods of administering chimeric antigen receptor immunotherapy in combination with 4-1BB agonist
|
|
WO2019144095A1
(en)
|
2018-01-22 |
2019-07-25 |
Seattle Children's Hospital (dba Seattle Children's Research Institute) |
Methods of use for car t cells
|
|
CA3090793C
(en)
|
2018-02-16 |
2024-10-08 |
Kite Pharma, Inc. |
MODIFIED MULTIPOTENTED STEM CELLS, AND METHODS OF PREPARATION AND USE
|
|
WO2019165121A1
(en)
|
2018-02-21 |
2019-08-29 |
Board Of Regents, The University Of Texas System |
Methods for activation and expansion of natural killer cells and uses therof
|
|
JP7568224B2
(ja)
|
2018-02-23 |
2024-10-16 |
エンドサイト・インコーポレイテッド |
Car t細胞療法のための配列決定法
|
|
KR20200130709A
(ko)
|
2018-03-06 |
2020-11-19 |
더 트러스티스 오브 더 유니버시티 오브 펜실바니아 |
전립선-특이 막 항원 car 및 이의 사용 방법
|
|
EP3765521A4
(en)
|
2018-03-13 |
2022-03-23 |
Phanes Therapeutics, Inc. |
ANTI-FOLATE RECEPTOR-1 ANTIBODIES AND USES THEREOF
|
|
DE102018108612A1
(de)
|
2018-03-21 |
2019-09-26 |
Immatics US, Inc. |
Verfahren zur erhöhung der persistenz von adoptiv infundierten t-zellen
|
|
CN119656304A
(zh)
|
2018-04-12 |
2025-03-21 |
凯德药业股份有限公司 |
使用肿瘤微环境的特征的嵌合受体t细胞治疗
|
|
US10869888B2
(en)
|
2018-04-17 |
2020-12-22 |
Innovative Cellular Therapeutics CO., LTD. |
Modified cell expansion and uses thereof
|
|
KR102734592B1
(ko)
|
2018-06-01 |
2024-11-27 |
카이트 파마 인코포레이티드 |
키메라 항원 수용체 t 세포 요법
|
|
MX421685B
(es)
|
2018-06-05 |
2025-03-14 |
Univ Pennsylvania |
Composiciones y metodos de celulas del receptor de autoanticuerpos quimericos de quinasa especifica del musculo
|
|
US20220403001A1
(en)
|
2018-06-12 |
2022-12-22 |
Obsidian Therapeutics, Inc. |
Pde5 derived regulatory constructs and methods of use in immunotherapy
|
|
IL279367B2
(en)
|
2018-06-13 |
2026-05-01 |
Novartis Ag |
BCMA chimeric antigen receptors and their uses
|
|
WO2019241758A1
(en)
|
2018-06-15 |
2019-12-19 |
Alpine Immune Sciences, Inc. |
Pd-1 variant immunomodulatory proteins and uses thereof
|
|
WO2020005837A1
(en)
*
|
2018-06-25 |
2020-01-02 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods of nkg2d chimeric antigen receptor t cells for controlling triple-negative breast cancer
|
|
JP7623939B2
(ja)
*
|
2018-07-09 |
2025-01-29 |
マルチチュード インコーポレーテッド |
葉酸受容体アルファに特異的な抗体
|
|
AU2019314452B2
(en)
|
2018-08-02 |
2022-12-08 |
Kite Pharma, Inc |
Chimeric antigen receptor therapy T cell expansion kinetics and uses thereof
|
|
CN110819703A
(zh)
*
|
2018-08-07 |
2020-02-21 |
上海恒润达生生物科技有限公司 |
一种评估cart细胞安全性的方法
|
|
US12240915B2
(en)
|
2018-08-30 |
2025-03-04 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Chimeric antigen receptor cells for treating solid tumor
|
|
SI3844267T1
(sl)
|
2018-08-31 |
2025-10-30 |
Novartis Ag |
Postopki izdelave celic, ki izražajo receptorje himernega antigena
|
|
US11866494B2
(en)
*
|
2018-08-31 |
2024-01-09 |
Innovative Cellular Therapeutics Holdings, Ltd. |
CAR T therapy through uses of co-stimulation
|
|
CN113544144A
(zh)
|
2018-09-19 |
2021-10-22 |
高山免疫科学股份有限公司 |
变体cd80融合蛋白和相关构建体的方法和用途
|
|
SG11202100935TA
(en)
|
2018-09-28 |
2021-02-25 |
Massachusetts Inst Technology |
Collagen-localized immunomodulatory molecules and methods thereof
|
|
EP3488851A1
(en)
|
2018-10-03 |
2019-05-29 |
AVM Biotechnology, LLC |
Immunoablative therapies
|
|
EP3864051A4
(en)
*
|
2018-10-10 |
2022-11-23 |
Zymeworks Inc. |
ANTIBODY CONSTRUCTS THAT BIND 4-1BB AND TUMOR-ASSOCIATED ANTIGENS AND THEIR USES
|
|
CN111197032A
(zh)
*
|
2018-11-16 |
2020-05-26 |
上海斯丹赛生物技术有限公司 |
嵌合抗原受体细胞分泌治疗剂
|
|
US20220000921A1
(en)
*
|
2018-11-20 |
2022-01-06 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Modified Cell Expressing Therapeutic Agent and Uses thereof
|
|
US10918667B2
(en)
|
2018-11-20 |
2021-02-16 |
Innovative Cellular Therapeutics CO., LTD. |
Modified cell expressing therapeutic agent and uses thereof
|
|
EP3887978A4
(en)
|
2018-11-29 |
2022-08-17 |
Vineti Inc. |
CENTRALIZED AND DECENTRALIZED CUSTOMIZED MEDICATION PLATFORM
|
|
WO2020123716A1
(en)
|
2018-12-11 |
2020-06-18 |
Obsidian Therapeutics, Inc. |
Membrane bound il12 compositions and methods for tunable regulation
|
|
KR20250116790A
(ko)
|
2018-12-12 |
2025-08-01 |
카이트 파마 인코포레이티드 |
키메라 항원 수용체 및 car-t 세포 및 사용 방법
|
|
CN109796535B
(zh)
*
|
2019-01-30 |
2022-11-15 |
重庆福美干细胞生物科技发展有限公司 |
靶向叶酸受体α的嵌合抗原受体及其在制备预防或治疗恶性肿瘤药物中的用途
|
|
US11321652B1
(en)
|
2019-02-20 |
2022-05-03 |
Vineti Inc. |
Smart label devices, systems, and methods
|
|
BR112021017744A2
(pt)
|
2019-03-08 |
2021-11-16 |
Obsidian Therapeutics Inc |
Composições e métodos de cd40l para regulação ajustável
|
|
TW202042824A
(zh)
|
2019-03-27 |
2020-12-01 |
賓夕法尼亞大學董事會 |
Tn-MUC1嵌合抗原受體(CAR)T細胞療法
|
|
CN114206346A
(zh)
|
2019-05-03 |
2022-03-18 |
凯德药业股份有限公司 |
施用嵌合抗原受体免疫疗法的方法
|
|
CN121204097A
(zh)
*
|
2019-05-13 |
2025-12-26 |
宾夕法尼亚大学董事会 |
乙酰胆碱受体嵌合自身抗体受体细胞的组合物和方法
|
|
WO2020234632A1
(en)
|
2019-05-23 |
2020-11-26 |
Ichorlabs, D.O.O |
Method for removal of nucleic acids impurities from liquid composition comprising genetically engineered particles or proteins
|
|
CA3140668A1
(en)
|
2019-06-12 |
2020-12-17 |
Obsidian Therapeutics, Inc. |
Ca2 compositions and methods for tunable regulation
|
|
WO2020252404A1
(en)
|
2019-06-12 |
2020-12-17 |
Obsidian Therapeutics, Inc. |
Ca2 compositions and methods for tunable regulation
|
|
CN114391021B
(zh)
|
2019-06-21 |
2026-01-16 |
凯德药业股份有限公司 |
TGF-β受体和使用方法
|
|
JP2022538974A
(ja)
|
2019-06-26 |
2022-09-07 |
マサチューセッツ インスチテュート オブ テクノロジー |
免疫調節融合タンパク質-金属水酸化物錯体およびその方法
|
|
GB201909573D0
(en)
|
2019-07-03 |
2019-08-14 |
Cancer Research Tech Ltd |
Modulation of T cell cytotoxicity and related therapy
|
|
US12702708B2
(en)
|
2019-08-21 |
2026-08-11 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Presenting cell and use thereof in cell therapy
|
|
WO2021046134A1
(en)
|
2019-09-03 |
2021-03-11 |
Allogene Therapeutics, Inc. |
Methods of preparing t cells for t cell therapy
|
|
WO2021061648A1
(en)
|
2019-09-23 |
2021-04-01 |
Massachusetts Institute Of Technology |
Methods and compositions for stimulation of endogenous t cell responses
|
|
AU2020361683A1
(en)
*
|
2019-10-11 |
2022-05-19 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for targeting CD13 and TIM-3 with CAR T cells to treat acute myeloid leukemia
|
|
EP4045663A2
(en)
*
|
2019-10-16 |
2022-08-24 |
Umoja Biopharma, Inc. |
Retroviral vector for univeral receptor therapy
|
|
IL292665B2
(en)
|
2019-11-06 |
2026-02-01 |
Kite Pharma Inc |
Chimeric antigen receptor T cell therapy
|
|
JP7805928B2
(ja)
|
2019-11-26 |
2026-01-26 |
ノバルティス アーゲー |
Cd19及びcd22キメラ抗原受容体及びその使用
|
|
WO2021108661A2
(en)
|
2019-11-26 |
2021-06-03 |
Novartis Ag |
Chimeric antigen receptors and uses thereof
|
|
JP2023507432A
(ja)
|
2019-12-20 |
2023-02-22 |
インスティル バイオ (ユーケイ) リミテッド |
腫瘍浸潤リンパ球を単離するためのデバイスおよび方法ならびにそれらの使用
|
|
US12076343B2
(en)
|
2020-02-19 |
2024-09-03 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Engineered safety in cell therapy
|
|
WO2021168375A1
(en)
|
2020-02-20 |
2021-08-26 |
Kite Pharma, Inc. |
Chimeric antigen receptor t cell therapy
|
|
IL296242A
(en)
|
2020-03-10 |
2022-11-01 |
Massachusetts Inst Technology |
Methods for generating engineered memory-like nk cells and compositions thereof
|
|
US11896619B2
(en)
|
2020-03-10 |
2024-02-13 |
Massachusetts Institute Of Technology |
Compositions and methods for immunotherapy of NPM1c-positive cancer
|
|
GB202005599D0
(en)
|
2020-04-17 |
2020-06-03 |
Univ London |
Modulation of t cell cytotoxicity and related therapy
|
|
GB202006254D0
(en)
|
2020-04-28 |
2020-06-10 |
Institute Of Cancer Res |
Anti-cancer vaccines and related therapy
|
|
US12433954B2
(en)
|
2020-05-01 |
2025-10-07 |
Massachusetts Institute Of Technology |
Methods of activating anti-CD19 chimeric antigen receptor (CAR) T cells using amphiphilic ligand conjugates comprising CAR-targeting protein sequence motifs
|
|
US20210340524A1
(en)
|
2020-05-01 |
2021-11-04 |
Massachusetts Institute Of Technology |
Methods for identifying chimeric antigen receptor-targeting ligands and uses thereof
|
|
US12202882B2
(en)
|
2020-05-08 |
2025-01-21 |
Alpine Immune Sciences, Inc. |
APRIL and BAFF inhibitory immunomodulatory proteins and methods of use thereof
|
|
US12043654B2
(en)
|
2020-06-02 |
2024-07-23 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Anti-GCC antibody and CAR thereof for treating digestive system cancer
|
|
US20230293530A1
(en)
|
2020-06-24 |
2023-09-21 |
Yeda Research And Development Co. Ltd. |
Agents for sensitizing solid tumors to treatment
|
|
CN116348485A
(zh)
|
2020-07-17 |
2023-06-27 |
英研生物(英国)有限公司 |
提供用于过继性细胞疗法的靶向共刺激的受体
|
|
KR20230084470A
(ko)
|
2020-08-14 |
2023-06-13 |
카이트 파마 인코포레이티드 |
면역 세포 기능의 향상
|
|
WO2022040163A1
(en)
*
|
2020-08-18 |
2022-02-24 |
Delfi Diagnostics, Inc. |
Methods and systems for cell-free dna fragment size densities to assess cancer
|
|
EP4501951A3
(en)
|
2020-08-25 |
2025-04-30 |
Kite Pharma, Inc. |
T cells with improved functionality
|
|
AU2021347320A1
(en)
|
2020-09-24 |
2023-05-11 |
The Jackson Laboratory |
Humanized mouse models for assessing immune cell therapy
|
|
TW202241935A
(zh)
|
2020-12-18 |
2022-11-01 |
美商世紀治療股份有限公司 |
具有可調適受體專一性之嵌合抗原受體系統
|
|
WO2022140159A1
(en)
|
2020-12-24 |
2022-06-30 |
Kite Pharma, Inc. |
Prostate cancer chimeric antigen receptors
|
|
WO2022150582A1
(en)
|
2021-01-10 |
2022-07-14 |
Kite Pharma, Inc. |
T cell therapy
|
|
JP2024507199A
(ja)
|
2021-02-20 |
2024-02-16 |
カイト ファーマ インコーポレイテッド |
免疫療法を選択するための遺伝子マーカー
|
|
KR20230155521A
(ko)
|
2021-03-11 |
2023-11-10 |
카이트 파마 인코포레이티드 |
면역 세포 기능의 향상
|
|
CN112794911B
(zh)
*
|
2021-04-14 |
2021-08-03 |
上海偌妥生物科技有限公司 |
人源化抗叶酸受体1抗体及其应用
|
|
US12337035B2
(en)
|
2021-04-16 |
2025-06-24 |
Kite Pharma, Inc. |
TACI binding molecules
|
|
CN117203328A
(zh)
|
2021-04-27 |
2023-12-08 |
武田药品工业株式会社 |
重组抗原呈递细胞
|
|
KR20230173179A
(ko)
|
2021-05-14 |
2023-12-26 |
카이트 파마 인코포레이티드 |
키메라 항원 수용체 t세포 요법
|
|
AU2022282266B2
(en)
|
2021-05-24 |
2025-09-18 |
Kite Pharma, Inc. |
NKG2D-based chimeric antigen receptor
|
|
US20240277842A1
(en)
|
2021-06-07 |
2024-08-22 |
Providence Health & Services - Oregon |
Cxcr5, pd-1, and icos expressing tumor reactive cd4 t cells and their use
|
|
WO2022261061A1
(en)
|
2021-06-08 |
2022-12-15 |
Kite Pharma, Inc. |
Gpc3 binding molecules
|
|
TW202306997A
(zh)
|
2021-06-16 |
2023-02-16 |
英商英斯特生物科技有限公司 |
用於在過繼細胞療法中提供標靶共刺激之受體
|
|
CN115491360A
(zh)
*
|
2021-06-18 |
2022-12-20 |
复星凯特生物科技有限公司 |
一种靶向nkg2d配体和folr1双打靶点car t的制备及应用
|
|
CN115572715A
(zh)
*
|
2021-06-21 |
2023-01-06 |
复星凯特生物科技有限公司 |
一种靶向folr1和her2双打靶点car t的制备及应用
|
|
WO2023278553A1
(en)
|
2021-07-01 |
2023-01-05 |
Kite Pharma, Inc. |
Closed-system and method for autologous and allogeneic cell therapy manufacturing
|
|
US20230103457A1
(en)
|
2021-07-02 |
2023-04-06 |
Kite Pharma, Inc. |
Method for identifying variants in gene products from gene constructs used in cell therapy applications
|
|
EP4370213A4
(en)
|
2021-07-16 |
2025-06-04 |
Instil Bio (Uk) Limited |
Chimeric molecules for targeted costimulation for adoptive cell therapy
|
|
US11615874B1
(en)
|
2021-09-30 |
2023-03-28 |
Vineti Inc. |
Personalized medicine and therapies platform
|
|
US20260083848A1
(en)
|
2021-11-03 |
2026-03-26 |
Viracta Therapeutics, Inc. |
Combination of car t-cell therapy with btk inhibitors and methods of use thereof
|
|
JP2025503546A
(ja)
|
2021-12-30 |
2025-02-04 |
ティーアール1エックス,インコーポレーテッド |
Il-10およびキメラ抗原受容体を発現するcd4+t細胞およびその使用
|
|
EP4463549A2
(en)
|
2022-01-14 |
2024-11-20 |
Tune Therapeutics, Inc. |
Compositions, systems, and methods for programming t cell phenotypes through targeted gene repression
|
|
US20250134999A1
(en)
|
2022-01-14 |
2025-05-01 |
Tune Therapeutics, Inc. |
Compositions, systems, and methods for programming t cell phenotypes through targeted gene activation
|
|
CN118742810A
(zh)
|
2022-02-15 |
2024-10-01 |
凯德药业股份有限公司 |
从免疫疗法预测不良事件
|
|
US20250243260A1
(en)
|
2022-03-07 |
2025-07-31 |
Alpine Immune Sciences, Inc. |
Immunomodulatory proteins of variant cd80 polypeptides, cell therapies and related methods and uses
|
|
CA3253035A1
(en)
|
2022-06-09 |
2023-12-14 |
Kite Pharma, Inc. |
METHODS FOR PREPARING LYMPHOCYTES FOR CELL THERAPY
|
|
CN119816590A
(zh)
|
2022-08-10 |
2025-04-11 |
武田药品工业株式会社 |
低免疫原性的经修饰细胞
|
|
JP2025531268A
(ja)
|
2022-09-19 |
2025-09-19 |
チューン セラピューティクス インコーポレイテッド |
T細胞機能を調節するための組成物、システム、および方法
|
|
TWI882495B
(zh)
|
2022-10-28 |
2025-05-01 |
美商凱特製藥公司 |
用於將免疫療法最佳化之因素
|
|
JP2026508791A
(ja)
|
2022-10-28 |
2026-03-13 |
カイト ファーマ インコーポレイテッド |
免疫療法の有効性及び永続的奏効の改善
|
|
CN120917153A
(zh)
|
2023-03-17 |
2025-11-07 |
凯德药业股份有限公司 |
肿瘤微环境对免疫疗法疗效的影响
|
|
WO2024206549A2
(en)
*
|
2023-03-29 |
2024-10-03 |
Cellicure, Inc. |
Engineered immune cells and use thereof
|
|
JP2026518850A
(ja)
|
2023-04-27 |
2026-06-10 |
武田薬品工業株式会社 |
Cd56+/cd3-細胞の増殖方法
|
|
EP4754248A1
(en)
|
2023-07-31 |
2026-06-10 |
Tune Therapeutics, Inc. |
Compositions and methods for multiplexed activation and repression of t cell gene expression
|
|
CN121909284A
(zh)
|
2023-07-31 |
2026-04-21 |
图恩疗法股份有限公司 |
用于调节il-2基因表达的组合物和方法
|
|
US20250161361A1
(en)
|
2023-11-01 |
2025-05-22 |
Kite Pharma, Inc. |
Factors for optimizing immunotherapy efficacy
|
|
US20250290154A1
(en)
|
2024-03-04 |
2025-09-18 |
Kite Pharma, Inc. |
Predictive markers for immunotherapy
|
|
WO2026015450A1
(en)
|
2024-07-06 |
2026-01-15 |
Tr1X, Inc. |
Cd4+ t cells expressing il-10 and chimeric antigen receptors and uses thereof
|
|
WO2026069206A1
(en)
|
2024-09-25 |
2026-04-02 |
Takeda Pharmaceutical Company Limited |
Hypoimmunogenic modified gamma delta t cells
|
|
WO2026082736A1
(en)
|
2024-10-14 |
2026-04-23 |
Cimeio Therapeutics Ag |
Chimeric antigen receptor (car) that targets receptor-type tyrosine phosphatase c (cd45) and its use to related applications
|
|
US20260224626A1
(en)
|
2024-11-04 |
2026-08-06 |
Kite Pharma, Inc. |
Biomarkers related to immunotherapy efficacy
|