|
US2802005A
(en)
|
|
1957-08-06 |
|
S-eluorourace |
|
US729332A
(en)
*
|
1902-07-21 |
1903-05-26 |
Frank C Guss |
Animal catching and holding device.
|
|
US2885396A
(en)
|
1957-03-21 |
1959-05-05 |
Heidelberger Charles |
N-glycosides of 5-fluorouracil
|
|
US3773919A
(en)
|
1969-10-23 |
1973-11-20 |
Du Pont |
Polylactide-drug mixtures
|
|
US3885035A
(en)
|
1972-04-05 |
1975-05-20 |
Sandoz Ag |
Method for treating arrhythmia by using 1,4-bis(4 quinazolinyl) piperazines
|
|
CH605550A5
(https=)
|
1972-06-08 |
1978-09-29 |
Research Corp |
|
|
US3956495A
(en)
|
1973-10-30 |
1976-05-11 |
Eli Lilly And Company |
2,4-Diaminoquinazolines as antithrombotic agents
|
|
US3966936A
(en)
|
1974-02-21 |
1976-06-29 |
Pfizer Inc. |
Piperazino quinazoline bronchodilators
|
|
US4060615A
(en)
|
1976-02-18 |
1977-11-29 |
Mead Johnson & Company |
2-Piperazinyl-6,7-dimethoxyquinazolines
|
|
JPS6041077B2
(ja)
|
1976-09-06 |
1985-09-13 |
喜徳 喜谷 |
1,2‐ジアミノシクロヘキサン異性体のシス白金(2)錯体
|
|
JPS562968A
(en)
|
1979-06-21 |
1981-01-13 |
Mitsubishi Yuka Yakuhin Kk |
Novel pyrimidine derivative
|
|
US5260291A
(en)
|
1981-08-24 |
1993-11-09 |
Cancer Research Campaign Technology Limited |
Tetrazine derivatives
|
|
US4526988A
(en)
|
1983-03-10 |
1985-07-02 |
Eli Lilly And Company |
Difluoro antivirals and intermediate therefor
|
|
ATE92499T1
(de)
|
1984-12-04 |
1993-08-15 |
Lilly Co Eli |
Tumorbehandlung bei saeugetieren.
|
|
US4749704A
(en)
|
1985-03-07 |
1988-06-07 |
Sankyo Company Limited |
Cyclopenta[d]pyrimidine derivatives and use as antidepressants
|
|
US5583024A
(en)
|
1985-12-02 |
1996-12-10 |
The Regents Of The University Of California |
Recombinant expression of Coleoptera luciferase
|
|
EP0257102B1
(en)
|
1986-02-24 |
1997-11-19 |
Mitsui Petrochemical Industries, Ltd. |
Agents for treating neurophathy
|
|
FR2601675B1
(fr)
|
1986-07-17 |
1988-09-23 |
Rhone Poulenc Sante |
Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
|
|
US4889856A
(en)
|
1987-08-31 |
1989-12-26 |
Merck & Co., Inc. |
7,8-dihydro-4-(1-pierazinyl)-6H-thiopyrano-[3,2-d] pyrimidines as β-blockers
|
|
US4871739A
(en)
|
1987-01-21 |
1989-10-03 |
Merck & Co., Inc. |
Substituted 6H-7,8-dihydrothiapyrano(3,2-D)-pyrimidines as hyopglycemic agents
|
|
US4994464A
(en)
|
1987-08-31 |
1991-02-19 |
Merck & Co., Inc. |
Piperazinylpyrimidines as β-adrenergic receptor blockers
|
|
MX19185A
(es)
|
1989-01-20 |
1993-12-01 |
Pfizer |
Procedimiento para preparar 3-(1,2,5,6-tretrahidropiridil)-pirrolopiridinas.
|
|
US6582959B2
(en)
|
1991-03-29 |
2003-06-24 |
Genentech, Inc. |
Antibodies to vascular endothelial cell growth factor
|
|
US20030206899A1
(en)
|
1991-03-29 |
2003-11-06 |
Genentech, Inc. |
Vascular endothelial cell growth factor antagonists
|
|
WO1994004679A1
(en)
|
1991-06-14 |
1994-03-03 |
Genentech, Inc. |
Method for making humanized antibodies
|
|
EP1400536A1
(en)
|
1991-06-14 |
2004-03-24 |
Genentech Inc. |
Method for making humanized antibodies
|
|
US5698582A
(en)
|
1991-07-08 |
1997-12-16 |
Rhone-Poulenc Rorer S.A. |
Compositions containing taxane derivatives
|
|
US5750561A
(en)
|
1991-07-08 |
1998-05-12 |
Rhone-Poulenc Rorer, S.A. |
Compositions containing taxane derivatives
|
|
US5714512A
(en)
|
1991-07-08 |
1998-02-03 |
Rhone-Poulenc Rorer, S.A. |
Compositions containing taxane derivatives
|
|
US5604213A
(en)
|
1992-03-31 |
1997-02-18 |
British Technology Group Limited |
17-substituted steroids useful in cancer treatment
|
|
WO1994007890A1
(fr)
|
1992-10-05 |
1994-04-14 |
Ube Industries, Ltd. |
Compose pyrimidine
|
|
BR9207175A
(pt)
|
1992-10-28 |
1995-12-12 |
Genentech Inc |
Composição contendo antagonista de fator de crescimento de célula endotelial vascular sequência aminoácida de anticorpo monoclonal polipeptídeo e método de tratamento de tumor em mamífero
|
|
FR2698543B1
(fr)
|
1992-12-02 |
1994-12-30 |
Rhone Poulenc Rorer Sa |
Nouvelles compositions à base de taxoides.
|
|
WO1995003286A1
(en)
|
1993-07-23 |
1995-02-02 |
The Green Cross Corporation |
Triazole derivative and pharmaceutical use thereof
|
|
US5595756A
(en)
|
1993-12-22 |
1997-01-21 |
Inex Pharmaceuticals Corporation |
Liposomal compositions for enhanced retention of bioactive agents
|
|
GB9416189D0
(en)
|
1994-08-10 |
1994-09-28 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
JP2896532B2
(ja)
|
1994-08-13 |
1999-05-31 |
ユーハン コーポレーション |
新規なピリミジン誘導体およびその製造方法
|
|
US5543523A
(en)
|
1994-11-15 |
1996-08-06 |
Regents Of The University Of Minnesota |
Method and intermediates for the synthesis of korupensamines
|
|
US5525625A
(en)
|
1995-01-24 |
1996-06-11 |
Warner-Lambert Company |
2-(2-Amino-3-methoxyphenyl)-4-oxo-4H-[1]benzopyran for treating proliferative disorders
|
|
IL117645A
(en)
|
1995-03-30 |
2005-08-31 |
Genentech Inc |
Vascular endothelial cell growth factor antagonists for use as medicaments in the treatment of age-related macular degeneration
|
|
JPH08336393A
(ja)
|
1995-04-13 |
1996-12-24 |
Mitsubishi Chem Corp |
光学活性なγ−置換−β−ヒドロキシ酪酸エステルの製造法
|
|
US7125880B1
(en)
|
1995-06-06 |
2006-10-24 |
Pfizer Inc. |
Corticotropin releasing factor antagonists
|
|
US5747498A
(en)
|
1996-05-28 |
1998-05-05 |
Pfizer Inc. |
Alkynyl and azido-substituted 4-anilinoquinazolines
|
|
US7294332B2
(en)
|
1995-10-04 |
2007-11-13 |
Schering Corporation |
Combination therapy (temozolomide and α-IFN) for advanced cancer
|
|
ZA979961B
(en)
|
1996-11-15 |
1999-05-05 |
Lilly Co Eli |
5-HT1F agonists
|
|
UA73073C2
(uk)
|
1997-04-03 |
2005-06-15 |
Уайт Холдінгз Корпорейшн |
Заміщені 3-ціанохіноліни, спосіб їх одержання та фармацевтична композиція
|
|
US20020032315A1
(en)
|
1997-08-06 |
2002-03-14 |
Manuel Baca |
Anti-vegf antibodies
|
|
EP2338915A3
(en)
|
1997-04-07 |
2011-10-12 |
Genentech, Inc. |
Anti-VEGF antibodies
|
|
JP3957765B2
(ja)
|
1997-04-07 |
2007-08-15 |
ジェネンテク・インコーポレイテッド |
抗vegf抗体
|
|
US6884879B1
(en)
|
1997-04-07 |
2005-04-26 |
Genentech, Inc. |
Anti-VEGF antibodies
|
|
CA2290509A1
(en)
|
1997-07-01 |
1999-01-14 |
Warner-Lambert Company |
2-(4-bromo or 4-iodo phenylamino) benzoic acid derivatives and their use as mek inhibitors
|
|
US6821963B2
(en)
|
1997-07-01 |
2004-11-23 |
Warner-Lambert Company |
4-Bromo or 4-iodo phenylamino benzhydroxamic acid derivatives and their use as MEK inhibitors
|
|
US6310060B1
(en)
|
1998-06-24 |
2001-10-30 |
Warner-Lambert Company |
2-(4-bromo or 4-iodo phenylamino) benzoic acid derivatives and their use as MEK inhibitors
|
|
US6506798B1
(en)
|
1997-07-01 |
2003-01-14 |
Warner-Lambert Company |
4-Arylamino, 4-aryloxy, and 4-arylthio diarylamines and derivatives thereof as selective MEK inhibitors
|
|
NZ501276A
(en)
|
1997-07-01 |
2000-10-27 |
Warner Lambert Co |
4-bromo or 4-iodo phenylamino benzhydroxamic acid derivatives and their use as MEK inhibitors in treating proliferative disorders
|
|
US6602677B1
(en)
|
1997-09-19 |
2003-08-05 |
Promega Corporation |
Thermostable luciferases and methods of production
|
|
RS49779B
(sr)
|
1998-01-12 |
2008-06-05 |
Glaxo Group Limited, |
Biciklična heteroaromatična jedinjenja kao inhibitori protein tirozin kinaze
|
|
DE69943144D1
(de)
|
1998-03-31 |
2011-03-03 |
Kyowa Hakko Kirin Co Ltd |
Stickstoffenthaltende heterocyclische verbindungen
|
|
DE19853278A1
(de)
|
1998-11-19 |
2000-05-25 |
Aventis Pharma Gmbh |
Substituierte 4-Amino-2-aryl-cyclopenta[d]pyrimidine, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
|
|
JP2002534380A
(ja)
|
1999-01-07 |
2002-10-15 |
ワーナー−ランバート・カンパニー |
Mek阻害剤による喘息の治療
|
|
AU2203800A
(en)
|
1999-01-07 |
2000-07-24 |
Warner-Lambert Company |
Antiviral method using mek inhibitors
|
|
CA2348236A1
(en)
|
1999-01-13 |
2000-07-20 |
Stephen Douglas Barrett |
4-arylamino, 4-aryloxy, and 4-arylthio diarylamines and derivatives thereof as selective mek inhibitors
|
|
EP1144372B1
(en)
|
1999-01-13 |
2005-11-30 |
Warner-Lambert Company Llc |
Sulphohydroxamic acids and sulphohydroxamates and their use as mek inhibitors
|
|
EP1150950A2
(en)
|
1999-01-13 |
2001-11-07 |
Warner-Lambert Company |
Anthranilic acid derivatives
|
|
CA2355470C
(en)
|
1999-01-13 |
2008-09-30 |
Warner-Lambert Company |
Benzoheterocycles and their use as mek inhibitors
|
|
CA2349832A1
(en)
|
1999-01-13 |
2000-07-20 |
Warner-Lambert Company |
Benzenesulfonamide derivatives and their use as mek inhibitors
|
|
HUP0105092A3
(en)
|
1999-01-13 |
2003-12-29 |
Warner Lambert Co |
1-heterocycle substituted diarylamines and medicaments containing them
|
|
US9534254B1
(en)
|
1999-02-02 |
2017-01-03 |
Abbott Molecular Inc. |
Patient stratification for cancer therapy based on genomic DNA microarray analysis
|
|
US6703020B1
(en)
|
1999-04-28 |
2004-03-09 |
Board Of Regents, The University Of Texas System |
Antibody conjugate methods for selectively inhibiting VEGF
|
|
GB9910577D0
(en)
|
1999-05-08 |
1999-07-07 |
Zeneca Ltd |
Chemical compounds
|
|
US6949245B1
(en)
|
1999-06-25 |
2005-09-27 |
Genentech, Inc. |
Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies
|
|
ATE377597T1
(de)
|
1999-07-09 |
2007-11-15 |
Glaxo Group Ltd |
Anilinochinazoline als protein-tyrosin- kinasehemmer
|
|
US6933299B1
(en)
|
1999-07-09 |
2005-08-23 |
Smithkline Beecham Corporation |
Anilinoquinazolines as protein tyrosine kinase inhibitors
|
|
CA2377092A1
(en)
|
1999-07-16 |
2001-01-25 |
Warner-Lambert Company |
Method for treating chronic pain using mek inhibitors
|
|
JP2003504401A
(ja)
|
1999-07-16 |
2003-02-04 |
ワーナー−ランバート・カンパニー |
Mek阻害剤を用いる慢性疼痛の治療方法
|
|
JP2003504400A
(ja)
|
1999-07-16 |
2003-02-04 |
ワーナー−ランバート・カンパニー |
Mek阻害剤を用いた慢性痛の治療方法
|
|
EP1202732A2
(en)
|
1999-07-16 |
2002-05-08 |
Warner-Lambert Company Llc |
Method for treating chronic pain using mek inhibitors
|
|
UA74803C2
(uk)
|
1999-11-11 |
2006-02-15 |
Осі Фармасьютікалз, Інк. |
Стійкий поліморф гідрохлориду n-(3-етинілфеніл)-6,7-біс(2-метоксіетокси)-4-хіназолінаміну, спосіб його одержання (варіанти) та фармацевтичне застосування
|
|
BR0109188A
(pt)
|
2000-03-15 |
2003-03-18 |
Warner Lambert Co |
Diarilaminas 5-amida substituìdas como inibidores de mex
|
|
PL204958B1
(pl)
|
2000-06-30 |
2010-02-26 |
Glaxo Group Ltd |
Ditosylany związków chinazolinowych, środek farmaceutyczny i zastosowanie tych związków
|
|
DZ3401A1
(fr)
|
2000-07-19 |
2002-01-24 |
Warner Lambert Co |
Esters oxygenes d'acides 4-iodophenylamino benzhydroxamiques
|
|
KR20030059115A
(ko)
|
2000-08-25 |
2003-07-07 |
워너-램버트 캄파니 엘엘씨 |
N-아릴-안트라닐산 및 그의 유도체의 제조 방법
|
|
EP1317450B1
(en)
|
2000-09-15 |
2006-11-22 |
Vertex Pharmaceuticals Incorporated |
Pyrazole compounds useful as protein kinase inhibitors
|
|
EP1337524A1
(en)
|
2000-11-02 |
2003-08-27 |
AstraZeneca AB |
Substituted quinolines as antitumor agents
|
|
DE60203260T2
(de)
|
2001-01-16 |
2006-02-02 |
Glaxo Group Ltd., Greenford |
Pharmazeutische kombination, die ein 4-chinazolinamin und paclitaxel, carboplatin oder vinorelbin enthält, zur behandlung von krebs
|
|
WO2002083139A1
(en)
|
2001-04-10 |
2002-10-24 |
Merck & Co., Inc. |
Inhibitors of akt activity
|
|
IL158062A0
(en)
|
2001-04-30 |
2004-03-28 |
Glaxo Group Ltd |
Fused pyrimidines as antagonists of the corticotropin releasing factor (crf)
|
|
IL149462A0
(en)
|
2001-05-09 |
2002-11-10 |
Warner Lambert Co |
Method of treating or inhibiting neutrophil chemotaxis by administering a mek inhibitor
|
|
AU2002336462A1
(en)
|
2001-09-06 |
2003-03-24 |
Millennium Pharmaceuticals, Inc. |
Piperazine and homopiperazine compounds
|
|
US20050107404A1
(en)
|
2001-12-06 |
2005-05-19 |
Fraley Mark E. |
Mitotic kinesin inhibitors
|
|
US20030187026A1
(en)
|
2001-12-13 |
2003-10-02 |
Qun Li |
Kinase inhibitors
|
|
JP4469179B2
(ja)
|
2002-01-23 |
2010-05-26 |
バイエル ファーマセチカル コーポレーション |
Rhoキナーゼ阻害剤としてのピリミジン誘導体
|
|
TW200306819A
(en)
|
2002-01-25 |
2003-12-01 |
Vertex Pharma |
Indazole compounds useful as protein kinase inhibitors
|
|
SG2013013339A
(en)
|
2002-03-13 |
2014-12-30 |
Array Biopharma Inc |
N3 alkylated benzimidazole derivatives as mek inhibitors
|
|
EP1482944A4
(en)
|
2002-03-13 |
2006-04-19 |
Array Biopharma Inc |
NZ ALKYL BENZIMIDAZOLE DERIVATIVES AS MEK INHIBITORS
|
|
US7235537B2
(en)
|
2002-03-13 |
2007-06-26 |
Array Biopharma, Inc. |
N3 alkylated benzimidazole derivatives as MEK inhibitors
|
|
US7223738B2
(en)
|
2002-04-08 |
2007-05-29 |
Merck & Co., Inc. |
Inhibitors of Akt activity
|
|
EP1494675A4
(en)
|
2002-04-08 |
2006-07-19 |
Merck & Co Inc |
HEMMER OF ACT ACTIVITY
|
|
CA2481241C
(en)
|
2002-04-08 |
2010-07-27 |
Merck & Co., Inc. |
Fused quinoxaline derivatives as inhibitors of akt activity
|
|
CA2480880C
(en)
|
2002-04-08 |
2011-03-22 |
Merck & Co., Inc. |
Inhibitors of akt activity
|
|
JP2005534632A
(ja)
|
2002-05-10 |
2005-11-17 |
ニューロクライン バイオサイエンセズ, インコーポレイテッド |
メラノコルチンレセプターリガンドとしての置換ピペラジン
|
|
US20040102360A1
(en)
|
2002-10-30 |
2004-05-27 |
Barnett Stanley F. |
Combination therapy
|
|
JP2006507299A
(ja)
|
2002-10-30 |
2006-03-02 |
メルク エンド カムパニー インコーポレーテッド |
Akt活性の阻害薬
|
|
JP2006508974A
(ja)
|
2002-11-15 |
2006-03-16 |
ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー |
癌を治療するためのmek阻害剤およびカペシタビン(capecitabine)を含む併用化学療法
|
|
BR0316680A
(pt)
|
2002-11-28 |
2005-10-18 |
Schering Ag |
Pirimidinas inibidoras de chk, pdk e akt, sua produção e uso como agentes farmacêuticos
|
|
GB0308208D0
(en)
|
2003-04-09 |
2003-05-14 |
Glaxo Group Ltd |
Chemical compounds
|
|
EP1620095A4
(en)
|
2003-04-24 |
2009-04-01 |
Merck & Co Inc |
HEMMER OF ACT ACTIVITY
|
|
MXPA05012723A
(es)
|
2003-05-30 |
2006-02-08 |
Genentech Inc |
Tratamiento con anticuerpos anti-vgf.
|
|
DE602004022819D1
(de)
|
2003-06-06 |
2009-10-08 |
Vertex Pharma |
Von atp-bindende kassette transportern
|
|
AR045134A1
(es)
|
2003-07-29 |
2005-10-19 |
Smithkline Beecham Plc |
Compuesto de 1h - imidazo [4,5-c] piridin-ilo, composicion farmaceutica que lo comprende, proceso para prepararla, su uso para preparar dicha composicion farmaceutica, combinacion farmaceutica, uso de la combinacion farmaceutica para la preparacion de un medicamento, procedimientos para preparar dic
|
|
WO2005044853A2
(en)
|
2003-11-01 |
2005-05-19 |
Genentech, Inc. |
Anti-vegf antibodies
|
|
US20050106667A1
(en)
|
2003-08-01 |
2005-05-19 |
Genentech, Inc |
Binding polypeptides with restricted diversity sequences
|
|
ZA200601859B
(en)
|
2003-08-05 |
2008-03-26 |
Vertex Pharma |
Condensed pyrimidine compounds as inhibitors of voltagegated ion channels
|
|
JP2007501821A
(ja)
|
2003-08-12 |
2007-02-01 |
エフ.ホフマン−ラ ロシュ アーゲー |
Cfrアンタゴニストとしてのテトラヒドロキナゾリン誘導体
|
|
MXPA06002618A
(es)
|
2003-09-09 |
2006-06-05 |
Ono Pharmaceutical Co |
Antagonistas del factor de liberacion de corticotropina (crf) y compuestos heterobiciclicos.
|
|
US20050182061A1
(en)
|
2003-10-02 |
2005-08-18 |
Jeremy Green |
Phthalimide compounds useful as protein kinase inhibitors
|
|
WO2005040098A1
(en)
|
2003-10-21 |
2005-05-06 |
Warner-Lambert Company Llc |
Polymorphic form of n-[(r)-2,3-dihydroxy-propoxy]-3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-benzamide
|
|
CA2546754A1
(en)
|
2003-11-21 |
2005-06-09 |
Array Biopharma Inc. |
Akt protein kinase inhibitors
|
|
CA2550361C
(en)
|
2003-12-19 |
2014-04-29 |
Prabha Ibrahim |
Compounds and methods for development of ret modulators
|
|
AU2005228410A1
(en)
|
2004-03-29 |
2005-10-13 |
University Of South Florida |
Effective treatment of tumors and cancer with triciribine and related compounds
|
|
WO2005117909A2
(en)
|
2004-04-23 |
2005-12-15 |
Exelixis, Inc. |
Kinase modulators and methods of use
|
|
US7531556B2
(en)
|
2004-04-28 |
2009-05-12 |
Vertex Pharmaceuticals Incorporated |
Compositions useful as inhibitors of rock and other protein kinases
|
|
US20060009360A1
(en)
|
2004-06-25 |
2006-01-12 |
Robert Pifer |
New adjuvant composition
|
|
EP1763526B1
(en)
|
2004-06-28 |
2009-06-24 |
Bayer Schering Pharma AG |
4,6-disubstituted pyrimidines and their use as protein kinase inhibitors
|
|
US20060025074A1
(en)
|
2004-07-30 |
2006-02-02 |
Chih-Ming Liang |
Bluetooth-based headset
|
|
TWM266655U
(en)
|
2004-09-23 |
2005-06-01 |
Blueexpert Technology Corp |
Bluetooth earphone device capable of wirelessly receiving and transmitting stereo sound signal and digital information signal
|
|
TW200621257A
(en)
|
2004-10-20 |
2006-07-01 |
Astellas Pharma Inc |
Pyrimidine derivative fused with nonaromatic ring
|
|
UY29177A1
(es)
|
2004-10-25 |
2006-05-31 |
Astex Therapeutics Ltd |
Derivados sustituidos de purina, purinona y deazapurina, composiciones que los contienen métodos para su preparación y sus usos
|
|
CA2590961C
(en)
|
2004-12-28 |
2013-11-26 |
Exelixis, Inc. |
[1h-pyrazolo[3,4-d]pyrimidin-4-yl]-piperidine or -piperazine compounds as serine-threonine kinase modulators (p70s6k, atk1 and atk2) for the treatment of immunological, inflammatory and proliferative diseases
|
|
US20090111805A1
(en)
|
2005-02-24 |
2009-04-30 |
Pfizer Inc. |
Bicyclic heteroaromatic derivatives useful as anticancer agents
|
|
CA2600745A1
(en)
|
2005-03-03 |
2006-09-08 |
The Burnham Institute For Medical Research |
Screening methods for protein kinase b inhibitors employing virtual docking approaches and compounds and compositions discovered thereby
|
|
US7709517B2
(en)
|
2005-05-13 |
2010-05-04 |
The Regents Of The University Of California |
Diarylhydantoin compounds
|
|
WO2006127587A1
(en)
|
2005-05-20 |
2006-11-30 |
Vertex Pharmaceuticals Incorporated |
Pyrrolopyridines useful as inhibitors of protein kinase
|
|
UY29610A1
(es)
|
2005-06-21 |
2007-01-31 |
Cancer Rec Tech Ltd |
Aril-alquilaminas y heteroaril-alquilaminas como inhibidores de la quinasa proteínica
|
|
CN102206216B
(zh)
|
2005-06-22 |
2014-11-12 |
普莱希科公司 |
作为蛋白质激酶抑制剂的吡咯并[2,3-b]吡啶衍生物
|
|
HRP20110498T1
(hr)
|
2005-10-07 |
2011-08-31 |
Exelixis |
Azetidini kao inhibitori mek za liječenje proliferativnih bolesti
|
|
WO2007042298A1
(en)
|
2005-10-13 |
2007-04-19 |
Glaxo Group Limited |
Pyrrolopyrimidine derivatives as syk inhibitors
|
|
US7960545B2
(en)
*
|
2005-11-23 |
2011-06-14 |
Natco Pharma Limited |
Process for the prepartion of erlotinib
|
|
CA2635541A1
(en)
|
2005-12-28 |
2007-07-12 |
Takeda Pharmaceutical Company Limited |
Fused heterocyclic compounds and their use as mineralocorticoid receptor ligands
|
|
US7814803B2
(en)
†
|
2006-03-02 |
2010-10-19 |
Nsk Ltd. |
Torque sensor
|
|
JP2009534454A
(ja)
|
2006-04-25 |
2009-09-24 |
アステックス、セラピューティックス、リミテッド |
医薬化合物
|
|
RU2008152171A
(ru)
|
2006-07-05 |
2010-08-10 |
Интермьюн, Инк. (Us) |
Новые ингибиторы вирусной репликации гепатита с
|
|
UA95641C2
(xx)
*
|
2006-07-06 |
2011-08-25 |
Эррей Биофарма Инк. |
Гідроксильовані піримідильні циклопентани як інгібітори акт протеїнкінази$гидроксилированные пиримидильные циклопентаны как ингибиторы акт протеинкиназы
|
|
GB0613518D0
(en)
|
2006-07-06 |
2006-08-16 |
Phytopharm Plc |
Chemical compounds
|
|
TW200808325A
(en)
|
2006-07-06 |
2008-02-16 |
Astrazeneca Ab |
Novel compounds
|
|
US8063050B2
(en)
*
|
2006-07-06 |
2011-11-22 |
Array Biopharma Inc. |
Hydroxylated and methoxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitors
|
|
US7910747B2
(en)
|
2006-07-06 |
2011-03-22 |
Bristol-Myers Squibb Company |
Phosphonate and phosphinate pyrazolylamide glucokinase activators
|
|
CA2655675A1
(en)
|
2006-07-06 |
2008-01-10 |
Glaxo Group Limited |
Substituted n-phenylmethyl -5-oxo-proline-2-amides as p2x7-receptor antagonists and their methods of use
|
|
ATE532789T1
(de)
|
2006-07-06 |
2011-11-15 |
Array Biopharma Inc |
Dihydrothienopyrimidine als akt-proteinkinase- inhibitoren
|
|
EP2049500B1
(en)
|
2006-07-06 |
2011-09-07 |
Array Biopharma, Inc. |
Cyclopenta [d] pyrimidines as akt protein kinase inhibitors
|
|
WO2008012635A2
(en)
|
2006-07-26 |
2008-01-31 |
Pfizer Products Inc. |
Amine derivatives useful as anticancer agents
|
|
PE20080538A1
(es)
*
|
2006-08-04 |
2008-06-18 |
Takeda Pharmaceutical |
Derivado heterociclico fusionado y su uso
|
|
EP3804730A1
(en)
|
2006-08-25 |
2021-04-14 |
Janssen Oncology, Inc. |
Compositions for treating cancer
|
|
WO2008094321A2
(en)
|
2006-10-04 |
2008-08-07 |
Universtiy Of South Florida |
Akt sensitization of cancer cells
|
|
CN101332301A
(zh)
*
|
2007-06-26 |
2008-12-31 |
南京医科大学 |
一种抗肿瘤组合物及其应用
|
|
EP2173352B1
(en)
|
2007-07-12 |
2016-09-07 |
University of South Florida |
Inhibitors of akt/pkb with anti-tumor activity
|
|
EP2170062A4
(en)
|
2007-07-12 |
2010-12-29 |
Tragara Pharmaceuticals Inc |
METHOD AND COMPOSITIONS FOR THE TREATMENT OF CANCER DISORDERS, TUMORS AND TUMOR-DISORDED DISEASES
|
|
US8137919B2
(en)
|
2008-04-10 |
2012-03-20 |
Montefiore Medical Center |
Method of determining the sensitivity of cancer cells to EGFR inhibitors including cetuximab, panitumumab and erlotinib
|
|
EP2320903B1
(en)
*
|
2008-07-29 |
2017-01-18 |
Nerviano Medical Sciences S.r.l. |
THERAPEUTIC COMBINATION COMPRISING A CDKs INHIBITOR AND AN ANTINEOPLASTIC AGENT
|
|
AR073354A1
(es)
|
2008-07-31 |
2010-11-03 |
Genentech Inc |
Compuestos de pirimidina, composiciones farmaceuticas y su uso en el tratamiento del cancer.
|
|
EP3617330B1
(en)
*
|
2011-04-01 |
2023-12-27 |
Genentech, Inc. |
Biomarkers for predicting sensitivity to cancer treatments
|
|
KR102021157B1
(ko)
|
2011-04-01 |
2019-09-11 |
제넨테크, 인크. |
Akt 억제제 화합물 및 아비라테론의 조합물, 및 사용 방법
|