PT2694072T - Combinação de composto inibidor de akt e abiraterona para utilização em tratamentos terapêuticos - Google Patents

Combinação de composto inibidor de akt e abiraterona para utilização em tratamentos terapêuticos

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Publication number
PT2694072T
PT2694072T PT127647659T PT12764765T PT2694072T PT 2694072 T PT2694072 T PT 2694072T PT 127647659 T PT127647659 T PT 127647659T PT 12764765 T PT12764765 T PT 12764765T PT 2694072 T PT2694072 T PT 2694072T
Authority
PT
Portugal
Prior art keywords
abiraterone
combination
inhibitor compound
therapeutic treatments
akt inhibitor
Prior art date
Application number
PT127647659T
Other languages
English (en)
Portuguese (pt)
Inventor
Nannini Michelle
Sampath Deepak
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46931958&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2694072(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of PT2694072T publication Critical patent/PT2694072T/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
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    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
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    • C07D—HETEROCYCLIC COMPOUNDS
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    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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  • Health & Medical Sciences (AREA)
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  • Pharmacology & Pharmacy (AREA)
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  • Organic Chemistry (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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  • Steroid Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PT127647659T 2011-04-01 2012-03-30 Combinação de composto inibidor de akt e abiraterona para utilização em tratamentos terapêuticos PT2694072T (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161470803P 2011-04-01 2011-04-01
US201161470624P 2011-04-01 2011-04-01

Publications (1)

Publication Number Publication Date
PT2694072T true PT2694072T (pt) 2018-02-26

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PT127647659T PT2694072T (pt) 2011-04-01 2012-03-30 Combinação de composto inibidor de akt e abiraterona para utilização em tratamentos terapêuticos

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Country Link
US (7) US20150064171A1 (https=)
EP (4) EP2694070A4 (https=)
JP (4) JP6239497B2 (https=)
KR (4) KR102021157B1 (https=)
CN (8) CN107233343A (https=)
AU (4) AU2012236144B2 (https=)
BR (4) BR112013025386B1 (https=)
CA (4) CA2844699C (https=)
DK (1) DK2694072T4 (https=)
ES (3) ES2620644T3 (https=)
FI (1) FI2694072T4 (https=)
HK (1) HK1204575A1 (https=)
HR (1) HRP20180223T4 (https=)
HU (1) HUE036513T2 (https=)
IL (4) IL228642A0 (https=)
LT (1) LT2694072T (https=)
ME (1) ME02998B (https=)
MX (4) MX351892B (https=)
MY (1) MY179607A (https=)
PL (2) PL2694072T5 (https=)
PT (1) PT2694072T (https=)
RS (1) RS56759B2 (https=)
RU (4) RU2013148721A (https=)
SG (5) SG194045A1 (https=)
SI (1) SI2694072T2 (https=)
SM (1) SMT201800250T1 (https=)
TR (1) TR201802093T4 (https=)
WO (4) WO2012135753A1 (https=)
ZA (4) ZA201308062B (https=)

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US9447049B2 (en) 2010-03-01 2016-09-20 University Of Tennessee Research Foundation Compounds for treatment of cancer
AU2009330686B2 (en) 2008-06-16 2014-07-03 The Ohio State University Research Foundation Compounds for the treatment of cancer
US11084811B2 (en) 2010-03-01 2021-08-10 Oncternal Therapeutics, Inc. Compounds for treatment of cancer
TWI674262B (zh) 2011-01-10 2019-10-11 美商英菲尼提製藥股份有限公司 製備異喹啉酮之方法及異喹啉酮之固體形式
JP6100700B2 (ja) 2011-01-11 2017-03-22 ノバルティス アーゲー 組合せ
KR102021157B1 (ko) 2011-04-01 2019-09-11 제넨테크, 인크. Ａｋｔ 억제제 화합물 및 아비라테론의 조합물, 및 사용 방법
US9216170B2 (en) 2012-03-19 2015-12-22 Hoffmann-La Roche Inc. Combination therapy for proliferative disorders
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