PL2694485T3 - Kombinacja związku inhibitora akt i wemurafenibu do zastosowania w leczeniach terapeutycznych - Google Patents

Kombinacja związku inhibitora akt i wemurafenibu do zastosowania w leczeniach terapeutycznych

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Publication number
PL2694485T3
PL2694485T3 PL12765234T PL12765234T PL2694485T3 PL 2694485 T3 PL2694485 T3 PL 2694485T3 PL 12765234 T PL12765234 T PL 12765234T PL 12765234 T PL12765234 T PL 12765234T PL 2694485 T3 PL2694485 T3 PL 2694485T3
Authority
PL
Poland
Prior art keywords
vemurafenib
combination
inhibitor compound
therapeutic treatments
akt inhibitor
Prior art date
Application number
PL12765234T
Other languages
English (en)
Inventor
Klaus Hoeflich
Mark Merchant
Original Assignee
Genentech, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46931958&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2694485(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech, Inc. filed Critical Genentech, Inc.
Publication of PL2694485T3 publication Critical patent/PL2694485T3/pl

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
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  • Health & Medical Sciences (AREA)
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  • Life Sciences & Earth Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
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  • Organic Chemistry (AREA)
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  • Molecular Biology (AREA)
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  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Reproductive Health (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PL12765234T 2011-04-01 2012-03-30 Kombinacja związku inhibitora akt i wemurafenibu do zastosowania w leczeniach terapeutycznych PL2694485T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201161470803P 2011-04-01 2011-04-01
US201161470624P 2011-04-01 2011-04-01
PCT/US2012/031665 WO2012135750A1 (en) 2011-04-01 2012-03-30 Combinations of akt inhibitor compounds and vemurafenib, and methods of use
EP12765234.5A EP2694485B1 (en) 2011-04-01 2012-03-30 Combination of akt inhibitor compound and vemurafenib for use in therapeutic treatments

Publications (1)

Publication Number Publication Date
PL2694485T3 true PL2694485T3 (pl) 2018-04-30

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ID=46931958

Family Applications (2)

Application Number Title Priority Date Filing Date
PL12764765.9T PL2694072T5 (pl) 2011-04-01 2012-03-30 Kombinacja związku inhibitora Akt i abirateronu do zastosowania w leczeniu terapeutycznym
PL12765234T PL2694485T3 (pl) 2011-04-01 2012-03-30 Kombinacja związku inhibitora akt i wemurafenibu do zastosowania w leczeniach terapeutycznych

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PL12764765.9T PL2694072T5 (pl) 2011-04-01 2012-03-30 Kombinacja związku inhibitora Akt i abirateronu do zastosowania w leczeniu terapeutycznym

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US (7) US9150549B2 (pl)
EP (4) EP2694485B1 (pl)
JP (4) JP6143739B2 (pl)
KR (4) KR101950044B1 (pl)
CN (8) CN111643504A (pl)
AU (4) AU2012236144B2 (pl)
BR (4) BR112013025386B1 (pl)
CA (4) CA2831937A1 (pl)
DK (1) DK2694072T4 (pl)
ES (3) ES2657750T3 (pl)
FI (1) FI2694072T4 (pl)
HK (1) HK1204575A1 (pl)
HR (1) HRP20180223T4 (pl)
HU (1) HUE036513T2 (pl)
IL (4) IL228637B (pl)
LT (1) LT2694072T (pl)
ME (1) ME02998B (pl)
MX (4) MX2013011329A (pl)
MY (1) MY179607A (pl)
PL (2) PL2694072T5 (pl)
PT (1) PT2694072T (pl)
RS (1) RS56759B2 (pl)
RU (4) RU2013148728A (pl)
SG (5) SG10201504303SA (pl)
SI (1) SI2694072T2 (pl)
SM (1) SMT201800250T1 (pl)
TR (1) TR201802093T4 (pl)
WO (4) WO2012135759A1 (pl)
ZA (4) ZA201308064B (pl)

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US8193182B2 (en) 2008-01-04 2012-06-05 Intellikine, Inc. Substituted isoquinolin-1(2H)-ones, and methods of use thereof
LT2303021T (lt) 2008-06-16 2019-06-25 University Of Tennessee Research Foundation Junginiai, skirti vėžio gydymui
US9447049B2 (en) 2010-03-01 2016-09-20 University Of Tennessee Research Foundation Compounds for treatment of cancer
US11084811B2 (en) 2010-03-01 2021-08-10 Oncternal Therapeutics, Inc. Compounds for treatment of cancer
PE20180318A1 (es) 2011-01-10 2018-02-09 Infinity Pharmaceuticals Inc Procedimiento para preparar isoquinolinonas y formas solidas de isoquinolinonas
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