|
NL293572A
(enExample)
|
1962-06-07 |
|
|
|
|
US3843681A
(en)
*
|
1971-06-01 |
1974-10-22 |
American Home Prod |
1-carboxamido pyrano(thiopyrano)(3,4-6)indole derivatives
|
|
DE2226703A1
(de)
*
|
1972-05-25 |
1973-12-13 |
Schering Ag |
Neue tetrahydrocarbazolderivate und verfahren zu ihrer herstellung
|
|
US4057559A
(en)
|
1973-10-01 |
1977-11-08 |
American Home Products Corporation |
Carbazole acetic acid derivatives
|
|
US4810699A
(en)
|
1987-02-20 |
1989-03-07 |
American Home Products Corporation |
Substituted 1,3,4,9-tetrahydropyrano[3,4,-b]indole-1-acetic acids, pharmaceutical compositions containing them, and methods for treating inflammatory conditions and for analgesic purposes using them
|
|
US4782076A
(en)
|
1988-03-01 |
1988-11-01 |
American Home Products Corporation |
Substituted 2,3,4,9-tetrahydro-1H-carbazole-1-acetic acid derivatives, composition and use
|
|
PT95692A
(pt)
*
|
1989-10-27 |
1991-09-13 |
American Home Prod |
Processo para a preparacao de derivados de acidos indole-,indeno-,piranoindole- e tetra-hidrocarbazole-alcanoicos, ou quais sao uteis como inibidores de pla2 e da lipoxigenase
|
|
US5221678A
(en)
|
1990-07-26 |
1993-06-22 |
Merck Frosst Canada, Inc. |
(quinolin-2-ylmethoxy)tetrahydrocarbazoles as inhibitors of the biosynthesis of leukotrienes
|
|
US5998499A
(en)
|
1994-03-25 |
1999-12-07 |
Dentsply G.M.B.H. |
Liquid crystalline (meth)acrylate compounds, composition and method
|
|
US5776967A
(en)
|
1996-07-26 |
1998-07-07 |
American Home Products Corporation |
Pyranoindole inhibitors of COX--2
|
|
US5830911A
(en)
|
1996-08-14 |
1998-11-03 |
American Home Products Corporation |
Pyranoindole and tetrahydrocarbazole inhibitors of COX-2
|
|
US6861448B2
(en)
|
1998-01-14 |
2005-03-01 |
Virtual Drug Development, Inc. |
NAD synthetase inhibitors and uses thereof
|
|
JP4038266B2
(ja)
*
|
1998-02-17 |
2008-01-23 |
オイレス工業株式会社 |
粘性せん断型ダンパー
|
|
EP1177187B1
(en)
|
1999-04-28 |
2007-07-25 |
Sanofi-Aventis Deutschland GmbH |
Di-aryl acid derivatives as ppar receptor ligands
|
|
US6410583B1
(en)
|
2000-07-25 |
2002-06-25 |
Merck Frosst Canada & Co. |
Cyclopentanoindoles, compositions containing such compounds and methods of treatment
|
|
WO2002039987A2
(en)
|
2000-11-14 |
2002-05-23 |
Neurosearch A/S |
Use of malaria parasite anion channel blockers for treating malaria
|
|
US7064217B2
(en)
|
2001-01-30 |
2006-06-20 |
University Of Virginia Patent Foundation |
Agonists and antagonists of sphingosine-1-phosphate receptors
|
|
US7534547B2
(en)
|
2001-03-29 |
2009-05-19 |
Osaka Gas Company Limited |
Optically active compound and photosensitive resin composition
|
|
EP1391199B1
(en)
|
2001-05-10 |
2008-12-10 |
Ono Pharmaceutical Co., Ltd. |
Carboxylic acid derivatives and drugs containing the same as the active ingredient
|
|
CA2461212C
(en)
|
2001-09-27 |
2010-08-17 |
Kyorin Pharmaceutical Co., Ltd. |
Diaryl sulfide derivatives, salts thereof and immunosuppressive agents using the same
|
|
ATE441654T1
(de)
|
2002-01-18 |
2009-09-15 |
Merck & Co Inc |
Edg-rezeptoragonisten
|
|
WO2003059346A1
(en)
|
2002-01-18 |
2003-07-24 |
The Genetics Company Inc. |
Beta-secretase inhibitors
|
|
US20050070506A1
(en)
|
2002-01-18 |
2005-03-31 |
Doherty George A. |
Selective s1p1/edg1 receptor agonists
|
|
EP1482896A4
(en)
|
2002-03-01 |
2005-11-23 |
Merck & Co Inc |
AMINO ALKYL PHOSPHONATES AND RELATED COMPOUNDS AS EDG RECEPTOR AGONISTS
|
|
AU2003217764A1
(en)
|
2002-03-01 |
2003-09-16 |
Merck & Co., Inc. |
Aminoalkylphosphonates and related compounds as edg receptor agonists
|
|
EP1549640A4
(en)
|
2002-06-17 |
2008-08-06 |
Merck & Co Inc |
1 - ((5-ARYL-1,2,4-OXADIAZOL-3-YL) BENZYL) AZETIDINE-3-CARBOXYLATE AND 1 - ((5-ARYL-1,2,4-OXADIAZOL-3-YL) BENZYL) PYRROLIDIN-3-CARBOXYLATE AS EDG RECEPTOR AGONISTS
|
|
EP1541563A4
(en)
|
2002-07-10 |
2007-11-07 |
Ono Pharmaceutical Co |
ANTAGONIST OF CCR4 AND CORRESPONDING MEDICINAL USE
|
|
EP1546110A4
(en)
|
2002-07-30 |
2008-03-26 |
Univ Virginia |
COMPOUNDS WITH EFFECT ON SIGNAL TRANSMISSION BY SPHINGOSINE-1-PHOSPHATE
|
|
AU2003277576A1
(en)
|
2002-11-08 |
2004-06-07 |
Takeda Pharmaceutical Company Limited |
Receptor function controlling agent
|
|
CA2509218C
(en)
|
2002-12-20 |
2010-09-07 |
Merck & Co., Inc. |
1-(amino)indanes and (1,2-dihydro-3-amino)-benzofurans, benzothiophenes and indoles as edg receptor agonists
|
|
EP1594508B1
(en)
|
2003-02-11 |
2012-08-08 |
Irm Llc |
Novel bicyclic compounds and compositions
|
|
EP2172472B1
(en)
|
2003-02-18 |
2012-12-26 |
Kyorin Pharmaceutical Co., Ltd. |
Aminophosphonic acid derivative, salt thereof and modulator of S1P receptor
|
|
US7329680B2
(en)
|
2003-04-30 |
2008-02-12 |
The Institute For Pharmaceutical Discovery, Llc |
Heterocycle substituted carboxylic acids
|
|
ES2383298T3
(es)
|
2003-04-30 |
2012-06-20 |
Novartis Ag |
Derivados del amino-propanol como moduladores del receptor esfingosina-1-fosfato
|
|
WO2004096757A1
(en)
|
2003-04-30 |
2004-11-11 |
Novartis Ag |
Aminopropanol derivatives as sphingosine-1-phosphate receptor modulators
|
|
JP2006528980A
(ja)
|
2003-05-15 |
2006-12-28 |
メルク エンド カムパニー インコーポレーテッド |
Ｓ１ｐ受容体作働薬としての３−（２−アミノ−１−アザシクロ）−５−アリール−１，２，４−オキサジアゾール類
|
|
WO2004104205A2
(en)
|
2003-05-16 |
2004-12-02 |
Merck & Co., Inc. |
Enzymatic preparation of chiral indole esters
|
|
MY150088A
(en)
|
2003-05-19 |
2013-11-29 |
Irm Llc |
Immunosuppressant compounds and compositions
|
|
BRPI0410746A
(pt)
|
2003-05-19 |
2006-06-27 |
Irm Llc |
compostos e composições imunossupressoras
|
|
EP1638551B1
(en)
|
2003-05-19 |
2011-12-21 |
Irm Llc |
Immunosuppressant compounds and compositions
|
|
WO2005000833A1
(en)
|
2003-05-19 |
2005-01-06 |
Irm, Llc |
Immunosuppressant compounds and compositions
|
|
GB0313612D0
(en)
|
2003-06-12 |
2003-07-16 |
Novartis Ag |
Organic compounds
|
|
US20100267778A1
(en)
|
2003-08-04 |
2010-10-21 |
Shinya Kusuda |
Diphenyl ether compound, process for producing the same, and use
|
|
PL1660449T3
(pl)
|
2003-08-28 |
2010-05-31 |
Novartis Ag |
Pochodne aminopropanolu
|
|
US7825109B2
(en)
|
2003-08-29 |
2010-11-02 |
Ono Pharmaceutical Co., Ltd. |
Compound capable of binding S1P receptor and pharmaceutical use thereof
|
|
EP1661889A4
(en)
|
2003-09-05 |
2009-08-05 |
Ono Pharmaceutical Co |
ANTAGONIST OF THE CHEMOKINE RECEPTOR AND ITS USE FOR MEDICAL PURPOSES
|
|
AU2004277947A1
(en)
|
2003-10-01 |
2005-04-14 |
Merck & Co., Inc. |
3,5-aryl, heteroaryl or cycloalkyl substituted-1,2,4-oxadiazoles as S1P receptor agonists
|
|
WO2005041899A2
(en)
|
2003-11-03 |
2005-05-12 |
University Of Virginia Patent Foundation |
Orally available sphingosine 1-phosphate receptor agonists and antagonists
|
|
JPWO2005044780A1
(ja)
|
2003-11-10 |
2007-05-17 |
杏林製薬株式会社 |
アミノカルボン酸誘導体とその付加塩及びｓ１ｐ受容体調節剤
|
|
CN1894225A
(zh)
|
2003-12-17 |
2007-01-10 |
默克公司 |
作为鞘氨醇1－磷酸(内皮分化基因)受体激动剂的(3,4－二取代)丙酸酯
|
|
GB0329498D0
(en)
|
2003-12-19 |
2004-01-28 |
Novartis Ag |
Organic compounds
|
|
US7875745B2
(en)
|
2003-12-19 |
2011-01-25 |
Ono Pharmaceutical Co., Ltd. |
Compounds having lysophosphatidic acid receptor antagonism and uses thereof
|
|
GB0401332D0
(en)
|
2004-01-21 |
2004-02-25 |
Novartis Ag |
Organic compounds
|
|
WO2005079788A1
(ja)
|
2004-02-24 |
2005-09-01 |
Sankyo Company, Limited |
アミノアルコール化合物
|
|
TW200538433A
(en)
|
2004-02-24 |
2005-12-01 |
Irm Llc |
Immunosuppressant compounds and compositiions
|
|
WO2005082841A1
(en)
|
2004-02-24 |
2005-09-09 |
Irm Llc |
Immunosuppressant compounds and compositions
|
|
EP1726585A4
(en)
|
2004-03-05 |
2009-07-15 |
Banyu Pharma Co Ltd |
DIARYLSUBSTITUTED FIVE-GLOSS HETEROCYCLUS DERIVAT
|
|
GB0405289D0
(en)
|
2004-03-09 |
2004-04-21 |
Novartis Ag |
Organic compounds
|
|
AU2005230897B2
(en)
|
2004-04-02 |
2011-03-03 |
Merck Sharp & Dohme Corp. |
Asymmetric hydrogenation process useful for the preparation of cycloalkanoindole derivatives
|
|
WO2005123677A1
(en)
|
2004-06-16 |
2005-12-29 |
Actelion Pharmaceuticals Ltd |
4-carbonyl substituted 1,1,2-trimethyl-1a,4,5,5a-tetrahydro-1h-4-aza-cyclopropa'a!pentalene derivatives as agonists for the g-protein-coupled receptor s1p1/edg1 and immunosuppressive agents
|
|
EP1760071A4
(en)
|
2004-06-23 |
2008-03-05 |
Ono Pharmaceutical Co |
COMPOUND WITH S1P RECEPTOR BINDING ABILITY AND USE THEREOF
|
|
US7781617B2
(en)
|
2004-07-16 |
2010-08-24 |
Kyorin Pharmaceutical Co., Ltd |
Effective use method of medicaments and method of preventing expression of side effect
|
|
JP2007284350A
(ja)
|
2004-07-27 |
2007-11-01 |
Takeda Chem Ind Ltd |
糖尿病治療剤
|
|
WO2006010379A1
(en)
|
2004-07-29 |
2006-02-02 |
Actelion Pharmaceuticals Ltd. |
Novel thiophene derivatives as immunosuppressive agents
|
|
TW200611687A
(en)
|
2004-07-29 |
2006-04-16 |
Sankyo Co |
Pharmaceutical compositions used for immunosuppressant
|
|
EP1798226A4
(en)
|
2004-08-04 |
2009-06-17 |
Taisho Pharmaceutical Co Ltd |
TRAIZOL DERIVATIVE
|
|
RU2007109207A
(ru)
|
2004-08-13 |
2008-09-20 |
Прикис Фамэсьютикэлс, Инк. (US) |
Соединения-модуляторы активности рецептора сфингозин-1-фосфата (варианты), фармацевтическая композиция, содержащая указанные соединения, и способ лечения нарушения, ассоциированного со сфингозин-1-фосфатом
|
|
US20060223866A1
(en)
|
2004-08-13 |
2006-10-05 |
Praecis Pharmaceuticals, Inc. |
Methods and compositions for modulating sphingosine-1-phosphate (S1P) receptor activity
|
|
CA2577413A1
(en)
*
|
2004-09-23 |
2006-03-30 |
Wyeth |
Carbazole and cyclopentaindole derivatives to treat infection with hepatitis c virus
|
|
JP2008515987A
(ja)
|
2004-10-12 |
2008-05-15 |
フォーブス メディ−テック（リサーチ） インコーポレーテッド |
インシュリン抵抗性及び心筋ミオパチーを治療する化合物及び方法
|
|
WO2006047195A2
(en)
|
2004-10-22 |
2006-05-04 |
Merck & Co., Inc. |
2-(aryl)azacyclylmethyl carboxylates, sulfonates, phosphonates, phosphinates and heterocycles as s1p receptor agonists
|
|
DK1650186T3
(da)
|
2004-10-22 |
2008-10-13 |
Sun Pharmaceutical Ind Ltd |
Nye dicarboxylsyrederivater
|
|
CA2588766A1
(en)
|
2004-11-18 |
2006-05-26 |
The Institutes For Pharmaceutical Discovery, Llc |
Heterocycle substituted carboxylic acids
|
|
JPWO2006057448A1
(ja)
|
2004-11-26 |
2008-06-05 |
武田薬品工業株式会社 |
アリールアルカン酸誘導体
|
|
WO2006063033A2
(en)
|
2004-12-06 |
2006-06-15 |
University Of Virginia Patent Foundation |
Aryl amide sphingosine 1-phosphate analogs
|
|
EP2371811B1
(en)
|
2004-12-13 |
2014-10-08 |
Ono Pharmaceutical Co., Ltd. |
Azetidinecarboxylic acid derivative and medicinal use thereof
|
|
DE112005003337T5
(de)
|
2005-01-25 |
2008-02-21 |
Merck Patent Gmbh |
Mesogene Verbindungen, Flüssigkristallmedium und Flüssigkristallanzeige
|
|
JP2008530135A
(ja)
|
2005-02-14 |
2008-08-07 |
ユニバーシティ オブ バージニア パテント ファンデーション |
アミノ基およびフェニル基で置換されたシクロアルカンならびに５員の複素環を含むスフィンゴシン＝１−リン酸アゴニスト
|
|
DE602006003642D1
(en)
|
2005-03-23 |
2008-12-24 |
Actelion Pharmaceuticals Ltd |
Neue thiophen-derivate als sphingosin-1-phosphat-1-rezeptorantagonisten
|
|
WO2006100631A1
(en)
|
2005-03-23 |
2006-09-28 |
Actelion Pharmaceuticals Ltd |
Hydrogenated benzo (c) thiophene derivatives as immunomodulators
|
|
ES2370791T3
(es)
|
2005-03-23 |
2011-12-22 |
Actelion Pharmaceuticals Ltd. |
Nuevos derivados de tiofeno como agonistas del receptor de esfingosina-1-fosfato-1.
|
|
EP1893591A1
(en)
|
2005-06-08 |
2008-03-05 |
Novartis AG |
POLYCYCLIC OXADIAZOLES OR I SOXAZOLES AND THEIR USE AS SlP RECEPTOR LIGANDS
|
|
CA2612661A1
(en)
|
2005-06-24 |
2006-12-28 |
Actelion Pharmaceuticals Ltd. |
Novel thiophene derivatives
|
|
TWI418350B
(zh)
|
2005-06-24 |
2013-12-11 |
Sankyo Co |
含有ｐｐａｒ調節劑之醫藥組成物的用途
|
|
US20070060573A1
(en)
|
2005-08-10 |
2007-03-15 |
Lars Wortmann |
Acyltryptophanols
|
|
CA2619101A1
(en)
|
2005-08-23 |
2007-03-01 |
Irm Llc |
Immunosuppressant compounds and compositions
|
|
WO2007037196A1
(ja)
|
2005-09-29 |
2007-04-05 |
Yamamoto Chemicals, Inc. |
インドリン系化合物及びその製造方法
|
|
EP1965807A4
(en)
|
2005-11-23 |
2010-10-27 |
Epix Delaware Inc |
S1P RECEPTOR MODULATING COMPOUNDS AND THEIR USE
|
|
AR057894A1
(es)
|
2005-11-23 |
2007-12-26 |
Actelion Pharmaceuticals Ltd |
Derivados de tiofeno
|
|
TWI404706B
(zh)
|
2006-01-11 |
2013-08-11 |
Actelion Pharmaceuticals Ltd |
新穎噻吩衍生物
|
|
TW200736234A
(en)
|
2006-01-17 |
2007-10-01 |
Astrazeneca Ab |
Chemical compounds
|
|
CN101370805B
(zh)
|
2006-01-24 |
2011-04-27 |
埃科特莱茵药品有限公司 |
吡啶衍生物
|
|
GB0601744D0
(en)
|
2006-01-27 |
2006-03-08 |
Novartis Ag |
Organic compounds
|
|
TWI389683B
(zh)
|
2006-02-06 |
2013-03-21 |
Kyorin Seiyaku Kk |
A therapeutic agent for an inflammatory bowel disease or an inflammatory bowel disease treatment using a 2-amino-1,3-propanediol derivative as an active ingredient
|
|
TW200806611A
(en)
|
2006-02-09 |
2008-02-01 |
Daiichi Seiyaku Co |
Novel amidopropionic acid derivatives and medicine containing the same
|
|
WO2007092638A1
(en)
|
2006-02-09 |
2007-08-16 |
University Of Virginia Patent Foundation |
Bicyclic sphingosine 1-phosphate analogs
|
|
US20070191371A1
(en)
|
2006-02-14 |
2007-08-16 |
Kalypsys, Inc. |
Heterocyclic modulators of ppar
|
|
EP1984334B1
(en)
|
2006-02-15 |
2014-04-09 |
Allergan, Inc. |
Indole-3-carboxylic acid amide, ester, thioamide and thiol ester compounds bearing aryl or heteroaryl groups having sphingosine-1-phosphate (s1p) receptor antagonist biological activity
|
|
CN101460458A
(zh)
|
2006-02-15 |
2009-06-17 |
阿勒根公司 |
具有1－磷酸－鞘氨醇(s1p)受体拮抗剂生物活性的带芳基或者杂芳基基团的吲哚－3－羧酸的酰胺、酯、硫代酰胺和硫羟酸酯化合物
|
|
RU2008137553A
(ru)
|
2006-02-21 |
2010-03-27 |
Юниверсити Оф Вирджиния Пэтент Фаундейшн (Us) |
Фенил-циклоалкильные соединения, содержащие гетероциклические структуры
|
|
US7649098B2
(en)
|
2006-02-24 |
2010-01-19 |
Lexicon Pharmaceuticals, Inc. |
Imidazole-based compounds, compositions comprising them and methods of their use
|
|
CA2646430A1
(en)
|
2006-03-14 |
2007-09-20 |
Amgen Inc. |
Bicyclic carboxylic acid derivatives useful for treating metabolic disorders
|
|
TW200806633A
(en)
|
2006-03-21 |
2008-02-01 |
Epix Pharm Inc |
S1P receptor modulating compounds and use thereof
|
|
JP2007262009A
(ja)
|
2006-03-29 |
2007-10-11 |
Dai Ichi Seiyaku Co Ltd |
ヘテロアリール低級カルボン酸誘導体
|
|
TWI382984B
(zh)
|
2006-04-03 |
2013-01-21 |
Astellas Pharma Inc |
雜環化合物
|
|
GB0607389D0
(en)
|
2006-04-12 |
2006-05-24 |
Novartis Ag |
Organic compounds
|
|
US20090324581A1
(en)
|
2006-05-09 |
2009-12-31 |
Daiichi Sankyo Company Limited |
Heteroarylamide lower carboxylic acid derivative
|
|
EA200802058A1
(ru)
|
2006-05-09 |
2009-06-30 |
Пфайзер Продактс Инк. |
Производные циклоалкиламинокислот и их фармацевтические композиции
|
|
WO2007129473A1
(ja)
|
2006-05-09 |
2007-11-15 |
Daiichi Sankyo Company, Limited |
二環性アリール誘導体
|
|
EP2046766A1
(en)
|
2006-08-01 |
2009-04-15 |
Praecis Pharmaceuticals Incorporated |
Agonists of the sphingosine- 1- phosphate receptor (slp)
|
|
AR062156A1
(es)
|
2006-08-01 |
2008-10-22 |
Praecis Pharm Inc |
Compuestos agonistas y selectivos del receptor s1p-1
|
|
WO2008019090A2
(en)
|
2006-08-04 |
2008-02-14 |
Praecis Pharmaceuticals Incorporated |
Agonists of the sphingosine-1-phosphate receptor
|
|
SG174028A1
(en)
|
2006-08-08 |
2011-09-29 |
Kyorin Seiyaku Kk |
Aminophosphoric acid ester derivative and s1p receptor modulator containing the same as active ingredient
|
|
WO2008024196A1
(en)
|
2006-08-24 |
2008-02-28 |
Praecis Pharmaceuticals Incorporated |
Chemical compounds
|
|
JP2009269819A
(ja)
|
2006-08-25 |
2009-11-19 |
Asahi Kasei Pharma Kk |
アミン化合物
|
|
BRPI0716815A2
(pt)
|
2006-09-07 |
2013-11-05 |
Allergan Inc |
Co posto heteroatomáticos tendo atividade biológia agonista e/ou antagonista de receptor de esfinfosina-1-fosfato (s1p)
|
|
TWI408139B
(zh)
|
2006-09-07 |
2013-09-11 |
Actelion Pharmaceuticals Ltd |
新穎噻吩衍生物
|
|
AU2007292993B2
(en)
|
2006-09-07 |
2013-01-24 |
Idorsia Pharmaceuticals Ltd |
Pyridin-4-yl derivatives as immunomodulating agents
|
|
AU2007293653B2
(en)
|
2006-09-08 |
2011-02-17 |
Novartis Ag |
N-biaryl (hetero) arylsulphonamide derivatives useful in the treatment of diseases mediated by lymphocytes interactions
|
|
MX2009002915A
(es)
|
2006-09-21 |
2009-03-31 |
Actelion Pharmaceuticals Ltd |
Derivados de fenilo y su uso como inmunomoduladores.
|
|
CN101562977A
(zh)
|
2006-12-15 |
2009-10-21 |
艾博特公司 |
新的二唑化合物
|
|
GB0625648D0
(en)
|
2006-12-21 |
2007-01-31 |
Glaxo Group Ltd |
Compounds
|
|
JO2701B1
(en)
|
2006-12-21 |
2013-03-03 |
جلاكسو جروب ليميتد |
Vehicles
|
|
CA2672727A1
(en)
|
2006-12-21 |
2008-07-03 |
Abbott Laboratories |
Sphingosine-1-phosphate receptor agonist and antagonist compounds
|
|
JP2010515750A
(ja)
|
2007-01-11 |
2010-05-13 |
アラーガン インコーポレイテッド |
スフィンゴシン−１−ホスフェート（ｓ１ｐ）受容体アンタゴニスト生物活性を有する６−置換インドール−３−カルボン酸アミド化合物
|
|
WO2008091967A1
(en)
|
2007-01-26 |
2008-07-31 |
Smithkline Beecham Corporation |
Chemical compounds
|
|
WO2008097819A2
(en)
|
2007-02-05 |
2008-08-14 |
Smithkline Beecham Corporation |
Chemical compounds
|
|
NZ580454A
(en)
|
2007-03-16 |
2011-05-27 |
Actelion Pharmaceuticals Ltd |
Amino- pyridine derivatives as s1p1 /edg1 receptor agonists
|
|
CA2679980A1
(en)
|
2007-03-21 |
2007-09-27 |
Epix Pharmaceuticals, Inc. |
S1p receptor modulating compounds and use thereof
|
|
BRPI0809472A2
(pt)
|
2007-04-19 |
2014-09-09 |
Glaxo Group Ltd |
Derivados indazol substituídos com oxadiazol para emprego como agonistas de esfingosina 1-fosfato (sip)
|
|
EP2014653A1
(en)
|
2007-06-15 |
2009-01-14 |
Bioprojet |
Novel dicarboxylic acid derivatives as S1P1 receptor agonists
|
|
WO2009011850A2
(en)
|
2007-07-16 |
2009-01-22 |
Abbott Laboratories |
Novel therapeutic compounds
|
|
WO2009019506A1
(en)
|
2007-08-03 |
2009-02-12 |
Astrazeneca Ab |
Heterocyclyc sulfonamides having edg-1 antagonistic activity
|
|
US8399448B2
(en)
|
2007-08-08 |
2013-03-19 |
Merck Serono Sa |
6-amino-pyrimidine-4-carboxamide derivatives and related compounds which bind to the sphingosine 1-phosphate (S1P) receptor for the treatment of multiple sclerosis
|
|
TW200930368A
(en)
|
2007-11-15 |
2009-07-16 |
Astrazeneca Ab |
Bis-(sulfonylamino) derivatives in therapy
|
|
EP2222668B1
(en)
|
2007-12-18 |
2011-11-02 |
Arena Pharmaceuticals, Inc. |
Tetrahydrocyclopenta[b]indol-3-yl carboxylic acid derivatives useful in the treatment of autoimmune and inflammatory disorders
|
|
AU2009206733A1
(en)
|
2008-01-25 |
2009-07-30 |
Arena Pharmaceuticals, Inc. |
Dihydro- 1H- pyrrolo [1,2-a] indol-1-yl carboxylic derivatives which act as S1P1 agonists
|
|
AR070398A1
(es)
|
2008-02-22 |
2010-03-31 |
Gruenenthal Chemie |
Derivados sustituidos de indol
|
|
AU2009258242B2
(en)
|
2008-05-14 |
2015-07-16 |
The Scripps Research Institute |
Novel modulators of sphingosine phosphate receptors
|
|
WO2009151621A1
(en)
|
2008-06-13 |
2009-12-17 |
Arena Pharmaceuticals, Inc. |
Substituted (1, 2, 4-0xadiaz0l-3-yl) indolin-1-yl carboxylic acid derivatives useful as s1p1 agonists
|
|
WO2009151626A1
(en)
|
2008-06-13 |
2009-12-17 |
Arena Pharmaceuticals, Inc. |
Substituted (1, 2, 4-0xadiaz0l-3-yl) indolin-1-yl carboxylic acid derivatives useful as s1p1 agonists
|
|
KR20190004843A
(ko)
|
2008-07-23 |
2019-01-14 |
아레나 파마슈티칼스, 인크. |
자가면역성 및 염증성의 장애의 치료에 유용한 치환된 1,2,3,4-테트라히드로시클로펜타[ｂ]인돌-3-일)아세트산 유도체
|
|
JP5726737B2
(ja)
|
2008-08-27 |
2015-06-03 |
アリーナ ファーマシューティカルズ， インコーポレイテッド |
自己免疫障害および免疫性障害の治療において有用なｓ１ｐ１受容体のアゴニストとしての置換三環式酸誘導体
|
|
US20100216762A1
(en)
|
2009-02-10 |
2010-08-26 |
Abbott Laboratories |
Agonists and Antagonists of the S1P5 Receptor, and Methods of Use Thereof
|
|
WO2011005290A1
(en)
|
2009-06-23 |
2011-01-13 |
Arena Pharmaceuticals, Inc. |
Disubstituted oxadiazole derivatives useful in the treatment of autoimmune and inflammatory disorders
|
|
WO2011005295A1
(en)
|
2009-06-24 |
2011-01-13 |
Arena Pharmaceuticals, Inc. |
Modulators of the sphingosine-1-phosphate (s1p) receptor useful for the treatment of disorders related thereto
|
|
WO2011059784A1
(en)
|
2009-10-29 |
2011-05-19 |
Bristol-Myers Squibb Company |
Tricyclic heterocyclic compounds
|
|
CN108558740B
(zh)
|
2010-01-27 |
2021-10-19 |
艾尼纳制药公司 |
S1p1受体调节剂及其盐的制备方法
|
|
CA2789480A1
(en)
|
2010-03-03 |
2011-09-09 |
Arena Pharmaceuticals, Inc. |
Processes for the preparation of s1p1 receptor modulators and crystalline forms thereof
|
|
WO2012015758A2
(en)
|
2010-07-30 |
2012-02-02 |
Saint Louis University |
Methods of treating pain
|