JP2009530281A - 代謝障害の治療に有用である二環式カルボン酸誘導体 - Google Patents

代謝障害の治療に有用である二環式カルボン酸誘導体 Download PDF

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JP2009530281A
JP2009530281A JP2009500426A JP2009500426A JP2009530281A JP 2009530281 A JP2009530281 A JP 2009530281A JP 2009500426 A JP2009500426 A JP 2009500426A JP 2009500426 A JP2009500426 A JP 2009500426A JP 2009530281 A JP2009530281 A JP 2009530281A
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シヤルマ，ラジブ
アケルマン，ミツシエル
カルドソ，マリオ・ヘ
ハウズ，ジヨナサン・ビー
リー，アン−ロン
リウ，チンチアン
リウ，ジウエン
マ，チーホワ
メデイナ，ジユリオ・シー
シユミツト，マイケル・ジエイ
スン，イン
ワン，インツアイ
ワン，ジヨンユイ
チユー，リウシヨン
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アムジエン・インコーポレーテツド
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  • Organic Chemistry (AREA)
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  • Diabetes (AREA)
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  • Obesity (AREA)
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  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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  • Ophthalmology & Optometry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Indole Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Pyrane Compounds (AREA)
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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2009500426A 2006-03-14 2007-03-12 代謝障害の治療に有用である二環式カルボン酸誘導体 Withdrawn JP2009530281A (ja)

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US78270606P 2006-03-14 2006-03-14
US90520707P 2007-03-05 2007-03-05
PCT/US2007/006279 WO2007106469A2 (en) 2006-03-14 2007-03-12 Bicyclic carboxylic acid derivatives useful for treating metabolic disorders

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JP2009530281A true JP2009530281A (ja) 2009-08-27
JP2009530281A5 JP2009530281A5 (https=) 2010-04-22

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US (1) US20070244155A1 (https=)
EP (1) EP2001844A2 (https=)
JP (1) JP2009530281A (https=)
AR (1) AR059895A1 (https=)
AU (1) AU2007225208A1 (https=)
CA (1) CA2646430A1 (https=)
MX (1) MX2008011615A (https=)
TW (1) TW200804333A (https=)
WO (1) WO2007106469A2 (https=)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013528647A (ja) * 2010-06-16 2013-07-11 メタボレックス， インコーポレイテッド Ｇｐｒ１２０受容体作動薬及びその使用
JP2015503595A (ja) * 2012-01-12 2015-02-02 ジエンス ヘンルイ メデイシンカンパニー リミテッドＪｉａｎｇｓｕ Ｈｅｎｇｒｕｉ Ｍｅｄｉｃｉｎｅ Ｃｏ．，Ｌｔｄ． 多環式化合物誘導体、それらの製造方法および医薬用途
JP2016508506A (ja) * 2013-02-06 2016-03-22 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 新しいインダニルオキシジヒドロベンゾフラニル酢酸
JP2016513135A (ja) * 2013-02-28 2016-05-12 エスケー ケミカルズ カンパニー リミテッド 三環式化合物およびその使用
JP2019522043A (ja) * 2016-05-23 2019-08-08 中国医学科学院薬物研究所Ｉｎｓｔｉｔｕｔｅ Ｏｆ Ｍａｔｅｒｉａ Ｍｅｄｉｃａ， Ｃｈｉｎｅｓｅ Ａｃａｄｅｍｙ Ｏｆ Ｍｅｄｉｃａｌ Ｓｃｉｅｎｃｅｓ フェニレート誘導体、調製及び医薬組成物及び使用
JP2020512387A (ja) * 2017-03-31 2020-04-23 武田薬品工業株式会社 代謝性障害の治療の為の置換シクリル酢酸誘導体

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WO2006088246A1 (ja) * 2005-02-18 2006-08-24 Takeda Pharmaceutical Company Limited Ｇｐｒ３４受容体機能調節剤
CA2662242C (en) * 2006-09-07 2012-06-12 Amgen Inc. Benzo-fused compounds for use in treating metabolic disorders
EP2064193A1 (en) * 2006-09-07 2009-06-03 Amgen, Inc Heterocyclic gpr40 modulators
AU2008241490B2 (en) * 2007-04-16 2011-07-21 Amgen Inc. Substituted biphenyl phenoxy-, thiophenyl- and aminophenylpropanoic acid GPR40 modulators
EP2025674A1 (de) 2007-08-15 2009-02-18 sanofi-aventis Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
US8030354B2 (en) 2007-10-10 2011-10-04 Amgen Inc. Substituted biphenyl GPR40 modulators
EP2215068B1 (en) * 2007-10-29 2012-06-13 Merck Sharp & Dohme Corp. Antidiabetic tricyclic compounds
WO2009111056A1 (en) * 2008-03-06 2009-09-11 Amgen Inc. Conformationally constrained carboxylic acid derivatives useful for treating metabolic disorders
US8580841B2 (en) * 2008-07-23 2013-11-12 Arena Pharmaceuticals, Inc. Substituted 1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid derivatives useful in the treatment of autoimmune and inflammatory disorders
JP2012503595A (ja) * 2008-07-28 2012-02-09 シダンスク ユニバーシティ 代謝病の治療用の化合物
HRP20160890T1 (hr) * 2008-08-27 2016-09-23 Arena Pharmaceuticals, Inc. Derivati supstituirane tricikličke kiseline kao agonisti s1p1-receptora korisni u liječenju autoimunih i upalnih poremećaja
AU2009303475B2 (en) * 2008-10-15 2012-09-13 Amgen Inc. Spirocyclic GPR40 modulators
EA022417B1 (ru) * 2008-10-21 2015-12-30 Саймабэй Терапевтикс, Инк. Арильные агонисты рецептора gpr120 и их применение
AR074760A1 (es) * 2008-12-18 2011-02-09 Metabolex Inc Agonistas del receptor gpr120 y usos de los mismos en medicamentos para el tratamiento de diabetes y el sindrome metabolico.
WO2010085525A1 (en) * 2009-01-23 2010-07-29 Schering Corporation Bridged and fused heterocyclic antidiabetic compounds
CN102421739A (zh) * 2009-04-22 2012-04-18 安斯泰来制药株式会社 羧酸化合物
JP5856980B2 (ja) 2010-01-27 2016-02-10 アリーナ ファーマシューティカルズ， インコーポレイテッド （Ｒ）−２−（７−（４−シクロペンチル−３−（トリフルオロメチル）ベンジルオキシ）−１，２，３，４−テトラヒドロシクロペンタ［ｂ］インドール−３−イル）酢酸およびその塩の調製のためのプロセス
WO2011107494A1 (de) 2010-03-03 2011-09-09 Sanofi Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
CN105503882B (zh) 2010-03-03 2019-07-05 艾尼纳制药公司 制备s1p1受体调节剂及其晶体形式的方法
EP2582709B1 (de) 2010-06-18 2018-01-24 Sanofi Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
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