|
US4482571A
(en)
|
1982-06-21 |
1984-11-13 |
University Of Pittsburgh |
Sickle cell anemia treatment and compound
|
|
GB8524157D0
(en)
|
1984-10-19 |
1985-11-06 |
Ici America Inc |
Heterocyclic amides
|
|
GB8607294D0
(en)
|
1985-04-17 |
1986-04-30 |
Ici America Inc |
Heterocyclic amide derivatives
|
|
NZ217961A
(en)
|
1985-10-17 |
1990-06-26 |
Ici America Inc |
Indole and indazole derivatives and pharmaceutical compositions thereof
|
|
US4964895A
(en)
|
1987-06-08 |
1990-10-23 |
Monsanto Company |
Substituted 4-(4-nitrophenoxy) pyrazoles and their use as herbicides
|
|
US4997815A
(en)
*
|
1988-11-01 |
1991-03-05 |
Children's Hospital Medical Center Of Northern California |
Method for augmenting fetal hemoglobin by treatment with activin and/or inhibin
|
|
EP0457803A4
(en)
|
1989-02-08 |
1991-12-04 |
Abbott Laboratories |
4-hydroxythiazoles as 5-lipoxygenase inhibitors
|
|
US5216004A
(en)
|
1990-09-13 |
1993-06-01 |
Children's Hospital Medical Center Of North California |
Method for preventing malaria
|
|
US5656644A
(en)
|
1994-07-20 |
1997-08-12 |
Smithkline Beecham Corporation |
Pyridyl imidazoles
|
|
US5439939A
(en)
|
1992-03-17 |
1995-08-08 |
Children's Hospital Medical Center Of Northern California |
Pharmaceutical compositions and methods using isobutyramide for treating betaglobin disorders
|
|
WO1995011699A1
(en)
*
|
1993-10-29 |
1995-05-04 |
The Trustees Of Boston University |
Physiologically stable compositions of butyric acid, and butyric acid salts and derivatives as anti-neoplastic agents
|
|
CA2175249A1
(en)
|
1993-11-10 |
1995-05-18 |
Harold L. Newmark |
Butyric ester cyto-differentiating agents
|
|
US5569675A
(en)
|
1994-03-07 |
1996-10-29 |
Bar Ilan University |
Methods of using carboxylic acid esters to increase fetal-hemoglobin levels
|
|
WO1995028637A1
(en)
*
|
1994-04-13 |
1995-10-26 |
Beckman Instruments, Inc. |
Analysis of analytes in biological fluids
|
|
US6071923A
(en)
|
1994-09-16 |
2000-06-06 |
Bar-Ilan University |
Retinoyloxy aryl-substituted alkylene butyrates useful for the treatment of cancer and other proliferative diseases
|
|
US6040342A
(en)
*
|
1994-09-16 |
2000-03-21 |
Bar-Ilan University |
Retinoyloxy (alkyl-substituted) methyl butyrates useful for the treatment of cancer and other proliferative diseases
|
|
US5789434A
(en)
|
1994-11-15 |
1998-08-04 |
Bayer Corporation |
Derivatives of substituted 4-biarylbutyric acid as matrix metalloprotease inhibitors
|
|
US6011000A
(en)
*
|
1995-03-03 |
2000-01-04 |
Perrine; Susan P. |
Compositions for the treatment of blood disorders
|
|
US5700826A
(en)
|
1995-06-07 |
1997-12-23 |
Ontogen Corporation |
1,2,4,5-tetra substituted imidazoles as modulators of multi-drug resistance
|
|
JP3964478B2
(ja)
|
1995-06-30 |
2007-08-22 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
ヘテロ環含有カルボン酸誘導体及びそれを含有する医薬
|
|
US6110697A
(en)
|
1995-09-20 |
2000-08-29 |
Merck & Co., Inc. |
Histone deacetylase as target for antiprotozoal agents
|
|
US5922837A
(en)
|
1995-09-20 |
1999-07-13 |
Merck & Co., Inc. |
Antiprotozoal cyclic tetrapeptides
|
|
WO1997011366A1
(en)
|
1995-09-20 |
1997-03-27 |
Merck & Co., Inc. |
Histone deacetylase as target for antiprotozoal agents
|
|
US20030219832A1
(en)
|
1996-03-11 |
2003-11-27 |
Klein Elliott S. |
Synthesis and use of retinoid compounds having negative hormone and/or antagonist activities
|
|
US6777217B1
(en)
|
1996-03-26 |
2004-08-17 |
President And Fellows Of Harvard College |
Histone deacetylases, and uses related thereto
|
|
WO1997047307A1
(en)
|
1996-06-14 |
1997-12-18 |
The Uab Research Foundation |
Use of histone deacetylase inhibitors to activate transgene expression
|
|
AU3588097A
(en)
|
1996-07-02 |
1998-01-21 |
Bar-Ilan University |
Retinoyloxy(substituted)alkylene butyrates useful for the treatment of cancer and other proliferative diseases
|
|
US6197743B1
(en)
|
1996-07-26 |
2001-03-06 |
The Trustees Of Boston University |
Compositions and methods for the treatment of viral disorders
|
|
US5939456A
(en)
|
1996-07-26 |
1999-08-17 |
Perrine; Susan P. |
Pulsed administration of compositions for the treatment of blood disorders
|
|
EP0827742A1
(en)
|
1996-09-04 |
1998-03-11 |
Vrije Universiteit Brussel |
Use of histone deacetylase inhibitors for treating fribosis or cirrhosis
|
|
US6068987A
(en)
*
|
1996-09-20 |
2000-05-30 |
Merck & Co., Inc. |
Histone deacetylase as target for antiprotozoal agents
|
|
US6794392B1
(en)
*
|
1996-09-30 |
2004-09-21 |
Schering Aktiengesellschaft |
Cell differentiation inducer
|
|
JP3354090B2
(ja)
*
|
1996-09-30 |
2002-12-09 |
シエーリング アクチエンゲゼルシャフト |
分化誘導剤
|
|
US6174905B1
(en)
*
|
1996-09-30 |
2001-01-16 |
Mitsui Chemicals, Inc. |
Cell differentiation inducer
|
|
CZ225699A3
(cs)
|
1996-12-23 |
2000-09-13 |
Du Pont Pharmaceuticals Company |
Dusíkaté heteroaromatické sloučeniny jako inhibitory faktoru Xa
|
|
WO1998029114A1
(en)
|
1996-12-30 |
1998-07-09 |
Bar-Ilan University |
Tricarboxylic acid-containing oxyalkyl esters and uses thereof
|
|
US6130248A
(en)
|
1996-12-30 |
2000-10-10 |
Bar-Ilan University |
Tricarboxylic acid-containing oxyalkyl esters and uses thereof
|
|
US6235474B1
(en)
*
|
1996-12-30 |
2001-05-22 |
The Johns Hopkins University |
Methods and kits for diagnosing and determination of the predisposition for diseases
|
|
US7062219B2
(en)
|
1997-01-31 |
2006-06-13 |
Odyssey Thera Inc. |
Protein fragment complementation assays for high-throughput and high-content screening
|
|
US6124495A
(en)
|
1997-03-11 |
2000-09-26 |
Beacon Laboratories, Inc. |
Unsaturated oxyalkylene esters and uses thereof
|
|
US6030961A
(en)
*
|
1997-03-11 |
2000-02-29 |
Bar-Ilan Research & Development Co., Ltd. |
Oxyalkylene phosphate compounds and uses thereof
|
|
US6043389A
(en)
*
|
1997-03-11 |
2000-03-28 |
Mor Research Applications, Ltd. |
Hydroxy and ether-containing oxyalkylene esters and uses thereof
|
|
US5939455A
(en)
|
1997-03-11 |
1999-08-17 |
Beacon Laboratories, Inc. |
Therapeutic augmentation of oxyalkylene diesters and butyric acid derivatives
|
|
US6110955A
(en)
|
1997-03-11 |
2000-08-29 |
Beacon Laboratories, Inc. |
Metabolically stabilized oxyalkylene esters and uses thereof
|
|
US6110970A
(en)
|
1997-03-11 |
2000-08-29 |
Beacon Laboratories, Inc. |
Nitrogen-containing oxyalkylene esters and uses thereof
|
|
US6387673B1
(en)
*
|
1997-05-01 |
2002-05-14 |
The Salk Institute For Biological Studies |
Compounds useful for the modulation of processes mediated by nuclear hormone receptors, methods for the identification and use of such compounds
|
|
US6231880B1
(en)
*
|
1997-05-30 |
2001-05-15 |
Susan P. Perrine |
Compositions and administration of compositions for the treatment of blood disorders
|
|
AUPO721997A0
(en)
|
1997-06-06 |
1997-07-03 |
Queensland Institute Of Medical Research, The |
Anticancer compounds
|
|
AUPO864097A0
(en)
|
1997-08-19 |
1997-09-11 |
Peplin Pty Ltd |
Anti-cancer compounds
|
|
EP1010705A4
(en)
|
1997-09-02 |
2004-09-15 |
Sumitomo Pharma |
NEW CYCLIC TETRAPEPTIDE DERIVATIVES AND THEIR MEDICAL USE
|
|
WO1999023885A1
(en)
|
1997-11-10 |
1999-05-20 |
The Salk Institute For Biological Studies |
Methods for the use of inhibitors of co-repressors for the treatment of neoplastic diseases
|
|
US6884597B1
(en)
*
|
1998-01-20 |
2005-04-26 |
Medical & Biological Laboratories, Co., Ltd. |
Method for detecting acetyltransferase and deacetylase activities and method for screening inhibitors or enhancers of these enzymes
|
|
US6262116B1
(en)
|
1998-01-23 |
2001-07-17 |
Sloan-Kettering Institute For Cancer Research |
Transcription therapy for cancers
|
|
CA2324426A1
(en)
|
1998-02-11 |
1999-08-19 |
Douglas V. Faller |
Compositions and methods for the treatment of cystic fibrosis
|
|
US6287843B1
(en)
|
1998-04-03 |
2001-09-11 |
Pioneer Hi-Bred International, Inc. |
Maize histone deacetylases and their use
|
|
US6288063B1
(en)
|
1998-05-27 |
2001-09-11 |
Bayer Corporation |
Substituted 4-biarylbutyric and 5-biarylpentanoic acid derivatives as matrix metalloprotease inhibitors
|
|
US20030236204A1
(en)
*
|
2002-06-14 |
2003-12-25 |
Isis Pharmaceuticals Inc. |
Antisense modulation of histone deacetylase 2 expression
|
|
AUPP505798A0
(en)
|
1998-08-04 |
1998-08-27 |
Fujisawa Pharmaceutical Co., Ltd. |
Novel compound fr225497 substance
|
|
WO2000010583A1
(en)
|
1998-08-21 |
2000-03-02 |
Smithkline Beecham Corporation |
Human histone deacetylase gene hd4
|
|
IL142531A0
(en)
|
1998-10-13 |
2002-03-10 |
Fujisawa Pharmaceutical Co |
Cyclic peptide compound, processes for the preparation thereof and pharmaceutical compositions containing the same
|
|
JP2002527101A
(ja)
|
1998-10-16 |
2002-08-27 |
ノバルティス アクチエンゲゼルシャフト |
ヒストンデアセチラーゼ阻害剤による造血幹細胞への遺伝子形質導入の改良及び自己再生の促進
|
|
JP2002541762A
(ja)
*
|
1998-11-10 |
2002-12-10 |
ボード・オヴ・リージェンツ,ザ・ユニヴァーシティ・オヴ・テキサス・システム |
Mef2転写因子の阻害による心肥大および心不全の予防方法
|
|
US6287790B1
(en)
|
1998-11-30 |
2001-09-11 |
The Regents Of The University Of California |
Utilization of nuclear structural proteins for targeted therapy and detection of proliferative and differentiation disorders
|
|
US6335170B1
(en)
*
|
1999-02-22 |
2002-01-01 |
Torben F. Orntoft |
Gene expression in bladder tumors
|
|
JP4269041B2
(ja)
|
1999-03-02 |
2009-05-27 |
国立大学法人九州工業大学 |
新規な環状テトラペプチド誘導体とその医薬用途
|
|
WO2000056917A1
(en)
|
1999-03-23 |
2000-09-28 |
Chugai Research Institute For Molecular Medicine, Inc. |
Method for screening anticancer agent
|
|
US6518012B1
(en)
*
|
1999-04-02 |
2003-02-11 |
Health Research, Inc. |
Method for regulating the expression of MHC antigens and CD40 by inhibitors of histone deacetylation
|
|
DE60001229T2
(de)
|
1999-04-09 |
2003-10-30 |
Smithkline Beecham Corp., Philadelphia |
Triarylimidazole
|
|
JP2003500052A
(ja)
|
1999-05-03 |
2003-01-07 |
メチルジーン インコーポレイテッド |
ヒストン脱アセチル酵素の抑制
|
|
US20030078216A1
(en)
*
|
1999-05-03 |
2003-04-24 |
Macleod A. Robert |
Inhibition of histone deactylase
|
|
AU6109600A
(en)
|
1999-07-23 |
2001-02-13 |
Merck & Co., Inc. |
Apicidin-derived cyclic tetrapeptides
|
|
US20030078369A1
(en)
*
|
1999-07-23 |
2003-04-24 |
Meinke Peter T. |
Apicidin-derived cyclic tetrapeptides
|
|
WO2001014581A2
(en)
|
1999-08-20 |
2001-03-01 |
Board Of Regents, The University Of Texas System |
Hdac4 and hdac5 in the regulation of cardiac gene expression
|
|
JP2001081031A
(ja)
|
1999-08-30 |
2001-03-27 |
Schering Ag |
溶解性および経口吸収性を改善したベンズアミド誘導体含有製剤
|
|
WO2001017514A1
(en)
|
1999-09-03 |
2001-03-15 |
The Salk Institute For Biological Studies |
Modulation of gene expression by modulating histone acetylation
|
|
TR200201052T2
(tr)
|
1999-09-08 |
2003-01-21 |
Sloan-Kettering Institute For Cancer Research |
Yeni hücre farklılaştırıcı ajanlar sınıfı ve hıstone deacetylase inhibitörleri, ve burada kullanım yöntemleri
|
|
DE60034688T2
(de)
|
1999-09-08 |
2008-01-17 |
Sloan-Kettering Institute For Cancer Research |
Kristallstruktur einer deacetylase und deren inhibitoren
|
|
EP1222308A4
(en)
|
1999-10-08 |
2005-02-16 |
Merck & Co Inc |
INHIBITORS OF HISTONE ACETYL ANTIPROTOZOA TRANSFERASE
|
|
DK1233958T3
(da)
*
|
1999-11-23 |
2011-10-17 |
Methylgene Inc |
Hæmmere af histondeacetylase
|
|
JP2001149081A
(ja)
*
|
1999-11-29 |
2001-06-05 |
Cyclex Co Ltd |
脱アセチル化酵素の活性測定方法、並びにこれら酵素の阻害剤もしくは促進剤のスクリーニング方法
|
|
CA2291367A1
(en)
|
1999-12-06 |
2001-06-06 |
Isabelle Henry |
Genetic constructions having a reduced or an increased number of epigenetic control regions and methods of use thereof
|
|
ATE320484T1
(de)
|
1999-12-08 |
2006-04-15 |
Axys Pharm Inc |
Histone-deacetylase-8 proteine, nukleinsäuren und methoden zur verwendung
|
|
US6875598B1
(en)
*
|
1999-12-08 |
2005-04-05 |
Applera Corporation |
Histone deacetylase-8 proteins, nuclei acids, and methods for use
|
|
EP1438966B1
(en)
|
1999-12-08 |
2007-02-14 |
Cyclacel Pharmaceuticals, Inc. |
Use of depsipeptide and congeners thereof as immunosuppressants for treating an infectious disease, an autoimmune disease, allergic reactions or a hyperproliferative skin disease.
|
|
US6828302B1
(en)
|
1999-12-08 |
2004-12-07 |
Xcyte Therapies, Inc. |
Therapeutic uses of depsipeptides and congeners thereof
|
|
US7452664B2
(en)
|
1999-12-15 |
2008-11-18 |
Massachusetts Institute Of Technology |
Methods for identifying agents which alter histone protein acetylation
|
|
US6544957B2
(en)
*
|
2000-01-04 |
2003-04-08 |
The Johns Hopkins University |
Methods and reagents for facilitating transcription
|
|
US6689558B2
(en)
*
|
2000-02-08 |
2004-02-10 |
Sangamo Biosciences, Inc. |
Cells for drug discovery
|
|
DK1259485T3
(da)
|
2000-02-29 |
2006-04-10 |
Millennium Pharm Inc |
Benzamider og beslægtede inhibitorer for faktor Xa
|
|
US20030129724A1
(en)
|
2000-03-03 |
2003-07-10 |
Grozinger Christina M. |
Class II human histone deacetylases, and uses related thereto
|
|
GB0005199D0
(en)
|
2000-03-04 |
2000-04-26 |
Imp College Innovations Ltd |
Modulation of histone deacetylase
|
|
WO2001070675A2
(en)
|
2000-03-24 |
2001-09-27 |
Methylgene, Inc. |
Inhibitors of histone deacetylase
|
|
EP1268534A2
(en)
|
2000-03-24 |
2003-01-02 |
Filgen Biosciences, Inc. |
Peptides binding to non-acetylated h3 and h4 histones for cancer therapy
|
|
US20020137162A1
(en)
|
2000-03-24 |
2002-09-26 |
Zuomei Li |
Antisense oligonucleotide inhibition of specific histone deacetylase isoforms
|
|
WO2002008273A2
(en)
|
2000-07-21 |
2002-01-31 |
Millennium Pharmaceuticals, Inc. |
47508, a novel human histone deacetylase family member and uses thereof
|
|
GB0007217D0
(en)
|
2000-03-24 |
2000-05-17 |
Europ I Of Oncology |
Materials and methods relating to the treatment of leukaemias
|
|
JP2004533850A
(ja)
|
2000-03-24 |
2004-11-11 |
メチルジーン・インコーポレーテッド |
特異的なヒストン脱アセチル化酵素アイソフォームの阻害
|
|
GB0007405D0
(en)
|
2000-03-27 |
2000-05-17 |
Smithkline Beecham Corp |
Compounds
|
|
US6458589B1
(en)
*
|
2000-04-27 |
2002-10-01 |
Geron Corporation |
Hepatocyte lineage cells derived from pluripotent stem cells
|
|
EP1170008A1
(en)
|
2000-07-07 |
2002-01-09 |
Chemotherapeutisches Forschungsinstitut Georg-Speyer-Haus |
Valproic acid and derivatives thereof as histone deacetylase inhibitors
|
|
WO2002006307A1
(en)
|
2000-07-17 |
2002-01-24 |
Fujisawa Pharmaceutical Co., Ltd. |
Reduced fk228 and use thereof
|
|
CN1466572A
(zh)
|
2000-07-28 |
2004-01-07 |
ס����ҩ��ʽ���� |
吡咯衍生物
|
|
EP1182263A1
(en)
|
2000-08-11 |
2002-02-27 |
Evotec OAI AG |
Process for detecting threonine/serine kinase activity
|
|
US6673587B1
(en)
*
|
2000-08-11 |
2004-01-06 |
The Salk Institute For Biological Studies |
Histone deacetylase, and uses therefor
|
|
WO2002015921A2
(en)
|
2000-08-18 |
2002-02-28 |
The Governement Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services |
Methods of treating cutaneous and peripheral t-cell lymphoma by a histone deacetylase inhibitor
|
|
PE20020354A1
(es)
*
|
2000-09-01 |
2002-06-12 |
Novartis Ag |
Compuestos de hidroxamato como inhibidores de histona-desacetilasa (hda)
|
|
WO2002022133A1
(en)
|
2000-09-12 |
2002-03-21 |
Virginia Commonwealth University |
Promotion of adoptosis in cancer cells by co-administration of cyclin dependent kinase inhibitors and cellular differentiation agents
|
|
US6538030B2
(en)
*
|
2000-09-20 |
2003-03-25 |
Yih-Lin Chung |
Treating radiation fibrosis
|
|
EP2292593A3
(en)
|
2000-09-29 |
2011-05-25 |
TopoTarget UK Limited |
Carbamic acid compounds comprising a sulfonamide linkage as HDAC inhibitors
|
|
GB0023983D0
(en)
|
2000-09-29 |
2000-11-15 |
Prolifix Ltd |
Therapeutic compounds
|
|
EP2083005A1
(en)
|
2000-09-29 |
2009-07-29 |
TopoTarget UK Limited |
Carbamic acid compounds comprising an amide linkage as HDAC inhibitors
|
|
WO2002030970A2
(en)
|
2000-10-13 |
2002-04-18 |
Bayer Aktiengesellschaft |
Human histone deacetylase gene
|
|
DE10053474A1
(de)
|
2000-10-24 |
2002-05-02 |
Schering Ag |
Schwefelhaltige Indirubinderivate, deren Herstellung und Verwendung
|
|
US20020103192A1
(en)
|
2000-10-26 |
2002-08-01 |
Curtin Michael L. |
Inhibitors of histone deacetylase
|
|
WO2002036783A2
(en)
|
2000-10-31 |
2002-05-10 |
Bayer Aktiengesellschaft |
Regulation of human histone deacetylase
|
|
EP1335920B1
(en)
|
2000-11-02 |
2013-04-03 |
Sloan-Kettering Institute For Cancer Research |
Compositions containing purine derivatives for binding to hsp90
|
|
AU2002243231A1
(en)
*
|
2000-11-21 |
2002-07-24 |
Wake Forest University |
Method of treating autoimmune diseases
|
|
DE10061162A1
(de)
|
2000-11-30 |
2002-07-11 |
Schering Ag |
Aryl-substituierte Indirubinderivate, deren Herstellung und Verwendung
|
|
AR035659A1
(es)
|
2000-12-07 |
2004-06-23 |
Hoffmann La Roche |
Hidroxiamidas de acido (1-oxo-1,2,3,4-tetrahidro-naftalen-2-il)-alcanoico, proceso para la manufactura de estos compuestos, composiciones farmaceuticas que contienen dichos compuestos y los usos de los mismos
|
|
US20040005574A1
(en)
*
|
2002-07-08 |
2004-01-08 |
Leonard Guarente |
SIR2 activity
|
|
US6376508B1
(en)
*
|
2000-12-13 |
2002-04-23 |
Academia Sinica |
Treatments for spinal muscular atrophy
|
|
AU2002230997A1
(en)
|
2000-12-15 |
2002-06-24 |
Genetics Institute, Llc |
Methods and compositions for diagnosing and treating rheumatoid arthritis
|
|
US20050171042A1
(en)
|
2000-12-19 |
2005-08-04 |
Monia Brett P. |
Compositions and their uses directed to binding proteins
|
|
US20040204373A1
(en)
|
2000-12-19 |
2004-10-14 |
Isis Pharmaceuticals Inc. |
Antisense modulation of histone deacetylase I expression
|
|
WO2002050285A2
(en)
|
2000-12-20 |
2002-06-27 |
Novartis Ag |
Histone deacetylase-related gene and protein
|
|
US6693132B2
(en)
|
2000-12-21 |
2004-02-17 |
Beacon Laboratories, Inc. |
Methods for using alkanoyloxymethyl esters
|
|
US6720445B2
(en)
*
|
2000-12-21 |
2004-04-13 |
Beacon Laboratories, Inc. |
Acetyloxymethyl esters and methods for using the same
|
|
US6562995B1
(en)
|
2000-12-21 |
2003-05-13 |
Beacon Laboratories, Inc. |
Delta dicarbonyl compounds and methods for using the same
|
|
KR100456047B1
(ko)
*
|
2000-12-22 |
2004-11-08 |
이인원 |
애피시딘 유도체, 이의 합성방법 및 이를 포함하는 항암제조성물
|
|
AR035513A1
(es)
|
2000-12-23 |
2004-06-02 |
Hoffmann La Roche |
Derivados de tetrahidropiridina, proceso para prepararlos, composiciones farmaceuticas que los contienen, y uso de dichos compuestos en la preparacion de medicamentos
|
|
WO2002055688A2
(en)
|
2001-01-10 |
2002-07-18 |
Us Gov Health & Human Serv |
Histone deacetylase inhibitors in diagnosis and treatment of thyroid neoplasms
|
|
CA2434601A1
(en)
|
2001-01-12 |
2002-09-12 |
Methylgene, Inc. |
Methods for specifically inhibiting histone deacetylase-4
|
|
US20030152557A1
(en)
|
2001-01-12 |
2003-08-14 |
Besterman Jeffrey M. |
Methods for inhibiting histone deacetylase-4
|
|
US20030148970A1
(en)
|
2001-01-12 |
2003-08-07 |
Besterman Jeffrey M. |
Methods for specifically inhibiting histone deacetylase-4
|
|
US6756200B2
(en)
*
|
2001-01-26 |
2004-06-29 |
The Johns Hopkins University School Of Medicine |
Aberrantly methylated genes as markers of breast malignancy
|
|
AR035417A1
(es)
*
|
2001-01-27 |
2004-05-26 |
Hoffmann La Roche |
Derivados triciclicos de lactama y sultama, procesos para su elaboracion, medicamentos que los contienen, y el uso de dichos compuestos en la preparacion de medicamentos
|
|
US20020183388A1
(en)
|
2001-02-01 |
2002-12-05 |
Gudas Lorraine J. |
Use of retinoids plus histone deacetylase inhibitors to inhibit the growth of solid tumors
|
|
WO2002070675A2
(en)
*
|
2001-02-05 |
2002-09-12 |
Bayer Aktiengesellschaft |
Regulation of human histone acetyltransferase
|
|
US20020177594A1
(en)
|
2001-03-14 |
2002-11-28 |
Curtin Michael L. |
Inhibitors of histone deacetylase
|
|
US6495719B2
(en)
*
|
2001-03-27 |
2002-12-17 |
Circagen Pharmaceutical |
Histone deacetylase inhibitors
|
|
US8026280B2
(en)
|
2001-03-27 |
2011-09-27 |
Errant Gene Therapeutics, Llc |
Histone deacetylase inhibitors
|
|
US7214831B2
(en)
*
|
2002-05-22 |
2007-05-08 |
Errant Gene Therapeutics, Llc |
Histone deacetylase inhibitors based on alpha-chalcogenmethylcarbonyl compounds
|
|
WO2002076941A2
(en)
|
2001-03-27 |
2002-10-03 |
Circagen Pharmaceutical |
Histone deacetylase inhibitors
|
|
US7312247B2
(en)
|
2001-03-27 |
2007-12-25 |
Errant Gene Therapeutics, Llc |
Histone deacetylase inhibitors
|
|
ATE305297T1
(de)
|
2001-04-10 |
2005-10-15 |
Deutsches Krebsforsch |
Verwendung von histonedeacetylasehemmern zur behandlung von papillomaviren assoziierte krankheiten
|
|
AR035455A1
(es)
|
2001-04-23 |
2004-05-26 |
Hoffmann La Roche |
Derivados triciclicos de alquilhidroxamato , procesos para su elaboracion, composiciones farmaceuticas que los contienen, y el uso de dichos compuestos en la preparacion de medicamentos
|
|
US6905669B2
(en)
|
2001-04-24 |
2005-06-14 |
Supergen, Inc. |
Compositions and methods for reestablishing gene transcription through inhibition of DNA methylation and histone deacetylase
|
|
EP1390491B1
(en)
|
2001-05-02 |
2008-07-16 |
The Regents of the University of California |
Method for treating neurodegenerative, psychiatric and other disorders with deacetylase inhibitors
|
|
US20030187027A1
(en)
|
2001-05-09 |
2003-10-02 |
Schreiber Stuart L. |
Dioxanes and uses thereof
|
|
US7244853B2
(en)
*
|
2001-05-09 |
2007-07-17 |
President And Fellows Of Harvard College |
Dioxanes and uses thereof
|
|
US7063973B2
(en)
*
|
2001-06-14 |
2006-06-20 |
Sloan-Kettering Institute For Cancer Research |
HDAC9 polypeptides and polynucleotides and uses thereof
|
|
EP1532244A4
(en)
|
2001-06-14 |
2005-12-14 |
Bristol Myers Squibb Co |
NEW HISTONIC HUMAN DEACETYLASES
|
|
WO2002102981A2
(en)
|
2001-06-15 |
2002-12-27 |
The Trustees Of Columbia University In The City Of New York |
SIR2α-BASED THERAPEUTIC AND PROPHYLACTIC METHODS
|
|
US6784173B2
(en)
|
2001-06-15 |
2004-08-31 |
Hoffmann-La Roche Inc. |
Aromatic dicarboxylic acid derivatives
|
|
US7488587B2
(en)
|
2001-06-19 |
2009-02-10 |
The J. David Gladstone Institutes |
Histone deacetylase and methods of use thereof
|
|
WO2003000715A1
(en)
|
2001-06-22 |
2003-01-03 |
Ceres, Inc. |
Chimeric histone acetyltransferase polypeptides
|
|
EP1411975A4
(en)
|
2001-07-03 |
2005-04-27 |
Univ Virginia |
METHYLATION OF HISTON H4 AT ARGININE 3
|
|
WO2003014340A2
(en)
|
2001-08-03 |
2003-02-20 |
Novartis Ag |
Human histone deacetylase-related gene and protein hdac10
|
|
US20040266718A1
(en)
|
2001-08-06 |
2004-12-30 |
Zuomei Li |
Inhibition of specific histone deacetylase isoforms
|
|
ITMI20011733A1
(it)
|
2001-08-07 |
2003-02-07 |
Italfarmaco Spa |
Derivati dell'acido idrossamico inibitori degli enzimi istone deacetilasi, quali nuovi farmaci antiinfiammatori inibenti la sintesi di citoc
|
|
AR034897A1
(es)
*
|
2001-08-07 |
2004-03-24 |
Hoffmann La Roche |
Derivados n-monoacilados de o-fenilendiaminas, sus analogos heterociclicos de seis miembros y su uso como agentes farmaceuticos
|
|
RU2298414C2
(ru)
|
2001-08-21 |
2007-05-10 |
Астеллас Фарма Инк. |
Медицинское применение ингибитора гистоновой дезацетилазы и способ оценки его противоопухолевого действия
|
|
US20040259772A1
(en)
|
2001-08-24 |
2004-12-23 |
Antonio Fojo |
Use of a histone deacetylase inhibitor to increase the entry of an adenoviral agent into a cell
|
|
EP1291015A1
(en)
|
2001-09-10 |
2003-03-12 |
Lunamed AG |
Dosage forms having prolonged active ingredient release
|
|
US7868204B2
(en)
|
2001-09-14 |
2011-01-11 |
Methylgene Inc. |
Inhibitors of histone deacetylase
|
|
US6897220B2
(en)
|
2001-09-14 |
2005-05-24 |
Methylgene, Inc. |
Inhibitors of histone deacetylase
|
|
MXPA04002397A
(es)
|
2001-09-14 |
2004-12-02 |
Methylgene Inc |
Inhibidores de histona deacetilasa.
|
|
EP1293205A1
(en)
|
2001-09-18 |
2003-03-19 |
G2M Cancer Drugs AG |
Valproic acid and derivatives thereof for the combination therapy of human cancers, for the treatment of tumour metastasis and minimal residual disease
|
|
DE10148618B4
(de)
|
2001-09-25 |
2007-05-03 |
Schering Ag |
Substituierte N-(1,4,5,6-Tetrahydro-cyclopentapyrazol-3-yl)-Derivate, deren Herstellung und Verwendung als Arzneimittel
|
|
US6706686B2
(en)
*
|
2001-09-27 |
2004-03-16 |
The Regents Of The University Of Colorado |
Inhibition of histone deacetylase as a treatment for cardiac hypertrophy
|
|
GB0123664D0
(en)
|
2001-10-02 |
2001-11-21 |
Inst Of Cancer Res The |
Histone deacetylase 9
|
|
EP2269609A3
(en)
|
2001-10-16 |
2012-07-11 |
Sloan-Kettering Institute for Cancer Research |
Treatment of neurodegenerative diseases and cancer of the brain with SAHA
|
|
AU2002348474A1
(en)
|
2001-10-18 |
2003-04-28 |
The Salk Institute For Biological Studies |
Methods of using deacetylase inhibitors to promote cell differentiation and regeneration
|
|
CN100457183C
(zh)
|
2001-11-06 |
2009-02-04 |
诺瓦提斯公司 |
环氧酶-2抑制剂/组蛋白脱乙酰酶抑制剂的组合
|
|
JP2005528331A
(ja)
|
2001-11-21 |
2005-09-22 |
イェシバ・ユニバーシティ |
Sir2産物および活性
|
|
US7514406B2
(en)
*
|
2001-11-27 |
2009-04-07 |
Fred Hutchinson Cancer Research Center |
Methods for inhibiting deacetylase activity
|
|
WO2003048774A1
(en)
|
2001-12-07 |
2003-06-12 |
Novartis Ag |
Use of alpha-tubulin acetylation levels as a biomarker for protein deacetylase inhibitors
|
|
WO2003053468A1
(en)
|
2001-12-21 |
2003-07-03 |
Universite Libre De Bruxelles |
Method for obtaining the elimination of integrated and functional viruses from infected mammal cells
|
|
WO2003057722A2
(en)
|
2001-12-28 |
2003-07-17 |
Fujisawa Pharmaceutical Co., Ltd. |
Cyclic tetrapeptide compound and use thereof
|
|
ITRM20020016A1
(it)
|
2002-01-15 |
2003-07-15 |
Sigma Tau Ind Farmaceuti |
Derivati di acidi fenil(alchil)carbossilici e derivati fenilalchileterociclici dionici, loro uso come medicamenti ad attivita' ipoglicemizza
|
|
WO2003064698A1
(en)
|
2002-01-25 |
2003-08-07 |
Board Of Regents, The University Of Texas System |
Electrophoretic assay to predict risk of cancer and the efficacy and toxicity of cancer therapy
|
|
TWI329105B
(en)
|
2002-02-01 |
2010-08-21 |
Rigel Pharmaceuticals Inc |
2,4-pyrimidinediamine compounds and their uses
|
|
US20040091951A1
(en)
*
|
2002-02-07 |
2004-05-13 |
Axys Pharmaceuticals, Inc. |
Assay for measuring acetylation or deacetylation activity of an enzyme
|
|
JP2006505241A
(ja)
|
2002-02-08 |
2006-02-16 |
ノバルティス アクチエンゲゼルシャフト |
Hdac阻害活性を有する化合物のスクリーニング法
|
|
US20030155067A1
(en)
|
2002-02-15 |
2003-08-21 |
John Syron |
Method and article for masking portions of a vehicle by adherent appliques
|
|
WO2003070188A2
(en)
|
2002-02-15 |
2003-08-28 |
Sloan-Kettering Institute For Cancer Research |
Method of treating trx mediated diseases
|
|
CN1646558B
(zh)
|
2002-02-20 |
2010-05-12 |
国立大学法人九州工业大学 |
组蛋白脱乙酰酶抑制剂
|
|
US7456219B2
(en)
|
2002-03-04 |
2008-11-25 |
Merck Hdac Research, Llc |
Polymorphs of suberoylanilide hydroxamic acid
|
|
MXPA04008577A
(es)
|
2002-03-04 |
2005-07-13 |
Aton Pharma Inc |
Metodos para inducir diferenciacion terminal.
|
|
US7148257B2
(en)
*
|
2002-03-04 |
2006-12-12 |
Merck Hdac Research, Llc |
Methods of treating mesothelioma with suberoylanilide hydroxamic acid
|
|
US20040132825A1
(en)
|
2002-03-04 |
2004-07-08 |
Bacopoulos Nicholas G. |
Methods of treating cancer with HDAC inhibitors
|
|
EP1578924A4
(en)
*
|
2002-03-07 |
2008-08-13 |
Univ Johns Hopkins |
GENOMIC SCREEN ON EPIGENETIC MUTED TUMORSUPPRESSORGENE
|
|
CN1650033A
(zh)
|
2002-03-07 |
2005-08-03 |
约翰霍普金斯大学医学院 |
针对与癌症相关的表观遗传学沉默基因的基因组筛选
|
|
KR20040094672A
(ko)
|
2002-03-13 |
2004-11-10 |
얀센 파마슈티카 엔.브이. |
히스톤 디아세틸라제의 신규한 저해제로서의설포닐아미노-유도체
|
|
ES2347544T3
(es)
|
2002-03-13 |
2010-11-02 |
Janssen Pharmaceutica Nv |
Inhibidores de histona-desacetilasas.
|
|
AU2003218738B2
(en)
|
2002-03-13 |
2009-01-08 |
Janssen Pharmaceutica N.V. |
Sulfonyl-derivatives as novel inhibitors of histone deacetylase
|
|
EP1485348B1
(en)
|
2002-03-13 |
2008-06-11 |
Janssen Pharmaceutica N.V. |
Carbonylamino-derivatives as novel inhibitors of histone deacetylase
|
|
OA12788A
(en)
|
2002-03-13 |
2006-07-10 |
Janssen Pharmaceutica Nv |
Piperazinyl-, piperidinyl- and morpholinyl-derivatives as novel inhibitors of histone deacetylase.
|
|
US20050009030A1
(en)
*
|
2002-03-26 |
2005-01-13 |
Fabien Schweighoffer |
Histone deacetylase: novel molecular target of neurotoxicity
|
|
US20040077591A1
(en)
*
|
2002-03-28 |
2004-04-22 |
The Brigham And Women's Hospital, Inc. |
Histone deacetylase inhibitors for the treatment of multiple sclerosis, amyotrophic lateral sclerosis and Alzheimer's Disease
|
|
US6841565B1
(en)
*
|
2002-03-29 |
2005-01-11 |
The Ohio State University |
Treatment of patients with chronic lymphocytic leukemia
|
|
JP4606027B2
(ja)
|
2002-04-03 |
2011-01-05 |
トポターゲット ユーケー リミテッド |
Hdac阻害剤としてのピペラジン結合を有するカルバミン酸化合物
|
|
JP2005521737A
(ja)
|
2002-04-05 |
2005-07-21 |
藤沢薬品工業株式会社 |
腎臓癌の治療のためのデプシペプチド
|
|
TWI319387B
(en)
|
2002-04-05 |
2010-01-11 |
Astrazeneca Ab |
Benzamide derivatives
|
|
US7495022B2
(en)
|
2002-04-11 |
2009-02-24 |
Sk Chemicals Co., Ltd. |
α,β-unsaturated hydroxamic acid derivatives and their use as histone deacetylase inhibitors
|
|
MY134200A
(en)
|
2002-04-12 |
2007-11-30 |
Kowa Co |
Method for treating cancer
|
|
AU2003226408B2
(en)
|
2002-04-15 |
2007-06-14 |
Sloan-Kettering Institute For Cancer Research |
Combination therapy for the treatment of cancer
|
|
US6620838B1
(en)
|
2002-04-19 |
2003-09-16 |
Signal Pharmaceuticals, Inc. |
Benzopyrazone compounds, compositions thereof, and methods of treatment therewith
|
|
US20030206946A1
(en)
|
2002-04-26 |
2003-11-06 |
Yih-Lin Chung |
Methods for therapy of connective tissue disease
|
|
US6809118B2
(en)
|
2002-07-25 |
2004-10-26 |
Yih-Lin Chung |
Methods for therapy of radiation cutaneous syndrome
|
|
GB0209715D0
(en)
*
|
2002-04-27 |
2002-06-05 |
Astrazeneca Ab |
Chemical compounds
|
|
US20040018522A1
(en)
*
|
2002-05-09 |
2004-01-29 |
Brigham And Women's Hospital, Inc. |
Identification of dysregulated genes in patients with multiple sclerosis
|
|
EP1362914A3
(en)
|
2002-05-15 |
2004-05-06 |
Schering AG |
Histone deacetylase inhibitor and use thereof
|
|
US7351542B2
(en)
*
|
2002-05-20 |
2008-04-01 |
The Regents Of The University Of California |
Methods of modulating tubulin deacetylase activity
|
|
CA2486385C
(en)
*
|
2002-05-22 |
2013-12-10 |
Errant Gene Therapeutics, Llc |
Histone deacetylase inhibitors based on trihalomethylcarbonyl compounds
|
|
CA2486303C
(en)
|
2002-05-22 |
2013-04-30 |
Errant Gene Therapeutics, Llc |
Histone deacetylase inhibitors based on alpha-ketoepoxide compounds
|
|
US20030224473A1
(en)
|
2002-05-23 |
2003-12-04 |
Mccafferty Dewey G. |
Methods for screening for histone deacetylase activity and for identifying histone deacetylase inhibitors
|
|
DK1506313T3
(da)
|
2002-05-23 |
2011-04-18 |
Univ California |
Fremgangsmåder til screening af modulatorer af den mitokondrielle NAD-afhængige deacetylase SIRT3
|
|
US20040002447A1
(en)
*
|
2002-06-04 |
2004-01-01 |
Regents Of The University Of California |
Induction of insulin expression
|
|
BR0311714A
(pt)
|
2002-06-10 |
2005-03-01 |
Novartis Ag |
Combinações que compreendem epotilonas e seus usos farmacêuticos
|
|
JP2005529625A
(ja)
|
2002-06-19 |
2005-10-06 |
オンコセラピー・サイエンス株式会社 |
結腸直腸腫瘍の診断のための方法
|
|
US20050084967A1
(en)
*
|
2002-06-28 |
2005-04-21 |
Xcyte Therapies, Inc. |
Compositions and methods for eliminating undesired subpopulations of T cells in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation
|
|
WO2004002940A1
(en)
|
2002-07-01 |
2004-01-08 |
Pharmacia & Upjohn Company |
Inhibitors of hcv ns5b polymerase
|
|
US20040072770A1
(en)
|
2002-07-03 |
2004-04-15 |
Besterman Jeffrey M. |
Methods for specifically inhibiting histone deacetylase-7 and 8
|
|
SE0202157D0
(sv)
*
|
2002-07-09 |
2002-07-09 |
Biovitrum Ab |
Methods for identification of compounds modulating insulin resistance
|
|
GB0215844D0
(en)
|
2002-07-09 |
2002-08-14 |
Novartis Ag |
Organic compounds
|
|
MXPA05000555A
(es)
|
2002-07-17 |
2005-04-28 |
Titan Pharmaceuticals Inc |
Combinacion de farmacos quimioterapeuticos para incrementar la actividad antitumoral.
|
|
AU2003253872A1
(en)
|
2002-07-17 |
2004-02-09 |
Chemgenex Pharmaceuticals, Inc. |
Formulations and methods of administration of cephalotaxines, including homoharringtonine
|
|
US20050176686A1
(en)
|
2002-07-23 |
2005-08-11 |
4Sc Ag |
Novel compounds as histone deacetylase inhibitors
|
|
DE10233412A1
(de)
|
2002-07-23 |
2004-02-12 |
4Sc Ag |
Neue Verbindungen als Histondeacetylase-Inhibitoren
|
|
US20050065596A1
(en)
*
|
2002-07-24 |
2005-03-24 |
Xufan Tseng |
Stents capable of controllably releasing histone deacetylase inhibitors
|
|
KR101083852B1
(ko)
|
2002-07-25 |
2011-11-15 |
소니 주식회사 |
유전자 전사 조절제 및 히스톤 탈아세틸화효소 저해 화합물의 스크리닝 방법
|
|
JP2005539001A
(ja)
|
2002-08-02 |
2005-12-22 |
アージェンタ・ディスカバリー・リミテッド |
ヒストンデアセチラーゼインヒビターとしての置換チエニルヒドロキサム酸
|
|
ES2342378T3
(es)
|
2002-08-20 |
2010-07-06 |
Astellas Pharma Inc. |
Inhibidor de degradacion de matriz extracelular del cartilago artrodial.
|
|
KR20050059158A
(ko)
|
2002-08-30 |
2005-06-17 |
아스텔라스세이야쿠 가부시키가이샤 |
신규 뎁시펩타이드 화합물
|
|
BR0314112A
(pt)
|
2002-09-13 |
2005-07-12 |
Univ Virginia Commonwealth |
Combinação de a) n-{5-[4-(4-metil-piperazino-metil)-benzoilamido]-2-metil fenil}-4-(3-piridil)-2-pirimidina-amina e b) um inibidor de desacetilase de histona para o tratamento de leucemia
|
|
EP1400806A1
(en)
|
2002-09-18 |
2004-03-24 |
G2M Cancer Drugs AG |
The use of molecular markers for the preclinical and clinical profiling of inhibitors of enzymes having histone deacetylase activity
|
|
US20040127571A1
(en)
|
2002-09-19 |
2004-07-01 |
University Of South Florida |
Method of Treating Leukemia with a Combination of Suberoylanilide Hydromaxic Acid and Imatinib Mesylate
|
|
EP1403639A1
(en)
|
2002-09-30 |
2004-03-31 |
G2M Cancer Drugs AG |
Antibody tools for the diagnostic use in the medical therapy with inhibitors of histone deacetylases
|
|
JP2006503082A
(ja)
|
2002-10-17 |
2006-01-26 |
メシルジーン、インコーポレイテッド |
ヒストンデアセチラーゼの阻害剤
|
|
US20040077083A1
(en)
*
|
2002-10-17 |
2004-04-22 |
Isis Pharmaceuticals Inc. |
Antisense modulation of histone deacetylase 4 expression
|
|
US20040077084A1
(en)
*
|
2002-10-17 |
2004-04-22 |
Isis Pharmaceuticals Inc. |
Antisense modulation of histone deacetylase 4 expression
|
|
CA2504460A1
(en)
|
2002-11-12 |
2004-05-27 |
Peter G. Klimko |
Histone deacetylase inhibitors for the treatment of ocular neovascular or edematous disorders and diseases
|
|
MXPA05004738A
(es)
|
2002-11-12 |
2005-08-03 |
Alcon Inc |
Inhibidores de histona deacetilasa para tratar enfermedades degenerativas del ojo.
|
|
WO2004046312A2
(en)
|
2002-11-15 |
2004-06-03 |
The Board Of Trustees Of The University Of Illinois |
Methods for in vitro expansion of hematopoietic stem cells
|
|
GB0226855D0
(en)
|
2002-11-18 |
2002-12-24 |
Queen Mary & Westfield College |
Histone deacetylase inhibitors
|
|
EP1567142A4
(en)
|
2002-11-20 |
2005-12-14 |
Errant Gene Therapeutics Llc |
TREATMENT OF PULMONARY CELLS WITH HISTONE DEACETYLASE INHIBITORS
|
|
WO2004052292A2
(en)
|
2002-12-06 |
2004-06-24 |
University Of South Florida |
Histone deacetylase inhibitor enhancement of trail-induced apoptosis
|
|
TW200426138A
(en)
|
2002-12-10 |
2004-12-01 |
Hoffmann La Roche |
Novel arylene-carboxylic acid (2-amino-phenyl)-amide derivatives, their manufacture and use as pharmaceutical agents
|
|
WO2004053140A2
(en)
|
2002-12-12 |
2004-06-24 |
Jawaharlal Nehru Centre For Advanced Scientific Research |
Modulators (inhibitors/activators) of histone acetyltransferases
|
|
TW200418825A
(en)
|
2002-12-16 |
2004-10-01 |
Hoffmann La Roche |
Novel (R)-and (S) enantiomers of thiophene hydroxamic acid derivatives
|
|
ITMI20022745A1
(it)
|
2002-12-23 |
2004-06-24 |
Coimex Scrl United Companies |
Esteri misti dell'acido ialuronico ad attivita' citostatica e prodifferenziante e procedimento per la loro produzione.
|
|
JP2006514991A
(ja)
*
|
2002-12-27 |
2006-05-18 |
シエーリング アクチエンゲゼルシャフト |
新規医薬組合せ
|
|
US20040197888A1
(en)
|
2002-12-31 |
2004-10-07 |
Armour Christopher D. |
Alternatively spliced isoforms of histone deacetylase 3 (HDAC3)
|
|
ITMI20030025A1
(it)
|
2003-01-10 |
2004-07-11 |
Italfarmaco Spa |
Derivati dell'acido idrossammico ad attivita' antinfiammatoria.
|
|
US7135493B2
(en)
|
2003-01-13 |
2006-11-14 |
Astellas Pharma Inc. |
HDAC inhibitor
|
|
US20050222013A1
(en)
|
2003-01-16 |
2005-10-06 |
Georgetown University |
Methods for the use of inhibitors of histone deacetylase as synergistic agents in cancer therapy
|
|
AU2004205372B2
(en)
|
2003-01-17 |
2011-02-24 |
Topotarget Uk Limited |
Hydroxamic acid compounds comprising an ester or ketone linkage as HDAC inhibitors
|
|
WO2004067480A2
(en)
|
2003-01-25 |
2004-08-12 |
Oxford Glycosciences (Uk) Ltd |
Substituted phenylurea derivatives as hdac inhibitors
|
|
EP1590336B1
(en)
|
2003-01-27 |
2010-12-01 |
Merck Sharp & Dohme Corp. |
Substituted pyrazoles, compositions containing such compounds and methods of use
|
|
TW200424174A
(en)
|
2003-02-06 |
2004-11-16 |
Hoffmann La Roche |
New TP diamide
|
|
US7208491B2
(en)
|
2003-02-07 |
2007-04-24 |
Hoffmann-La Roche Inc. |
N-monoacylated o-phenylenediamines
|
|
AU2003900608A0
(en)
|
2003-02-11 |
2003-02-27 |
Fujisawa Pharmaceutical Co., Ltd. |
Hdac inhibitor
|
|
EP1592811A2
(en)
|
2003-02-11 |
2005-11-09 |
Wyeth |
Methods for monitoring drug activities in vivo
|
|
AU2003900587A0
(en)
|
2003-02-11 |
2003-02-27 |
Fujisawa Pharmaceutical Co., Ltd. |
Hdac inhibitor
|
|
WO2004071464A2
(en)
|
2003-02-12 |
2004-08-26 |
Johns Hopkins University School Of Medicine |
Diagnostic application of differentially-expressed genes in lympho-hematopoietic stem cells
|
|
US20040241856A1
(en)
|
2003-02-12 |
2004-12-02 |
Irm Llc, A Delaware Limited Liability Company |
Methods and compositions for modulating stem cells
|
|
US7244751B2
(en)
|
2003-02-14 |
2007-07-17 |
Shenzhen Chipscreen Biosciences Ltd. |
Histone deacetylase inhibitors of novel benzamide derivatives with potent differentiation and anti-proliferation activity
|
|
CA2519320A1
(en)
|
2003-02-19 |
2004-09-02 |
Astellas Pharma Inc. |
Method of estimating antitumor effect of histone deacetylase inhibitor
|
|
AU2004215624B2
(en)
|
2003-02-25 |
2011-06-02 |
Topotarget Uk Limited |
Hydroxamic acid compounds comprising a bicyclic heteroaryl group as HDAC inhibitors
|
|
US7381825B2
(en)
|
2003-03-17 |
2008-06-03 |
Takeda San Diego, Inc. |
Histone deacetylase inhibitors
|
|
CA2520611A1
(en)
|
2003-04-01 |
2004-10-21 |
Memorial Sloan-Kettering Cancer Center |
Hydroxamic acid compounds and methods of use thereof
|
|
TW200424187A
(en)
|
2003-04-04 |
2004-11-16 |
Hoffmann La Roche |
New oxime derivatives and their use as pharmaceutically active agents
|
|
ES2328819T3
(es)
|
2003-04-07 |
2009-11-18 |
Pharmacyclics, Inc. |
Hidroxamatos como agentes terapeuticos.
|
|
US7226930B2
(en)
|
2003-04-18 |
2007-06-05 |
Memory Pharmaceutical Corporation |
Phosphodiesterase 4 inhibitors
|
|
US20040213826A1
(en)
|
2003-04-28 |
2004-10-28 |
Marx Steven O. |
Medical devices and methods for inhibiting proliferation of smooth muscle cells
|
|
US20050112128A1
(en)
|
2003-05-21 |
2005-05-26 |
Myogen, Inc. And Board Of Regents, The University Of Texas System |
Inhibition of protein kinase c-mu (PKD) as a treatment for cardiac hypertrophy and heart failure
|
|
AU2004241729A1
(en)
|
2003-05-21 |
2004-12-02 |
Novartis Ag |
Combination of histone deacetylase inhibitors with chemotherapeutic agents
|
|
PE20050206A1
(es)
|
2003-05-26 |
2005-03-26 |
Schering Ag |
Composicion farmaceutica que contiene un inhibidor de histona deacetilasa
|
|
US20050020557A1
(en)
*
|
2003-05-30 |
2005-01-27 |
Kosan Biosciences, Inc. |
Method for treating diseases using HSP90-inhibiting agents in combination with enzyme inhibitors
|
|
CN1798733A
(zh)
|
2003-06-10 |
2006-07-05 |
凯利普西斯公司 |
作为组蛋白脱乙酰基酶抑制剂的疾病治疗用羰基化合物
|
|
US7271195B2
(en)
*
|
2003-06-10 |
2007-09-18 |
Kalypsys, Inc. |
Carbonyl compounds as inhibitors of histone deacetylase for the treatment of disease
|
|
US20060235012A1
(en)
|
2003-06-16 |
2006-10-19 |
Chroma Therapeutics Limited |
Carboline and betacarboline derivatives for use as hdac enzyme inhibitors
|
|
EP1491188A1
(en)
|
2003-06-25 |
2004-12-29 |
G2M Cancer Drugs AG |
Topical use of valproic acid for the prevention or treatment of skin disorders
|
|
JP4661782B2
(ja)
|
2003-06-27 |
2011-03-30 |
アステラス製薬株式会社 |
軟部肉腫治療剤
|
|
JP2007530417A
(ja)
|
2003-07-01 |
2007-11-01 |
プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ |
細胞及び生物の寿命及びストレス応答を操作するための組成物
|
|
CA2531253A1
(en)
|
2003-07-02 |
2005-02-24 |
Vern L. Schramm |
Sir2 regulation
|
|
CA2531661C
(en)
|
2003-07-07 |
2013-03-12 |
Georgetown University |
Histone deacetylase inhibitors and methods of use thereof
|
|
US7842835B2
(en)
|
2003-07-07 |
2010-11-30 |
Georgetown University |
Histone deacetylase inhibitors and methods of use thereof
|
|
WO2005004861A1
(en)
|
2003-07-15 |
2005-01-20 |
Korea Research Institute Of Bioscience And Biotechnology |
A use of novel 2-oxo-heterocyclic compounds and the pharmaceutical compositions comprising the same
|
|
GB0316889D0
(en)
|
2003-07-18 |
2003-08-20 |
Univ London |
Pharmaceutical agents
|
|
US20050037992A1
(en)
|
2003-07-22 |
2005-02-17 |
John Lyons |
Composition and method for treating neurological disorders
|
|
WO2005011598A2
(en)
|
2003-07-31 |
2005-02-10 |
University Of South Florida |
Leukemia treatment method and composition
|
|
WO2005014588A1
(en)
|
2003-08-01 |
2005-02-17 |
Argenta Discovery Limited |
Substituted thienyl-hydroxamic acids having histone deacetylase activity
|
|
US20050032794A1
(en)
*
|
2003-08-05 |
2005-02-10 |
Padia Janak K. |
Diamine derivatives of quinone and uses thereof
|
|
JP2007501775A
(ja)
|
2003-08-07 |
2007-02-01 |
ノバルティス アクチエンゲゼルシャフト |
免疫抑制剤としてのヒストンデアセチラーゼ阻害剤
|
|
EP1653973A1
(en)
|
2003-08-08 |
2006-05-10 |
Novartis AG |
Combinations comprising staurosporines
|
|
MXPA05011286A
(es)
|
2003-08-20 |
2006-01-24 |
Axys Pharm Inc |
Derivados de acetileno como inhibidores de histona deacetilasa.
|
|
PL379887A1
(pl)
|
2003-08-26 |
2006-11-27 |
Merck Hdac Research, Llc |
Sposób leczenia raka inhibitorami HDAC
|
|
JP2007504131A
(ja)
|
2003-08-29 |
2007-03-01 |
エートン ファーマ インコーポレーティッド |
癌の組み合わせ処置法
|
|
US20050059682A1
(en)
*
|
2003-09-12 |
2005-03-17 |
Supergen, Inc., A Delaware Corporation |
Compositions and methods for treatment of cancer
|
|
WO2005028620A2
(en)
|
2003-09-16 |
2005-03-31 |
The Rockefeller University |
Histone modifications as binary switches controlling gene expression
|
|
CN103788089A
(zh)
|
2003-09-17 |
2014-05-14 |
詹森药业有限公司 |
作为血清素受体调节剂的稠合杂环化合物
|
|
CN1852737A
(zh)
|
2003-09-18 |
2006-10-25 |
诺瓦提斯公司 |
组蛋白脱乙酰酶抑制剂与死亡受体配体的组合
|
|
AR046411A1
(es)
|
2003-09-22 |
2005-12-07 |
S Bio Pte Ltd |
Derivados de bencimidazol. aplicaciones farmaceuticas
|
|
CA2539117A1
(en)
|
2003-09-24 |
2005-04-07 |
Methylgene Inc. |
Inhibitors of histone deacetylase
|
|
ES2344899T3
(es)
*
|
2003-09-25 |
2010-09-09 |
Astellas Pharma Inc. |
Agente antitumoral que comprende un inhibidor de histona desacetilasa y un inhibidor de topoisomerasa ii.
|
|
CA2542096A1
(en)
|
2003-10-09 |
2005-04-21 |
Aton Pharma, Inc. |
Thiophene and benzothiophene hydroxamic acid derivatives
|
|
US20050124625A1
(en)
|
2003-10-21 |
2005-06-09 |
Salvati Mark E. |
Piperazine derivatives and their use as modulators of nuclear hormone receptor function
|
|
AU2004284030A1
(en)
|
2003-10-27 |
2005-05-06 |
S*Bio Pte Ltd |
Acylurea connected and sulfonylurea connected hydroxamates
|
|
US20070167499A1
(en)
|
2003-10-27 |
2007-07-19 |
A*Bio Pte Ltd. |
Biaryl linked hydroxamates: preparation and pharmaceutical applications
|
|
IN2003CH00929A
(OSRAM)
|
2003-11-13 |
2008-10-06 |
|
|
|
JP2007512367A
(ja)
|
2003-11-26 |
2007-05-17 |
エートン ファーマ インコーポレーティッド |
ジアミンおよびイミノ二酢酸ヒドロキサム酸誘導体
|
|
WO2005053609A2
(en)
|
2003-11-26 |
2005-06-16 |
Guilford Pharmaceuticals Inc. |
Methods of nad+-dependent deacetylase inhibitors
|
|
US20080004290A1
(en)
|
2003-11-28 |
2008-01-03 |
The University Of Queensland |
Anti-Cancer Agents
|
|
WO2005055928A2
(en)
|
2003-12-02 |
2005-06-23 |
The Ohio State University Research Foundation |
Zn2+ -chelating motif-tethered short -chain fatty acids as a novel class of histone deacetylase inhibitors
|
|
EP1713460A2
(en)
|
2003-12-10 |
2006-10-25 |
Wisconsin Alumni Research Foundation |
Fk228 analogs and their use as hdac-inhibitors
|
|
EP1541549A1
(en)
|
2003-12-12 |
2005-06-15 |
Exonhit Therapeutics S.A. |
Tricyclic hydroxamate and benzaminde derivatives, compositions and methods
|
|
US20050137234A1
(en)
|
2003-12-19 |
2005-06-23 |
Syrrx, Inc. |
Histone deacetylase inhibitors
|
|
US8652502B2
(en)
|
2003-12-19 |
2014-02-18 |
Cordis Corporation |
Local vascular delivery of trichostatin A alone or in combination with sirolimus to prevent restenosis following vascular injury
|
|
US20050159470A1
(en)
|
2003-12-19 |
2005-07-21 |
Syrrx, Inc. |
Histone deacetylase inhibitors
|
|
CN101247793B
(zh)
|
2003-12-29 |
2013-04-10 |
哈佛大学校长及研究员协会 |
治疗或预防肥胖和胰岛素抗性病症的组合物
|
|
CA2553468A1
(en)
|
2004-01-21 |
2005-08-04 |
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti Spa |
Inhibitors of mammalian hdac 11 useful for treating hdac 11 mediated disorders
|
|
KR101258504B1
(ko)
|
2004-03-26 |
2013-04-26 |
메틸진 인코포레이티드 |
히스톤 데아세틸라제의 억제제
|
|
WO2006066133A2
(en)
|
2004-12-16 |
2006-06-22 |
Takeda San Diego, Inc. |
Histone deacetylase inhibitors
|
|
EP1896436A2
(en)
|
2005-05-11 |
2008-03-12 |
Takeda San Diego, Inc. |
Histone deacetylase inhibitors
|
|
ZA200800901B
(en)
|
2005-07-14 |
2010-05-26 |
Takeda San Diego Inc |
Histone deacetylase inhibitors
|