ATE320484T1 - Histone-deacetylase-8 proteine, nukleinsäuren und methoden zur verwendung - Google Patents

Histone-deacetylase-8 proteine, nukleinsäuren und methoden zur verwendung

Info

Publication number
ATE320484T1
ATE320484T1 AT00982576T AT00982576T ATE320484T1 AT E320484 T1 ATE320484 T1 AT E320484T1 AT 00982576 T AT00982576 T AT 00982576T AT 00982576 T AT00982576 T AT 00982576T AT E320484 T1 ATE320484 T1 AT E320484T1
Authority
AT
Austria
Prior art keywords
present
methods
polypeptides
nucleic acids
proteins
Prior art date
Application number
AT00982576T
Other languages
English (en)
Inventor
Joseph Buggy
Original Assignee
Axys Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Axys Pharm Inc filed Critical Axys Pharm Inc
Application granted granted Critical
Publication of ATE320484T1 publication Critical patent/ATE320484T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Seasonings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT00982576T 1999-12-08 2000-12-08 Histone-deacetylase-8 proteine, nukleinsäuren und methoden zur verwendung ATE320484T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16972399P 1999-12-08 1999-12-08

Publications (1)

Publication Number Publication Date
ATE320484T1 true ATE320484T1 (de) 2006-04-15

Family

ID=22616924

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00982576T ATE320484T1 (de) 1999-12-08 2000-12-08 Histone-deacetylase-8 proteine, nukleinsäuren und methoden zur verwendung

Country Status (8)

Country Link
EP (1) EP1246905B1 (de)
JP (2) JP2003516144A (de)
AT (1) ATE320484T1 (de)
AU (1) AU1959001A (de)
CA (1) CA2393725A1 (de)
DE (1) DE60026733T2 (de)
ES (1) ES2260080T3 (de)
WO (1) WO2001042437A2 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2260080T3 (es) * 1999-12-08 2006-11-01 Axys Pharmaceuticals, Inc. Proteinas histono deacetilasa-8, acidos nucleicos y procedimiento de utilizacion.
PE20020354A1 (es) 2000-09-01 2002-06-12 Novartis Ag Compuestos de hidroxamato como inhibidores de histona-desacetilasa (hda)
JP2004532647A (ja) 2001-06-14 2004-10-28 スローン−ケターリング インスティチュート フォー キャンサー リサーチ Ｈｄａｃ９ポリペプチドおよびポリヌクレオチドならびにその使用
EP1407049A4 (de) 2001-06-19 2005-03-23 David Gladstone Inst Histon-deacetylase und verfahren zur verwendung davon
US6706686B2 (en) 2001-09-27 2004-03-16 The Regents Of The University Of Colorado Inhibition of histone deacetylase as a treatment for cardiac hypertrophy
GB0123664D0 (en) 2001-10-02 2001-11-21 Inst Of Cancer Res The Histone deacetylase 9
WO2003032921A2 (en) 2001-10-16 2003-04-24 Sloan-Kettering Institute For Cancer Research Treatment of neurodegenerative diseases and cancer of the brain
GB0226855D0 (en) 2002-11-18 2002-12-24 Queen Mary & Westfield College Histone deacetylase inhibitors
US20060051815A1 (en) 2004-06-25 2006-03-09 The J. David Gladstone Institutes Methods of treating smooth muscle cell disorders
CN101263121A (zh) 2005-07-14 2008-09-10 塔克达圣地亚哥公司 组蛋白脱乙酰基酶抑制剂
GB0620823D0 (en) 2006-10-19 2006-11-29 Univ London Histone deacetylase inhibitors
CN105979941A (zh) * 2013-08-20 2016-09-28 希望之城 用于治疗癌症的hdac8抑制剂
WO2015051035A1 (en) 2013-10-01 2015-04-09 The J. David Gladstone Institutes Compositions, systems and methods for gene expression noise drug screening and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1105143A4 (de) * 1998-08-21 2002-07-17 Smithkline Beecham Corp Menschliches histon-deacetylase-gen hd4
ES2260080T3 (es) * 1999-12-08 2006-11-01 Axys Pharmaceuticals, Inc. Proteinas histono deacetilasa-8, acidos nucleicos y procedimiento de utilizacion.

Also Published As

Publication number Publication date
EP1246905B1 (de) 2006-03-15
ES2260080T3 (es) 2006-11-01
EP1246905A2 (de) 2002-10-09
AU1959001A (en) 2001-06-18
JP2003516144A (ja) 2003-05-13
CA2393725A1 (en) 2001-06-14
JP2011182800A (ja) 2011-09-22
DE60026733T2 (de) 2006-11-02
WO2001042437A3 (en) 2002-01-10
DE60026733D1 (de) 2006-05-11
WO2001042437A2 (en) 2001-06-14

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Legal Events

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