|
WO2000021996A2
(en)
*
|
1998-10-13 |
2000-04-20 |
Genentech, Inc. |
Methods and compositions for inhibiting neoplastic cell growth
|
|
WO2001004311A1
(en)
*
|
1999-07-07 |
2001-01-18 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
WO2001019991A1
(en)
*
|
1999-09-15 |
2001-03-22 |
Genentech, Inc. |
Compositions and methods for the treatment of immune related diseases
|
|
US5728546A
(en)
|
1995-06-05 |
1998-03-17 |
Human Genome Sciences, Inc. |
Fibroblast growth factor 13
|
|
CA2272239A1
(en)
|
1996-11-27 |
1998-06-04 |
Human Genome Sciences, Inc. |
Fibroblast growth factor-13
|
|
US7026447B2
(en)
|
1997-10-09 |
2006-04-11 |
Human Genome Sciences, Inc. |
53 human secreted proteins
|
|
EP0970209A1
(de)
*
|
1997-03-28 |
2000-01-12 |
Genetics Institute, Inc. |
Sekretierte proteine und polynukleotide die für diese kodieren
|
|
US20020137890A1
(en)
|
1997-03-31 |
2002-09-26 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US7057017B2
(en)
|
1997-04-16 |
2006-06-06 |
Millennium Pharmaceuticals, Inc. |
Human dickkopf-related protein and nucleic acid molecules and uses therefor
|
|
US7169906B2
(en)
|
1997-09-17 |
2007-01-30 |
Genentech, Inc. |
PRO211 polypeptides
|
|
US20030054400A1
(en)
*
|
1997-09-17 |
2003-03-20 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US20020192659A1
(en)
*
|
1997-09-17 |
2002-12-19 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US6974689B1
(en)
|
1997-09-18 |
2005-12-13 |
Genentech, Inc. |
Nucleic acid encoding PRO211 polypeptides
|
|
US20030032102A1
(en)
|
1997-09-18 |
2003-02-13 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US7307152B2
(en)
|
1997-10-17 |
2007-12-11 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
EP1032668B1
(de)
*
|
1997-11-25 |
2008-05-28 |
Genentech, Inc. |
Fibroblasten-wachstumsfaktor-19
|
|
US7446181B2
(en)
|
1998-01-15 |
2008-11-04 |
Millennium Pharmaceuticals, Inc. |
Antibodies that bind human Dickkopf-1 proteins
|
|
US6203979B1
(en)
|
1998-01-16 |
2001-03-20 |
Incyte Pharmaceuticals, Inc. |
Human protease molecules
|
|
US7045333B1
(en)
|
1998-01-16 |
2006-05-16 |
Incyte Corporation |
Human protease molecules
|
|
EP0939124A3
(de)
*
|
1998-02-24 |
2001-03-21 |
Smithkline Beecham Plc |
MBGP1-Sequenzen
|
|
JP2002504377A
(ja)
*
|
1998-02-25 |
2002-02-12 |
スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー |
ヒトシステインプロテアーゼcprot03
|
|
US20020076753A1
(en)
*
|
2000-03-31 |
2002-06-20 |
Glucksmann Maria Alexandra |
31939, a novel human leucine-rich repeat family member and uses thereof
|
|
IL140938A0
(en)
|
1998-08-07 |
2002-02-10 |
Immunex Corp |
Molecules designated b7l-1
|
|
US6168920B1
(en)
*
|
1998-08-10 |
2001-01-02 |
Incyte Genomics, Inc. |
Extracellular adhesive proteins
|
|
IL141426A0
(en)
*
|
1998-09-10 |
2002-03-10 |
Genentech Inc |
Compositions and methods for the treatment of tumor
|
|
KR20010085792A
(ko)
*
|
1998-09-14 |
2001-09-07 |
제넨테크, 인크. |
혈관형성 및 심혈관형성의 촉진 또는 억제
|
|
AU5922999A
(en)
*
|
1998-09-16 |
2000-04-03 |
Genentech Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
CA2343006A1
(en)
*
|
1998-09-17 |
2000-03-23 |
Genentech, Inc. |
Compositions and methods for the treatment of immune related diseases
|
|
US6344541B1
(en)
*
|
1998-09-25 |
2002-02-05 |
Amgen Inc. |
DKR polypeptides
|
|
US7030235B1
(en)
*
|
1998-09-29 |
2006-04-18 |
The Brigham & Women's Hospital, Inc. |
Compositions to detect lesions associated with hearing loss in the cochlear gene, COCH5B2
|
|
JP2002525117A
(ja)
*
|
1998-09-30 |
2002-08-13 |
ミレニアム・フアーマシユーチカルズ・インコーポレーテツド |
Slgpタンパク質及び核酸分子並びにそれらの使用
|
|
US6808895B1
(en)
|
1999-10-06 |
2004-10-26 |
Incyte Corporation |
DNA encoding oxidoreductase and polypeptide encoded thereby
|
|
WO2000020604A2
(en)
*
|
1998-10-06 |
2000-04-13 |
Incyte Pharmaceuticals, Inc. |
Oxidoreductase molecules
|
|
US6902892B1
(en)
|
1998-10-19 |
2005-06-07 |
Diadexus, Inc. |
Method of diagnosing, monitoring, staging, imaging and treating prostate cancer
|
|
WO2000031275A1
(en)
*
|
1998-11-19 |
2000-06-02 |
Azwell Inc. |
Recombinant lysophosphatidic acid phosphatase
|
|
US20050053983A1
(en)
|
1998-11-20 |
2005-03-10 |
Fuso Pharmaceutical Industries, Ltd. |
Novel serine protease BSSP4
|
|
WO2000031277A1
(en)
*
|
1998-11-20 |
2000-06-02 |
Fuso Pharmaceutical Industries, Ltd. |
Novel serine proteases bssp4
|
|
AU2588000A
(en)
*
|
1998-12-02 |
2000-06-19 |
Icos Corporation |
Novel adhesion molecule and methods of use
|
|
EP2075335A3
(de)
*
|
1998-12-22 |
2009-09-30 |
Genentech, Inc. |
Verfahren und Zusammensetzungen zur Hemmung des neoplastischen Zellenwachstums
|
|
AU2375800A
(en)
*
|
1998-12-23 |
2000-07-31 |
Immunex Corporation |
Lectin s3939 dna and polypeptides
|
|
AU2376200A
(en)
*
|
1999-01-07 |
2000-07-24 |
Incyte Pharmaceuticals, Inc. |
Insulin-synthesis genes
|
|
US6174682B1
(en)
|
1999-03-08 |
2001-01-16 |
Millenium Pharmaceuticals, Inc. |
Thioredoxin family active site molecules and uses therefor
|
|
AU1749800A
(en)
*
|
1999-03-12 |
2000-10-04 |
Genentech Inc. |
Methods and compositions for inhibiting neoplastic cell growth
|
|
US6436642B1
(en)
|
1999-04-20 |
2002-08-20 |
Curagen Corporation |
Method of classifying a thyroid carcinoma using differential gene expression
|
|
US6485957B1
(en)
*
|
1999-04-30 |
2002-11-26 |
Ortho-Mcneil Pharmaceutical, Inc. |
DNA encoding the human serine protease EOS
|
|
US7034132B2
(en)
|
2001-06-04 |
2006-04-25 |
Anderson David W |
Therapeutic polypeptides, nucleic acids encoding same, and methods of use
|
|
EP1978029A3
(de)
*
|
1999-06-15 |
2008-10-15 |
Genentech, Inc. |
Sekretierte und Transmembran-Polypeptide sowie Nukleinsäuren zu deren Kodierung
|
|
ATE448246T1
(de)
*
|
1999-06-15 |
2009-11-15 |
Genentech Inc |
Sekretierte und transmembran-polypeptide sowie nukleinsäuren zu deren kodierung
|
|
US6960651B2
(en)
|
1999-06-29 |
2005-11-01 |
Millennium Pharmaceuticals, Inc. |
TANGO 332 polypeptides
|
|
US7001766B2
(en)
|
1999-07-20 |
2006-02-21 |
Curagen Corporation |
Nucleic acid sequences encoding human angiopoietin-like polypeptides
|
|
AU2390700A
(en)
*
|
1999-07-20 |
2001-02-05 |
Genentech Inc. |
Polypeptidic compositions and methods for the treatment of tumors
|
|
US6426199B1
(en)
*
|
1999-08-31 |
2002-07-30 |
Ortho-Mcneil Pharmaceutical, Inc. |
Dna
|
|
US6458564B1
(en)
|
1999-08-31 |
2002-10-01 |
Ortho-Mcneil Pharmaceutical, Inc. |
DNA encoding the human serine protease T
|
|
CN1560249A
(zh)
*
|
1999-09-08 |
2005-01-05 |
杰南技术公司 |
成纤维细胞生长因子-19(fgf-19)的核酸和多肽以及用于治疗肥胖的方法
|
|
AU7452300A
(en)
*
|
1999-10-01 |
2001-05-10 |
Kyowa Hakko Kogyo Co. Ltd. |
Shear stress-response dna
|
|
US6824780B1
(en)
|
1999-10-29 |
2004-11-30 |
Genentech, Inc. |
Anti-tumor antibody compositions and methods of use
|
|
US7115665B1
(en)
|
2000-11-16 |
2006-10-03 |
Onocozyme Pharma, Inc. |
Inhibitors of endo-exonuclease activity for treating cancer
|
|
EP1234877B1
(de)
*
|
1999-11-19 |
2010-06-02 |
Kumon, Hiromi |
Die zellvermehrung hemmendes protein, polynukleotid, antisens-polynukleotid und zellvermehrungshemmer, krebsdiagnostik, krebsheilmittel und zusammensetzungen zur gentherapie
|
|
EP1672070A3
(de)
*
|
1999-12-01 |
2006-10-04 |
Genentech, Inc. |
Sekretierte und transmembrane Polypeptide, sowie dafür codierende Nukleinsäuren
|
|
US20070087342A1
(en)
*
|
2000-01-14 |
2007-04-19 |
Incyte Corporation |
Secreted proteins
|
|
US7122631B2
(en)
|
2000-02-22 |
2006-10-17 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
WO2001062785A2
(en)
*
|
2000-02-24 |
2001-08-30 |
Oxford Glycosciences (Uk) Ltd. |
Protein and gene and their use for diagnosis and treatment of schizophrenia
|
|
AU3589101A
(en)
*
|
2000-02-24 |
2001-09-03 |
Oxford Glycosciences (Uk) Limited |
Dpi-6, a putative therapeutic target and biomarker in neuropsychiatric and neurological disorders
|
|
EP1918366A1
(de)
|
2000-02-26 |
2008-05-07 |
Artecel, Inc. |
Pluripotente Stammzellen aus Bindegewebszellen aus dem Fettgewebe und Verwendungen dafür
|
|
WO2001064882A2
(en)
*
|
2000-02-29 |
2001-09-07 |
Millennium Pharmaceuticals, Inc. |
1983, 52881, 2398, 45449, 50289, and 52872, g protein-coupled receptors and uses therefor
|
|
US6627423B2
(en)
|
2000-03-24 |
2003-09-30 |
Millennium Pharmaceuticals, Inc. |
21481, a novel dehydrogenase molecule and uses therefor
|
|
US6511834B1
(en)
|
2000-03-24 |
2003-01-28 |
Millennium Pharmaceuticals, Inc. |
32142,21481,25964,21686, novel human dehydrogenase molecules and uses therefor
|
|
WO2001075099A1
(en)
*
|
2000-04-04 |
2001-10-11 |
National Cancer Centre Of Singapore Pte Ltd |
Nucleic acid molecule encoding a uterine estrogen agonist-inducible protein
|
|
EP1309686A2
(de)
*
|
2000-06-30 |
2003-05-14 |
Millennium Pharmaceuticals, Inc. |
Slgp protein und dessen nukleinsäuren und verwendungen
|
|
DE10106835A1
(de)
*
|
2001-02-14 |
2002-09-05 |
Basf Lynx Bioscience Ag |
Signaltransduktionsproteine 15B3, 15B3-1 und 15B3-2 und zugrundeliegende DNA-Sequenzen
|
|
JP4272512B2
(ja)
|
2001-06-27 |
2009-06-03 |
キャンサー・リサーチ・テクノロジー・リミテッド |
癌
|
|
WO2003025162A2
(en)
*
|
2001-09-20 |
2003-03-27 |
Bayer Healthcare Ag |
Regulation of human prolyl 4-hydroxylase alpha subunit precursor
|
|
US20050089957A1
(en)
*
|
2001-10-19 |
2005-04-28 |
Audrey Goddard |
Compositions and methods for the diagnosis and treatment of inflammatory bowel disorders
|
|
AU2003227179A1
(en)
*
|
2002-02-08 |
2003-09-09 |
Amersham Biosciences K.K. |
Fused protein having glucuronyl transferase activity
|
|
EP1491628A4
(de)
*
|
2002-03-29 |
2006-10-18 |
Nat Inst Of Advanced Ind Scien |
Neue galactosetransferasen, peptide davon und diese codierende nukleinsäure
|
|
MXPA04012243A
(es)
|
2002-06-07 |
2005-02-25 |
Genentech Inc |
Composiciones y metodos para l diagnostico y tratamiento de tumores.
|
|
AU2003246085A1
(en)
*
|
2002-06-28 |
2004-01-19 |
Takeda Chemical Industries, Ltd. |
Diagnostics/preventives/remedies for respiratory diseases
|
|
EP1541677A4
(de)
|
2002-07-10 |
2007-06-27 |
Takeda Pharmaceutical |
Neue proteine und verwendung davon
|
|
CA2511556A1
(en)
*
|
2002-12-27 |
2004-07-29 |
Applied Research Systems Ars Holding N.V. |
Novel fibrillin-like polypeptides
|
|
WO2004085648A2
(en)
|
2003-03-19 |
2004-10-07 |
Biogen Idec Ma Inc. |
Nogo receptor binding protein
|
|
RU2005141341A
(ru)
*
|
2003-05-30 |
2006-06-10 |
Эйдженсис, Инк., Сша (Us) |
Полинуклеотид, родственный антигену стволовых клеток простаты (psca), и кодируемый им белок (пептид), гибридома и трансгенное животное для продуцирования антител, композиция для лечения, профилактики, диагностики и прогноза течения раковых заболеваний на их основе (варианты), способ определения их присутствия в исследуемом образце, способ генерации иммунного ответа, способ доставки цитотоксического или диагностического агента в клетку, способ ингибирования роста раковых клеток с их использованием
|
|
US7595379B2
(en)
|
2003-05-30 |
2009-09-29 |
Agensys, Inc. |
Antibodies and related molecules that bind to PSCA proteins
|
|
US7541442B2
(en)
|
2003-05-30 |
2009-06-02 |
Agensys, Inc. |
Antibodies and related molecules that bind to PSCA proteins
|
|
CA2550117A1
(en)
|
2003-12-16 |
2005-06-30 |
Genentech, Inc. |
Novel gene disruptions, compositions and methods relating thereto
|
|
ES2567634T3
(es)
|
2004-02-09 |
2016-04-25 |
Human Genome Sciences, Inc. |
Proteínas de fusión de albúmina
|
|
US20100031378A1
(en)
|
2008-08-04 |
2010-02-04 |
Edwards Joel A |
Novel gene disruptions, compositions and methods relating thereto
|
|
JP2007527712A
(ja)
*
|
2004-02-12 |
2007-10-04 |
レキシコン・ジェネティクス・インコーポレーテッド |
新規な遺伝子破壊、これに関する組成物と方法
|
|
GB0406215D0
(en)
|
2004-03-19 |
2004-04-21 |
Procure Therapeutics Ltd |
Prostate stem cell
|
|
JP4566603B2
(ja)
*
|
2004-03-31 |
2010-10-20 |
財団法人かずさディー・エヌ・エー研究所 |
細胞付着ポリペプチド
|
|
EP1744620A2
(de)
*
|
2004-05-12 |
2007-01-24 |
Genentech, Inc. |
Neue gendisruptionen, zusammensetzungen und verfahren hierfür
|
|
PT1776136E
(pt)
|
2004-06-24 |
2012-12-05 |
Biogen Idec Inc |
Tratamento de estados que envolvem desmielinização
|
|
MX2007001221A
(es)
|
2004-08-04 |
2007-03-23 |
Amgen Inc |
Anticuerpos para proteina dickkopf-1 (dkk-1).
|
|
US7544659B2
(en)
|
2004-08-13 |
2009-06-09 |
Genentech, Inc. |
Promotion of axonal regeneration
|
|
US7947436B2
(en)
|
2004-12-13 |
2011-05-24 |
Alethia Biotherapeutics Inc. |
Polynucleotides and polypeptide sequences involved in the process of bone remodeling
|
|
SI1904104T1
(sl)
|
2005-07-08 |
2013-12-31 |
Biogen Idec Ma Inc. |
Protitelesa SP35 in njihova uporaba
|
|
US8128926B2
(en)
|
2007-01-09 |
2012-03-06 |
Biogen Idec Ma Inc. |
Sp35 antibodies and uses thereof
|
|
EP2285961A4
(de)
*
|
2008-05-15 |
2012-10-17 |
Topigen Pharmaceuticals Inc |
Oligonukleotide zur behandlung von entzündungen und neoplastischer zellvermehrung
|
|
DK2982695T3
(da)
|
2008-07-09 |
2019-05-13 |
Biogen Ma Inc |
Sammensætninger, der omfatter antistoffer mod lingo eller fragmenter deraf
|
|
WO2010054096A1
(en)
*
|
2008-11-07 |
2010-05-14 |
The Cleveland Clinic Foundation |
Method for detecting and purifying pancreatic beta cells
|
|
JP5773879B2
(ja)
|
2008-11-25 |
2015-09-02 |
バイオジェン・エムエイ・インコーポレイテッドBiogen MA Inc. |
神経系の細胞の生存を促進するためのDR6およびp75のアンタゴニストの使用
|
|
WO2013006486A2
(en)
|
2011-07-01 |
2013-01-10 |
Ngm Biopharmaceuticals, Inc. |
Compositions, uses and methods for treatment of metabolic disorders and diseases
|
|
CN104470541A
(zh)
|
2012-05-14 |
2015-03-25 |
比奥根艾迪克Ma公司 |
用于治疗涉及运动神经元的疾患的lingo-2拮抗剂
|
|
US9290557B2
(en)
|
2012-11-28 |
2016-03-22 |
Ngm Biopharmaceuticals, Inc. |
Compositions comprising variants and fusions of FGF19 polypeptides
|
|
HK1214832A1
(zh)
|
2012-11-28 |
2016-08-05 |
恩格姆生物制药公司 |
用於代謝病症和疾病治療的組合物和方法
|
|
US9273107B2
(en)
|
2012-12-27 |
2016-03-01 |
Ngm Biopharmaceuticals, Inc. |
Uses and methods for modulating bile acid homeostasis and treatment of bile acid disorders and diseases
|
|
MX383664B
(es)
|
2012-12-27 |
2025-03-14 |
Ngm Biopharmaceuticals Inc |
Uso de un péptido para modular la homeostasis de los ácidos biliares o tratamiento de una enfermedad relacionada con los ácidos biliares.
|
|
WO2015065897A1
(en)
|
2013-10-28 |
2015-05-07 |
Ngm Biopharmaceuticals, Inc. |
Cancer models and associated methods
|
|
PT3097122T
(pt)
|
2014-01-24 |
2020-07-21 |
Ngm Biopharmaceuticals Inc |
Anticorpos de ligação de domínio 2 de beta klotho e métodos de utilização dos mesmos
|
|
US10398758B2
(en)
|
2014-05-28 |
2019-09-03 |
Ngm Biopharmaceuticals, Inc. |
Compositions comprising variants of FGF19 polypeptides and uses thereof for the treatment of hyperglycemic conditions
|
|
WO2015195509A2
(en)
|
2014-06-16 |
2015-12-23 |
Ngm Biopharmaceuticals, Inc. |
Methods and uses for modulating bile acid homeostasis and treatment of bile acid disorders and diseases
|
|
US9616114B1
(en)
|
2014-09-18 |
2017-04-11 |
David Gordon Bermudes |
Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
|
|
CN114129709A
(zh)
|
2014-10-23 |
2022-03-04 |
恩格姆生物制药公司 |
包含肽变异体的药物组合物及其使用方法
|
|
US10434144B2
(en)
|
2014-11-07 |
2019-10-08 |
Ngm Biopharmaceuticals, Inc. |
Methods for treatment of bile acid-related disorders and prediction of clinical sensitivity to treatment of bile acid-related disorders
|
|
JP2018504400A
(ja)
|
2015-01-08 |
2018-02-15 |
バイオジェン・エムエイ・インコーポレイテッドBiogen MA Inc. |
Lingo‐1拮抗薬及び脱髄障害の治療のための使用
|
|
US10676723B2
(en)
|
2015-05-11 |
2020-06-09 |
David Gordon Bermudes |
Chimeric protein toxins for expression by therapeutic bacteria
|
|
WO2017019957A2
(en)
|
2015-07-29 |
2017-02-02 |
Ngm Biopharmaceuticals, Inc. |
Binding proteins and methods of use thereof
|
|
JP6728352B2
(ja)
|
2015-11-09 |
2020-07-22 |
エヌジーエム バイオファーマシューティカルス,インコーポレーテッド |
胆汁酸に関係した障害の治療方法
|
|
EP3503882A4
(de)
|
2016-08-26 |
2020-07-29 |
NGM Biopharmaceuticals, Inc. |
Verfahren zur behandlung von fibroblastenwachstumsfaktor-19-vermittelten karzinomen und tumoren
|
|
US11180535B1
(en)
|
2016-12-07 |
2021-11-23 |
David Gordon Bermudes |
Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
|
|
US11129906B1
(en)
|
2016-12-07 |
2021-09-28 |
David Gordon Bermudes |
Chimeric protein toxins for expression by therapeutic bacteria
|
|
CN107271337B
(zh)
*
|
2017-04-24 |
2023-09-15 |
中国人民解放军军事医学科学院卫生装备研究所 |
一种人体肺泡气溶胶沉积测量实验系统
|