ATE417063T1 - Sekretierte transmembranproteine und dafür kodierende nukleinsäuren - Google Patents

Sekretierte transmembranproteine und dafür kodierende nukleinsäuren

Info

Publication number
ATE417063T1
ATE417063T1 AT05011885T AT05011885T ATE417063T1 AT E417063 T1 ATE417063 T1 AT E417063T1 AT 05011885 T AT05011885 T AT 05011885T AT 05011885 T AT05011885 T AT 05011885T AT E417063 T1 ATE417063 T1 AT E417063T1
Authority
AT
Austria
Prior art keywords
polypeptides
nucleic acids
present
transmembrane proteins
acids coding
Prior art date
Application number
AT05011885T
Other languages
English (en)
Inventor
Luc Desnoyers
Dan L Eaton
Audrey Goddard
Paul J Godowski
Austin L Gurney
James Pan
Timothy A Stewart
Colin K Watanabe
William I Wood
Zemin Zhang
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of ATE417063T1 publication Critical patent/ATE417063T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Obesity (AREA)
  • Biophysics (AREA)
  • Emergency Medicine (AREA)
  • Biotechnology (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
  • Endocrinology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
AT05011885T 1999-03-23 2000-03-01 Sekretierte transmembranproteine und dafür kodierende nukleinsäuren ATE417063T1 (de)

Applications Claiming Priority (17)

Application Number Priority Date Filing Date Title
US12577899P 1999-03-23 1999-03-23
US12577499P 1999-03-23 1999-03-23
US12582699P 1999-03-24 1999-03-24
US12703599P 1999-03-31 1999-03-31
US12770699P 1999-04-05 1999-04-05
US13035999P 1999-04-21 1999-04-21
US13127099P 1999-04-27 1999-04-27
US13129199P 1999-04-27 1999-04-27
US13127299P 1999-04-27 1999-04-27
US13238399P 1999-05-04 1999-05-04
US13237199P 1999-05-04 1999-05-04
US13237999P 1999-05-04 1999-05-04
US13575099P 1999-05-25 1999-05-25
US13816699P 1999-06-08 1999-06-08
US14479199P 1999-07-20 1999-07-20
US14697099P 1999-08-03 1999-08-03
US17026299P 1999-12-09 1999-12-09

Publications (1)

Publication Number Publication Date
ATE417063T1 true ATE417063T1 (de) 2008-12-15

Family

ID=27586019

Family Applications (4)

Application Number Title Priority Date Filing Date
AT06005614T ATE449108T1 (de) 1999-03-23 2000-03-01 Ausgeschiedene und transmembrane polypeptide und dafür kodierende nukleinsäure
AT05011885T ATE417063T1 (de) 1999-03-23 2000-03-01 Sekretierte transmembranproteine und dafür kodierende nukleinsäuren
AT00917717T ATE329023T1 (de) 1999-03-23 2000-03-01 Ausgeschiedene und transmembran-polypeptide und dafür kodierende nukleinsäure
AT05014619T ATE409228T1 (de) 1999-03-23 2000-03-01 Ausgeschiedene und transmembranpolypeptide und dafür kodierende nukleinsäure

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT06005614T ATE449108T1 (de) 1999-03-23 2000-03-01 Ausgeschiedene und transmembrane polypeptide und dafür kodierende nukleinsäure

Family Applications After (2)

Application Number Title Priority Date Filing Date
AT00917717T ATE329023T1 (de) 1999-03-23 2000-03-01 Ausgeschiedene und transmembran-polypeptide und dafür kodierende nukleinsäure
AT05014619T ATE409228T1 (de) 1999-03-23 2000-03-01 Ausgeschiedene und transmembranpolypeptide und dafür kodierende nukleinsäure

Country Status (11)

Country Link
EP (4) EP1616878B1 (de)
JP (8) JP4174183B2 (de)
KR (1) KR100504305B1 (de)
AT (4) ATE449108T1 (de)
AU (1) AU764092B2 (de)
CA (1) CA2361221A1 (de)
DK (3) DK1609863T3 (de)
ES (3) ES2314521T3 (de)
NZ (3) NZ527292A (de)
PT (3) PT1169442E (de)
WO (1) WO2000056889A2 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6525174B1 (en) 1997-06-06 2003-02-25 Human Genome Sciences, Inc. Precerebellin-like protein
US7105639B2 (en) 1998-05-15 2006-09-12 Genentech, Inc. Anti-PRO 4405 antibodies
IL143593A0 (en) * 1998-12-23 2002-04-21 Genentech Inc Il-1 related polypeptides
DK1200590T3 (da) 1999-08-12 2009-03-16 Agensys Inc C-type lectin-transmembran-antigen, der udtrykkes ved human prostatacancer, og anvendelser deraf
US7842458B2 (en) * 1999-08-12 2010-11-30 Agensys, Inc. Nucleic acids and corresponding proteins entitled 58P1D12 useful in treatment and detection of cancer
WO2001059120A2 (en) * 2000-02-08 2001-08-16 Amgen, Inc. Il-17 like molecules and uses thereof
US7067297B2 (en) 2000-02-15 2006-06-27 Chugai Seiyaku Kabushiki Kaisha Mannosyltransferase polypeptides and polynucleotides encoding them and methods for making and using them
EP1259819A2 (de) * 2000-02-24 2002-11-27 Oxford GlycoSciences (UK) Limited Diagnose von bipolarer affektiver störung und unipolarer depression
WO2001073022A1 (fr) * 2000-03-29 2001-10-04 Kyowa Hakko Kogyo Co., Ltd. Gene associe a la glomerulonephrite proliferative
US6692748B2 (en) 2000-12-07 2004-02-17 Zymogenetics, Inc. Adipocyte complement related protein zacrp3x2 and nucleic acids encoding zacrp3x2
JP4344519B2 (ja) * 2000-12-28 2009-10-14 旭化成ファーマ株式会社 ＮＦ−κＢ活性化遺伝子
WO2003000729A2 (en) * 2001-06-20 2003-01-03 Genentech, Inc. Secreted polypeptide and their use in the treatment of bone disorders
US20060058507A1 (en) * 2002-05-10 2006-03-16 Genset S.A. Krib polynucleotides and polypeptides and uses thereof in the treatment of metabolic disorders
EP1514926A4 (de) * 2002-05-31 2006-01-11 Hidetoshi Inoko Mit entzündlicher hauterkrankung verbundenes slurp-2-gen und dessen nutzung
DE10254601A1 (de) 2002-11-22 2004-06-03 Ganymed Pharmaceuticals Ag Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung
DE102004024617A1 (de) 2004-05-18 2005-12-29 Ganymed Pharmaceuticals Ag Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung
EP1790664A1 (de) 2005-11-24 2007-05-30 Ganymed Pharmaceuticals AG Monoklonale Antikörper gegen Claudin-18 zur Behandlung von Krebs
EP2069793B9 (de) 2006-08-29 2017-08-16 Oxford BioTherapeutics Ltd Identifizierung von mit hepatozellulärem karzinom, glioblastom und lungenkrebs assoziiertem protein
ES2639026T3 (es) 2009-03-05 2017-10-25 Oxford Biotherapeutics Ltd. Anticuerpos totalmente humanos específicos para CADM1
WO2013167153A1 (en) 2012-05-09 2013-11-14 Ganymed Pharmaceuticals Ag Antibodies useful in cancer diagnosis
KR101695792B1 (ko) * 2014-09-04 2017-01-12 디오셀 주식회사 신규 세포막 투과 펩티드 및 생리활성 물질 전달체로서의 그의 용도

Family Cites Families (18)

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NZ207394A (en) 1983-03-08 1987-03-06 Commw Serum Lab Commission Detecting or determining sequence of amino acids
US5206161A (en) 1991-02-01 1993-04-27 Genentech, Inc. Human plasma carboxypeptidase B
EP0791009A4 (de) * 1994-11-07 2003-03-05 Merck & Co Inc Modifizierter neuropeptid-y-rezeptor
AU1532697A (en) * 1996-01-12 1997-08-01 Genetics Institute Inc. Beta-chemokine, h1305 (mcp-2)
CA2296287A1 (en) 1997-08-01 1999-02-11 Genset 5' ests for secreted proteins expressed in prostate
DE69837761T2 (de) * 1997-08-01 2008-01-17 Serono Genetics Institute S.A. 5' ests für sekretierte proteine aus gehirngeweben
ES2330903T3 (es) 1997-12-17 2009-12-16 Serono Genetics Institute S.A. Adncs extendidos para proteinas secretadas.
AU764571B2 (en) 1998-04-09 2003-08-21 Genset S.A. 5' ESTs and encoded human proteins
JP2002512798A (ja) * 1998-04-29 2002-05-08 ジェネシス リサーチ アンド デベロップメント コーポレイション リミテッド 皮膚細胞から単離したポリヌクレオチドおよびその使用方法
CA2362423A1 (en) 1998-12-17 2000-06-22 Human Genome Sciences, Inc. 47 human secreted proteins
CA2296792A1 (en) 1999-02-26 2000-08-26 Genset S.A. Expressed sequence tags and encoded human proteins
JP2004507202A (ja) * 1999-03-31 2004-03-11 キュラジェン　コーポレイション ポリペプチドをコードするオープンリーディングフレームを含む核酸；「ｏｒｆｘ」
CA2377263A1 (en) 1999-06-23 2000-12-28 Curagen Corporation Polynucleotides and polypeptides encoded thereby
EP1074617A3 (de) * 1999-07-29 2004-04-21 Research Association for Biotechnology Primers für Synthese von ganzen-Länge cDNS und deren Anwendung
CA2311201A1 (en) * 1999-08-05 2001-02-05 Genset S.A. Ests and encoded human proteins
DK1200590T3 (da) * 1999-08-12 2009-03-16 Agensys Inc C-type lectin-transmembran-antigen, der udtrykkes ved human prostatacancer, og anvendelser deraf
WO2001012660A2 (en) * 1999-08-17 2001-02-22 Sagami Chemical Research Center HUMAN PROTEINS HAVING HYDROPHOBIC DOMAINS AND DNAs ENCODING THESE PROTEINS
US6635742B1 (en) 2000-01-25 2003-10-21 Nuvelo, Inc. Antibodies specific for semaphorin-like polypeptides

Also Published As

Publication number Publication date
JP2006101880A (ja) 2006-04-20
KR100504305B1 (ko) 2005-07-28
EP1609863A2 (de) 2005-12-28
EP1616878A1 (de) 2006-01-18
EP1688430B1 (de) 2009-11-18
EP1169442B1 (de) 2006-06-07
WO2000056889A2 (en) 2000-09-28
JP2006101881A (ja) 2006-04-20
DK1169442T3 (da) 2006-10-16
ES2269125T3 (es) 2007-04-01
EP1688430A2 (de) 2006-08-09
JP4398937B2 (ja) 2010-01-13
EP1688430A3 (de) 2006-11-02
JP4174183B2 (ja) 2008-10-29
EP1169442A2 (de) 2002-01-09
JP2006115847A (ja) 2006-05-11
CA2361221A1 (en) 2000-09-28
AU3864800A (en) 2000-10-09
JP4392759B2 (ja) 2010-01-06
KR20010112927A (ko) 2001-12-22
ATE329023T1 (de) 2006-06-15
EP1609863A3 (de) 2006-04-12
AU764092B2 (en) 2003-08-07
PT1169442E (pt) 2006-10-31
JP2006158392A (ja) 2006-06-22
JP2003527074A (ja) 2003-09-16
JP2006136325A (ja) 2006-06-01
NZ536320A (en) 2006-04-28
EP1616878B1 (de) 2008-12-10
DK1616878T3 (da) 2009-03-30
EP1609863B1 (de) 2008-09-24
PT1609863E (pt) 2009-01-02
ES2314521T3 (es) 2009-03-16
WO2000056889A3 (en) 2001-04-26
JP2010075189A (ja) 2010-04-08
DK1609863T3 (da) 2008-12-15
PT1616878E (pt) 2009-03-18
JP2006115848A (ja) 2006-05-11
JP4392760B2 (ja) 2010-01-06
NZ527292A (en) 2005-03-24
JP4402034B2 (ja) 2010-01-20
ATE409228T1 (de) 2008-10-15
ATE449108T1 (de) 2009-12-15
ES2319202T3 (es) 2009-05-05
NZ527293A (en) 2005-01-28

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