JP2003522514A5 - - Google Patents
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- Publication number
- JP2003522514A5 JP2003522514A5 JP2000520572A JP2000520572A JP2003522514A5 JP 2003522514 A5 JP2003522514 A5 JP 2003522514A5 JP 2000520572 A JP2000520572 A JP 2000520572A JP 2000520572 A JP2000520572 A JP 2000520572A JP 2003522514 A5 JP2003522514 A5 JP 2003522514A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- protein
- acid molecule
- seq
- nucleotide sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000039446 nucleic acids Human genes 0.000 description 11
- 108020004707 nucleic acids Proteins 0.000 description 11
- 150000007523 nucleic acids Chemical class 0.000 description 11
- 102000004169 proteins and genes Human genes 0.000 description 10
- 108090000623 proteins and genes Proteins 0.000 description 10
- 239000002773 nucleotide Substances 0.000 description 3
- 125000003729 nucleotide group Chemical group 0.000 description 3
- 241000588653 Neisseria Species 0.000 description 2
- 125000003275 alpha amino acid group Chemical group 0.000 description 2
- 230000002163 immunogen Effects 0.000 description 2
- 230000000295 complement effect Effects 0.000 description 1
Applications Claiming Priority (15)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9723516.2A GB9723516D0 (enExample) | 1997-11-06 | 1997-11-06 | |
| GB9723516.2 | 1997-11-06 | ||
| GB9724190.5 | 1997-11-14 | ||
| GBGB9724190.5A GB9724190D0 (enExample) | 1997-11-14 | 1997-11-14 | |
| GBGB9724386.9A GB9724386D0 (enExample) | 1997-11-18 | 1997-11-18 | |
| GB9724386.9 | 1997-11-18 | ||
| GB9725158.1 | 1997-11-27 | ||
| GBGB9725158.1A GB9725158D0 (enExample) | 1997-11-27 | 1997-11-27 | |
| GB9726147.3 | 1997-12-10 | ||
| GBGB9726147.3A GB9726147D0 (en) | 1997-12-10 | 1997-12-10 | Antigens |
| GBGB9800759.4A GB9800759D0 (enExample) | 1998-01-14 | 1998-01-14 | |
| GB9800759.4 | 1998-01-14 | ||
| GB9819016.8 | 1998-09-01 | ||
| GBGB9819016.8A GB9819016D0 (enExample) | 1998-09-01 | 1998-09-01 | |
| PCT/IB1998/001665 WO1999024578A2 (en) | 1997-11-06 | 1998-10-09 | Neisserial antigens |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005290551A Division JP2006089488A (ja) | 1997-11-06 | 2005-10-03 | ナイセリア抗原 |
| JP2009245980A Division JP2010046089A (ja) | 1997-11-06 | 2009-10-26 | ナイセリア抗原 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2003522514A JP2003522514A (ja) | 2003-07-29 |
| JP2003522514A5 true JP2003522514A5 (enExample) | 2009-04-30 |
| JP4472866B2 JP4472866B2 (ja) | 2010-06-02 |
Family
ID=27562941
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000520572A Expired - Fee Related JP4472866B2 (ja) | 1997-11-06 | 1998-10-09 | ナイセリア抗原 |
| JP2005290551A Withdrawn JP2006089488A (ja) | 1997-11-06 | 2005-10-03 | ナイセリア抗原 |
| JP2009245980A Withdrawn JP2010046089A (ja) | 1997-11-06 | 2009-10-26 | ナイセリア抗原 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005290551A Withdrawn JP2006089488A (ja) | 1997-11-06 | 2005-10-03 | ナイセリア抗原 |
| JP2009245980A Withdrawn JP2010046089A (ja) | 1997-11-06 | 2009-10-26 | ナイセリア抗原 |
Country Status (10)
| Country | Link |
|---|---|
| EP (3) | EP1900818A3 (enExample) |
| JP (3) | JP4472866B2 (enExample) |
| CN (1) | CN1263854C (enExample) |
| AT (1) | ATE476508T1 (enExample) |
| AU (1) | AU9363798A (enExample) |
| BR (1) | BR9813930A (enExample) |
| CA (2) | CA2308606A1 (enExample) |
| CY (1) | CY1110880T1 (enExample) |
| DE (1) | DE69841807D1 (enExample) |
| WO (1) | WO1999024578A2 (enExample) |
Families Citing this family (129)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2324093A (en) | 1996-01-04 | 1998-10-14 | Rican Limited | Helicobacter pylori bacterioferritin |
| CA2266656A1 (en) | 1996-09-17 | 1998-03-26 | Chiron Corporation | Compositions and methods for treating intracellular diseases |
| US6914131B1 (en) | 1998-10-09 | 2005-07-05 | Chiron S.R.L. | Neisserial antigens |
| US8129500B2 (en) | 1997-12-10 | 2012-03-06 | Csl Limited | Porphyromonas gingivalis polypeptides and nucleotides |
| AUPP083997A0 (en) | 1997-12-10 | 1998-01-08 | Csl Limited | Porphyromonas gingivalis nucleotides |
| GB9808866D0 (en) * | 1998-04-24 | 1998-06-24 | Smithkline Beecham Biolog | Novel compounds |
| EP2261341A3 (en) | 1998-05-01 | 2012-01-04 | Novartis Vaccines and Diagnostics, Inc. | Neisseria meningitidis antigens and compositions |
| GB9814902D0 (en) * | 1998-07-10 | 1998-09-09 | Univ Nottingham | Screening of neisserial vaccine candidates against pathogenic neisseria |
| GB9818004D0 (en) * | 1998-08-18 | 1998-10-14 | Smithkline Beecham Biolog | Novel compounds |
| US6610306B2 (en) | 1998-10-22 | 2003-08-26 | The University Of Montana | OMP85 protein of neisseria meningitidis, compositions containing the same and methods of use thereof |
| US10967045B2 (en) | 1998-11-02 | 2021-04-06 | Secretary of State for Health and Social Care | Multicomponent meningococcal vaccine |
| JP2004537956A (ja) | 1999-01-22 | 2004-12-24 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 新規化合物 |
| AU3164600A (en) | 1999-03-12 | 2000-10-04 | Smithkline Beecham Biologicals (Sa) | Novel compounds |
| EP1228217B1 (en) | 1999-04-30 | 2012-11-21 | Novartis Vaccines and Diagnostics S.r.l. | Conserved neisserial antigens |
| EP1860191A3 (en) | 1999-05-19 | 2008-02-13 | Novartis Vaccines and Diagnostics S.r.l. | Combination neisserial compositions |
| GB9911683D0 (en) * | 1999-05-19 | 1999-07-21 | Chiron Spa | Antigenic peptides |
| GB9918003D0 (en) * | 1999-07-30 | 1999-09-29 | Smithkline Beecham Biolog | Novel compounds |
| DE60044005D1 (de) | 1999-11-29 | 2010-04-22 | Novartis Vaccines & Diagnostic | 85 kDa Antigen von Neisseria |
| GB9928196D0 (en) * | 1999-11-29 | 2000-01-26 | Chiron Spa | Combinations of B, C and other antigens |
| EP2275129A3 (en) | 2000-01-17 | 2013-11-06 | Novartis Vaccines and Diagnostics S.r.l. | Outer membrane vesicle (OMV) vaccine comprising N. meningitidis serogroup B outer membrane proteins |
| IL150822A0 (en) | 2000-01-25 | 2003-02-12 | Univ Queensland | PROTEINS COMPRISING CONSERVED REGIONS OF NEISSERIA MENINGITIDIS SURFACE ANTIGEN NhhA |
| CN101139590B (zh) * | 2000-02-28 | 2012-07-18 | 启龙股份公司 | 奈瑟球菌蛋白质的杂交表达 |
| GB0011108D0 (en) * | 2000-05-08 | 2000-06-28 | Microscience Ltd | Virulence gene and protein and their use |
| ES2519440T3 (es) | 2000-07-27 | 2014-11-07 | Children's Hospital & Research Center At Oakland | Vacunas para la protección de amplio espectro contra enfermedades causadas por Neisseria meningitidis |
| US6830898B2 (en) * | 2000-08-24 | 2004-12-14 | Omnigene Bioproducts, Inc. | Microorganisms and assays for the identification of antibiotics |
| AU2002211999A1 (en) | 2000-10-02 | 2002-04-15 | Id Biomedical Corporation | Haemophilus influenzae antigens and corresponding DNA fragments |
| WO2002034771A2 (en) | 2000-10-27 | 2002-05-02 | Chiron Srl | Nucleic acids and proteins from streptococcus groups a & b |
| WO2002060936A2 (en) * | 2001-01-31 | 2002-08-08 | University Of Iowa Research Foundation | Vaccine and compositions for the prevention and treatment of neisserial infections |
| US7261901B2 (en) | 2001-01-31 | 2007-08-28 | University Of Iowa Research Foundation | Vaccine and compositions for the prevention and treatment of neisserial infections |
| GB0107658D0 (en) | 2001-03-27 | 2001-05-16 | Chiron Spa | Streptococcus pneumoniae |
| GB0107661D0 (en) | 2001-03-27 | 2001-05-16 | Chiron Spa | Staphylococcus aureus |
| GB0109289D0 (en) * | 2001-04-12 | 2001-05-30 | Glaxosmithkline Biolog Sa | Novel compounds |
| ES2316563T3 (es) | 2001-05-15 | 2009-04-16 | Id Biomedical Corporation | Antigenos de moraxella (branhamella) catarrhalis. |
| CA2448066A1 (en) | 2001-05-31 | 2002-12-12 | Chiron Corporation | Chimeric alphavirus replicon particles |
| GB0115176D0 (en) | 2001-06-20 | 2001-08-15 | Chiron Spa | Capular polysaccharide solubilisation and combination vaccines |
| GB0118249D0 (en) | 2001-07-26 | 2001-09-19 | Chiron Spa | Histidine vaccines |
| GB0121591D0 (en) | 2001-09-06 | 2001-10-24 | Chiron Spa | Hybrid and tandem expression of neisserial proteins |
| MXPA04000653A (es) | 2001-07-27 | 2004-11-22 | Chiron Srl | Adhesinas de meningococcus nada, app y orf 40. |
| AR045702A1 (es) | 2001-10-03 | 2005-11-09 | Chiron Corp | Composiciones de adyuvantes. |
| CN100354297C (zh) * | 2001-10-03 | 2007-12-12 | 希龙公司 | 辅助的脑膜炎球菌组合物 |
| MX339524B (es) | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
| GB0129007D0 (en) * | 2001-12-04 | 2002-01-23 | Chiron Spa | Adjuvanted antigenic meningococcal compositions |
| ES2312649T3 (es) | 2001-12-12 | 2009-03-01 | Novartis Vaccines And Diagnostics S.R.L. | Inmunizacion frente a chlamydia trachomatis. |
| EP1531796B1 (en) | 2002-02-20 | 2016-09-28 | GlaxoSmithKline Biologicals SA | Microparticles with adsorbed polypeptide-containing molecules |
| GB0220194D0 (en) | 2002-08-30 | 2002-10-09 | Chiron Spa | Improved vesicles |
| US7785608B2 (en) | 2002-08-30 | 2010-08-31 | Wyeth Holdings Corporation | Immunogenic compositions for the prevention and treatment of meningococcal disease |
| DE60335477D1 (de) | 2002-10-11 | 2011-02-03 | Novartis Vaccines & Diagnostic | Polypeptidimpstoffe zum breiten schutz gegen hypervirulente meningokokken-linien |
| US20070059329A1 (en) | 2002-11-15 | 2007-03-15 | Nathalie Norais | Unexpected surface proteins in meningococcus |
| GB0227346D0 (en) | 2002-11-22 | 2002-12-31 | Chiron Spa | 741 |
| WO2004060396A2 (en) | 2002-12-27 | 2004-07-22 | Chiron Corporation | Immunogenic compositions containing phospholpid |
| PT2172213E (pt) | 2003-01-30 | 2013-06-03 | Novartis Ag | Vacinas injetáveis contra múltiplos serogrupos meningocócicos |
| JP2006519605A (ja) * | 2003-03-06 | 2006-08-31 | チルドレンズ ホスピタル, インコーポレイテッド | 類型不能haemophilusinfluenzaeの中耳炎単離株の遺伝子 |
| US7893096B2 (en) | 2003-03-28 | 2011-02-22 | Novartis Vaccines And Diagnostics, Inc. | Use of small molecule compounds for immunopotentiation |
| GB0308198D0 (en) | 2003-04-09 | 2003-05-14 | Chiron Srl | ADP-ribosylating bacterial toxin |
| US7731967B2 (en) | 2003-04-30 | 2010-06-08 | Novartis Vaccines And Diagnostics, Inc. | Compositions for inducing immune responses |
| CA2528007C (en) | 2003-06-02 | 2012-03-27 | Chiron Corporation | Immunogenic compositions based on microparticles comprising adsorbed toxoid and a polysaccharide-containing antigen |
| ATE506963T1 (de) | 2003-10-02 | 2011-05-15 | Novartis Vaccines & Diagnostic | Kombinationsimpfstoffe gegen meningitis |
| GB0323103D0 (en) | 2003-10-02 | 2003-11-05 | Chiron Srl | De-acetylated saccharides |
| GB0408977D0 (en) | 2004-04-22 | 2004-05-26 | Chiron Srl | Immunising against meningococcal serogroup Y using proteins |
| EP2583678A3 (en) | 2004-06-24 | 2013-11-13 | Novartis Vaccines and Diagnostics, Inc. | Small molecule immunopotentiators and assays for their detection |
| EP1784211A4 (en) | 2004-07-29 | 2010-06-30 | Novartis Vaccines & Diagnostic | IMMUNOGENIC COMPOSITIONS FOR GRAMPOSITIVE BACTERIA SUCH AS STREPTOCOCCUS AGALACTIAE |
| DK2682126T3 (en) | 2005-01-27 | 2017-02-27 | Children's Hospital & Res Center At Oakland | GNA1870-based vesicle vaccines for broad-spectrum protection against diseases caused by Neisseria meningitidis |
| GB0502096D0 (en) | 2005-02-01 | 2005-03-09 | Chiron Srl | Purification of streptococcal capsular polysaccharide |
| GB0502095D0 (en) | 2005-02-01 | 2005-03-09 | Chiron Srl | Conjugation of streptococcal capsular saccharides |
| US8062644B2 (en) | 2005-02-18 | 2011-11-22 | Novartis Vaccines & Diagnostics Srl. | Immunogens from uropathogenic Escherichia coli |
| ES2595363T3 (es) | 2005-02-18 | 2016-12-29 | J. Craig Venter Institute, Inc. | Sepsis asociada a las proteínas y los ácidos nucleicos de meningitis / Escherichia coli |
| CA2612240A1 (en) | 2005-06-16 | 2006-12-28 | Children's Hospital, Inc. | Genes of an otitis media isolate of nontypeable haemophilus influenzae |
| CN101355960A (zh) | 2005-10-18 | 2009-01-28 | 诺华疫苗和诊断公司 | 使用α病毒复制子颗粒进行粘膜和全身免疫 |
| WO2007081447A2 (en) | 2005-11-22 | 2007-07-19 | Novartis Vaccines And Diagnostics, Inc. | Norovirus and sapovirus antigens |
| GB0524066D0 (en) | 2005-11-25 | 2006-01-04 | Chiron Srl | 741 ii |
| CA2637598A1 (en) | 2006-01-18 | 2007-02-14 | University Of Chicago | Compositions and methods related to staphylococcal bacterium proteins |
| CA2646539A1 (en) | 2006-03-23 | 2007-09-27 | Novartis Ag | Imidazoquinoxaline compounds as immunomodulators |
| WO2007110602A1 (en) * | 2006-03-28 | 2007-10-04 | The University Of Nottingham | Immunogenic compositions |
| WO2008001224A2 (en) | 2006-06-29 | 2008-01-03 | Novartis Ag | Polypeptides from neisseria meningitidis |
| WO2008020330A2 (en) | 2006-08-16 | 2008-02-21 | Novartis Ag | Immunogens from uropathogenic escherichia coli |
| AR064642A1 (es) | 2006-12-22 | 2009-04-15 | Wyeth Corp | Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi |
| GB0700562D0 (en) | 2007-01-11 | 2007-02-21 | Novartis Vaccines & Diagnostic | Modified Saccharides |
| GB0713880D0 (en) | 2007-07-17 | 2007-08-29 | Novartis Ag | Conjugate purification |
| AU2008299376B2 (en) | 2007-09-12 | 2013-02-28 | Glaxosmithkline Biologicals S.A. | GAS57 mutant antigens and GAS57 antibodies |
| NZ584683A (en) | 2007-10-19 | 2012-05-25 | Novartis Ag | Neisseria meningitidis serogroup B vaccine formulations |
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| NZ586430A (en) | 2007-12-21 | 2012-09-28 | Novartis Ag | Mutant forms of streptolysin o (slo) |
| US9579372B2 (en) | 2008-02-21 | 2017-02-28 | Glaxosmithkline Biologicals Sa | Meningococcal fHBP polypeptides |
| PL2268618T3 (pl) | 2008-03-03 | 2015-11-30 | Novartis Ag | Związki i kompozycje jako modulatory aktywności receptorów TLR |
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| BRPI1005670A8 (pt) | 2009-01-05 | 2017-12-26 | Epitogenesis Inc | composições adjuvantes e processos de uso. |
| US8465751B2 (en) | 2009-01-12 | 2013-06-18 | Novartis Ag | Cna—B domain antigens in vaccines against gram positive bacteria |
| ITMI20090946A1 (it) | 2009-05-28 | 2010-11-29 | Novartis Ag | Espressione di proteine ricombinanti |
| CN102762226A (zh) | 2009-06-10 | 2012-10-31 | 诺华有限公司 | 含苯并萘啶的疫苗 |
| WO2011008400A2 (en) | 2009-06-16 | 2011-01-20 | Novartis Ag | High-throughput complement-mediated antibody-dependent and opsonic bactericidal assays |
| BR112012004275A2 (pt) | 2009-08-27 | 2016-11-16 | Novartis Ag | polipeptídios híbridos incluindo sequências meningocócicas de fhbp |
| WO2011026111A1 (en) | 2009-08-31 | 2011-03-03 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Oral delivery of a vaccine to the large intestine to induce mucosal immunity |
| ES2443952T3 (es) | 2009-09-02 | 2014-02-21 | Novartis Ag | Composiciones inmunógenas que incluyen moduladores de la actividad de TLR |
| JO3257B1 (ar) | 2009-09-02 | 2018-09-16 | Novartis Ag | مركبات وتركيبات كمعدلات لفاعلية tlr |
| MX373250B (es) | 2009-09-30 | 2020-05-04 | Glaxosmithkline Biologicals S A Star | Conjugación de polisacáridos capsulares de tipo 5 y de tipo 8 de staphylococcus aureus. |
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| WO2011127360A1 (en) | 2010-04-08 | 2011-10-13 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | B-cell antigen presenting cell assay |
| CN102933267B (zh) | 2010-05-28 | 2015-05-27 | 泰特里斯在线公司 | 交互式混合异步计算机游戏基础结构 |
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| PT3246044T (pt) | 2010-08-23 | 2021-02-15 | Wyeth Llc | Formulações estáveis de antigénios de rlp2086 de neisseria meningitidis |
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| JP6499446B2 (ja) | 2011-06-24 | 2019-04-10 | エピットジェネシス・インコーポレーテッド | 抗原特異的免疫モジュレーターとして選択担体、ビタミン、タンニンおよびフラボノイドの組み合わせを含有する医薬組成物 |
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| EP3439704A1 (en) | 2016-04-05 | 2019-02-13 | GSK Vaccines S.r.l. | Immunogenic compositions |
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| US11464845B2 (en) | 2017-07-21 | 2022-10-11 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Neisseria meningitidis immunogenic compositions |
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1998
- 1998-10-09 AT AT98946675T patent/ATE476508T1/de not_active IP Right Cessation
- 1998-10-09 CA CA002308606A patent/CA2308606A1/en not_active Abandoned
- 1998-10-09 CA CA002671261A patent/CA2671261A1/en not_active Abandoned
- 1998-10-09 CN CNB988128446A patent/CN1263854C/zh not_active Expired - Fee Related
- 1998-10-09 BR BRPI9813930-4A patent/BR9813930A/pt not_active Application Discontinuation
- 1998-10-09 DE DE69841807T patent/DE69841807D1/de not_active Expired - Lifetime
- 1998-10-09 EP EP07075379A patent/EP1900818A3/en not_active Withdrawn
- 1998-10-09 JP JP2000520572A patent/JP4472866B2/ja not_active Expired - Fee Related
- 1998-10-09 WO PCT/IB1998/001665 patent/WO1999024578A2/en not_active Ceased
- 1998-10-09 EP EP10179785A patent/EP2278006A3/en not_active Withdrawn
- 1998-10-09 AU AU93637/98A patent/AU9363798A/en not_active Abandoned
- 1998-10-09 EP EP98946675A patent/EP1029052B1/en not_active Expired - Lifetime
-
2005
- 2005-10-03 JP JP2005290551A patent/JP2006089488A/ja not_active Withdrawn
-
2009
- 2009-10-26 JP JP2009245980A patent/JP2010046089A/ja not_active Withdrawn
-
2010
- 2010-11-04 CY CY20101100997T patent/CY1110880T1/el unknown
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