JP2002519061A5 - - Google Patents
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- Publication number
- JP2002519061A5 JP2002519061A5 JP2000558205A JP2000558205A JP2002519061A5 JP 2002519061 A5 JP2002519061 A5 JP 2002519061A5 JP 2000558205 A JP2000558205 A JP 2000558205A JP 2000558205 A JP2000558205 A JP 2000558205A JP 2002519061 A5 JP2002519061 A5 JP 2002519061A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- nos
- group
- nucleic acid
- encoded polypeptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
Applications Claiming Priority (15)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA199800904 | 1998-07-06 | ||
| US9222998P | 1998-07-09 | 1998-07-09 | |
| US60/092,229 | 1998-07-09 | ||
| DKPA199801048 | 1998-08-19 | ||
| US9777498P | 1998-08-25 | 1998-08-25 | |
| US60/097,774 | 1998-08-25 | ||
| DKPA199801265 | 1998-10-06 | ||
| US10390898P | 1998-10-13 | 1998-10-13 | |
| US60/103,908 | 1998-10-13 | ||
| US09/347,613 US6593133B1 (en) | 1998-07-06 | 1999-07-02 | Neurotrophic factors |
| US199800904 | 1999-07-02 | ||
| US09/347,613 | 1999-07-02 | ||
| US199801265 | 1999-07-02 | ||
| US199801048 | 1999-07-02 | ||
| PCT/DK1999/000384 WO2000001815A2 (en) | 1998-07-06 | 1999-07-05 | Neurotrophic factors |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005161155A Division JP2005341968A (ja) | 1998-07-06 | 2005-06-01 | 神経栄養因子 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002519061A JP2002519061A (ja) | 2002-07-02 |
| JP2002519061A5 true JP2002519061A5 (enExample) | 2006-01-05 |
Family
ID=27561795
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000558205A Pending JP2002519061A (ja) | 1998-07-06 | 1999-07-05 | 神経栄養因子 |
| JP2005161155A Withdrawn JP2005341968A (ja) | 1998-07-06 | 2005-06-01 | 神経栄養因子 |
| JP2005326745A Withdrawn JP2006122053A (ja) | 1998-07-06 | 2005-11-10 | 神経栄養因子 |
| JP2007120282A Withdrawn JP2007252381A (ja) | 1998-07-06 | 2007-04-27 | 神経栄養因子 |
| JP2007307603A Pending JP2008133282A (ja) | 1998-07-06 | 2007-11-28 | 神経栄養因子 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005161155A Withdrawn JP2005341968A (ja) | 1998-07-06 | 2005-06-01 | 神経栄養因子 |
| JP2005326745A Withdrawn JP2006122053A (ja) | 1998-07-06 | 2005-11-10 | 神経栄養因子 |
| JP2007120282A Withdrawn JP2007252381A (ja) | 1998-07-06 | 2007-04-27 | 神経栄養因子 |
| JP2007307603A Pending JP2008133282A (ja) | 1998-07-06 | 2007-11-28 | 神経栄養因子 |
Country Status (18)
| Country | Link |
|---|---|
| US (6) | US6593133B1 (enExample) |
| EP (2) | EP2290079A3 (enExample) |
| JP (5) | JP2002519061A (enExample) |
| KR (1) | KR100743376B1 (enExample) |
| AT (1) | ATE522609T1 (enExample) |
| AU (1) | AU755114B2 (enExample) |
| CA (1) | CA2336218C (enExample) |
| CY (1) | CY1112101T1 (enExample) |
| DK (1) | DK1095140T3 (enExample) |
| EE (1) | EE05590B1 (enExample) |
| ES (1) | ES2373173T3 (enExample) |
| HU (1) | HU227870B1 (enExample) |
| IS (1) | IS2835B (enExample) |
| NZ (1) | NZ508994A (enExample) |
| PT (1) | PT1095140E (enExample) |
| SI (1) | SI1095140T1 (enExample) |
| TR (1) | TR200100056T2 (enExample) |
| WO (1) | WO2000001815A2 (enExample) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6593133B1 (en) * | 1998-07-06 | 2003-07-15 | Nsgene A/S | Neurotrophic factors |
| US20020055467A1 (en) * | 1998-07-06 | 2002-05-09 | Johansen Teit E. | Novel neurotrophic factors |
| HK1045528B (zh) * | 1998-07-14 | 2006-10-27 | 詹森药业有限公司 | 神经营养生长因子 |
| US7067473B1 (en) * | 1998-07-14 | 2006-06-27 | Janssen Pharmaceutica N.V. | Neurotrophic growth factor |
| US6284540B1 (en) | 1998-09-29 | 2001-09-04 | Washington University | Artemin, a novel neurotrophic factor |
| AU2354600A (en) * | 1998-12-09 | 2000-06-26 | Amgen, Inc. | Grnf4 a neurotrophic factor |
| WO2000054813A2 (en) * | 1999-03-15 | 2000-09-21 | Chiron Corporation | Use of recombinant gene delivery vectors for treating or preventing diseases of the eye |
| US6943153B1 (en) | 1999-03-15 | 2005-09-13 | The Regents Of The University Of California | Use of recombinant gene delivery vectors for treating or preventing diseases of the eye |
| EP1867719A3 (en) * | 1999-06-02 | 2008-03-19 | Genentech, Inc. | Methods and compositions for inhibiting neoplastic cell growth |
| NZ526610A (en) * | 2000-12-22 | 2009-08-28 | Genentech Inc | New use of artemin, a member of the GDNF ligand family |
| SK288123B6 (sk) * | 2001-02-01 | 2013-09-03 | Biogen Idec Ma Inc. | Polymer conjugates of neublastin and methods of using same |
| US7442370B2 (en) * | 2001-02-01 | 2008-10-28 | Biogen Idec Ma Inc. | Polymer conjugates of mutated neublastin |
| US7276580B2 (en) * | 2001-03-12 | 2007-10-02 | Biogen Idec Ma Inc. | Neurotrophic factors |
| AU2002250203B2 (en) * | 2001-03-28 | 2006-08-10 | Biogen Ma Inc. | Use of neublastin polypeptides for treating neuropathic pain |
| US20040077543A1 (en) * | 2001-03-28 | 2004-04-22 | Sah Dinah W. Y. | Treatment using neublastin polypeptides |
| US7115402B2 (en) * | 2002-07-09 | 2006-10-03 | Bristol-Myers Squibb Company | Polynucleotides encoding a novel testis-specific tubulin tyrosine-ligase-like protein, BGS42 |
| JP4571776B2 (ja) * | 2002-11-05 | 2010-10-27 | Ｊｘ日鉱日石エネルギー株式会社 | 潤滑油組成物 |
| ES2351215T3 (es) * | 2003-01-31 | 2011-02-01 | Biogen Idec Ma Inc. | Conjugados poliméricos de neublastina mutada. |
| ATE433759T1 (de) * | 2003-04-18 | 2009-07-15 | Biogen Idec Inc | Polymerkonjugiertes glycosiliertes neublastin |
| RU2005138368A (ru) | 2003-06-10 | 2006-07-27 | ЭнЭсДЖЕНЕ А/С (DK) | Улучшенная секреция нейбластина |
| US7598059B2 (en) | 2003-10-02 | 2009-10-06 | Biogen Idec Ma Inc. | Neublastin expression constructs |
| CN1897977A (zh) * | 2003-10-20 | 2007-01-17 | Ns基因公司 | 帕金森氏病的体内基因治疗 |
| JP4959566B2 (ja) * | 2004-08-19 | 2012-06-27 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | トランスホーミング増殖因子βファミリータンパク質の折りたたみ |
| EP2335713A3 (en) * | 2004-08-19 | 2011-11-02 | Biogen Idec MA Inc. | Neublastin variants |
| EP1919933A2 (en) * | 2005-08-16 | 2008-05-14 | Copenhagen University | Gdnf derived peptides |
| EP1937295A2 (en) * | 2005-10-11 | 2008-07-02 | NS Gene A/S | Treatment of retinopathies using gfr 3 agonists |
| TWI501774B (zh) | 2006-02-27 | 2015-10-01 | Biogen Idec Inc | 神經性病症之治療 |
| WO2007103182A2 (en) * | 2006-03-01 | 2007-09-13 | Biogen Idec Ma Inc. | Compostions and methods for administering gdnf ligand family proteins |
| JP5583005B2 (ja) * | 2007-05-01 | 2014-09-03 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | 血管新生を増大させるための組成物および方法 |
| CN101932602B (zh) * | 2007-06-27 | 2017-05-24 | 新加坡国立大学 | 用于Artemin及相关配体的多肽和多核苷酸，及其使用方法 |
| WO2009020964A2 (en) * | 2007-08-08 | 2009-02-12 | Biogen Idec Ma Inc. | Anti-neublastin antibodies and uses thereof |
| TWI702955B (zh) | 2012-05-15 | 2020-09-01 | 澳大利亞商艾佛蘭屈澳洲私營有限公司 | 使用腺相關病毒（ａａｖ）ｓｆｌｔ-１治療老年性黃斑部退化（ａｍｄ） |
| WO2014152511A1 (en) | 2013-03-15 | 2014-09-25 | The Jackson Laboratory | Methods for promoting wound healing and hair growth |
| CA2926645C (en) | 2013-10-14 | 2022-10-25 | Indiana University Research And Technology Corporation | Use of acamprosate to modulate erk 1/2 activation in animal models for fxs and asd and individuals diagnosed with fxs and asd |
| JP6689249B2 (ja) | 2014-03-17 | 2020-05-20 | アドヴェラム バイオテクノロジーズ， インコーポレイテッド | 錐体細胞における増強された遺伝子発現のための組成物および方法 |
| EP3256147B8 (en) * | 2015-01-18 | 2020-10-21 | Gloriana Therapeutics, Inc. | Therapeutic protein formulations |
| AU2016226289B2 (en) | 2015-03-02 | 2021-04-29 | Adverum Biotechnologies, Inc. | Compositions and methods for intravitreal delivery of polynucleotides to retinal cones |
| GB2545763A (en) | 2015-12-23 | 2017-06-28 | Adverum Biotechnologies Inc | Mutant viral capsid libraries and related systems and methods |
Family Cites Families (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4352883A (en) | 1979-03-28 | 1982-10-05 | Damon Corporation | Encapsulation of biological material |
| US4353888A (en) | 1980-12-23 | 1982-10-12 | Sefton Michael V | Encapsulation of live animal cells |
| US4407957A (en) | 1981-03-13 | 1983-10-04 | Damon Corporation | Reversible microencapsulation of a core material |
| US5525464A (en) | 1987-04-01 | 1996-06-11 | Hyseq, Inc. | Method of sequencing by hybridization of oligonucleotide probes |
| US4883666A (en) | 1987-04-29 | 1989-11-28 | Massachusetts Institute Of Technology | Controlled drug delivery system for treatment of neural disorders |
| US5158881A (en) | 1987-11-17 | 1992-10-27 | Brown University Research Foundation | Method and system for encapsulating cells in a tubular extrudate in separate cell compartments |
| US5283187A (en) | 1987-11-17 | 1994-02-01 | Brown University Research Foundation | Cell culture-containing tubular capsule produced by co-extrusion |
| DE3829752A1 (de) | 1988-09-01 | 1990-03-22 | Akzo Gmbh | Integrale asymmetrische polyaethersulfonmembran, verfahren zur herstellung und verwendung zur ultrafiltration und mikrofiltration |
| DE3829766A1 (de) | 1988-09-01 | 1990-03-22 | Akzo Gmbh | Verfahren zur herstellung von membranen |
| US5082670A (en) | 1988-12-15 | 1992-01-21 | The Regents Of The University Of California | Method of grafting genetically modified cells to treat defects, disease or damage or the central nervous system |
| US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| US5800992A (en) | 1989-06-07 | 1998-09-01 | Fodor; Stephen P.A. | Method of detecting nucleic acids |
| US5084350A (en) | 1990-02-16 | 1992-01-28 | The Royal Institution For The Advance Of Learning (Mcgill University) | Method for encapsulating biologically active material including cells |
| US5618531A (en) | 1990-10-19 | 1997-04-08 | New York University | Method for increasing the viability of cells which are administered to the brain or spinal cord |
| EP0585368B1 (en) | 1991-04-25 | 1997-08-06 | Brown University Research Foundation | Implantable biocompatible immunoisolatory vehicle for delivery of selected therapeutic products |
| ES2123001T5 (es) | 1991-06-27 | 2009-04-16 | Bristol-Myers Squibb Company | Receptor ctl4a, proteinas de fusion que lo contienen y sus usos. |
| ES2284226T3 (es) | 1991-07-02 | 2007-11-01 | Nektar Therapeutics | Dispositivo para proporcionar medicamentos en aerosol. |
| US5750376A (en) | 1991-07-08 | 1998-05-12 | Neurospheres Holdings Ltd. | In vitro growth and proliferation of genetically modified multipotent neural stem cells and their progeny |
| ATE275197T1 (de) | 1991-09-20 | 2004-09-15 | Amgen Inc | Glial neurotrophe faktor |
| US5968502A (en) | 1991-11-05 | 1999-10-19 | Transkaryotic Therapies, Inc. | Protein production and protein delivery |
| US5284350A (en) * | 1992-05-22 | 1994-02-08 | Medical Composite Technology | Foldable wheelchair and side frame assembly |
| US5785049A (en) | 1994-09-21 | 1998-07-28 | Inhale Therapeutic Systems | Method and apparatus for dispersion of dry powder medicaments |
| DK0679088T3 (da) | 1992-09-29 | 2002-10-28 | Inhale Therapeutic Syst | Pulmonal levering af aktive fragmenter af parathyreoideaea hormon |
| CA2092271C (en) | 1993-03-09 | 2009-10-13 | Eddie Reed | Use of g-csf for treating taxol side-effects |
| EP0802800B1 (en) | 1993-08-12 | 2002-06-12 | Neurotech S.A. | Biocompatible immunoisolatory capsules containing genetically altered cells for the delivery of biologically active molecules |
| DE4339605A1 (de) | 1993-11-20 | 1995-05-24 | Beiersdorf Ag | Desodorierende Wirkstoffkombinationen auf der Basis von alpha, omega-Alkandicarbonsäuren und Fettsäurepartialglyceriden |
| US5834029A (en) | 1994-07-20 | 1998-11-10 | Cytotherapeutics, Inc. | Nerve guidance channel containing bioartificial three-dimensional hydrogel extracellular matrix derivatized with cell adhesive peptide fragment |
| US5795716A (en) | 1994-10-21 | 1998-08-18 | Chee; Mark S. | Computer-aided visualization and analysis system for sequence evaluation |
| US5780014A (en) | 1995-04-14 | 1998-07-14 | Inhale Therapeutic Systems | Method and apparatus for pulmonary administration of dry powder alpha 1-antitrypsin |
| US5654007A (en) | 1995-06-07 | 1997-08-05 | Inhale Therapeutic Systems | Methods and system for processing dispersible fine powders |
| US5739307A (en) | 1995-08-28 | 1998-04-14 | Washington University | Polynucleotide encoding neurturin neurotrophic factor |
| US5733729A (en) | 1995-09-14 | 1998-03-31 | Affymetrix, Inc. | Computer-aided probability base calling for arrays of nucleic acid probes on chips |
| US5641749A (en) * | 1995-11-29 | 1997-06-24 | Amgen Inc. | Method for treating retinal ganglion cell injury using glial cell line-derived neurothrophic factor (GDNF) protein product |
| US6299895B1 (en) * | 1997-03-24 | 2001-10-09 | Neurotech S.A. | Device and method for treating ophthalmic diseases |
| US6878544B2 (en) * | 1996-04-19 | 2005-04-12 | Neurotech Sa | Retinal cell lines with extended life-span and their applications |
| DK0914339T3 (da) | 1996-05-08 | 2006-12-04 | Biogen Idec Inc | Ret ligand 3 (RetL3) til stimulering af neural og renal vækst |
| US5754524A (en) | 1996-08-30 | 1998-05-19 | Wark; Barry J. | Computerized method and system for analysis of an electrophoresis gel test |
| KR100195886B1 (ko) | 1996-11-01 | 1999-06-15 | 김상조 | 당뇨병 치료용 의약조성물 |
| EP0961830A1 (en) | 1997-01-29 | 1999-12-08 | Neurosearch A/S | EXPRESSION VECTORS AND METHODS FOR $i(IN VIVO) EXPRESSION OF THERAPEUTIC POLYPEPTIDES |
| US20020192209A1 (en) * | 1997-09-17 | 2002-12-19 | Genentech, Inc. | Methods and compositions for inhibiting neoplastic cell growth |
| US6593133B1 (en) * | 1998-07-06 | 2003-07-15 | Nsgene A/S | Neurotrophic factors |
| US20020055467A1 (en) * | 1998-07-06 | 2002-05-09 | Johansen Teit E. | Novel neurotrophic factors |
| HK1045528B (zh) | 1998-07-14 | 2006-10-27 | 詹森药业有限公司 | 神经营养生长因子 |
| AU778998B2 (en) * | 1998-09-22 | 2004-12-23 | University Of Maryland At Baltimore | Cystine knot growth factor mutants |
| US6284540B1 (en) | 1998-09-29 | 2001-09-04 | Washington University | Artemin, a novel neurotrophic factor |
| AU2354600A (en) * | 1998-12-09 | 2000-06-26 | Amgen, Inc. | Grnf4 a neurotrophic factor |
| EP1623989B1 (en) * | 1999-03-08 | 2007-06-13 | Genentech, Inc. | Compositions and methods for the diagnosis of tumours |
| US6361771B1 (en) * | 1999-04-06 | 2002-03-26 | Neurotech S.A. | ARPE-19 as a platform cell line for encapsulated cell-based delivery |
| ES2287020T3 (es) * | 1999-06-02 | 2007-12-16 | Genentech, Inc. | Procedimiento y composiciones para inhibir el crecimiento de celulas neoplasicas. |
| JP2001329126A (ja) | 2000-05-22 | 2001-11-27 | Bridgestone Corp | 硬化性組成物 |
| DE60138204D1 (de) * | 2000-09-12 | 2009-05-14 | Jfe Steel Corp | Ultra hochfestes kaltgewalztes stahlblech und sein herstellungsverfahren |
| US7276580B2 (en) * | 2001-03-12 | 2007-10-02 | Biogen Idec Ma Inc. | Neurotrophic factors |
| US20040077543A1 (en) * | 2001-03-28 | 2004-04-22 | Sah Dinah W. Y. | Treatment using neublastin polypeptides |
| US7598059B2 (en) * | 2003-10-02 | 2009-10-06 | Biogen Idec Ma Inc. | Neublastin expression constructs |
-
1999
- 1999-07-02 US US09/347,613 patent/US6593133B1/en not_active Expired - Lifetime
- 1999-07-05 PT PT99931023T patent/PT1095140E/pt unknown
- 1999-07-05 AU AU47693/99A patent/AU755114B2/en not_active Ceased
- 1999-07-05 JP JP2000558205A patent/JP2002519061A/ja active Pending
- 1999-07-05 CA CA2336218A patent/CA2336218C/en not_active Expired - Fee Related
- 1999-07-05 NZ NZ508994A patent/NZ508994A/en not_active IP Right Cessation
- 1999-07-05 HU HU0103758A patent/HU227870B1/hu not_active IP Right Cessation
- 1999-07-05 SI SI9931062T patent/SI1095140T1/sl unknown
- 1999-07-05 ES ES99931023T patent/ES2373173T3/es not_active Expired - Lifetime
- 1999-07-05 WO PCT/DK1999/000384 patent/WO2000001815A2/en not_active Ceased
- 1999-07-05 KR KR1020017000184A patent/KR100743376B1/ko not_active Expired - Fee Related
- 1999-07-05 EP EP10181304A patent/EP2290079A3/en not_active Withdrawn
- 1999-07-05 TR TR2001/00056T patent/TR200100056T2/xx unknown
- 1999-07-05 EE EEP200100008A patent/EE05590B1/xx not_active IP Right Cessation
- 1999-07-05 DK DK99931023.8T patent/DK1095140T3/da active
- 1999-07-05 AT AT99931023T patent/ATE522609T1/de active
- 1999-07-05 EP EP99931023A patent/EP1095140B1/en not_active Expired - Lifetime
-
2000
- 2000-09-15 US US09/662,183 patent/US6734284B1/en not_active Expired - Lifetime
- 2000-12-14 IS IS5769A patent/IS2835B/is unknown
-
2004
- 2004-03-22 US US10/806,793 patent/US20040230043A1/en not_active Abandoned
-
2005
- 2005-06-01 JP JP2005161155A patent/JP2005341968A/ja not_active Withdrawn
- 2005-11-10 JP JP2005326745A patent/JP2006122053A/ja not_active Withdrawn
-
2007
- 2007-04-27 JP JP2007120282A patent/JP2007252381A/ja not_active Withdrawn
- 2007-10-31 US US11/932,744 patent/US20080227703A1/en not_active Abandoned
- 2007-11-28 JP JP2007307603A patent/JP2008133282A/ja active Pending
-
2009
- 2009-10-27 US US12/606,602 patent/US20100234293A1/en not_active Abandoned
-
2011
- 2011-04-11 US US13/084,267 patent/US20120252726A1/en not_active Abandoned
- 2011-11-29 CY CY20111101173T patent/CY1112101T1/el unknown
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