JP2003515323A5 - - Google Patents
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- Publication number
- JP2003515323A5 JP2003515323A5 JP2001538975A JP2001538975A JP2003515323A5 JP 2003515323 A5 JP2003515323 A5 JP 2003515323A5 JP 2001538975 A JP2001538975 A JP 2001538975A JP 2001538975 A JP2001538975 A JP 2001538975A JP 2003515323 A5 JP2003515323 A5 JP 2003515323A5
- Authority
- JP
- Japan
- Prior art keywords
- canine
- polypeptide
- seq
- fragment
- derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 241000282465 Canis Species 0.000 claims 3
- 229920001184 polypeptide Polymers 0.000 claims 3
- 102000004196 processed proteins & peptides Human genes 0.000 claims 3
- 108090000765 processed proteins & peptides Proteins 0.000 claims 3
- 239000012634 fragment Substances 0.000 claims 2
- 239000002773 nucleotide Substances 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/GB1999/003859 WO2000029428A2 (en) | 1998-11-18 | 1999-11-18 | 5t4 tumour-associated antigen for use in tumour immunotherapy |
| GB99/03859 | 1999-11-18 | ||
| GB0003527A GB0003527D0 (en) | 2000-02-15 | 2000-02-15 | Antibodies |
| GB0003527.9 | 2000-02-15 | ||
| GB0005071A GB0005071D0 (en) | 2000-03-02 | 2000-03-02 | Antibodies |
| GB0005071.6 | 2000-03-02 | ||
| PCT/GB2000/004317 WO2001036486A2 (en) | 1999-11-18 | 2000-11-13 | Scfv antibodies against disease associated molecules |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003515323A JP2003515323A (ja) | 2003-05-07 |
| JP2003515323A5 true JP2003515323A5 (enExample) | 2007-12-20 |
Family
ID=27255534
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001538975A Pending JP2003515323A (ja) | 1999-11-18 | 2000-11-13 | 抗 体 |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US7074909B2 (enExample) |
| EP (1) | EP1242456B1 (enExample) |
| JP (1) | JP2003515323A (enExample) |
| CN (1) | CN1423660A (enExample) |
| AU (1) | AU1290001A (enExample) |
| CA (1) | CA2391925A1 (enExample) |
| WO (1) | WO2001036486A2 (enExample) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU747602B2 (en) | 1997-06-04 | 2002-05-16 | Oxford Biomedica (Uk) Limited | Vector |
| US7635687B2 (en) * | 1997-06-04 | 2009-12-22 | Oxford Biomedica (Uk) Limited | Vector system |
| US7276488B2 (en) | 1997-06-04 | 2007-10-02 | Oxford Biomedica (Uk) Limited | Vector system |
| AU1290001A (en) * | 1999-11-18 | 2001-05-30 | Oxford Biomedica (Uk) Limited | Antibodies |
| ATE411342T1 (de) * | 1999-11-18 | 2008-10-15 | Oxford Biomedica Ltd | Scfv antikörper gegen krankheiten-assoziierte moleküle |
| WO2002038612A2 (en) * | 2000-11-13 | 2002-05-16 | Oxford Biomedica (Uk) Limited | Canine and feline tumour-associated antigen 5t4 |
| SE0102327D0 (sv) * | 2001-06-28 | 2001-06-28 | Active Biotech Ab | A novel engineered superantigen for human therapy |
| GB0126378D0 (en) * | 2001-11-02 | 2002-01-02 | Oxford Biomedica Ltd | Antigen |
| MXPA05001933A (es) * | 2002-08-19 | 2005-04-28 | Genentech Inc | Composiciones y metodos para el diagnostico y tratamiento de tumores. |
| US6987270B2 (en) | 2003-05-07 | 2006-01-17 | General Electric Company | Method to account for event losses due to positron range in positron emission tomography and assay of positron-emitting isotopes |
| US8597911B2 (en) | 2003-06-11 | 2013-12-03 | Chugai Seiyaku Kabushiki Kaisha | Process for producing antibodies |
| TW200530269A (en) | 2003-12-12 | 2005-09-16 | Chugai Pharmaceutical Co Ltd | Anti-Mpl antibodies |
| WO2006017325A2 (en) * | 2004-07-13 | 2006-02-16 | Cell Genesys, Inc. | Aav vector compositions and methods for enhanced expression of immunoglobulins the same |
| TW200616662A (en) * | 2004-09-10 | 2006-06-01 | Wyeth Corp | Humanized anti-5t4 antibodies and anti-5t4 antibody/calicheamicin conjugates |
| JP5620626B2 (ja) | 2005-03-31 | 2014-11-05 | 中外製薬株式会社 | 会合制御によるポリペプチド製造方法 |
| US9493569B2 (en) | 2005-03-31 | 2016-11-15 | Chugai Seiyaku Kabushiki Kaisha | Structural isomers of sc(Fv)2 |
| CA2611726C (en) * | 2005-06-10 | 2017-07-11 | Chugai Seiyaku Kabushiki Kaisha | Pharmaceutical compositions containing sc(fv)2 |
| EP1908482B1 (en) | 2005-06-10 | 2017-09-06 | Chugai Seiyaku Kabushiki Kaisha | Stabilizer for protein preparation comprising meglumine and use thereof |
| KR101360671B1 (ko) | 2005-06-10 | 2014-02-07 | 추가이 세이야쿠 가부시키가이샤 | sc(Fv)2를 함유하는 의약조성물 |
| GB0519303D0 (en) * | 2005-09-21 | 2005-11-02 | Oxford Biomedica Ltd | Chemo-immunotherapy method |
| EP2009101B1 (en) | 2006-03-31 | 2017-10-25 | Chugai Seiyaku Kabushiki Kaisha | Antibody modification method for purifying bispecific antibody |
| AU2007308145A1 (en) | 2006-10-12 | 2008-04-17 | Wyeth | Modification of ionic strength in antibody-solutions to reduce opalescence/aggregates |
| US8097422B2 (en) | 2007-06-20 | 2012-01-17 | Salk Institute For Biological Studies | Kir channel modulators |
| KR100949791B1 (ko) * | 2007-12-18 | 2010-03-30 | 이동기 | 오프-타겟 효과를 최소화하고 RNAi 기구를 포화시키지않는 신규한 siRNA 구조 및 그 용도 |
| US8642274B2 (en) * | 2008-07-15 | 2014-02-04 | Oxford Biomedica, Inc. | Immunotherapeutic method |
| US8940501B2 (en) | 2009-01-30 | 2015-01-27 | Whitehead Institute For Biomedical Research | Methods for ligation and uses thereof |
| JP2011026294A (ja) * | 2009-06-26 | 2011-02-10 | Canon Inc | 化合物 |
| WO2013041687A1 (en) * | 2011-09-23 | 2013-03-28 | Amgen Research (Munich) Gmbh | Bispecific binding molecules for 5t4 and cd3 |
| JP6254951B2 (ja) | 2012-01-24 | 2017-12-27 | ファイザー・インク | 哺乳類の対象における5t4陽性循環腫瘍細胞を検出するための方法および5t4陽性がんの診断の方法 |
| EP3010939A2 (en) | 2013-06-17 | 2016-04-27 | Asana BioSciences, LLC | 5t4-targeted immunofusion molecule and methods |
| ES2881306T3 (es) | 2013-09-27 | 2021-11-29 | Chugai Pharmaceutical Co Ltd | Método para la producción de heteromultímeros de polipéptidos |
| PL3054992T3 (pl) | 2013-10-11 | 2020-01-31 | Asana Biosciences, Llc | Koniugaty białko-polimer-lek |
| ES2726850T3 (es) | 2013-10-11 | 2019-10-09 | Mersana Therapeutics Inc | Conjugados de proteína-polímero-fármaco |
| WO2015133484A1 (ja) * | 2014-03-04 | 2015-09-11 | 国立大学法人徳島大学 | 腎臓疾患に関するマーカー及びその利用 |
| WO2016120331A1 (de) | 2015-01-28 | 2016-08-04 | Karl Sebastian Lang | Agonistische anti-cd66cd66 antikörper für die antiviralen therapie |
| JP7219005B2 (ja) | 2015-12-28 | 2023-02-07 | 中外製薬株式会社 | Fc領域含有ポリペプチドの精製を効率化するための方法 |
| CN106749656B (zh) * | 2016-11-11 | 2018-04-13 | 郑州师范学院 | 一种抗小鼠RCN3蛋白单克隆ScFv抗体及其淘选方法 |
| US11135307B2 (en) | 2016-11-23 | 2021-10-05 | Mersana Therapeutics, Inc. | Peptide-containing linkers for antibody-drug conjugates |
| KR20230166145A (ko) | 2017-03-15 | 2023-12-06 | 옥스포드 바이오메디카(유케이) 리미티드 | 방법 |
| EP3704151A4 (en) | 2017-11-01 | 2021-07-28 | NantBio, Inc. | EMT PATH BLOCKING IINTERLEUKIN 8 AND CONTROLLING CARCINOUS STEM CELLS |
| EP3717021A1 (en) | 2017-11-27 | 2020-10-07 | Mersana Therapeutics, Inc. | Pyrrolobenzodiazepine antibody conjugates |
| EP3727463A1 (en) | 2017-12-21 | 2020-10-28 | Mersana Therapeutics, Inc. | Pyrrolobenzodiazepine antibody conjugates |
| EP3765493A2 (en) | 2018-03-12 | 2021-01-20 | Genmab A/S | Antibodies |
| AU2019369340A1 (en) | 2018-10-29 | 2021-05-20 | Mersana Therapeutics, Inc. | Cysteine engineered antibody-drug conjugates with peptide-containing linkers |
| AR132178A1 (es) | 2023-03-22 | 2025-06-04 | Salubris Biotherapeutics Inc | Dominios de unión al antígeno anti-5t4, conjugados anticuerpo-fármaco, y métodos de uso de los mismos |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3481051A (en) * | 1969-02-06 | 1969-12-02 | Paramount Packaging Corp | Heating apparatus |
| US4009778A (en) * | 1975-11-04 | 1977-03-01 | The Kartridg Pak Co. | Dual compartment package and method for making same |
| US4267768A (en) * | 1976-09-20 | 1981-05-19 | David M. Cieslak | Process for fabricating a reclosable bag |
| US4997913A (en) | 1986-06-30 | 1991-03-05 | Oncogen | pH-sensitive immunoconjugates and methods for their use in tumor therapy |
| EP0403559A1 (en) * | 1988-03-04 | 1990-12-27 | Cancer Research Campaign Technology Limited | Improvements relating to antigens |
| US5591624A (en) | 1988-03-21 | 1997-01-07 | Chiron Viagene, Inc. | Retroviral packaging cell lines |
| US5060146A (en) | 1988-04-08 | 1991-10-22 | International Business Machines Corporation | Multilingual indexing system for alphabetical lysorting by comparing character weights and ascii codes |
| JPH04500308A (ja) | 1989-05-17 | 1992-01-23 | リサーチ・コーポレーション・テクノロジーズ・インコーポレーテッド | 組換え型生成物のレトロウィルス媒介分泌 |
| GB9109645D0 (en) | 1991-05-03 | 1991-06-26 | Celltech Ltd | Recombinant antibodies |
| EP0590058B1 (en) | 1991-06-14 | 2003-11-26 | Genentech, Inc. | HUMANIZED Heregulin ANTIBODy |
| US5776427A (en) * | 1992-03-05 | 1998-07-07 | Board Of Regents, The University Of Texas System | Methods for targeting the vasculature of solid tumors |
| GB9223816D0 (en) | 1992-11-13 | 1993-01-06 | Medical Res Council | Heat shock proteins and the treatment of tumours |
| US5582826A (en) * | 1993-04-21 | 1996-12-10 | Ajinomoto Co., Inc. | Monoclonal antibodies which bind the gamma chain of human interleukin-2 receptor |
| ATE236258T1 (de) * | 1993-05-12 | 2003-04-15 | Xoma Corp | Gelonin und einen antikörper entahltende immuntoxine |
| GB9324807D0 (en) * | 1993-12-03 | 1994-01-19 | Cancer Res Campaign Tech | Tumour antibody |
| US5559099A (en) | 1994-09-08 | 1996-09-24 | Genvec, Inc. | Penton base protein and methods of using same |
| EP0706799B1 (en) | 1994-09-16 | 2001-11-14 | MERCK PATENT GmbH | Immunoconjugates II |
| GB9423085D0 (en) | 1994-11-16 | 1995-01-04 | Stringer Bradley M J | Targeted T lymphocytes |
| US5824762A (en) * | 1994-11-28 | 1998-10-20 | Dow Corning Toray Silicone Co., Ltd. | Organopolysiloxane and method for the preparation of the same |
| WO1996030504A1 (en) | 1995-03-24 | 1996-10-03 | Genetic Therapy, Inc. | Modified viral envelope polypeptide |
| FR2732348B1 (fr) | 1995-03-31 | 1997-04-30 | Rhone Poulenc Rorer Sa | Systeme d'expression conditionnel |
| US5637462A (en) * | 1995-04-19 | 1997-06-10 | Incyte Pharmaceuticals, Inc. | Cathepsin C homolog |
| US20030026789A1 (en) | 1995-05-03 | 2003-02-06 | Richard J. Gregory | Gene therapy using replication competent targeted adenoviral vectors |
| ES2252744T3 (es) * | 1995-06-06 | 2006-05-16 | Human Genome Sciences, Inc. | Gen y proteina especificos del colon. |
| DE19531346A1 (de) * | 1995-08-25 | 1997-02-27 | Gsf Forschungszentrum Umwelt | Arzneimittel zur Immuntherapie, enthaltend Antikörper, die spezifisch das MHCII-Antigen eines zu behandelnden Patienten erkennen |
| AU7719596A (en) | 1995-11-07 | 1997-05-29 | Baylor College Of Medicine | Adenovirus-mediated production of bioactive proteins by mammalian cells and animals |
| SE9601245D0 (sv) | 1996-03-29 | 1996-03-29 | Pharmacia Ab | Chimeric superantigens and their use |
| TW517061B (en) | 1996-03-29 | 2003-01-11 | Pharmacia & Amp Upjohn Ab | Modified/chimeric superantigens and their use |
| ES2279539T3 (es) * | 1996-05-04 | 2007-08-16 | Astrazeneca Ab | Anticuerpo monoclonal anti-cea, conjugados que comprenden dicho anticuerpo, y su uso terapeutico en un sistema adept. |
| JP4175678B2 (ja) * | 1996-06-07 | 2008-11-05 | 武田薬品工業株式会社 | 新規ペプチド、その製造法および用途 |
| WO1998012227A1 (en) * | 1996-09-19 | 1998-03-26 | Diagnocure Inc. | Recombinant single chain antibodies directed against the gp54 cancer marker, composition comprising same and use thereof |
| US6348584B1 (en) | 1996-10-17 | 2002-02-19 | John Edward Hodgson | Fibronectin binding protein compounds |
| AU747602B2 (en) | 1997-06-04 | 2002-05-16 | Oxford Biomedica (Uk) Limited | Vector |
| JPH1156368A (ja) * | 1997-08-27 | 1999-03-02 | Nippon Seibutsu Kagaku Kenkyusho | 猫トロンボポエチンの活性を有する因子 |
| EP1068338A2 (en) * | 1998-03-06 | 2001-01-17 | Oxford Biomedica (UK) Limited | Enhanced prodrug activation |
| CN1298851C (zh) * | 1998-11-18 | 2007-02-07 | 牛津生物医学(英国)有限公司 | 多肽 |
| AU1290001A (en) | 1999-11-18 | 2001-05-30 | Oxford Biomedica (Uk) Limited | Antibodies |
| ATE411342T1 (de) * | 1999-11-18 | 2008-10-15 | Oxford Biomedica Ltd | Scfv antikörper gegen krankheiten-assoziierte moleküle |
-
2000
- 2000-11-13 AU AU12900/01A patent/AU1290001A/en not_active Abandoned
- 2000-11-13 WO PCT/GB2000/004317 patent/WO2001036486A2/en not_active Ceased
- 2000-11-13 JP JP2001538975A patent/JP2003515323A/ja active Pending
- 2000-11-13 EP EP00974682A patent/EP1242456B1/en not_active Expired - Lifetime
- 2000-11-13 CA CA002391925A patent/CA2391925A1/en not_active Abandoned
- 2000-11-13 CN CN00818416A patent/CN1423660A/zh active Pending
-
2001
- 2001-11-02 US US10/016,686 patent/US7074909B2/en not_active Expired - Lifetime
-
2006
- 2006-04-26 US US11/333,859 patent/US7514546B2/en not_active Expired - Lifetime
-
2008
- 2008-05-15 US US12/121,621 patent/US20100040539A1/en not_active Abandoned
-
2010
- 2010-07-28 US US12/845,380 patent/US20110052577A1/en not_active Abandoned
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