JP2003515323A - 抗 体 - Google Patents
抗 体Info
- Publication number
- JP2003515323A JP2003515323A JP2001538975A JP2001538975A JP2003515323A JP 2003515323 A JP2003515323 A JP 2003515323A JP 2001538975 A JP2001538975 A JP 2001538975A JP 2001538975 A JP2001538975 A JP 2001538975A JP 2003515323 A JP2003515323 A JP 2003515323A
- Authority
- JP
- Japan
- Prior art keywords
- scfv
- dam
- nucleotide sequence
- cells
- scfv antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- Cell Biology (AREA)
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- AIDS & HIV (AREA)
- Oncology (AREA)
- Veterinary Medicine (AREA)
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- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB99/03859 | 1999-11-18 | ||
| PCT/GB1999/003859 WO2000029428A2 (en) | 1998-11-18 | 1999-11-18 | 5t4 tumour-associated antigen for use in tumour immunotherapy |
| GB0003527A GB0003527D0 (en) | 2000-02-15 | 2000-02-15 | Antibodies |
| GB0003527.9 | 2000-02-15 | ||
| GB0005071.6 | 2000-03-02 | ||
| GB0005071A GB0005071D0 (en) | 2000-03-02 | 2000-03-02 | Antibodies |
| PCT/GB2000/004317 WO2001036486A2 (en) | 1999-11-18 | 2000-11-13 | Scfv antibodies against disease associated molecules |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003515323A true JP2003515323A (ja) | 2003-05-07 |
| JP2003515323A5 JP2003515323A5 (enExample) | 2007-12-20 |
Family
ID=27255534
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001538975A Pending JP2003515323A (ja) | 1999-11-18 | 2000-11-13 | 抗 体 |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US7074909B2 (enExample) |
| EP (1) | EP1242456B1 (enExample) |
| JP (1) | JP2003515323A (enExample) |
| CN (1) | CN1423660A (enExample) |
| AU (1) | AU1290001A (enExample) |
| CA (1) | CA2391925A1 (enExample) |
| WO (1) | WO2001036486A2 (enExample) |
Cited By (12)
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| WO2006132352A1 (ja) * | 2005-06-10 | 2006-12-14 | Chugai Seiyaku Kabushiki Kaisha | sc(Fv)2を含有する医薬組成物 |
| JP2008506389A (ja) * | 2004-07-13 | 2008-03-06 | セル ジェネシス インコーポレイテッド | Ａａｖベクター組成物および免疫グロブリンの発現の増強のための方法ならびにその使用方法 |
| US7993642B2 (en) | 2003-12-12 | 2011-08-09 | Chugai Seiyaku Kabushiki Kaisha | Anti-MPL antibodies |
| US8597911B2 (en) | 2003-06-11 | 2013-12-03 | Chugai Seiyaku Kabushiki Kaisha | Process for producing antibodies |
| US8945543B2 (en) | 2005-06-10 | 2015-02-03 | Chugai Seiyaku Kabushiki Kaisha | Stabilizer for protein preparation comprising meglumine and use thereof |
| WO2015133484A1 (ja) * | 2014-03-04 | 2015-09-11 | 国立大学法人徳島大学 | 腎臓疾患に関するマーカー及びその利用 |
| US9493569B2 (en) | 2005-03-31 | 2016-11-15 | Chugai Seiyaku Kabushiki Kaisha | Structural isomers of sc(Fv)2 |
| US9670269B2 (en) | 2006-03-31 | 2017-06-06 | Chugai Seiyaku Kabushiki Kaisha | Methods of modifying antibodies for purification of bispecific antibodies |
| US9777066B2 (en) | 2005-06-10 | 2017-10-03 | Chugai Seiyaku Kabushiki Kaisha | Pharmaceutical compositions containing sc(Fv)2 |
| US10011858B2 (en) | 2005-03-31 | 2018-07-03 | Chugai Seiyaku Kabushiki Kaisha | Methods for producing polypeptides by regulating polypeptide association |
| US11124576B2 (en) | 2013-09-27 | 2021-09-21 | Chungai Seiyaku Kabushiki Kaisha | Method for producing polypeptide heteromultimer |
| US11649262B2 (en) | 2015-12-28 | 2023-05-16 | Chugai Seiyaku Kabushiki Kaisha | Method for promoting efficiency of purification of Fc region-containing polypeptide |
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| CA2292760A1 (en) | 1997-06-04 | 1998-12-10 | Oxford Biomedica (Uk) Limited | Vector |
| US7276488B2 (en) | 1997-06-04 | 2007-10-02 | Oxford Biomedica (Uk) Limited | Vector system |
| WO2001036486A2 (en) | 1999-11-18 | 2001-05-25 | Oxford Biomedica (Uk) Limited | Scfv antibodies against disease associated molecules |
| US7635687B2 (en) * | 1997-06-04 | 2009-12-22 | Oxford Biomedica (Uk) Limited | Vector system |
| EP2161286A1 (en) * | 1999-11-18 | 2010-03-10 | Oxford Biomedica (UK) Limited | Antibodies |
| WO2002038612A2 (en) * | 2000-11-13 | 2002-05-16 | Oxford Biomedica (Uk) Limited | Canine and feline tumour-associated antigen 5t4 |
| SE0102327D0 (sv) | 2001-06-28 | 2001-06-28 | Active Biotech Ab | A novel engineered superantigen for human therapy |
| GB0126378D0 (en) * | 2001-11-02 | 2002-01-02 | Oxford Biomedica Ltd | Antigen |
| KR20050048615A (ko) * | 2002-08-19 | 2005-05-24 | 제넨테크, 인크. | 종양의 진단 및 치료를 위한 조성물 및 방법 |
| US6987270B2 (en) | 2003-05-07 | 2006-01-17 | General Electric Company | Method to account for event losses due to positron range in positron emission tomography and assay of positron-emitting isotopes |
| GT200500255A (es) * | 2004-09-10 | 2006-04-10 | Anticuerpos anti-5ta humanizados y conjugados anticuerpo anti-5ta/calicheamicina | |
| GB0519303D0 (en) | 2005-09-21 | 2005-11-02 | Oxford Biomedica Ltd | Chemo-immunotherapy method |
| RU2009111138A (ru) | 2006-10-12 | 2010-11-20 | Вайет (Us) | Способы и композиции с уменьшенной опалесценцией |
| US8097422B2 (en) | 2007-06-20 | 2012-01-17 | Salk Institute For Biological Studies | Kir channel modulators |
| KR100949791B1 (ko) * | 2007-12-18 | 2010-03-30 | 이동기 | 오프-타겟 효과를 최소화하고 ＲＮＡｉ 기구를 포화시키지않는 신규한 ｓｉＲＮＡ 구조 및 그 용도 |
| WO2010007365A1 (en) * | 2008-07-15 | 2010-01-21 | Oxford Biomedica (Uk) Ltd | Immunotherapeutic method |
| WO2010087994A2 (en) | 2009-01-30 | 2010-08-05 | Whitehead Institute For Biomedical Research | Methods for ligation and uses thereof |
| JP2011026294A (ja) * | 2009-06-26 | 2011-02-10 | Canon Inc | 化合物 |
| AU2012311492A1 (en) * | 2011-09-23 | 2014-03-06 | Amgen Research (Munich) Gmbh | Bispecific binding molecules for 5T4 and CD3 |
| ES2724232T3 (es) | 2012-01-24 | 2019-09-09 | Pfizer | Procedimientos de detección de células tumorales circulantes positivas para 5T4 y procedimientos de diagnóstico de cáncer positivo para 5T4 en un sujeto mamífero |
| EP3010939A2 (en) | 2013-06-17 | 2016-04-27 | Asana BioSciences, LLC | 5t4-targeted immunofusion molecule and methods |
| WO2015054669A1 (en) * | 2013-10-11 | 2015-04-16 | Asana Biosciences, Llc | Protein-polymer-drug conjugates |
| EA032231B1 (ru) | 2013-10-11 | 2019-04-30 | Мерсана Терапьютикс, Инк. | Конъюгаты белок-полимер-лекарственное средство |
| WO2016120331A1 (de) | 2015-01-28 | 2016-08-04 | Karl Sebastian Lang | Agonistische anti-cd66cd66 antikörper für die antiviralen therapie |
| CN106749656B (zh) * | 2016-11-11 | 2018-04-13 | 郑州师范学院 | 一种抗小鼠RCN3蛋白单克隆ScFv抗体及其淘选方法 |
| US11135307B2 (en) | 2016-11-23 | 2021-10-05 | Mersana Therapeutics, Inc. | Peptide-containing linkers for antibody-drug conjugates |
| WO2018167486A1 (en) | 2017-03-15 | 2018-09-20 | Oxford Biomedica (Uk) Limited | Method |
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Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8597911B2 (en) | 2003-06-11 | 2013-12-03 | Chugai Seiyaku Kabushiki Kaisha | Process for producing antibodies |
| US7993642B2 (en) | 2003-12-12 | 2011-08-09 | Chugai Seiyaku Kabushiki Kaisha | Anti-MPL antibodies |
| US8008073B2 (en) | 2003-12-12 | 2011-08-30 | Chugai Seiyaku Kabushiki Kaisha | Anti-Mpl antibodies |
| JP2008506389A (ja) * | 2004-07-13 | 2008-03-06 | セル ジェネシス インコーポレイテッド | Ａａｖベクター組成物および免疫グロブリンの発現の増強のための方法ならびにその使用方法 |
| US9493569B2 (en) | 2005-03-31 | 2016-11-15 | Chugai Seiyaku Kabushiki Kaisha | Structural isomers of sc(Fv)2 |
| US11168344B2 (en) | 2005-03-31 | 2021-11-09 | Chugai Seiyaku Kabushiki Kaisha | Methods for producing polypeptides by regulating polypeptide association |
| US10011858B2 (en) | 2005-03-31 | 2018-07-03 | Chugai Seiyaku Kabushiki Kaisha | Methods for producing polypeptides by regulating polypeptide association |
| US9777066B2 (en) | 2005-06-10 | 2017-10-03 | Chugai Seiyaku Kabushiki Kaisha | Pharmaceutical compositions containing sc(Fv)2 |
| WO2006132352A1 (ja) * | 2005-06-10 | 2006-12-14 | Chugai Seiyaku Kabushiki Kaisha | sc(Fv)2を含有する医薬組成物 |
| US8945543B2 (en) | 2005-06-10 | 2015-02-03 | Chugai Seiyaku Kabushiki Kaisha | Stabilizer for protein preparation comprising meglumine and use thereof |
| US9670269B2 (en) | 2006-03-31 | 2017-06-06 | Chugai Seiyaku Kabushiki Kaisha | Methods of modifying antibodies for purification of bispecific antibodies |
| US10934344B2 (en) | 2006-03-31 | 2021-03-02 | Chugai Seiyaku Kabushiki Kaisha | Methods of modifying antibodies for purification of bispecific antibodies |
| US11124576B2 (en) | 2013-09-27 | 2021-09-21 | Chungai Seiyaku Kabushiki Kaisha | Method for producing polypeptide heteromultimer |
| WO2015133484A1 (ja) * | 2014-03-04 | 2015-09-11 | 国立大学法人徳島大学 | 腎臓疾患に関するマーカー及びその利用 |
| US11649262B2 (en) | 2015-12-28 | 2023-05-16 | Chugai Seiyaku Kabushiki Kaisha | Method for promoting efficiency of purification of Fc region-containing polypeptide |
Also Published As
| Publication number | Publication date |
|---|---|
| AU1290001A (en) | 2001-05-30 |
| WO2001036486A2 (en) | 2001-05-25 |
| US20100040539A1 (en) | 2010-02-18 |
| US20070259400A1 (en) | 2007-11-08 |
| US20110052577A1 (en) | 2011-03-03 |
| EP1242456B1 (en) | 2008-10-15 |
| CA2391925A1 (en) | 2001-05-25 |
| WO2001036486A3 (en) | 2002-05-10 |
| EP1242456A2 (en) | 2002-09-25 |
| US20060014222A1 (en) | 2006-01-19 |
| US7514546B2 (en) | 2009-04-07 |
| CN1423660A (zh) | 2003-06-11 |
| US7074909B2 (en) | 2006-07-11 |
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