DE60040555D1 - Küle - Google Patents
KüleInfo
- Publication number
- DE60040555D1 DE60040555D1 DE60040555T DE60040555T DE60040555D1 DE 60040555 D1 DE60040555 D1 DE 60040555D1 DE 60040555 T DE60040555 T DE 60040555T DE 60040555 T DE60040555 T DE 60040555T DE 60040555 D1 DE60040555 D1 DE 60040555D1
- Authority
- DE
- Germany
- Prior art keywords
- scfv
- dam
- cules
- disease
- applicatrions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2318/00—Antibody mimetics or scaffolds
- C07K2318/10—Immunoglobulin or domain(s) thereof as scaffolds for inserted non-Ig peptide sequences, e.g. for vaccination purposes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Conductive Materials (AREA)
- Superconductors And Manufacturing Methods Therefor (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/GB1999/003859 WO2000029428A2 (en) | 1998-11-18 | 1999-11-18 | 5t4 tumour-associated antigen for use in tumour immunotherapy |
GB0003527A GB0003527D0 (en) | 2000-02-15 | 2000-02-15 | Antibodies |
GB0005071A GB0005071D0 (en) | 2000-03-02 | 2000-03-02 | Antibodies |
PCT/GB2000/004317 WO2001036486A2 (en) | 1999-11-18 | 2000-11-13 | Scfv antibodies against disease associated molecules |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60040555D1 true DE60040555D1 (de) | 2008-11-27 |
Family
ID=38233183
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60040555T Expired - Lifetime DE60040555D1 (de) | 1999-11-18 | 2000-11-13 | Küle |
Country Status (5)
Country | Link |
---|---|
US (1) | US20070161080A1 (de) |
EP (1) | EP2161286A1 (de) |
KR (1) | KR20020049054A (de) |
AT (1) | ATE411342T1 (de) |
DE (1) | DE60040555D1 (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7276488B2 (en) * | 1997-06-04 | 2007-10-02 | Oxford Biomedica (Uk) Limited | Vector system |
NZ500633A (en) * | 1997-06-04 | 2002-10-25 | Oxford Biomedica Ltd | Vector |
JP2003515323A (ja) * | 1999-11-18 | 2003-05-07 | オックスフォード バイオメディカ(ユーケイ)リミテッド | 抗 体 |
GB0126378D0 (en) * | 2001-11-02 | 2002-01-02 | Oxford Biomedica Ltd | Antigen |
ES2910365T3 (es) * | 2016-04-22 | 2022-05-12 | Alligator Bioscience Ab | Nuevos polipéptidos biespecíficos contra CD137 |
EP3655439A1 (de) | 2017-07-20 | 2020-05-27 | Aptevo Research and Development LLC | An 5t4 und 4-1bb bindende antigenbindende proteine und zugehörige zusammensetzungen und verfahren |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ500633A (en) * | 1997-06-04 | 2002-10-25 | Oxford Biomedica Ltd | Vector |
EP1036091B2 (de) * | 1998-11-18 | 2008-03-26 | Oxford Biomedica (UK) Limited | Verwendung vom krebs-assoziierten antigen 5t4 zur immuntherapie |
JP2003515323A (ja) * | 1999-11-18 | 2003-05-07 | オックスフォード バイオメディカ(ユーケイ)リミテッド | 抗 体 |
-
2000
- 2000-11-13 AT AT00974682T patent/ATE411342T1/de not_active IP Right Cessation
- 2000-11-13 KR KR1020027006362A patent/KR20020049054A/ko not_active Application Discontinuation
- 2000-11-13 EP EP08015458A patent/EP2161286A1/de not_active Withdrawn
- 2000-11-13 DE DE60040555T patent/DE60040555D1/de not_active Expired - Lifetime
-
2006
- 2006-07-07 US US11/482,552 patent/US20070161080A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
KR20020049054A (ko) | 2002-06-24 |
US20070161080A1 (en) | 2007-07-12 |
ATE411342T1 (de) | 2008-10-15 |
EP2161286A1 (de) | 2010-03-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |