DE3177213D1
(de)
|
1980-04-03 |
1990-10-18 |
Biogen Inc |
Dns-sequenzen, rekombinante dns-molekuele und verfahren zur herstellung von dem menschlichen fibroblast-interferon.
|
IT1185503B
(it)
*
|
1984-01-11 |
1987-11-12 |
Univ New York |
Cloni di odna di eritropietina umana
|
JPS62501010A
(ja)
|
1984-12-04 |
1987-04-23 |
ジェネティックス・インスチチュ−ト・インコ−ポレ−テッド |
エリトロポエチンの生産方法
|
IL77081A
(en)
*
|
1984-12-04 |
1999-10-28 |
Genetics Inst |
AND sequence encoding human erythropoietin, a process for its preparation and a pharmacological preparation of human erythropoietin
|
US4677195A
(en)
*
|
1985-01-11 |
1987-06-30 |
Genetics Institute, Inc. |
Method for the purification of erythropoietin and erythropoietin compositions
|
US4745099A
(en)
*
|
1985-02-06 |
1988-05-17 |
Chugai Seiyaku Kabushiki Kaisha |
Pharmaceutical composition for the treatment of the anemia of malignant tumors
|
US4732889A
(en)
*
|
1985-02-06 |
1988-03-22 |
Chugai Seiyaku Kabushiki Kaisha |
Pharmaceutical composition for the treatment of the anemia of rheumatoid arthritis
|
GB2177914B
(en)
*
|
1985-06-04 |
1989-10-25 |
Chugai Pharmaceutical Co Ltd |
A pharmaceutical composition containing human erythropoietin and a surface active agent for nasal administration for the treatment of anemia
|
IL79176A
(en)
*
|
1985-06-20 |
1992-06-21 |
Kirin Amgen Inc |
Process for the recovery of erythropoietin from a fluid
|
US4810643A
(en)
*
|
1985-08-23 |
1989-03-07 |
Kirin- Amgen Inc. |
Production of pluripotent granulocyte colony-stimulating factor
|
US6004548A
(en)
|
1985-08-23 |
1999-12-21 |
Amgen, Inc. |
Analogs of pluripotent granulocyte colony-stimulating factor
|
JPS63500636A
(ja)
*
|
1985-08-23 |
1988-03-10 |
麒麟麦酒株式会社 |
多分化能性顆粒球コロニー刺激因子をコードするdna
|
US4935350A
(en)
*
|
1985-11-18 |
1990-06-19 |
Amgen |
Materials and methods for controlling plasmid copy number and stability
|
JPS62171696A
(ja)
*
|
1986-01-23 |
1987-07-28 |
Sumitomo Chem Co Ltd |
ヒトエリスロポエチンの製造方法
|
DE3789678T2
(de)
*
|
1986-02-27 |
1994-08-11 |
Snow Brand Milk Prod Co Ltd |
Herstellung von erythropoietinproduzierenden Zellen und Verfahren zur Herstellung von Erythropoietin mit Verwendung dieser Zellen.
|
DK173067B1
(da)
|
1986-06-27 |
1999-12-13 |
Univ Washington |
Humant erythropoietin-gen, fremgangsmåde til ekspression deraf i transficerede cellelinier, de transficerede cellelinier sa
|
GR871029B
(en)
|
1986-07-14 |
1987-11-02 |
Genetics Inst |
Novel osteoinductive factors
|
US4954437A
(en)
*
|
1986-09-15 |
1990-09-04 |
Integrated Genetics, Inc. |
Cell encoding recombinant human erythropoietin
|
US5013718A
(en)
*
|
1986-11-21 |
1991-05-07 |
Amgen, Inc. |
Method for treating iron overload using EPO
|
WO1988005466A2
(fr)
*
|
1987-01-15 |
1988-07-28 |
Codon |
Vecteurs d'expression eukaryotique de genes en tandem
|
US4835260A
(en)
*
|
1987-03-20 |
1989-05-30 |
Genetics Institute, Inc. |
Erythropoietin composition
|
JP2791418B2
(ja)
|
1987-12-02 |
1998-08-27 |
株式会社ミドリ十字 |
異種蛋白質の製造方法、組換えdna、形質転換体
|
DE3923963A1
(de)
*
|
1989-07-20 |
1991-01-31 |
Behringwerke Ag |
Muteine des menschlichen erythropoetins, ihre herstellung und ihre verwendung
|
DE3924746A1
(de)
*
|
1989-07-26 |
1991-01-31 |
Behringwerke Ag |
Erythropoietin (epo)-peptide und dagegen gerichtete antikoerper
|
US6932968B1
(en)
|
1989-07-26 |
2005-08-23 |
Dade Behring Marburg Gmbh |
Erythropoietin (EPO) peptides and antibodies directed against these
|
KR100263845B1
(ko)
*
|
1989-10-13 |
2000-08-16 |
스튜어트 엘.왓트 |
에리트로포이에틴 동형체와 그의 제조방법 및 그를 포함하는제약학적 조성물
|
US7217689B1
(en)
|
1989-10-13 |
2007-05-15 |
Amgen Inc. |
Glycosylation analogs of erythropoietin
|
DE4115722A1
(de)
*
|
1991-05-14 |
1992-11-19 |
Boehringer Mannheim Gmbh |
Serumfreies medium zur kultivierung von saeugerzellen
|
US6270989B1
(en)
|
1991-11-05 |
2001-08-07 |
Transkaryotic Therapies, Inc. |
Protein production and delivery
|
US5968502A
(en)
|
1991-11-05 |
1999-10-19 |
Transkaryotic Therapies, Inc. |
Protein production and protein delivery
|
PT101031B
(pt)
|
1991-11-05 |
2002-07-31 |
Transkaryotic Therapies Inc |
Processo para o fornecimento de proteinas por terapia genetica
|
US5728536A
(en)
*
|
1993-07-29 |
1998-03-17 |
St. Jude Children's Research Hospital |
Jak kinases and regulation of Cytokine signal transduction
|
FR2686899B1
(fr)
*
|
1992-01-31 |
1995-09-01 |
Rhone Poulenc Rorer Sa |
Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
|
US6670178B1
(en)
|
1992-07-10 |
2003-12-30 |
Transkaryotic Therapies, Inc. |
In Vivo production and delivery of insulinotropin for gene therapy
|
US6531124B1
(en)
|
1992-07-10 |
2003-03-11 |
Transkaryotic Therapies, Inc. |
In vivo production and delivery of insulinotropin for gene therapy
|
CA2142453A1
(fr)
*
|
1992-09-09 |
1994-03-17 |
Tomio Morino |
Nk175203, nouvelle substance physiologiquement active; methode de preparation et utilisation en pharmacie
|
WO1994024160A2
(fr)
*
|
1993-04-21 |
1994-10-27 |
Brigham And Women's Hospital |
Erythropoïetines-muteines a activite renforcee
|
IL192290A0
(en)
*
|
1993-08-17 |
2008-12-29 |
Kirin Amgen Inc |
Erythropoietin analogs
|
US8192955B1
(en)
*
|
1994-01-03 |
2012-06-05 |
Genentech, Inc. |
Nucleic acids encoding MPL ligand (thrombopoietin), variants, and fragments thereof
|
US5888774A
(en)
*
|
1994-12-19 |
1999-03-30 |
Cangene Corporation |
Recombinant DNA molecules and expression vectors for erythropoietin
|
IL118201A
(en)
*
|
1995-05-11 |
2004-12-15 |
Roche Diagnostics Gmbh |
Preparation comprising a protein with human erythropoietin activity which is free of serum and non-recombinant mammalian protein and process for the preparation thereof
|
HUP9901069A2
(hu)
*
|
1995-06-07 |
1999-07-28 |
Affymax Technologies, N.V. |
Az eritropoietin receptorhoz kötődő vegyületek és peptidek
|
DK0833934T4
(da)
|
1995-06-15 |
2012-11-19 |
Crucell Holland Bv |
Pakningssystemer til human rekombinant adenovirus til anvendelse ved genterapi
|
EP0837942A1
(fr)
*
|
1995-07-07 |
1998-04-29 |
Boehringer Mannheim Gmbh |
Acide nucleique codant pour l'acide cmp-n-acetyle-neuraminique hydroxylase et son utilisation pour la production de glycoproteines modifiees
|
EP0752474A1
(fr)
*
|
1995-07-07 |
1997-01-08 |
Boehringer Mannheim Gmbh |
Acide nucléique codant pour une hydroxylase de l'acide CMP-N-acétyl-neuraminique et son utilisation pour la préparation de glycoprotéines modifiées
|
KR970010968A
(ko)
*
|
1995-08-24 |
1997-03-27 |
윤원영 |
오리 배 세포를 이용한 에리스로포이틴의 발현 시스템
|
ATE247667T1
(de)
|
1996-03-14 |
2003-09-15 |
Genentech Inc |
Gdnf-rezeptor und dessen verwendung
|
GB2318352A
(en)
*
|
1996-06-25 |
1998-04-22 |
Dejan Markovic |
Polypeptides mimicking the activity of human erythropoietin
|
US5952226A
(en)
*
|
1996-11-05 |
1999-09-14 |
Modex Therapeutiques |
Hypoxia responsive EPO producing cells
|
WO1998047922A2
(fr)
*
|
1997-04-21 |
1998-10-29 |
Glycozyme, Inc. |
Recherche des proteines et peptides glycosiles dans des fluides biologiques
|
US6475725B1
(en)
|
1997-06-20 |
2002-11-05 |
Baxter Aktiengesellschaft |
Recombinant cell clones having increased stability and methods of making and using the same
|
US6187564B1
(en)
*
|
1997-07-10 |
2001-02-13 |
Beth Israel Deaconess Medical Center |
DNA encoding erythropoietin multimers having modified 5′ and 3′ sequences and its use to prepare EPO therapeutics
|
DE19729769A1
(de)
|
1997-07-11 |
1999-01-14 |
Cardiogene Gentherapeutische S |
Transfektionssystem, seine Herstellung und Verwendung in der somatischen Gentherapie
|
US6017876A
(en)
*
|
1997-08-15 |
2000-01-25 |
Amgen Inc. |
Chemical modification of granulocyte-colony stimulating factor (G-CSF) bioactivity
|
US6897066B1
(en)
*
|
1997-09-26 |
2005-05-24 |
Athersys, Inc. |
Compositions and methods for non-targeted activation of endogenous genes
|
US7316923B1
(en)
|
1997-09-26 |
2008-01-08 |
Athersys, Inc. |
Compositions and methods for non-targeted activation of endogenous genes
|
AU752946B2
(en)
*
|
1997-10-16 |
2002-10-03 |
Avigenics, Inc. |
Vectors comprising a magnum-specific promoter for avian transgenesis
|
DE69824039T2
(de)
|
1997-12-08 |
2005-08-18 |
Lexigen Pharmaceuticals Corp., Lexington |
Heterodimäre fusionsproteine zur verwendung für gezielte immuntherapie und allgemeine immunerregung
|
EP1056858B1
(fr)
*
|
1998-02-19 |
2004-12-08 |
Eastern Virginia Medical School |
Proteine 3 (hzp3) humaine recombinee active de zona pellucida
|
US7037663B2
(en)
*
|
1998-02-19 |
2006-05-02 |
Eastern Virginia Medical School |
Human zona pellucida protein 3 and uses thereof
|
ATE271376T1
(de)
|
1998-02-23 |
2004-08-15 |
Cilag Ag Int |
Liposomale erythropoietin-dispersion
|
US20030105294A1
(en)
*
|
1998-02-25 |
2003-06-05 |
Stephen Gillies |
Enhancing the circulating half life of antibody-based fusion proteins
|
KR100434729B1
(ko)
*
|
1998-03-18 |
2004-11-03 |
주식회사 엘지생명과학 |
천연 추출물을 첨가하여 중국햄스터 난소 유래세포에서 에리스로포이에틴의 생산 증대방법
|
DE69927249T2
(de)
*
|
1998-03-27 |
2006-06-29 |
Cytos Biotechnology Ag |
Induzierendes alphavirengen- expressionssystem
|
AR019025A1
(es)
|
1998-04-09 |
2001-12-26 |
Roche Diagnostics Gmbh |
Uso de eritropoyetina en bajas dosis para producir un preparado farmaceutico para el tratamiento de hemocromatosis, preparado farmaceutico combinadoutilizado segun dicho uso y envase farmaceutico unitario que contiene al referido preparado farmaceutico combinado
|
WO1999052562A2
(fr)
*
|
1998-04-15 |
1999-10-21 |
Lexigen Pharmaceuticals Corp. |
Co-administration d'un inhibiteur de l'angiogenese pour renforcer la reponse immunitaire a mediation de proteine de fusion d'une cytokine d'anticorps
|
US6696411B1
(en)
*
|
1998-04-22 |
2004-02-24 |
Cornell Research Foundation, Inc. |
Canine erythropoietin gene and recombinant protein
|
JP2002512039A
(ja)
*
|
1998-04-22 |
2002-04-23 |
コーネル リサーチ ファンデーション インク. |
イヌエリスロポエチン遺伝子および組換えタンパク質
|
EP1088084B1
(fr)
*
|
1998-06-15 |
2006-09-13 |
GTC Biotherapeutics, Inc. |
Proteine de fusion de l'erythropoietine analogue-albumine serique humaine
|
US20050181482A1
(en)
*
|
2004-02-12 |
2005-08-18 |
Meade Harry M. |
Method for the production of an erythropoietin analog-human IgG fusion proteins in transgenic mammal milk
|
US6541033B1
(en)
|
1998-06-30 |
2003-04-01 |
Amgen Inc. |
Thermosensitive biodegradable hydrogels for sustained delivery of leptin
|
WO2000006205A1
(fr)
*
|
1998-07-29 |
2000-02-10 |
Invitrogen Corporation |
Expression regulee de proteines recombinantes au moyen de virus a arn
|
EP0984062A1
(fr)
*
|
1998-09-04 |
2000-03-08 |
Cytos Biotechnology AG |
Production d'érythropoeitine humaine
|
US6420339B1
(en)
|
1998-10-14 |
2002-07-16 |
Amgen Inc. |
Site-directed dual pegylation of proteins for improved bioactivity and biocompatibility
|
US6660843B1
(en)
|
1998-10-23 |
2003-12-09 |
Amgen Inc. |
Modified peptides as therapeutic agents
|
US7304150B1
(en)
|
1998-10-23 |
2007-12-04 |
Amgen Inc. |
Methods and compositions for the prevention and treatment of anemia
|
BR9917606A
(pt)
|
1998-11-06 |
2002-12-31 |
Bio Sidus S A |
Procedimento para a purificação de eritropoetina humana recombinante a partir de sobrenadantes de cultivo de células e eritropoetina humana recombinante obtida com tal procedimento
|
US6777205B1
(en)
|
1998-11-06 |
2004-08-17 |
Sterrenbeld Biotechnologie North America, Inc. |
Host cells expressing recombinant human erythropoietin
|
BR9905867A
(pt)
*
|
1998-11-06 |
2001-01-23 |
Bio Sidus S A |
Linhagem celular produtora de eritropoietina humana recombinante e a eritropoietina humana recombinante produzida por esta célula
|
BR9905868A
(pt)
|
1998-11-06 |
2001-01-23 |
Bio Sidus S A |
Procedimento de cultivo massivo de células de mamìfero para a obtenção de eritropoetina humana, recombinante e a eritropoetina humana recombinante obtida com tal procedimento
|
DE19857609A1
(de)
|
1998-12-14 |
2000-06-15 |
Hannelore Ehrenreich |
Verwendung von Erythropoietin zur Behandlung von cerebralen Ischämien des Menschen
|
US6451346B1
(en)
*
|
1998-12-23 |
2002-09-17 |
Amgen Inc |
Biodegradable pH/thermosensitive hydrogels for sustained delivery of biologically active agents
|
US6245740B1
(en)
|
1998-12-23 |
2001-06-12 |
Amgen Inc. |
Polyol:oil suspensions for the sustained release of proteins
|
DE19905501B4
(de)
|
1999-02-10 |
2005-05-19 |
MediGene AG, Gesellschaft für molekularbiologische Kardiologie und Onkologie |
Verfahren zur Herstellung eines rekombinanten Adeno-assoziierten Virus, geeignete Mittel hierzu sowie Verwendung zur Herstellung eines Arzneimittels
|
US7410941B1
(en)
|
1999-04-13 |
2008-08-12 |
The Kenneth S. Warren Institute, Inc. |
Methods for treatment of neurodegenerative conditions by peripherally administered erythropoietin
|
US7345019B1
(en)
*
|
1999-04-13 |
2008-03-18 |
The Kenneth S. Warren Institute, Inc. |
Modulation of excitable tissue function by peripherally administered erythropoietin
|
US7297680B2
(en)
*
|
1999-04-15 |
2007-11-20 |
Crucell Holland B.V. |
Compositions of erythropoietin isoforms comprising Lewis-X structures and high sialic acid content
|
US7504248B2
(en)
*
|
2001-12-07 |
2009-03-17 |
Crucell Holland B.V. |
Production of viruses viral isolates and vaccines
|
US20050170463A1
(en)
*
|
1999-04-15 |
2005-08-04 |
Abraham Bout |
Recombinant protein production in permanent amniocytic cells that comprise nucleic acid encoding adenovirus E1A and E1B proteins
|
US7604960B2
(en)
*
|
1999-04-15 |
2009-10-20 |
Crucell Holland B.V. |
Transient protein expression methods
|
US6855544B1
(en)
*
|
1999-04-15 |
2005-02-15 |
Crucell Holland B.V. |
Recombinant protein production in a human cell
|
US8236561B2
(en)
*
|
1999-04-15 |
2012-08-07 |
Crucell Holland B.V. |
Efficient production of IgA in recombinant mammalian cells
|
US20050164386A1
(en)
*
|
1999-04-15 |
2005-07-28 |
Uytdehaag Alphonsus G. |
Overexpression of enzymes involved in post-translational protein modifications in human cells
|
US6555343B1
(en)
|
1999-05-07 |
2003-04-29 |
Genentech Inc. |
Chimpanzee erythropoietin (CHEPO) polypeptides and nucleic acids encoding the same
|
IL145785A0
(en)
*
|
1999-05-07 |
2002-07-25 |
Genentech Inc |
Novel chimpanzee erythropoietin (chepo) polypeptides and nucleic acids encoding the same
|
US6831060B2
(en)
|
1999-05-07 |
2004-12-14 |
Genentech, Inc. |
Chimpanzee erythropoietin (CHEPO) polypeptides and nucleic acids encoding the same
|
AT409379B
(de)
|
1999-06-02 |
2002-07-25 |
Baxter Ag |
Medium zur protein- und serumfreien kultivierung von zellen
|
SK782002A3
(en)
|
1999-07-21 |
2003-08-05 |
Lexigen Pharm Corp |
FC fusion proteins for enhancing the immunogenicity of protein and peptide antigens
|
US7067110B1
(en)
|
1999-07-21 |
2006-06-27 |
Emd Lexigen Research Center Corp. |
Fc fusion proteins for enhancing the immunogenicity of protein and peptide antigens
|
US6737519B1
(en)
*
|
1999-07-30 |
2004-05-18 |
Genome Therapeutics Corporation |
Human genes relating to respiratory diseases and obesity
|
US6617135B1
(en)
*
|
1999-08-09 |
2003-09-09 |
Emd Lexigen Research Center Corp. |
Multiple cytokine protein complexes
|
US8106098B2
(en)
*
|
1999-08-09 |
2012-01-31 |
The General Hospital Corporation |
Protein conjugates with a water-soluble biocompatible, biodegradable polymer
|
AU2154401A
(en)
|
1999-11-12 |
2001-05-30 |
Merck Patent Gmbh |
Erythropoietin forms with improved properties
|
US20050202538A1
(en)
*
|
1999-11-12 |
2005-09-15 |
Merck Patent Gmbh |
Fc-erythropoietin fusion protein with improved pharmacokinetics
|
US6703480B1
(en)
|
1999-11-24 |
2004-03-09 |
Palani Balu |
Peptide dimers as agonists of the erythropoientin (EPO) receptor, and associated methods of synthesis and use
|
US7521220B2
(en)
*
|
1999-11-26 |
2009-04-21 |
Crucell Holland B.V. |
Production of vaccines
|
US7527961B2
(en)
*
|
1999-11-26 |
2009-05-05 |
Crucell Holland B.V. |
Production of vaccines
|
US7192759B1
(en)
*
|
1999-11-26 |
2007-03-20 |
Crucell Holland B.V. |
Production of vaccines
|
WO2001042442A2
(fr)
|
1999-12-10 |
2001-06-14 |
Cytos Biotechnology Ag |
Activation de genes endogenes basee sur un replicon
|
WO2001058957A2
(fr)
*
|
2000-02-11 |
2001-08-16 |
Lexigen Pharmaceuticals Corp. |
Amelioration de la demi-vie circulante de proteines de fusion a base d'anticorps
|
CA2405557C
(fr)
|
2000-04-12 |
2013-09-24 |
Human Genome Sciences, Inc. |
Proteines hybrides d'albumine
|
US20050100991A1
(en)
*
|
2001-04-12 |
2005-05-12 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
WO2001086498A2
(fr)
*
|
2000-05-12 |
2001-11-15 |
Cyril John Higgins |
Utilisation du web
|
MXPA02012734A
(es)
*
|
2000-06-29 |
2003-04-25 |
Merck Patent Gmbh |
Mejoramiento de las respuestas inmunes mediadas por la proteina de fusion anticuerpo-citocina, mediante tratamiento combinado con agentes mejoradores de la captacion de inmunocitocina.
|
US20020012982A1
(en)
*
|
2000-07-13 |
2002-01-31 |
Invitrogen Corporation |
Methods and compositions for rapid protein and peptide extraction and isolation using a lysis matrix
|
US7855229B2
(en)
*
|
2000-08-24 |
2010-12-21 |
University Of Tennessee Research Foundation |
Treating wasting disorders with selective androgen receptor modulators
|
US7919647B2
(en)
|
2000-08-24 |
2011-04-05 |
University Of Tennessee Research Foundation |
Selective androgen receptor modulators and methods of use thereof
|
US7645898B2
(en)
*
|
2000-08-24 |
2010-01-12 |
University Of Tennessee Research Foundation |
Selective androgen receptor modulators and method of use thereof
|
US7622503B2
(en)
|
2000-08-24 |
2009-11-24 |
University Of Tennessee Research Foundation |
Selective androgen receptor modulators and methods of use thereof
|
WO2002024899A2
(fr)
|
2000-09-25 |
2002-03-28 |
Valentis, Inc. |
Ameliorations apportees a un systeme de regulation d'une expression transgenique
|
US7087224B2
(en)
|
2000-10-31 |
2006-08-08 |
Amgen Inc. |
Method of treating anemia by administering IL-1ra
|
ES2361824T3
(es)
|
2000-12-20 |
2011-06-22 |
F. Hoffmann-La Roche Ag |
Conjugados de eritropoyetina (epo) con polietilenglicol (peg).
|
US20030072737A1
(en)
*
|
2000-12-29 |
2003-04-17 |
Michael Brines |
Tissue protective cytokines for the protection, restoration, and enhancement of responsive cells, tissues and organs
|
US7767643B2
(en)
*
|
2000-12-29 |
2010-08-03 |
The Kenneth S. Warren Institute, Inc. |
Protection, restoration, and enhancement of erythropoietin-responsive cells, tissues and organs
|
US6531121B2
(en)
*
|
2000-12-29 |
2003-03-11 |
The Kenneth S. Warren Institute, Inc. |
Protection and enhancement of erythropoietin-responsive cells, tissues and organs
|
KR100399337B1
(ko)
*
|
2001-02-07 |
2003-09-26 |
드림바이오젠 주식회사 |
단백질의 무세포 번역후수식법
|
MXPA03008031A
(es)
*
|
2001-03-07 |
2003-12-04 |
Merck Patent Gmbh |
Tecnologia de expresion para proteinas que contienen porcion de anticuerpo isotipo hibrida.
|
DE10112825A1
(de)
|
2001-03-16 |
2002-10-02 |
Fresenius Kabi De Gmbh |
HESylierung von Wirkstoffen in wässriger Lösung
|
US6992174B2
(en)
|
2001-03-30 |
2006-01-31 |
Emd Lexigen Research Center Corp. |
Reducing the immunogenicity of fusion proteins
|
CN100503639C
(zh)
|
2001-05-03 |
2009-06-24 |
默克专利有限公司 |
重组肿瘤特异性抗体及其应用
|
CA2446739A1
(fr)
*
|
2001-05-25 |
2002-12-05 |
Human Genome Sciences, Inc. |
Proteines hybrides beta-1 de chimiokine
|
EP1421104A4
(fr)
*
|
2001-08-02 |
2005-08-24 |
Trinity Biomedical Technology |
Proteines de zone pellucide humaine et methodes d'utilisation associees pour le diagnostic de la sterilite masculine
|
JP3993560B2
(ja)
*
|
2001-08-30 |
2007-10-17 |
ステム セル セラピューティクス インコーポレイテッド |
神経幹細胞の分化およびその治療用途
|
US20030104996A1
(en)
*
|
2001-08-30 |
2003-06-05 |
Tiansheng Li |
L-methionine as a stabilizer for NESP/EPO in HSA-free formulations
|
CA2460184A1
(fr)
*
|
2001-09-14 |
2003-03-27 |
Stem Cell Therapeutics Inc. |
Augmentation du nombre de cellules souche neuronales induites par la prolactine
|
US20030054551A1
(en)
*
|
2001-09-18 |
2003-03-20 |
Stem Cell Therapeutics Inc. |
Effect of growth hormone and IGF-1 on neural stem cells
|
WO2003045995A2
(fr)
*
|
2001-11-28 |
2003-06-05 |
Sandoz Gmbh |
Procede de culture de cellules
|
WO2003048334A2
(fr)
*
|
2001-12-04 |
2003-06-12 |
Merck Patent Gmbh |
Immunocytokines a selectivite modulee
|
US20070161608A1
(en)
*
|
2001-12-06 |
2007-07-12 |
Dalton James T |
Selective androgen receptor modulators for treating muscle wasting
|
US8853266B2
(en)
*
|
2001-12-06 |
2014-10-07 |
University Of Tennessee Research Foundation |
Selective androgen receptor modulators for treating diabetes
|
AU2002364587A1
(en)
*
|
2001-12-21 |
2003-07-30 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
EP2261250B1
(fr)
*
|
2001-12-21 |
2015-07-01 |
Human Genome Sciences, Inc. |
Protéines de fusion d'albumine et GCSF
|
EP1468099A2
(fr)
|
2002-01-17 |
2004-10-20 |
Lonza Biologics plc |
Cellules humaines auxotrophes pour la glutamine capables de produire des proteines et de se developper dans un milieu exempt de glutamine
|
DE10209821A1
(de)
|
2002-03-06 |
2003-09-25 |
Biotechnologie Ges Mittelhesse |
Kopplung von Proteinen an ein modifiziertes Polysaccharid
|
DE10209822A1
(de)
|
2002-03-06 |
2003-09-25 |
Biotechnologie Ges Mittelhesse |
Kopplung niedermolekularer Substanzen an ein modifiziertes Polysaccharid
|
US20030191056A1
(en)
|
2002-04-04 |
2003-10-09 |
Kenneth Walker |
Use of transthyretin peptide/protein fusions to increase the serum half-life of pharmacologically active peptides/proteins
|
US20040009902A1
(en)
*
|
2002-05-13 |
2004-01-15 |
Irving Boime |
CTP extended erythropoietin
|
PL374580A1
(en)
*
|
2002-07-01 |
2005-10-31 |
The Kenneth S.Warren Institute, Inc. |
Recombinant tissue protective cytokines and encoding nucleic acids thereof for protection, restoration, and enhancement of responsive cells, tissues, and organs
|
CN101058800B
(zh)
|
2002-07-09 |
2013-03-13 |
巴克斯特国际有限公司 |
用于细胞培养的无动物蛋白质培养基
|
DE10234192B4
(de)
|
2002-07-26 |
2009-11-26 |
Epoplus Gmbh Co.Kg |
Verwendung von Erythropoetin
|
CA2492442A1
(fr)
*
|
2002-07-31 |
2004-02-05 |
Stem Cell Therapeutics Inc. |
Procede d'amelioration de la proliferation, de la differentiation et de la survie de cellules souches neurales au moyen du polypeptide d'activation d'adenylate cyclase hypophysaire (pacap)
|
WO2004020576A2
(fr)
*
|
2002-08-31 |
2004-03-11 |
Cj Corp. |
Isoforme humaine glycosylee du facteur stimulant les colonies de granulocytes (g-csf)
|
CA2498319A1
(fr)
*
|
2002-09-09 |
2004-03-18 |
Nautilus Biotech |
Evolution rationnelle de cytokines pour une plus grande stabilite, les cytokines et molecules d'acide nucleique codant
|
DE20321793U1
(de)
|
2002-09-11 |
2010-06-02 |
Fresenius Kabi Deutschland Gmbh |
Hydroxyalkylstärke-Derivate
|
KR101174510B1
(ko)
|
2002-09-11 |
2012-08-16 |
프레제니우스 카비 도이치란트 게엠베하 |
하이드록시알킬전분화 폴리펩티드, 특히 하이드록시알킬전분화 에리트로포이에틴
|
EP1681303B1
(fr)
|
2002-09-11 |
2013-09-04 |
Fresenius Kabi Deutschland GmbH |
Polypeptides HASylés, en particulier érythropoiétine HASylée
|
DE60323756D1
(de)
|
2002-10-08 |
2008-11-06 |
Fresenius Kabi De Gmbh |
Pharmazeutisch aktive oligosaccharid-conjugate
|
ATE471946T1
(de)
*
|
2002-12-17 |
2010-07-15 |
Merck Patent Gmbh |
Humanisierter antikörper (h14.18) des maus antikörpers 14.18, der gd2 bindet und seine fusion mit il-2
|
EP1594530A4
(fr)
|
2003-01-22 |
2006-10-11 |
Human Genome Sciences Inc |
Proteines hybrides d'albumine
|
ZA200506196B
(en)
*
|
2003-02-03 |
2006-10-25 |
Japan Immuno Inc |
High-expression vector for animal cells
|
US8084424B2
(en)
*
|
2003-04-09 |
2011-12-27 |
University Of Utah Research Foundation |
Compositions and methods related to erythropoietin
|
US7459152B2
(en)
*
|
2003-04-23 |
2008-12-02 |
Rush University Medical Center |
Erythropoietin administration to improve graft survival
|
JP4865539B2
(ja)
*
|
2003-05-09 |
2012-02-01 |
クルセル ホランド ベー ヴェー |
E1不死化細胞の培養物及び該培養物を培養して該培養物から得られる産物の収量を増加させる方法
|
NZ543934A
(en)
*
|
2003-05-12 |
2008-06-30 |
Affymax Inc |
Novel spacer moiety for poly (ethylene glycol)-modified peptide-based compounds
|
KR101163683B1
(ko)
*
|
2003-05-12 |
2012-07-10 |
아피맥스, 인크. |
에리스로포이에틴 수용체에 결합하는 신규의 펩티드
|
KR101227666B1
(ko)
*
|
2003-05-12 |
2013-01-31 |
아피맥스, 인크. |
에리스로포이에틴 수용체에 결합하는 펩티드
|
CA2525464A1
(fr)
*
|
2003-05-12 |
2004-11-25 |
Qun Yin |
Nouveaux composes modifies par du poly(ethylene glycol) et leurs utilisations
|
DK1626992T3
(da)
*
|
2003-05-23 |
2010-09-20 |
Crucell Holland Bv |
Produktion af rekombinant IgM i PER.C6-celler
|
BRPI0411114B8
(pt)
|
2003-06-10 |
2021-05-25 |
Lg Chemical Ltd |
solução aquosa estável de eritropoetina humana, não contendo albumina de soro
|
EP2216415B2
(fr)
*
|
2003-08-01 |
2017-01-04 |
Life Technologies Corporation |
Compositions et procédés de préparation de courtes molécules d'ARN et d'autres acides nucléiques
|
WO2005014655A2
(fr)
|
2003-08-08 |
2005-02-17 |
Fresenius Kabi Deutschland Gmbh |
Conjugues d'amidon d'hydroxyalkyle et de proteine
|
US7645733B2
(en)
|
2003-09-29 |
2010-01-12 |
The Kenneth S. Warren Institute, Inc. |
Tissue protective cytokines for the treatment and prevention of sepsis and the formation of adhesions
|
RU2392314C2
(ru)
|
2003-12-30 |
2010-06-20 |
Аугустинус БАДЕР |
Способ регенерации ткани
|
JP2007517042A
(ja)
|
2003-12-30 |
2007-06-28 |
デュレクト コーポレーション |
活性物質、好ましくはgnrhの制御放出のための、好ましくはpegおよびplgの混合物を含有するポリマーインプラント
|
WO2005063808A1
(fr)
*
|
2003-12-31 |
2005-07-14 |
Merck Patent Gmbh |
Proteine hybride fc-erythropoietine a pharmacocinetique amelioree
|
DE102004004509B4
(de)
|
2004-01-23 |
2010-07-01 |
Epoplus Gmbh Co.Kg |
Einsatz von niedrig dosiertem Erythropoietin zur Stimulation endothelialer Vorläuferzellen sowie zur Organregeneration und Progressionsverlangsamung von Endorganschäden
|
US7846898B2
(en)
*
|
2004-02-13 |
2010-12-07 |
Stem Cell Therapeutics Corp. |
Pheromones and the luteinizing hormone for inducing proliferation of neural stem cells and neurogenesis
|
US7255288B2
(en)
*
|
2004-03-08 |
2007-08-14 |
Wan Shan Chan |
Aroma therapy for fountain
|
ES2390885T3
(es)
|
2004-03-11 |
2012-11-19 |
Fresenius Kabi Deutschland Gmbh |
Conjugados de hidroxialquilalmidón y una proteína
|
EP2336192A1
(fr)
|
2004-03-11 |
2011-06-22 |
Fresenius Kabi Deutschland GmbH |
Conjugues d'amidon hydroxyalkyle et d'une protein, preparer par amination réductive
|
US7588745B2
(en)
*
|
2004-04-13 |
2009-09-15 |
Si Options, Llc |
Silicon-containing products
|
US9889110B2
(en)
|
2004-06-07 |
2018-02-13 |
University Of Tennessee Research Foundation |
Selective androgen receptor modulator for treating hormone-related conditions
|
US20110237664A1
(en)
*
|
2004-06-07 |
2011-09-29 |
Dalton James T |
Selective androgen receptor modulators for treating diabetes
|
US9884038B2
(en)
|
2004-06-07 |
2018-02-06 |
University Of Tennessee Research Foundation |
Selective androgen receptor modulator and methods of use thereof
|
US20060094104A1
(en)
*
|
2004-10-29 |
2006-05-04 |
Leopold Grillberger |
Animal protein-free media for cultivation of cells
|
WO2006062685A2
(fr)
*
|
2004-11-11 |
2006-06-15 |
Affymax, Inc. |
Nouveaux peptides se liant au recepteur de l'erythropoietine
|
WO2006060148A2
(fr)
*
|
2004-11-11 |
2006-06-08 |
Affymax, Inc. |
Nouveaux peptides qui se lient au recepteur d'erythropoietine
|
WO2006061853A2
(fr)
*
|
2004-12-10 |
2006-06-15 |
Serum Institute Of India Limited |
Nouveaux composes erythropoietiques et leur procede de production
|
EP1848461A2
(fr)
*
|
2005-02-16 |
2007-10-31 |
Nektar Therapeutics Al, Corporation |
Conjugues d'une fraction d'epo et d'un polymere
|
US8324159B2
(en)
*
|
2005-06-03 |
2012-12-04 |
Affymax, Inc. |
Erythropoietin receptor peptide formulations and uses
|
US7919461B2
(en)
|
2005-06-03 |
2011-04-05 |
Affymax, Inc. |
Erythropoietin receptor peptide formulations and uses
|
US7550433B2
(en)
*
|
2005-06-03 |
2009-06-23 |
Affymax, Inc. |
Erythropoietin receptor peptide formulations and uses
|
AU2006285026B2
(en)
|
2005-08-31 |
2012-08-09 |
University Of Tennessee Research Foundation |
Treating renal disease, burns, wounds and spinal cord injury with selective androgen receptor modulators
|
EP1762250A1
(fr)
|
2005-09-12 |
2007-03-14 |
Fresenius Kabi Deutschland GmbH |
Conjugués d' amidon hydroxyalkyle et une substance active obtenue par ligation chimique via thiazolidine
|
WO2007036033A1
(fr)
|
2005-09-27 |
2007-04-05 |
Stem Cell Therapeutics Corp. |
Regulation par la prolactine de la proliferation des cellules precurseurs d'oligodendrocytes
|
US9388382B2
(en)
*
|
2005-10-05 |
2016-07-12 |
The Board Of Trustees Of The University Of Illinois |
Isolation of CD14 negative, CD45 positive and CD117 positive embryonic-like stem cells free of monocytes from human umbilical cord blood mononuclear cells
|
US20080260746A1
(en)
*
|
2005-11-24 |
2008-10-23 |
Laboratoires Serono Sa |
Erythropoietin Polypeptides and Uses Thereof
|
EP2495308A1
(fr)
|
2005-12-08 |
2012-09-05 |
Amgen Inc. |
Production améliorée de glycoprotéines au moyen de manganèse
|
KR101423344B1
(ko)
|
2006-01-04 |
2014-07-30 |
백스터 인터내셔널 인코포레이티드 |
올리고펩티드-무함유 세포 배양 배지를 이용하여 단백질을 발현시키는 방법
|
DE102006004008A1
(de)
|
2006-01-27 |
2007-08-02 |
Hannelore Prof. Dr. Dr. Ehrenreich |
Verfahren zur Behandlung und/oder Prophylaxe von Multipler Sklerose, sowie Verwendung von Erythropoietin zur Herstellung eines Arzneimittels zur intermittierenden Behandlung und/oder intermittierenden Prophylaxe von Multipler Sklerose
|
US7625564B2
(en)
|
2006-01-27 |
2009-12-01 |
Novagen Holding Corporation |
Recombinant human EPO-Fc fusion proteins with prolonged half-life and enhanced erythropoietic activity in vivo
|
JP2009530234A
(ja)
*
|
2006-03-17 |
2009-08-27 |
ステム セル セラピューティクス コーポレイション |
神経変性疾患の治療のためのlhまたはhcg、およびepoについての投与レジメン
|
WO2007108505A1
(fr)
|
2006-03-22 |
2007-09-27 |
Chugai Seiyaku Kabushiki Kaisha |
Préparation de solution d'érythropoïétine
|
CN101062407A
(zh)
|
2006-04-29 |
2007-10-31 |
中国科学院上海生命科学研究院 |
促红细胞生成素在预防或治疗视网膜损伤中的用途
|
PT2038252T
(pt)
|
2006-07-12 |
2016-12-16 |
Univ Tennessee Res Found |
Acilanilidos substituidos e métodos de utilização dos mesmos
|
EP2054074B8
(fr)
|
2006-08-04 |
2014-11-12 |
Prolong Pharmaceuticals, LLC |
Erythropoïétine modifiée
|
CA2661054A1
(fr)
|
2006-08-22 |
2008-02-28 |
Chugai Seiyaku Kabushiki Kaisha |
Agent preventif et/ou therapeutique pour une neuropathie peripherique
|
PL2054049T3
(pl)
|
2006-08-24 |
2016-11-30 |
|
Podstawione acyloanilidy i sposoby ich stosowania
|
CN102886052B
(zh)
|
2006-09-14 |
2014-07-30 |
迈德詹尼克斯医疗以色列有限公司 |
长效药物制剂
|
US8454948B2
(en)
|
2006-09-14 |
2013-06-04 |
Medgenics Medical Israel Ltd. |
Long lasting drug formulations
|
CA2666789C
(fr)
*
|
2006-10-18 |
2016-11-22 |
Yong Zhao |
Cellules souches de type embryonnaire derivees du sang peripherique d'un etre humain adulte et procedes d'utilisation associes
|
EP2120998B1
(fr)
|
2006-11-28 |
2013-08-07 |
HanAll Biopharma Co., Ltd. |
Polypeptides d'érythropoïétine modifiés et utilisation de ceux-ci dans des traitements
|
JP5065391B2
(ja)
*
|
2006-12-06 |
2012-10-31 |
日本ケミカルリサーチ株式会社 |
ヒトエリスロポエチンの製造方法
|
WO2008074851A2
(fr)
*
|
2006-12-19 |
2008-06-26 |
Nokad |
Procédé d'inhibition de l'expression d'érythropoïétine endogène (epo)
|
PE20130588A1
(es)
*
|
2007-02-02 |
2013-05-21 |
Amgen Inc |
Hepcidina, antagonistas de la hepcidina y metodos de uso
|
AR065613A1
(es)
|
2007-03-09 |
2009-06-17 |
Chugai Pharmaceutical Co Ltd |
Agentes de proteccion para organos transplantados
|
US20080260820A1
(en)
*
|
2007-04-19 |
2008-10-23 |
Gilles Borrelly |
Oral dosage formulations of protease-resistant polypeptides
|
US20100172919A1
(en)
|
2007-06-15 |
2010-07-08 |
Jan Grimm |
Noveltreatment for neurological disorders
|
WO2009010107A1
(fr)
|
2007-07-19 |
2009-01-22 |
Hannelore Ehrenreich |
Utilisation d'activation ou de stimulation du récepteur de l'epo pour l'amélioration du score edss dans des patients présentant une sclérose en plaques
|
BRPI0814465B1
(pt)
*
|
2007-07-26 |
2021-11-23 |
Novagen Holding Corporation |
Proteína de fusão, dímero, método para produzir uma proteína de fusão, linhagem de célula, usos de uma proteína de fusão e de uma composição farmacêutica e composição farmacêutica
|
US7968603B2
(en)
|
2007-09-11 |
2011-06-28 |
University Of Tennessee Research Foundation |
Solid forms of selective androgen receptor modulators
|
AU2008304111B2
(en)
|
2007-09-27 |
2014-04-24 |
Amgen Inc. |
Pharmaceutical formulations
|
EP3381445B1
(fr)
|
2007-11-15 |
2023-10-25 |
Amgen Inc. |
Formulation aqueuse d'anticorps stabilisée par des antioxydants pour administration parentérale
|
EP2070950A1
(fr)
|
2007-12-14 |
2009-06-17 |
Fresenius Kabi Deutschland GmbH |
Dérivés hydroxyalkylés de l'amidon et leur procédé de préparation
|
US9175078B2
(en)
|
2008-01-25 |
2015-11-03 |
Amgen Inc. |
Ferroportin antibodies and methods of use
|
CA2712606A1
(fr)
|
2008-02-08 |
2009-08-13 |
Ambrx, Inc. |
Polypeptides leptine modifies et leurs utilisations de marburg
|
EP2095829A1
(fr)
|
2008-02-27 |
2009-09-02 |
LEK Pharmaceuticals D.D. |
Sélénium contenant des agents à modifications et conjugués
|
US8653249B2
(en)
|
2008-02-27 |
2014-02-18 |
Fuso Pharmaceutical Industries, Ltd. |
Expression vector for mass production of foreign gene-derived protein using animal cell and use thereof
|
JP2011519279A
(ja)
|
2008-05-01 |
2011-07-07 |
アムジエン・インコーポレーテツド |
抗ヘプシジン抗体及び使用の方法
|
DE102008002210A1
(de)
|
2008-06-04 |
2009-12-10 |
Evonik Degussa Gmbh |
Verfahren zur fermentativen Herstellung von Erythropoietin
|
DE102008002209A1
(de)
|
2008-06-04 |
2009-12-10 |
Evonik Degussa Gmbh |
Verfahren zur Aufreinigung von Erythropoietin
|
WO2009155481A1
(fr)
*
|
2008-06-20 |
2009-12-23 |
Gtx, Inc. |
Métabolites de modulateurs de récepteur androgène sélectifs et procédés d'utilisation de ceux-ci
|
CA2736141C
(fr)
|
2008-09-23 |
2018-03-20 |
F. Hoffmann-La Roche Ag |
Purification de l'erythropoietine
|
CN102232085A
(zh)
|
2008-09-26 |
2011-11-02 |
Ambrx公司 |
修饰的动物促红细胞生成素多肽和其用途
|
EP2349332B1
(fr)
|
2008-11-13 |
2019-10-23 |
The General Hospital Corporation |
Procédés et compositions pour la régulation de l'homéostasie du fer par modulation de la protéine bmp-6
|
DE102008054716A1
(de)
|
2008-12-16 |
2010-06-17 |
Evonik Degussa Gmbh |
Inprozesskontrolle in einem Verfahren zur Herstellung von EPO
|
CN104342454A
(zh)
|
2008-12-22 |
2015-02-11 |
国立大学法人北海道大学 |
用于用动物细胞大量生产源自外源基因的蛋白质的表达载体及其应用
|
US20100272816A1
(en)
|
2009-04-27 |
2010-10-28 |
Wolfgang Rudinger |
Microcapsules comprising liver cells and erythropoietin, methods for preparing said microcapsules and methods for treating a patient comprising applying said microcapsules to the patient
|
CN107083400A
(zh)
|
2009-05-02 |
2017-08-22 |
建新公司 |
神经退行性疾病的基因治疗
|
KR20120117728A
(ko)
|
2009-09-23 |
2012-10-24 |
바이오제너릭스 에이지 |
재조합 인간 에리트로포이에틴(epo)의 정제 방법, 이렇게 정제된 epo 및 이를 포함하는 약학적 조성물
|
MX344382B
(es)
|
2009-10-23 |
2016-12-14 |
Amgen Inc * |
Adaptador de vial y sistema.
|
WO2011156373A1
(fr)
|
2010-06-07 |
2011-12-15 |
Amgen Inc. |
Dispositif d'administration de médicament
|
CA2802726A1
(fr)
|
2010-06-15 |
2011-12-22 |
Medgenics Medical Israel Ltd. |
Formulations pharmaceutiques a longue duree
|
EP2621519B1
(fr)
|
2010-09-28 |
2017-06-28 |
Aegerion Pharmaceuticals, Inc. |
Polypeptides de fusion de leptine-abd avec durée d'action prolonguée
|
US9480624B2
(en)
|
2011-03-31 |
2016-11-01 |
Amgen Inc. |
Vial adapter and system
|
EP2699293B8
(fr)
|
2011-04-20 |
2022-07-20 |
Amgen Inc. |
Appareil auto-injecteur
|
HUE043691T2
(hu)
|
2011-10-14 |
2019-09-30 |
Amgen Inc |
Befecskendezõ eszköz és összeszerelési eljárás
|
KR101443257B1
(ko)
|
2011-10-18 |
2014-09-19 |
주식회사 종근당 |
낮은 등전점을 갖는 에리스로포이에틴 유사체의 정제방법
|
US10350139B2
(en)
|
2011-10-25 |
2019-07-16 |
Corning Incorporated |
Pharmaceutical glass packaging assuring pharmaceutical sterility
|
US11707408B2
(en)
|
2011-10-25 |
2023-07-25 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
US9969683B2
(en)
|
2012-07-13 |
2018-05-15 |
Gtx, Inc. |
Method of treating estrogen receptor (ER)-positive breast cancers with selective androgen receptor modulator (SARMS)
|
MX2015000572A
(es)
|
2012-07-13 |
2015-09-23 |
Gtx Inc |
Metodo para tratar canceres de mama positivos a receptor de androgeno (ar) con modulador de receptor de androgeno selectivo (sarms).
|
US9622992B2
(en)
|
2012-07-13 |
2017-04-18 |
Gtx, Inc. |
Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs)
|
US9744149B2
(en)
|
2012-07-13 |
2017-08-29 |
Gtx, Inc. |
Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs)
|
US10314807B2
(en)
|
2012-07-13 |
2019-06-11 |
Gtx, Inc. |
Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS)
|
US10258596B2
(en)
|
2012-07-13 |
2019-04-16 |
Gtx, Inc. |
Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS)
|
US10987334B2
(en)
|
2012-07-13 |
2021-04-27 |
University Of Tennessee Research Foundation |
Method of treating ER mutant expressing breast cancers with selective androgen receptor modulators (SARMs)
|
US9650411B2
(en)
|
2012-08-07 |
2017-05-16 |
Kyowa Hakko Kirin Co., Ltd. |
Method of purifying protein
|
EP2906683B1
(fr)
|
2012-10-15 |
2017-05-31 |
Bristol-Myers Squibb Company |
Procédés de culture de cellules de mammifères en vue de la production de protéines
|
EP4234694A3
(fr)
|
2012-11-21 |
2023-09-06 |
Amgen Inc. |
Dispositif d'administration de médicaments
|
ES2797974T3
(es)
|
2013-03-14 |
2020-12-04 |
Translate Bio Inc |
Acidos ribonucleicos con nucleótidos modificados con 4-tio y procedimientos relacionados
|
TWI639453B
(zh)
|
2013-03-15 |
2018-11-01 |
美商安美基公司 |
用於注射器之匣盒
|
EP2970420A4
(fr)
|
2013-03-15 |
2016-08-17 |
Apotex Inc |
Stabilité de la formulation liquide améliorée d'érythropoïétine alpha par l'intermédiaire d'un traitement de purification
|
TWI592183B
(zh)
|
2013-03-15 |
2017-07-21 |
安美基公司 |
本體輪廓可調適之自動注射器裝置
|
EP2968503B1
(fr)
|
2013-03-15 |
2018-08-15 |
Intrinsic LifeSciences LLC |
Anticorps antihepcidine et leurs utilisations
|
JP6336564B2
(ja)
|
2013-03-15 |
2018-06-06 |
アムゲン・インコーポレーテッド |
薬物カセット、自動注入器、および自動注入器システム
|
EP2976117B1
(fr)
|
2013-03-22 |
2020-12-30 |
Amgen Inc. |
Injecteur et procédé d'assemblage
|
US9717649B2
(en)
|
2013-04-24 |
2017-08-01 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
US9707154B2
(en)
|
2013-04-24 |
2017-07-18 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
US9707155B2
(en)
|
2013-04-24 |
2017-07-18 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
US9849066B2
(en)
|
2013-04-24 |
2017-12-26 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
US9713572B2
(en)
|
2013-04-24 |
2017-07-25 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
US9603775B2
(en)
|
2013-04-24 |
2017-03-28 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
US9839579B2
(en)
|
2013-04-24 |
2017-12-12 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
US9707153B2
(en)
|
2013-04-24 |
2017-07-18 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
US9700486B2
(en)
|
2013-04-24 |
2017-07-11 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
US9717648B2
(en)
|
2013-04-24 |
2017-08-01 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
US9700485B2
(en)
|
2013-04-24 |
2017-07-11 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
US10196601B2
(en)
|
2013-08-20 |
2019-02-05 |
Lek Pharmaceuticals D.D. |
Cell culture medium and process for controlling α-amidation and/or C-terminal amino acid cleavage of polypeptides
|
AU2014340171B2
(en)
|
2013-10-24 |
2019-05-30 |
Amgen Inc. |
Injector and method of assembly
|
US20150118187A1
(en)
|
2013-10-24 |
2015-04-30 |
Medgenics Medical Israel Ltd. |
Micro-organs providing sustained delivery of a therapeutic polypeptide and methods of use thereof
|
EP3501575B1
(fr)
|
2013-10-24 |
2021-12-01 |
Amgen Inc. |
Système de distribution de médicaments équipé d'un dispositif de commande sensible à la température
|
US10994112B2
(en)
|
2014-02-05 |
2021-05-04 |
Amgen Inc. |
Drug delivery system with electromagnetic field generator
|
MX2016014561A
(es)
|
2014-05-07 |
2017-06-21 |
Amgen Inc |
Autoinyetor con elementos reductores del shock.
|
US10328082B2
(en)
|
2014-05-30 |
2019-06-25 |
Pfizer Inc. |
Methods of use and combinations
|
MX2016015854A
(es)
|
2014-06-03 |
2017-07-19 |
Amgen Inc |
Sistema de suministro de farmacos controlable y metodo de uso.
|
CA2961917A1
(fr)
|
2014-09-22 |
2016-03-31 |
Intrinsic Lifesciences Llc |
Anticorps anti-hepcidine humanises et utilisations de ceux-ci
|
EP3943135A3
(fr)
|
2014-10-14 |
2022-06-29 |
Amgen Inc. |
Dispositif d'injection de médicament avec indicateurs visuels et audibles
|
ES2785311T3
(es)
|
2014-12-19 |
2020-10-06 |
Amgen Inc |
Dispositivo de administración de fármacos con botón móvil o campo de interfaz de usuario
|
EP3233163B1
(fr)
|
2014-12-19 |
2021-10-13 |
Amgen Inc. |
Dispositif d'administration de médicament avec détecteur de proximité
|
WO2016133947A1
(fr)
|
2015-02-17 |
2016-08-25 |
Amgen Inc. |
Dispositif d'administration de médicament à sécurisation assistée par dépression et/ou retour d'informations
|
JP2018512184A
(ja)
|
2015-02-27 |
2018-05-17 |
アムジエン・インコーポレーテツド |
針ガードの移動に対する抵抗力の閾値が調整可能な針ガード機構を備えた薬物送達装置
|
WO2017039786A1
(fr)
|
2015-09-02 |
2017-03-09 |
Amgen Inc. |
Adaptateur d'ensemble de seringue pour une seringue
|
WO2017068051A1
(fr)
|
2015-10-21 |
2017-04-27 |
Lek Pharmaceuticals D.D. |
Dendron à base de peg et son procédé de production
|
EP3386573B1
(fr)
|
2015-12-09 |
2019-10-02 |
Amgen Inc. |
Auto-injecteur avec capuchon de signalisation
|
US11154661B2
(en)
|
2016-01-06 |
2021-10-26 |
Amgen Inc. |
Auto-injector with signaling electronics
|
WO2017160799A1
(fr)
|
2016-03-15 |
2017-09-21 |
Amgen Inc. |
Réduction de la probabilité de casse du verre dans des dispositifs d'administration de médicament
|
WO2017189089A1
(fr)
|
2016-04-29 |
2017-11-02 |
Amgen Inc. |
Dispositif d'administration de médicament avec étiquette de messagerie
|
WO2017192287A1
(fr)
|
2016-05-02 |
2017-11-09 |
Amgen Inc. |
Adaptateur de seringue et guide pour remplir un injecteur sur le corps
|
MX2018013616A
(es)
|
2016-05-13 |
2019-02-21 |
Amgen Inc |
Montaje de cubierta protectora de vial.
|
EP3458988B1
(fr)
|
2016-05-16 |
2023-10-18 |
Amgen Inc. |
Chiffrement de données dans des dispositifs médicaux à capacité de calcul limitée
|
EP3465124A1
(fr)
|
2016-06-03 |
2019-04-10 |
Amgen Inc. |
Appareils et procédés d'essai au choc destinés aux dispositifs d'administration de médicaments
|
WO2018004842A1
(fr)
|
2016-07-01 |
2018-01-04 |
Amgen Inc. |
Dispositif d'administration de médicament présentant un risque réduit au minimum de fracture de composant lors d'événements d'impact
|
US20190328965A1
(en)
|
2016-08-17 |
2019-10-31 |
Amgen Inc. |
Drug delivery device with placement detection
|
US20200261643A1
(en)
|
2016-10-25 |
2020-08-20 |
Amgen Inc. |
On-body injector
|
JP2020503976A
(ja)
|
2017-01-17 |
2020-02-06 |
アムジエン・インコーポレーテツド |
注入デバイスならびに関連する使用および組立方法
|
AU2018221351B2
(en)
|
2017-02-17 |
2023-02-23 |
Amgen Inc. |
Insertion mechanism for drug delivery device
|
EP3582825A1
(fr)
|
2017-02-17 |
2019-12-25 |
Amgen Inc. |
Dispositif d'administration de médicament à trajet d'écoulement de fluide stérile et procédé d'assemblage associé
|
JP2020508803A
(ja)
|
2017-03-06 |
2020-03-26 |
アムジエン・インコーポレーテツド |
作動防止特徴部を備える薬物送達デバイス
|
AU2018230546B2
(en)
|
2017-03-07 |
2024-03-21 |
Amgen Inc. |
Needle insertion by overpressure
|
US11986624B2
(en)
|
2017-03-09 |
2024-05-21 |
Amgen Inc. |
Insertion mechanism for drug delivery device
|
WO2018172219A1
(fr)
|
2017-03-20 |
2018-09-27 |
F. Hoffmann-La Roche Ag |
Procédé de glyco-ingénierie in vitro d'une protéine stimulant l'érythropoïèse
|
DK3600491T3
(da)
|
2017-03-28 |
2023-10-23 |
Amgen Inc |
Stempelstang og sprøjtekonstruktionssystem samt fremgangsmåde
|
EP3634539A1
(fr)
|
2017-06-08 |
2020-04-15 |
Amgen Inc. |
Ensemble de seringue d'un appareil d'administration de médicament et procédé d'assemblage
|
MX2019014615A
(es)
|
2017-06-08 |
2020-02-07 |
Amgen Inc |
Dispositivo de administracion de farmacos accionado por par de torsion.
|
KR102268647B1
(ko)
|
2017-06-12 |
2021-06-23 |
한국코러스 주식회사 |
안정성이 향상된 에리스로포이에틴 조성물 및 이의 제조방법
|
WO2018236619A1
(fr)
|
2017-06-22 |
2018-12-27 |
Amgen Inc. |
Réduction des impacts/chocs d'activation d'un dispositif
|
US11395880B2
(en)
|
2017-06-23 |
2022-07-26 |
Amgen Inc. |
Electronic drug delivery device
|
EP3651832B1
(fr)
|
2017-07-14 |
2023-12-13 |
Amgen Inc. |
Système d'insertion-rétractation d'aiguille présentant un système à ressort en double torsion
|
US11672733B2
(en)
|
2017-07-21 |
2023-06-13 |
Amgen Inc. |
Gas permeable sealing member for drug container and methods of assembly
|
EP3658206A1
(fr)
|
2017-07-25 |
2020-06-03 |
Amgen Inc. |
Dispositif d'administration de médicament doté d'un système d'accès à un récipient et procédé d'assemblage associé
|
EP4085942A1
(fr)
|
2017-07-25 |
2022-11-09 |
Amgen Inc. |
Dispositif d'administration de médicament avec module d'engrenage et procédé d'assemblage associé
|
WO2019032482A2
(fr)
|
2017-08-09 |
2019-02-14 |
Amgen Inc. |
Système d'administration de médicament à chambre sous pression hydraulique-pneumatique
|
EP3668567A1
(fr)
|
2017-08-18 |
2020-06-24 |
Amgen Inc. |
Injecteur sur-corps avec patch adhésif stérile
|
US11103636B2
(en)
|
2017-08-22 |
2021-08-31 |
Amgen Inc. |
Needle insertion mechanism for drug delivery device
|
EP3691717B1
(fr)
|
2017-10-04 |
2023-02-08 |
Amgen Inc. |
Adaptateur d'écoulement destiné à un dispositif d'administration de médicament
|
ES2971450T3
(es)
|
2017-10-06 |
2024-06-05 |
Amgen Inc |
Dispositivo de administración de fármacos con conjunto de enclavamiento y procedimiento de montaje correspondiente
|
MA50348A
(fr)
|
2017-10-09 |
2020-08-19 |
Amgen Inc |
Dispositif d'administration de médicament comprenant un ensemble d'entraînement et procédé d'assemblage associé
|
US11305026B2
(en)
|
2017-11-03 |
2022-04-19 |
Amgen Inc. |
Systems and approaches for sterilizing a drug delivery device
|
WO2019090303A1
(fr)
|
2017-11-06 |
2019-05-09 |
Amgen Inc. |
Ensembles de remplissage-finition et procédés associés
|
EP3706830B1
(fr)
|
2017-11-06 |
2024-08-07 |
Amgen Inc. |
Dispositif d'administration de médicament avec détection de positionnement et de débit
|
CA3079665A1
(fr)
|
2017-11-10 |
2019-05-16 |
Amgen Inc. |
Pistons pour dispositifs d'administration de medicament
|
JP7370969B2
(ja)
|
2017-11-16 |
2023-10-30 |
アムジエン・インコーポレーテツド |
薬物送達デバイスの扉ラッチ機構
|
MA50903A
(fr)
|
2017-11-16 |
2021-05-12 |
Amgen Inc |
Auto-injecteur avec détection de décrochage et de point d'extrémité
|
EP3805396B1
(fr)
|
2018-05-24 |
2024-09-11 |
National University Corporation Hokkaido University |
Nouveau vecteur et utilisation associée
|
US10835685B2
(en)
|
2018-05-30 |
2020-11-17 |
Amgen Inc. |
Thermal spring release mechanism for a drug delivery device
|
US11083840B2
(en)
|
2018-06-01 |
2021-08-10 |
Amgen Inc. |
Modular fluid path assemblies for drug delivery devices
|
US20210260279A1
(en)
|
2018-07-24 |
2021-08-26 |
Amgen Inc. |
Hybrid drug delivery devices with optional grip portion and related method of preparation
|
US12115360B2
(en)
|
2018-07-24 |
2024-10-15 |
Amgen Inc. |
Hybrid drug delivery devices with grip portion
|
MA53375A
(fr)
|
2018-07-24 |
2021-06-02 |
Amgen Inc |
Dispositifs d'administration pour l'administration de médicaments
|
US12042645B2
(en)
|
2018-07-24 |
2024-07-23 |
Amgen Inc. |
Delivery devices for administering drugs
|
CA3103105A1
(fr)
|
2018-07-31 |
2020-02-06 |
Amgen Inc. |
Ensemble de trajet de fluide pour dispositif d'administration de medicament
|
JP2022500095A
(ja)
|
2018-09-24 |
2022-01-04 |
アムジエン・インコーポレーテツド |
インターベンション投薬システム及び方法
|
IL281469B2
(en)
|
2018-09-28 |
2024-08-01 |
Amgen Inc |
Assembling a memory alloy ejector activation assembly for a drug delivery device
|
WO2020072577A1
(fr)
|
2018-10-02 |
2020-04-09 |
Amgen Inc. |
Systèmes d'injection pour administration de médicament avec transmission de force interne
|
MA53818A
(fr)
|
2018-10-05 |
2022-01-12 |
Amgen Inc |
Dispositif d'administration de médicament ayant un indicateur de dose
|
EA202191038A1
(ru)
|
2018-10-15 |
2021-07-06 |
Эмджен Инк. |
Способ платформенной сборки для устройства доставки лекарственного средства
|
AR116704A1
(es)
|
2018-10-15 |
2021-06-02 |
Amgen Inc |
Dispositivo de administración de fármacos con mecanismo de amortiguación
|
TWI831847B
(zh)
|
2018-11-01 |
2024-02-11 |
美商安進公司 |
部分針頭縮回之藥物遞送裝置及其操作方法
|
AU2019370159A1
(en)
|
2018-11-01 |
2021-04-22 |
Amgen Inc. |
Drug delivery devices with partial drug delivery member retraction
|
US11213620B2
(en)
|
2018-11-01 |
2022-01-04 |
Amgen Inc. |
Drug delivery devices with partial drug delivery member retraction
|
MX2021012557A
(es)
|
2019-04-24 |
2021-11-12 |
Amgen Inc |
Conjuntos y metodos de verificacion de esterilizacion de jeringuillas.
|
WO2021041067A2
(fr)
|
2019-08-23 |
2021-03-04 |
Amgen Inc. |
Dispositif d'administration de médicament doté de composants configurables de mise en prise de protection d'aiguille et méthodes associées
|
WO2022159414A1
(fr)
|
2021-01-22 |
2022-07-28 |
University Of Rochester |
Érythropoïétine pour un dysfonctionnement gastrointestinal
|
US20240208680A1
(en)
|
2021-05-21 |
2024-06-27 |
Amgen Inc. |
Method of optimizing a filling recipe for a drug container
|
WO2023275715A1
(fr)
|
2021-06-30 |
2023-01-05 |
Pfizer Inc. |
Métabolites de modulateurs sélectifs du récepteur des androgènes
|
WO2023209074A1
(fr)
|
2022-04-28 |
2023-11-02 |
Institut National de la Santé et de la Recherche Médicale |
Procédés de restauration de l'érythropoïèse chez des patients souffrant d'un syndrome myélodysplasique mutant sf3b1, par la correction du mauvais épissage de la coasy
|
WO2024094457A1
(fr)
|
2022-11-02 |
2024-05-10 |
F. Hoffmann-La Roche Ag |
Procédé de production de compositions de glycoprotéines
|