MX2016014561A - Autoinyetor con elementos reductores del shock. - Google Patents
Autoinyetor con elementos reductores del shock.Info
- Publication number
- MX2016014561A MX2016014561A MX2016014561A MX2016014561A MX2016014561A MX 2016014561 A MX2016014561 A MX 2016014561A MX 2016014561 A MX2016014561 A MX 2016014561A MX 2016014561 A MX2016014561 A MX 2016014561A MX 2016014561 A MX2016014561 A MX 2016014561A
- Authority
- MX
- Mexico
- Prior art keywords
- plunger
- stopper
- drug
- acting
- container
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3129—Syringe barrels
- A61M5/3134—Syringe barrels characterised by constructional features of the distal end, i.e. end closest to the tip of the needle cannula
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16F—SPRINGS; SHOCK-ABSORBERS; MEANS FOR DAMPING VIBRATION
- F16F9/00—Springs, vibration-dampers, shock-absorbers, or similarly-constructed movement-dampers using a fluid or the equivalent as damping medium
- F16F9/06—Springs, vibration-dampers, shock-absorbers, or similarly-constructed movement-dampers using a fluid or the equivalent as damping medium using both gas and liquid
- F16F9/08—Springs, vibration-dampers, shock-absorbers, or similarly-constructed movement-dampers using a fluid or the equivalent as damping medium using both gas and liquid where gas is in a chamber with a flexible wall
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16F—SPRINGS; SHOCK-ABSORBERS; MEANS FOR DAMPING VIBRATION
- F16F9/00—Springs, vibration-dampers, shock-absorbers, or similarly-constructed movement-dampers using a fluid or the equivalent as damping medium
- F16F9/10—Springs, vibration-dampers, shock-absorbers, or similarly-constructed movement-dampers using a fluid or the equivalent as damping medium using liquid only; using a fluid of which the nature is immaterial
- F16F9/103—Devices with one or more members moving linearly to and fro in chambers, any throttling effect being immaterial, i.e. damping by viscous shear effect only
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16F—SPRINGS; SHOCK-ABSORBERS; MEANS FOR DAMPING VIBRATION
- F16F9/00—Springs, vibration-dampers, shock-absorbers, or similarly-constructed movement-dampers using a fluid or the equivalent as damping medium
- F16F9/10—Springs, vibration-dampers, shock-absorbers, or similarly-constructed movement-dampers using a fluid or the equivalent as damping medium using liquid only; using a fluid of which the nature is immaterial
- F16F9/14—Devices with one or more members, e.g. pistons, vanes, moving to and fro in chambers and using throttling effect
- F16F9/16—Devices with one or more members, e.g. pistons, vanes, moving to and fro in chambers and using throttling effect involving only straight-line movement of the effective parts
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16F—SPRINGS; SHOCK-ABSORBERS; MEANS FOR DAMPING VIBRATION
- F16F9/00—Springs, vibration-dampers, shock-absorbers, or similarly-constructed movement-dampers using a fluid or the equivalent as damping medium
- F16F9/10—Springs, vibration-dampers, shock-absorbers, or similarly-constructed movement-dampers using a fluid or the equivalent as damping medium using liquid only; using a fluid of which the nature is immaterial
- F16F9/14—Devices with one or more members, e.g. pistons, vanes, moving to and fro in chambers and using throttling effect
- F16F9/16—Devices with one or more members, e.g. pistons, vanes, moving to and fro in chambers and using throttling effect involving only straight-line movement of the effective parts
- F16F9/18—Devices with one or more members, e.g. pistons, vanes, moving to and fro in chambers and using throttling effect involving only straight-line movement of the effective parts with a closed cylinder and a piston separating two or more working spaces therein
- F16F9/20—Devices with one or more members, e.g. pistons, vanes, moving to and fro in chambers and using throttling effect involving only straight-line movement of the effective parts with a closed cylinder and a piston separating two or more working spaces therein with the piston-rod extending through both ends of the cylinder, e.g. constant-volume dampers
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16F—SPRINGS; SHOCK-ABSORBERS; MEANS FOR DAMPING VIBRATION
- F16F9/00—Springs, vibration-dampers, shock-absorbers, or similarly-constructed movement-dampers using a fluid or the equivalent as damping medium
- F16F9/32—Details
- F16F9/3207—Constructional features
- F16F9/3228—Constructional features of connections between pistons and piston rods
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16F—SPRINGS; SHOCK-ABSORBERS; MEANS FOR DAMPING VIBRATION
- F16F9/00—Springs, vibration-dampers, shock-absorbers, or similarly-constructed movement-dampers using a fluid or the equivalent as damping medium
- F16F9/32—Details
- F16F9/34—Special valve constructions; Shape or construction of throttling passages
- F16F9/348—Throttling passages in the form of annular discs or other plate-like elements which may or may not have a spring action, operating in opposite directions or singly, e.g. annular discs positioned on top of the valve or piston body
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16F—SPRINGS; SHOCK-ABSORBERS; MEANS FOR DAMPING VIBRATION
- F16F9/00—Springs, vibration-dampers, shock-absorbers, or similarly-constructed movement-dampers using a fluid or the equivalent as damping medium
- F16F9/32—Details
- F16F9/34—Special valve constructions; Shape or construction of throttling passages
- F16F9/348—Throttling passages in the form of annular discs or other plate-like elements which may or may not have a spring action, operating in opposite directions or singly, e.g. annular discs positioned on top of the valve or piston body
- F16F9/3481—Throttling passages in the form of annular discs or other plate-like elements which may or may not have a spring action, operating in opposite directions or singly, e.g. annular discs positioned on top of the valve or piston body characterised by shape or construction of throttling passages in piston
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16F—SPRINGS; SHOCK-ABSORBERS; MEANS FOR DAMPING VIBRATION
- F16F9/00—Springs, vibration-dampers, shock-absorbers, or similarly-constructed movement-dampers using a fluid or the equivalent as damping medium
- F16F9/32—Details
- F16F9/36—Special sealings, including sealings or guides for piston-rods
- F16F9/361—Sealings of the bellows-type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M2005/2086—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically having piston damping means, e.g. axially or rotationally acting retarders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3143—Damping means for syringe components executing relative movements, e.g. retarders or attenuators slowing down or timing syringe mechanisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
- A61M5/321—Means for protection against accidental injuries by used needles
- A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
Landscapes
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Vascular Medicine (AREA)
- Environmental & Geological Engineering (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Abstract
Un dispositivo, método y sistema de inyección para la administración de fármacos incluye un contenedor primario para almacenar un fármaco, donde el contenedor tiene un tapón móvil dispuesto en el contenedor para expulsar el fármaco, un mecanismo de inyección que comprende un émbolo para actuar sobre el tapón y una fuente de energía para ejercer una fuerza sobre el émbolo a efectos de hacer que el émbolo actúe sobre el tapón para expulsar el fármaco, dicha fuerza genera que el émbolo se acelere hasta una velocidad antes de actuar sobre el tapón, y un mecanismo de amortiguamiento para reducir la velocidad del émbolo antes de que éste actúe sobre el tapón. El mecanismo de amortiguación puede incluir un amortiguador o un material que absorbe energía asociado con el émbolo. Como alternativa o adicionalmente, los mecanismos de amortiguación pueden incluir un material de absorción dispuesto entre elementos de soporte de un estuche exterior del dispositivo de inyección y el contenedor primario.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461990063P | 2014-05-07 | 2014-05-07 | |
PCT/US2015/029485 WO2015171777A1 (en) | 2014-05-07 | 2015-05-06 | Autoinjector with shock reducing elements |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2016014561A true MX2016014561A (es) | 2017-06-21 |
Family
ID=53200314
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2016014561A MX2016014561A (es) | 2014-05-07 | 2015-05-06 | Autoinyetor con elementos reductores del shock. |
Country Status (12)
Country | Link |
---|---|
US (2) | US10722655B2 (es) |
EP (2) | EP3785749A1 (es) |
JP (3) | JP6640113B2 (es) |
KR (1) | KR102496507B1 (es) |
CN (1) | CN106413779B (es) |
AU (1) | AU2015256082C1 (es) |
BR (1) | BR112016025852B1 (es) |
CA (2) | CA2945026C (es) |
IL (1) | IL247935B (es) |
MX (1) | MX2016014561A (es) |
SG (2) | SG10201811702TA (es) |
WO (1) | WO2015171777A1 (es) |
Families Citing this family (39)
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JP2016163642A (ja) * | 2015-03-06 | 2016-09-08 | 大成化工株式会社 | 針付きバレル及びこれを備えたシリンジ |
FR3036966B1 (fr) * | 2015-06-05 | 2021-10-01 | Aptar France Sas | Autoinjecteur |
TW201731539A (zh) * | 2015-11-27 | 2017-09-16 | 賽諾菲阿凡提斯德意志有限公司 | 自動注射器(一) |
JOP20170042B1 (ar) | 2016-02-12 | 2022-09-15 | Amgen Inc | وسيلة توصيل عقار، طريقة تصنيعه وطريقة استخدامه |
EP4035711A1 (en) * | 2016-03-15 | 2022-08-03 | Amgen Inc. | Reducing probability of glass breakage in drug delivery devices |
JP7074684B2 (ja) | 2016-04-08 | 2022-05-24 | アムジエン・インコーポレーテツド | 薬物送達デバイス、製造方法、及び使用方法 |
US10549044B2 (en) * | 2016-06-09 | 2020-02-04 | Becton, Dickinson And Company | Spacer assembly for drug delivery system |
US20180015224A1 (en) * | 2016-07-13 | 2018-01-18 | California Institute Of Technology | Dampers and Methods for Performing Measurements in an Autoinjector |
GB2553770A (en) * | 2016-09-09 | 2018-03-21 | Owen Mumford Ltd | Injection device |
EP3534989A1 (en) | 2016-11-01 | 2019-09-11 | Sanofi-Aventis Deutschland GmbH | Feedback mechanism for an injection device |
EP3348294A1 (en) * | 2017-01-13 | 2018-07-18 | Carebay Europe Ltd. | Medicament delivery device |
AU2018210301A1 (en) * | 2017-01-17 | 2019-08-01 | Amgen Inc. | Injection devices and related methods of use and assembly |
CA3063920A1 (en) * | 2017-06-22 | 2018-12-27 | Amgen Inc. | Device activation impact/shock reduction |
CN112292167B (zh) * | 2018-04-19 | 2023-01-20 | 赛诺菲 | 注射装置中的力减小 |
CN112312948B (zh) * | 2018-04-19 | 2022-12-02 | 赛诺菲 | 用于注射装置的缓冲器 |
MA53815A (fr) * | 2018-10-02 | 2022-01-05 | Amgen Inc | Systèmes d'injection pour administration de médicament avec transmission de force interne |
TWI831847B (zh) * | 2018-11-01 | 2024-02-11 | 美商安進公司 | 部分針頭縮回之藥物遞送裝置及其操作方法 |
WO2020091956A1 (en) | 2018-11-01 | 2020-05-07 | Amgen Inc. | Drug delivery devices with partial drug delivery member retraction |
CN114450050A (zh) * | 2019-09-30 | 2022-05-06 | 美国安进公司 | 药物递送装置 |
JP7075977B2 (ja) | 2020-10-09 | 2022-05-26 | 成田空港給油施設株式会社 | シリンジ |
US11311666B1 (en) | 2021-02-18 | 2022-04-26 | Fresenius Kabi Deutschland Gmbh | Modular wearable medicament delivery device and method of use thereof |
US11464902B1 (en) | 2021-02-18 | 2022-10-11 | Fresenius Kabi Deutschland Gmbh | Wearable medicament delivery device with compressible reservoir and method of use thereof |
US11872369B1 (en) | 2021-02-18 | 2024-01-16 | Fresenius Kabi Deutschland Gmbh | Wearable medicament delivery device with leakage and skin contact sensing and method of use thereof |
US11607505B1 (en) | 2021-02-19 | 2023-03-21 | Fresenius Kabi Deutschland Gmbh | Wearable injector with sterility sensors |
US11406755B1 (en) | 2021-02-19 | 2022-08-09 | Fresenius Kabi Deutschland Gmbh | Sensing fluid flow irregularities in an on-body injector |
US11426523B1 (en) | 2021-02-19 | 2022-08-30 | Fresenius Kabi Deutschland Gmbh | Drug delivery assembly including a removable cartridge |
US11413394B1 (en) | 2021-02-19 | 2022-08-16 | Fresenius Kabi Deutschland Gmbh | Display for wearable drug delivery device |
US11344682B1 (en) | 2021-02-19 | 2022-05-31 | Fresenius Kabi Deutschland Gmbh | Drug supply cartridge with visual use indicator and delivery devices that use the same |
US11633537B1 (en) | 2021-02-19 | 2023-04-25 | Fresenius Kabi Deutschland Gmbh | Drug delivery assembly including a pre-filled cartridge |
US11497847B1 (en) | 2021-02-19 | 2022-11-15 | Fresenius Kabi Deutschland Gmbh | Wearable injector with adhesive substrate |
JPWO2022191136A1 (es) * | 2021-03-12 | 2022-09-15 | ||
WO2022203830A1 (en) * | 2021-03-25 | 2022-09-29 | Amgen Inc. | Drug delivery device |
US11419976B1 (en) | 2021-04-30 | 2022-08-23 | Fresenius Kabi Deutschland Gmbh | Wearable drug delivery device with pressurized fluid dispensing |
US11529459B1 (en) | 2021-04-30 | 2022-12-20 | Fresenius Kabi Deutschland Gmbh | Wearable injector with adhesive module |
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-
2015
- 2015-05-06 US US15/302,116 patent/US10722655B2/en active Active
- 2015-05-06 AU AU2015256082A patent/AU2015256082C1/en active Active
- 2015-05-06 WO PCT/US2015/029485 patent/WO2015171777A1/en active Application Filing
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- 2015-05-06 KR KR1020167029388A patent/KR102496507B1/ko active IP Right Grant
- 2015-05-06 MX MX2016014561A patent/MX2016014561A/es unknown
- 2015-05-06 CN CN201580022028.8A patent/CN106413779B/zh active Active
- 2015-05-06 CA CA2945026A patent/CA2945026C/en active Active
- 2015-05-06 EP EP20200261.4A patent/EP3785749A1/en active Pending
- 2015-05-06 JP JP2016566215A patent/JP6640113B2/ja active Active
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WO2015171777A1 (en) | 2015-11-12 |
SG10201811702TA (en) | 2019-01-30 |
KR20160149198A (ko) | 2016-12-27 |
US20200316303A1 (en) | 2020-10-08 |
CA3193070A1 (en) | 2015-11-12 |
JP6640113B2 (ja) | 2020-02-05 |
EP3139977B1 (en) | 2021-02-17 |
CA2945026C (en) | 2023-10-10 |
EP3139977A1 (en) | 2017-03-15 |
JP7487257B2 (ja) | 2024-05-20 |
AU2015256082A1 (en) | 2016-10-06 |
US20170182253A1 (en) | 2017-06-29 |
IL247935B (en) | 2020-08-31 |
KR102496507B1 (ko) | 2023-02-03 |
SG11201609219QA (en) | 2016-12-29 |
BR112016025852B1 (pt) | 2022-11-01 |
IL247935A0 (en) | 2016-11-30 |
US10722655B2 (en) | 2020-07-28 |
EP3785749A1 (en) | 2021-03-03 |
CN106413779A (zh) | 2017-02-15 |
BR112016025852A2 (pt) | 2017-10-17 |
CA2945026A1 (en) | 2015-11-12 |
JP2020072938A (ja) | 2020-05-14 |
CN106413779B (zh) | 2020-06-05 |
JP7123898B2 (ja) | 2022-08-23 |
AU2015256082C1 (en) | 2020-09-10 |
JP2022101692A (ja) | 2022-07-06 |
AU2015256082B2 (en) | 2020-02-27 |
JP2017518791A (ja) | 2017-07-13 |
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