HUP0102429A2 - Baromfipestis-vírus fertőző klónjai, vakcinák és diagnosztikai eljárások - Google Patents

Baromfipestis-vírus fertőző klónjai, vakcinák és diagnosztikai eljárások

Info

Publication number
HUP0102429A2
HUP0102429A2 HU0102429A HUP0102429A HUP0102429A2 HU P0102429 A2 HUP0102429 A2 HU P0102429A2 HU 0102429 A HU0102429 A HU 0102429A HU P0102429 A HUP0102429 A HU P0102429A HU P0102429 A2 HUP0102429 A2 HU P0102429A2
Authority
HU
Hungary
Prior art keywords
ndv
vaccines
vaccine
cdnas
enables
Prior art date
Application number
HU0102429A
Other languages
English (en)
Inventor
Leeuw Olav Sven De
Arnoud Leonard Josef Gielkens
Guus Koch
Bernardus Petrus Hubertus Peeters
Original Assignee
Id-Lelystad, Instituut Voor Dierhouderij En Diergezondheid B.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8233832&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP0102429(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Id-Lelystad, Instituut Voor Dierhouderij En Diergezondheid B.V. filed Critical Id-Lelystad, Instituut Voor Dierhouderij En Diergezondheid B.V.
Publication of HUP0102429A2 publication Critical patent/HUP0102429A2/hu
Publication of HUP0102429A3 publication Critical patent/HUP0102429A3/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18111Avulavirus, e.g. Newcastle disease virus
    • C12N2760/18122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18111Avulavirus, e.g. Newcastle disease virus
    • C12N2760/18141Use of virus, viral particle or viral elements as a vector
    • C12N2760/18143Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Abstract

Above=66;>(57) A találmány tárgyát szárnyasok baromfipestisét okozóvírusok képezik, közelebbről madár-paramyxovírusból származó cDNS-ek,továbbá a találmány szerinti cDNS-ekből előállítható RNS, valaminteljárások madár-paramyxovírus fertőző kópiájának előállítására. Atalálmány tárgyát képezi továbbá a találmány szerinti eljárássalelőállított fertőző madár-paramyxovírus, az ilyen vírust tartalmazóvakcina, továbbá eljárás a találmány szerinti vakcinával vakcináltállatok baromfipestis-vírussal (NDV) fertőzött vagy módosítatlan NDV-vakcinával vakcinált állatoktól történő megkülönböztetésére, valamintdiagnosztikai reagenskészlet az ilyen eljárásban történő alkalmazásra.A találmány szerinti eljárás lehetőséget biztosít az NDV-genomgenetikai módosítással történő megváltoztatására, ezáltal az NDVvirulenciájának módosítására, ami javított tulajdonságú, legyengítettélő vakcinák előállítását teszi lehetővé. A találmány szerinti eljáráselőnyösen alkalmazható az NDV antigénes kiegészítésére, ami olyan élőNDV3 markervakcinák létrehozását teszi lehetővé, amelyekszerológiailag megkülönböztethetők a vad NDV-törzsektől. Ó
HU0102429A 1998-06-19 1999-06-17 Newcastle disease virus infectious clones, vaccines and diagnostic assays HUP0102429A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98202054A EP0974660A1 (en) 1998-06-19 1998-06-19 Newcastle disease virus infectious clones, vaccines and diagnostic assays
PCT/NL1999/000377 WO1999066045A1 (en) 1998-06-19 1999-06-17 Newcastle disease virus infectious clones, vaccines and diagnostic assays

Publications (2)

Publication Number Publication Date
HUP0102429A2 true HUP0102429A2 (hu) 2001-10-28
HUP0102429A3 HUP0102429A3 (en) 2003-12-29

Family

ID=8233832

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0102429A HUP0102429A3 (en) 1998-06-19 1999-06-17 Newcastle disease virus infectious clones, vaccines and diagnostic assays

Country Status (28)

Country Link
US (3) US6719979B2 (hu)
EP (2) EP0974660A1 (hu)
JP (3) JP2002518012A (hu)
KR (1) KR20010053000A (hu)
CN (2) CN1314942A (hu)
AR (1) AR020091A1 (hu)
AT (1) ATE367442T1 (hu)
AU (1) AU754844B2 (hu)
BR (1) BR9911383A (hu)
CA (1) CA2334165A1 (hu)
CZ (1) CZ300760B6 (hu)
DE (1) DE69936585T2 (hu)
DK (1) DK1088077T3 (hu)
EA (1) EA004796B1 (hu)
ES (1) ES2291029T3 (hu)
HR (1) HRP20010042B1 (hu)
HU (1) HUP0102429A3 (hu)
ID (1) ID27343A (hu)
IL (2) IL140381A0 (hu)
NO (1) NO329193B1 (hu)
NZ (1) NZ508982A (hu)
PL (1) PL197722B1 (hu)
PT (1) PT1088077E (hu)
SI (1) SI1088077T1 (hu)
TR (1) TR200100350T2 (hu)
UA (1) UA77146C2 (hu)
WO (1) WO1999066045A1 (hu)
ZA (1) ZA200100241B (hu)

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0974660A1 (en) 1998-06-19 2000-01-26 Stichting Instituut voor Dierhouderij en Diergezondheid (ID-DLO) Newcastle disease virus infectious clones, vaccines and diagnostic assays
US6146642A (en) * 1998-09-14 2000-11-14 Mount Sinai School Of Medicine, Of The City University Of New York Recombinant new castle disease virus RNA expression systems and vaccines
US10383936B2 (en) * 1999-05-05 2019-08-20 University Of Maryland, College Park Infectious laryngotracheitis virus (ILTV) vaccine using recombinant newcastle disease virus vector
AU4971500A (en) * 1999-05-05 2000-11-21 University Of Maryland Production of novel newcastle disease virus strains from cdnas and improved liveattenuated newcastle disease vaccines
EP1074614B1 (en) * 1999-07-27 2004-07-07 Akzo Nobel N.V. A recombinant Newcastle disease virus for in ovo vaccination
CA2312626A1 (en) 1999-07-27 2001-01-27 Akzo Nobel N.V. A recombinant newcastle disease virus as an embryo vaccine
DE60139319D1 (en) 2000-06-23 2009-09-03 Intervet Int Bv Us
PT1383795E (pt) 2000-11-02 2007-04-30 Intervet Int Bv Mutante da nucleoproteína do vírus da doença de newcastle recombinante como vacina marcadora
KR100437888B1 (ko) * 2001-07-30 2004-07-03 주식회사 인트론바이오테크놀로지 뉴캐슬병 바이러스 검출용 프라이머 및 상기 프라이머를이용한 뉴캐슬병 바이러스 검출, 병원성 및 유전형 조사방법
IL145397A0 (en) * 2001-09-12 2002-06-30 Yissum Res Dev Co Compositions and methods for treatment of cancer
US7615209B2 (en) 2001-09-12 2009-11-10 Yissum Research Development Company Of The Hebrew University Of Jerusalem Compositions of NDV and methods of use thereof for treatment of cancer
ATE307606T1 (de) * 2001-10-04 2005-11-15 Ct Voor Onderzoek In Diergenee Abgeschwächter mutantenstamm eines virus der newcastle-krankheit für eine in ovo impfung und dessen benutzung
US8709442B2 (en) * 2002-02-21 2014-04-29 Icahn School Of Medicine At Mount Sinai Recombinant negative strand virus RNA expression systems and vaccines
TW200502402A (en) * 2002-12-06 2005-01-16 Wyeth Corp Escape mutants of newcastle disease virus as marker vaccines
US20040268442A1 (en) * 2003-05-05 2004-12-30 Dow Agrosciences Llc Stable immunoprophylactic and therapeutic compositions derived from transgenic plant cells and methods for production
NZ543348A (en) * 2003-05-05 2008-08-29 Thompson Boyce Plant Res Vectors and cells for preparing immunoprotective compositions derived from transgenic plants
ATE478137T1 (de) 2003-06-20 2010-09-15 Microbix Biosystems Inc Verbesserungen bei der virusproduktion
US7527638B2 (en) 2003-12-16 2009-05-05 Depuy Spine, Inc. Methods and devices for minimally invasive spinal fixation element placement
MY146476A (en) 2004-06-24 2012-08-15 Boehringer Ingelheim Vetmed Method of diagnosing lawsonia intracellularis
GB0423681D0 (en) * 2004-10-26 2004-11-24 Sec Dep For Environment Food & Vaccine and nucleic acids
NZ585895A (en) 2004-11-12 2011-05-27 Bayer Schering Pharma Ag Recombinant newcastle disease virus comprising a transgene encoding a fusion protein comprising a binding domain and a heterologous domain comprising a toxin
US7871626B2 (en) 2005-08-04 2011-01-18 St. Jude Children's Research Hospital Modified influenza virus for monitoring and improving vaccine efficiency
US9216212B2 (en) 2005-08-05 2015-12-22 University Of Massachusetts Virus-like particles as vaccines for paramyxovirus
US7951384B2 (en) * 2005-08-05 2011-05-31 University Of Massachusetts Virus-like particles as vaccines for paramyxovirus
PL2251034T3 (pl) * 2005-12-02 2018-07-31 Icahn School Of Medicine At Mount Sinai Chimeryczne wirusy prezentujące nienatywne białka powierzchniowe i zastosowania tych wirusów
AU2007224430A1 (en) * 2006-03-15 2007-09-20 Intervet International B.V. Recombinant Newcastle disease virus expressing H5 hemagglutinin of avian influenza virus
CA2638746C (en) * 2006-03-15 2014-12-02 Intervet International B.V. Recombinant mononegaviral virus vectors
KR100776398B1 (ko) * 2006-03-23 2007-11-28 주식회사 고려비엔피 조류 hn 단백질의 에피토프 및 상기 변이 에피토프를포함하는 뉴캐슬병 바이러스
KR100801180B1 (ko) * 2006-09-26 2008-02-05 주식회사 고려비엔피 약독화된 재조합 뉴캐슬병 바이러스 및 이를 함유하는뉴캐슬병 백신
KR100874256B1 (ko) 2007-02-12 2008-12-16 대한민국 대장균 내독소 단백질 및 뉴캐슬병 바이러스뉴라미니데이즈 에피토프의 융합단백질 및 이의 용도
KR100955502B1 (ko) * 2007-11-30 2010-04-30 대한민국 병원성 뉴캐슬병 바이러스 항체와 특이적으로 반응하는펩타이드 및 그의 용도
EP2085092A1 (en) 2008-01-29 2009-08-05 Bayer Schering Pharma Aktiengesellschaft Attenuated oncolytic paramyxoviruses encoding avian cytokines
US7794714B2 (en) * 2008-03-14 2010-09-14 The United States Of America As Represented By The Secretary Of Agriculture Newcastle disease virus monoclonal antibodies
US20090258035A1 (en) * 2008-03-21 2009-10-15 The United States Of America, As Represented By The Secretary Of Agriculture Avian virus vaccines and uses thereof
CN102281896A (zh) * 2008-11-19 2011-12-14 阿维-梅克斯实验室公司 重组失活病毒载体疫苗
WO2010091262A1 (en) 2009-02-05 2010-08-12 Mount Sinai School Of Medicine Of New York University Chimeric newcastle disease viruses and uses thereof
CA2771540C (en) * 2009-08-21 2019-01-15 Merial Limited Recombinant avian paramyxovirus vaccine and method for making and using thereof
US20110110975A1 (en) * 2009-11-06 2011-05-12 Streck, Inc. Inactivated virus compositions and methods of preparing such compositions
ATE539148T1 (de) 2009-11-30 2012-01-15 United Cancer Res Inst Neuer klon des geflügelpestvirus, herstellung und anwendung bei der medizinischen behandlung von krebs
WO2012151391A2 (en) 2011-05-04 2012-11-08 Streck, Inc. Inactivated virus compositions and methods of preparing such compositions
EP2797613B1 (en) 2011-10-27 2019-12-04 Wellstat Ophthalmics Corporation Vectors encoding rod-derived cone viability factor
ES2719409T5 (es) 2011-11-30 2022-12-07 Boehringer Ingelheim Animal Health Usa Inc Vectores recombinantes de Gallid herpesvirus 3 (mdv serotipo 2) que expresan antígenos de patógenos aviares y usos de los mismos
KR101374192B1 (ko) * 2011-12-21 2014-03-14 대한민국 제4형 조류파라믹소바이러스 hn 단백질 및 이를 포함하는 hi법 검사용 항원진단액
BR112015021414B1 (pt) 2013-03-14 2020-11-10 Icahn School Of Medicine At Mount Sinai vírus da doença newcastle e seus usos
CN104059942B (zh) * 2013-03-20 2016-12-28 湖北省农业科学院畜牧兽医研究所 新城疫病毒耐热活疫苗载体系统及其应用
US20140341950A1 (en) * 2013-05-15 2014-11-20 University Of Georgia Research Foundation, Inc. Recombinant avian paramyxovirus vaccine and method for making and using thereof
SG11201607130RA (en) 2014-02-27 2016-09-29 Viralytics Ltd Combination method for treatment of cancer
US10780158B2 (en) 2015-11-16 2020-09-22 Georgia State University Research Foundation, Inc. Tunable vaccine platform against pathogens of the paramyxovirus family
JP2019506168A (ja) 2016-02-03 2019-03-07 シージー ディスカバリー インコーポレイテッドCg Discovery, Inc. 異種エピトープ及び/又は改変された成熟切断部位を有するインフルエンザヘマグルチニンの組成物
US10063211B2 (en) * 2016-02-03 2018-08-28 Qualcomm Incorporated Compact bypass and decoupling structure for millimeter-wave circuits
US10196616B2 (en) 2017-02-15 2019-02-05 The United States Of America, As Represented By The Secretary Of Agriculture Altered avian virus for in-ovo inoculation and methods of use thereof
MX2020008988A (es) * 2018-02-28 2020-09-28 Regeneron Pharma Sistemas y metodos para la identificacion de contaminantes virales.
CA3106170A1 (en) * 2018-07-13 2020-01-16 Icahn School Of Medicine At Mount Sinai Apmv and uses thereof for the treatment of cancer
CN109735552A (zh) * 2019-02-27 2019-05-10 苏州世诺生物技术有限公司 禽新城疫病毒新型基因工程亚单位疫苗
CN110018304A (zh) * 2019-05-15 2019-07-16 河南省农业科学院 一种新城疫抗体阻断检测试纸
CN110240635B (zh) * 2019-06-10 2022-04-22 华中农业大学 检测新城疫病毒抗体的多肽及其elisa检测试剂盒
CN110257562A (zh) * 2019-07-31 2019-09-20 河北农业大学 一种raa-lfd检测鸡传染性喉气管炎病毒的引物和探针组合及其应用
KR102154796B1 (ko) * 2019-10-18 2020-09-22 주식회사 바이오포아 변이 뉴캣슬병 바이러스 및 상기 바이러스를 이용한 조류 백신
CN110938711A (zh) * 2019-12-20 2020-03-31 河北农业大学 一种检测鸡传染性喉气管炎病毒的实时荧光raa引物和探针、试剂盒及其使用方法
CN111334528B (zh) * 2020-03-20 2022-02-18 山东农业大学 水貂肠炎细小病毒全基因组感染性克隆及其构建方法和应用
CN112048484A (zh) * 2020-07-27 2020-12-08 华南农业大学 一株表达传染性法氏囊强毒株vp2蛋白的基因ⅶ型新城疫重组病毒和疫苗
CN114214338B (zh) * 2021-08-26 2023-02-03 扬州大学 猪源piv5全长感染性克隆及其制备方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU602875B2 (en) * 1985-12-18 1990-11-01 British Technology Group Limited Newcastle disease virus gene clones
ES2210273T5 (es) 1994-07-18 2010-03-29 Conzelmann, Karl-Klaus, Prof. Dr. Virus con arn de cadena negativa no segmentado recombinante infeccioso.
WO1996040880A1 (en) * 1995-06-07 1996-12-19 Syntro Corporation Recombinant fowlpox viruses and uses thereof
DE69510207T3 (de) * 1995-08-09 2007-02-15 Schweiz. Serum- & Impfinstitut Bern Verfahren zur Herstellung von infektiösen minussträngigen RNA-Viren
EP0839912A1 (en) * 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
EP0974660A1 (en) 1998-06-19 2000-01-26 Stichting Instituut voor Dierhouderij en Diergezondheid (ID-DLO) Newcastle disease virus infectious clones, vaccines and diagnostic assays
US6146642A (en) 1998-09-14 2000-11-14 Mount Sinai School Of Medicine, Of The City University Of New York Recombinant new castle disease virus RNA expression systems and vaccines

Also Published As

Publication number Publication date
JP2006141398A (ja) 2006-06-08
DE69936585D1 (de) 2007-08-30
IL140381A0 (en) 2002-02-10
EP1088077B1 (en) 2007-07-18
BR9911383A (pt) 2001-03-13
NO329193B1 (no) 2010-09-13
PL348300A1 (en) 2002-05-20
EP0974660A1 (en) 2000-01-26
US7547442B2 (en) 2009-06-16
EA200100057A1 (ru) 2001-08-27
CN101275142A (zh) 2008-10-01
EP1088077A1 (en) 2001-04-04
DK1088077T3 (da) 2007-11-12
EP1088077B2 (en) 2012-03-21
PT1088077E (pt) 2007-10-29
CZ300760B6 (cs) 2009-08-05
CN1314942A (zh) 2001-09-26
IL140381A (en) 2008-06-05
US20040235134A1 (en) 2004-11-25
US6719979B2 (en) 2004-04-13
US20030087417A1 (en) 2003-05-08
HRP20010042A2 (en) 2001-12-31
CZ20004707A3 (en) 2001-05-16
ZA200100241B (en) 2002-06-26
AU4399199A (en) 2000-01-05
UA77146C2 (en) 2006-11-15
ES2291029T3 (es) 2008-02-16
HUP0102429A3 (en) 2003-12-29
NZ508982A (en) 2003-07-25
EA004796B1 (ru) 2004-08-26
AR020091A1 (es) 2002-04-10
ID27343A (id) 2001-04-05
US7332169B2 (en) 2008-02-19
TR200100350T2 (tr) 2001-06-21
PL197722B1 (pl) 2008-04-30
SI1088077T1 (sl) 2008-02-29
NO20006406L (no) 2001-02-19
ATE367442T1 (de) 2007-08-15
WO1999066045A1 (en) 1999-12-23
US20040234552A1 (en) 2004-11-25
NO20006406D0 (no) 2000-12-15
JP2009261387A (ja) 2009-11-12
DE69936585T2 (de) 2008-04-30
JP2002518012A (ja) 2002-06-25
KR20010053000A (ko) 2001-06-25
AU754844B2 (en) 2002-11-28
CA2334165A1 (en) 1999-12-23
HRP20010042B1 (en) 2011-03-31

Similar Documents

Publication Publication Date Title
HUP0102429A2 (hu) Baromfipestis-vírus fertőző klónjai, vakcinák és diagnosztikai eljárások
Gohm et al. Detection of Newcastle disease virus in organs and faeces of experimentally infected chickens using RT-PCR
Lee et al. Effect of vaccine use in the evolution of Mexican lineage H5N2 avian influenza virus
Ignjatovic et al. Isolation of a variant infectious bronchitis virus in Australia that further illustrates diversity among emerging strains
EP0891420A1 (en) Processes for the replication of influenza viruses in cell culture, and the influenza viruses obtainable by the process
Abdel-Alim et al. Immunogenicity and antigenicity of very virulent strains of infectious bursal disease viruses
Chen et al. Molecular and antigenic characteristics of Massachusetts genotype infectious bronchitis coronavirus in China
Zhou et al. Establishment of reverse genetics system for infectious bronchitis virus attenuated vaccine strain H120
AU741055B2 (en) A method for generating birnavirus from synthetic RNA transcripts
DE3775321D1 (de) Verfahren zur kultur des virus der rhinotracheitis des truthahnes und daraus hergestelltes vakzin.
CN104232594A (zh) 重组类禽型h1n1流感病毒灭活疫苗株(js40/pr8)及其制备方法和应用
Mayahi et al. Characterization of isolated pigeon paramyxovirus-1 (PMV-1) and its pathogenicity in broiler chickens
Zhou et al. Characterization of an avian infectious bronchitis virus isolated in China from chickens with nephritis
Mahamud et al. Efficacy of genotype-matched Newcastle disease virus vaccine formulated in carboxymethyl sago starch acid hydrogel in chickens vaccinated via different routes
CN111763659B (zh) 新型冠状病毒及其培养方法,以及新型冠状病毒灭活疫苗
Ball et al. Infectious bronchitis vaccine virus detection and part-S1 genetic variation following single or dual inoculation in broiler chicks
Ashraf et al. Interference between mild and pathogenic strains of infectious bursal disease virus in chickens
Kaye et al. Antigenic relationship between human coronavirus strain DC 43 and hemagglutinating encephalomyelitis virus strain 67N of swine: antibody responses in human and animal sera
Lv et al. Construction of an infectious bronchitis virus vaccine strain carrying chimeric S1 gene of a virulent isolate and its pathogenicity analysis
Liu et al. Adaptation of a Chinese ferret badger strain of rabies virus to high-titered growth in BHK-21 cells for canine vaccine development
Habib et al. Immunogenicity of formaldehyde and binary ethylenimine inactivated infectious bursal disease virus in broiler chicks
Estevez et al. A recombination event, induced in ovo, between a low passage infectious bronchitis virus field isolate and a highly embryo adapted vaccine strain
Kovács et al. Identification of the main genetic clusters of avian reoviruses from a global strain collection
US4206287A (en) Vaccines and their preparation
RU2084525C1 (ru) Аттенуированный холодоадаптированный штамм вируса гриппа в ссср(69)е для получения живой интраназальной гриппозной вакцины

Legal Events

Date Code Title Description
GB9A Succession in title

Owner name: STICHTIG DIENST LANDBOUWKUNDIG ONDERZOEK, NL

Free format text: FORMER OWNER(S): ID-LELYSTAD, INSTITUUT VOOR DIERHOUDERIJ EN DIERGEZONDHEID B.V., NL

GB9A Succession in title

Owner name: STICHTING DIENST LANDBOUWKUNDIG ONDERZOEK, NL

Free format text: FORMER OWNER(S): ID-LELYSTAD, INSTITUUT VOOR DIERHOUDERIJ EN DIERGEZONDHEID B.V., NL; ID-LELYSTAD, INSTITUUT VOOR DIERHOUDERIJ EN DIERGEZONDHEID B.V., NL; STICHTIG DIENST LANDBOUWKUNDIG ONDERZOEK, NL

FA9A Lapse of provisional patent protection due to relinquishment or protection considered relinquished