AR020091A1 - Adnc de paramyxovirus aviar (particularmente virus de la enfermedad de newcastle), arn, metodo para generar copias de virus infeccioso de paramyxovirusaviar, copia de virus infeccioso, vacuna que comprende dicho virus, vacuna viva, metodo para distinguir animales no vacunados o animales vacunados, y - Google Patents

Adnc de paramyxovirus aviar (particularmente virus de la enfermedad de newcastle), arn, metodo para generar copias de virus infeccioso de paramyxovirusaviar, copia de virus infeccioso, vacuna que comprende dicho virus, vacuna viva, metodo para distinguir animales no vacunados o animales vacunados, y

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Publication number
AR020091A1
AR020091A1 ARP990102948A ARP990102948A AR020091A1 AR 020091 A1 AR020091 A1 AR 020091A1 AR P990102948 A ARP990102948 A AR P990102948A AR P990102948 A ARP990102948 A AR P990102948A AR 020091 A1 AR020091 A1 AR 020091A1
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virus
vaccines
vaccine
ndv
cdna
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ARP990102948A
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Stichting Dienst Landbouwkundi
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Application filed by Stichting Dienst Landbouwkundi filed Critical Stichting Dienst Landbouwkundi
Publication of AR020091A1 publication Critical patent/AR020091A1/es

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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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    • C07ORGANIC CHEMISTRY
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    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18111Avulavirus, e.g. Newcastle disease virus
    • C12N2760/18122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18111Avulavirus, e.g. Newcastle disease virus
    • C12N2760/18141Use of virus, viral particle or viral elements as a vector
    • C12N2760/18143Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

ADNc de paramyxovirus aviar que contiene por lo menos una secuencia de ácido nucleico correspondiente al extremo terminal 5 del genoma del paramyxovirusaviar y que permite generar un minigenoma replicante de paramyxovirus aviar particularmente permite generar una copia infecciosa de paramyxovirus aviar,particularmente a partir de un ADNc de longitud total . Proceso para generar virus infeccioso de la Enfermedad de Newcastle (NDV) totalmente a partir de ADNcclonado de longitud total, y uso de vacunas y pruebas de diagnostico generadas con dicho proceso y derivadas del mismo. El proceso ofrece la posibilidad demodificar el genoma del NDV por medio de la modificacion genética y da lugar a la introduccion de mutaciones, delecciones y/o inserciones. Este proceso sepuede emplear para modificar la virulencia de NDV, generando así vacunas vivas atenuadas con propiedades mejoradas. Este proceso se puede usar para modificarla constitucion genética del NDV, permitiendo de esta manera la generacion de vacunas marcadoras vivas del NDV que se pueden distinguir serologicamente de lascepas de campo del NDV. Copia de virus infeccioso, vacuna que comprende dicho virus, vacuna viva, método para distinguir animales no vacunados o animalesvacunados ykit de diagnostico.
ARP990102948A 1998-06-19 1999-06-18 Adnc de paramyxovirus aviar (particularmente virus de la enfermedad de newcastle), arn, metodo para generar copias de virus infeccioso de paramyxovirusaviar, copia de virus infeccioso, vacuna que comprende dicho virus, vacuna viva, metodo para distinguir animales no vacunados o animales vacunados, y AR020091A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98202054A EP0974660A1 (en) 1998-06-19 1998-06-19 Newcastle disease virus infectious clones, vaccines and diagnostic assays

Publications (1)

Publication Number Publication Date
AR020091A1 true AR020091A1 (es) 2002-04-10

Family

ID=8233832

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP990102948A AR020091A1 (es) 1998-06-19 1999-06-18 Adnc de paramyxovirus aviar (particularmente virus de la enfermedad de newcastle), arn, metodo para generar copias de virus infeccioso de paramyxovirusaviar, copia de virus infeccioso, vacuna que comprende dicho virus, vacuna viva, metodo para distinguir animales no vacunados o animales vacunados, y

Country Status (28)

Country Link
US (3) US6719979B2 (es)
EP (2) EP0974660A1 (es)
JP (3) JP2002518012A (es)
KR (1) KR20010053000A (es)
CN (2) CN1314942A (es)
AR (1) AR020091A1 (es)
AT (1) ATE367442T1 (es)
AU (1) AU754844B2 (es)
BR (1) BR9911383A (es)
CA (1) CA2334165A1 (es)
CZ (1) CZ300760B6 (es)
DE (1) DE69936585T2 (es)
DK (1) DK1088077T3 (es)
EA (1) EA004796B1 (es)
ES (1) ES2291029T3 (es)
HR (1) HRP20010042B1 (es)
HU (1) HUP0102429A3 (es)
ID (1) ID27343A (es)
IL (2) IL140381A0 (es)
NO (1) NO329193B1 (es)
NZ (1) NZ508982A (es)
PL (1) PL197722B1 (es)
PT (1) PT1088077E (es)
SI (1) SI1088077T1 (es)
TR (1) TR200100350T2 (es)
UA (1) UA77146C2 (es)
WO (1) WO1999066045A1 (es)
ZA (1) ZA200100241B (es)

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JP2006141398A (ja) 2006-06-08
DE69936585D1 (de) 2007-08-30
IL140381A0 (en) 2002-02-10
EP1088077B1 (en) 2007-07-18
BR9911383A (pt) 2001-03-13
NO329193B1 (no) 2010-09-13
PL348300A1 (en) 2002-05-20
EP0974660A1 (en) 2000-01-26
US7547442B2 (en) 2009-06-16
EA200100057A1 (ru) 2001-08-27
CN101275142A (zh) 2008-10-01
EP1088077A1 (en) 2001-04-04
DK1088077T3 (da) 2007-11-12
EP1088077B2 (en) 2012-03-21
PT1088077E (pt) 2007-10-29
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