AR019250A1 - Formas atenuadas del virus de la diarrea viral bovina, molecula de acido nucleico, vector, uso, metodo para modificar el genoma viral de tipo salvaje, genoma modificado, vacuna, metodo para atenuar un virus bvd de tipo salvaje - Google Patents

Formas atenuadas del virus de la diarrea viral bovina, molecula de acido nucleico, vector, uso, metodo para modificar el genoma viral de tipo salvaje, genoma modificado, vacuna, metodo para atenuar un virus bvd de tipo salvaje

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Publication number
AR019250A1
AR019250A1 ARP990105650A ARP990105650A AR019250A1 AR 019250 A1 AR019250 A1 AR 019250A1 AR P990105650 A ARP990105650 A AR P990105650A AR P990105650 A ARP990105650 A AR P990105650A AR 019250 A1 AR019250 A1 AR 019250A1
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AR
Argentina
Prior art keywords
virus
genome
wild
diarrea
denim
Prior art date
Application number
ARP990105650A
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English (en)
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Pfizer Prod Inc
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Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of AR019250A1 publication Critical patent/AR019250A1/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24361—Methods of inactivation or attenuation

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invencion se refiere a un método para producir formas atenuadas de virus de la diarrea viral bovina (BVD) mutando el gen de proteasaN(pro). La invencion incluye los virus atenuados preparados por este método, los anticuerpos creadosutili zando estos virus y las vacunas que se puedenutilizar para inmunizar ganado vacuno.
ARP990105650A 1998-11-10 1999-11-08 Formas atenuadas del virus de la diarrea viral bovina, molecula de acido nucleico, vector, uso, metodo para modificar el genoma viral de tipo salvaje, genoma modificado, vacuna, metodo para atenuar un virus bvd de tipo salvaje AR019250A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10790898P 1998-11-10 1998-11-10

Publications (1)

Publication Number Publication Date
AR019250A1 true AR019250A1 (es) 2001-12-26

Family

ID=22319107

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP990105650A AR019250A1 (es) 1998-11-10 1999-11-08 Formas atenuadas del virus de la diarrea viral bovina, molecula de acido nucleico, vector, uso, metodo para modificar el genoma viral de tipo salvaje, genoma modificado, vacuna, metodo para atenuar un virus bvd de tipo salvaje

Country Status (12)

Country Link
US (4) US6168942B1 (es)
EP (1) EP1013757A3 (es)
JP (2) JP3602759B2 (es)
CN (2) CN1247775C (es)
AR (1) AR019250A1 (es)
AU (1) AU765792B2 (es)
BR (1) BR9905352A (es)
CA (1) CA2287775A1 (es)
HK (2) HK1026718A1 (es)
NZ (1) NZ500925A (es)
TW (1) TW585916B (es)
ZA (1) ZA997011B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7179473B2 (en) 1998-06-05 2007-02-20 Boehringer Ingelheim Vetmedica Gmbh Attenuated pestiviruses
EP1035205A1 (en) * 1999-03-08 2000-09-13 Stichting Dienst Landbouwkundig Onderzoek Non-spreading pestivirus
US7135561B2 (en) 2001-09-06 2006-11-14 Boehringer Ingelheim Vetmedica Gmbh Infectious bovine viral diarrhea virus clone
US20040229224A1 (en) * 2003-05-13 2004-11-18 Perlegen Sciences, Inc. Allele-specific expression patterns
US7572455B2 (en) 2004-05-19 2009-08-11 Boehringer Ingelheim Vetmedica Gmbh Vaccine comprising an attenuated pestivirus
DE102004025452A1 (de) * 2004-05-19 2006-01-19 Boehringer Ingelheim Vetmedica Gmbh Vakzine enthaltend BVDV
UY29915A1 (es) * 2005-11-15 2007-06-29 Boehringer Ingelheim Vetmed Vacuna combinada que comprende un virus atenuado de la diarrea viral bovina
KR101045165B1 (ko) * 2005-12-07 2011-06-30 화이자 프로덕츠 인크. 마킹된 소 바이러스성 설사 바이러스 백신
AR062917A1 (es) 2006-09-22 2008-12-17 Intervet Int Bv Nuevo mutante de pestivirus para uso en una vacuna.
EP2130912A1 (en) * 2008-06-04 2009-12-09 Institut für Viruskrankeiten und Immunprophylaxe Pestivirus replicons providing an RNA-based viral vector system
UY31930A (es) * 2008-06-25 2010-01-29 Boheringer Ingelheim Pharma Kg Pestivirus atenuados recombinantes, en particular a csfv, bvdv o bdv atenuado recombinante
US8846054B2 (en) * 2009-01-09 2014-09-30 Boehringer Ingelheim Vetmedica, Inc. Method of treating pregnant cows and/or heifers
WO2012038454A1 (en) 2010-09-21 2012-03-29 Intervet International B.V. Bvdv vaccine
RU2502522C1 (ru) * 2012-07-27 2013-12-27 Государственное научное учреждение Всероссийский научно-исследовательский институт ветеринарной санитарии, гигиены и экологии Российской академии сельскохозяйственных наук Способ получения вакцины против вирусной диареи крупного рогатого скота
CN113174374B (zh) * 2021-05-19 2022-07-22 西南民族大学 一种牛病毒性腹泻病毒弱毒株及其用途
CN113403256B (zh) * 2021-06-16 2023-04-18 中国农业科学院特产研究所 一种稳定产生牛病毒性腹泻病毒抗原的细胞系及抗体胶体金检测试纸条的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA864879B (en) 1985-07-08 1987-03-25 Wallone Region Vaccines and diagnostics derived from boving diarrhoea virus
US5206163A (en) * 1985-07-08 1993-04-27 Chiron Corporation DNA encoding bovine diarrhea virus protein
FR2677767B1 (fr) 1991-06-11 1994-10-14 Biotechnologie Ste Europeenne Procede de detection de l'infection par le virus de la diarrhee bovine, sequence nucleotidique codant pour une proteine induite par l'infection par ce virus et proteines et antigenes recombinants s'y rapportant .
EP1104676A1 (en) 1999-11-30 2001-06-06 Boehringer Ingelheim Vetmedica Gmbh Safe attenuated bovine viral diarrhea viruses for use in pregnant cows

Also Published As

Publication number Publication date
JP3602841B2 (ja) 2004-12-15
NZ500925A (en) 2001-06-29
HK1067383A1 (en) 2005-04-08
EP1013757A2 (en) 2000-06-28
AU765792B2 (en) 2003-10-02
JP2003259885A (ja) 2003-09-16
US6168942B1 (en) 2001-01-02
US6410032B1 (en) 2002-06-25
JP3602759B2 (ja) 2004-12-15
CN1510130A (zh) 2004-07-07
US6916477B2 (en) 2005-07-12
EP1013757A3 (en) 2002-03-06
CA2287775A1 (en) 2000-05-10
HK1026718A1 (en) 2000-12-22
CN1247775C (zh) 2006-03-29
US6410299B1 (en) 2002-06-25
AU5837699A (en) 2000-05-11
CN1254756A (zh) 2000-05-31
US20030165520A1 (en) 2003-09-04
ZA997011B (en) 2001-05-09
CN1231578C (zh) 2005-12-14
JP2000139482A (ja) 2000-05-23
BR9905352A (pt) 2001-02-06
TW585916B (en) 2004-05-01

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