YU17891A - Dnk koja odgovara genomu virusa sa negativnim lancem rnk, i postupak za dobijanje infektivnih virusa sa negativnim lancem rnk - Google Patents

Dnk koja odgovara genomu virusa sa negativnim lancem rnk, i postupak za dobijanje infektivnih virusa sa negativnim lancem rnk

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Publication number
YU17891A
YU17891A YU17891A YU17891A YU17891A YU 17891 A YU17891 A YU 17891A YU 17891 A YU17891 A YU 17891A YU 17891 A YU17891 A YU 17891A YU 17891 A YU17891 A YU 17891A
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Yugoslavia
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negative
rna
strand
viruses
chain
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YU17891A
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English (en)
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A.M. Ballart
R. Cattaneo
A. Schmid
I. Ballart
D. Eschle
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Schweiz Serum-& Impfinstitut Bern
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Publication of YU17891A publication Critical patent/YU17891A/sh

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    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18411—Morbillivirus, e.g. Measles virus, canine distemper
    • C12N2760/18421—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18411—Morbillivirus, e.g. Measles virus, canine distemper
    • C12N2760/18422—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18411—Morbillivirus, e.g. Measles virus, canine distemper
    • C12N2760/18441—Use of virus, viral particle or viral elements as a vector
    • C12N2760/18443—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/20011—Rhabdoviridae
    • C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
    • C12N2760/20222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

DNK KOJA ODGOVARA GENOMU VIRUSA SA NEGATIVNIM LANCEM RNK, I POSTUPAK ZA DOBIJANJE INFEKTIVNIH VIRUSA SA NEGATIVNIM LANCEM RNK, sadašnji pronalazak se, u načelu, odnosi na metodologiju pogodnu za dobijanje infektivnih virusa sa negativnim lancem, korisnih za upotrebu u vakcinama, iz klonirane komplementarne dezoksiribonukleinske kiseline (cDNK). Pronalazak se konkretno odnosi na molekule cDNK i na pomoćne ćelije koje su korisne kao orudje u ovoj metodologiji, kao i na karakterizaciju dobijenih virusa. Kao model za RNK-viruse sa negativnim lancem korišćen je virus malih boginja (MV). Opisani pronalazak obezbedjuje tehnologiju za konstruisanje rekombinantnih vakcinskih sojeva MV koji kodiraju epitope ili kompletne proteine iz heterolognih virusa, bakterija ili parazita. Uz male modifikacije opisane tehnologije kao vektor, umesto MV, može da se koristi bilo koji RNK-virus sa negativnim lancem.
YU17891A 1990-02-02 1991-02-01 Dnk koja odgovara genomu virusa sa negativnim lancem rnk, i postupak za dobijanje infektivnih virusa sa negativnim lancem rnk YU17891A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP90102120 1990-02-02

Publications (1)

Publication Number Publication Date
YU17891A true YU17891A (sh) 1994-09-09

Family

ID=8203580

Family Applications (1)

Application Number Title Priority Date Filing Date
YU17891A YU17891A (sh) 1990-02-02 1991-02-01 Dnk koja odgovara genomu virusa sa negativnim lancem rnk, i postupak za dobijanje infektivnih virusa sa negativnim lancem rnk

Country Status (5)

Country Link
EP (1) EP0440219A1 (sh)
JP (1) JPH04211377A (sh)
AU (1) AU7007491A (sh)
CA (1) CA2035386A1 (sh)
YU (1) YU17891A (sh)

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Also Published As

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CA2035386A1 (en) 1991-08-03
AU7007491A (en) 1991-08-08
EP0440219A1 (en) 1991-08-07
JPH04211377A (ja) 1992-08-03

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