HRP20191440T1 - Sastavi koji sadrže bakterijske sojeve - Google Patents
Sastavi koji sadrže bakterijske sojeve Download PDFInfo
- Publication number
- HRP20191440T1 HRP20191440T1 HRP20191440T HRP20191440T1 HR P20191440 T1 HRP20191440 T1 HR P20191440T1 HR P20191440 T HRP20191440 T HR P20191440T HR P20191440 T1 HRP20191440 T1 HR P20191440T1
- Authority
- HR
- Croatia
- Prior art keywords
- composition
- use according
- subject
- bacteria
- blautia hydrogenotrophica
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims 19
- 230000001580 bacterial effect Effects 0.000 title claims 8
- 241000894006 Bacteria Species 0.000 claims 6
- 241000520742 Blautia hydrogenotrophica Species 0.000 claims 6
- 241000736262 Microbiota Species 0.000 claims 4
- 230000000789 acetogenic effect Effects 0.000 claims 3
- 210000000936 intestine Anatomy 0.000 claims 3
- 241000894007 species Species 0.000 claims 3
- 230000002265 prevention Effects 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 1
- 235000013305 food Nutrition 0.000 claims 1
- 208000002551 irritable bowel syndrome Diseases 0.000 claims 1
- 230000000813 microbial effect Effects 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/0208—Specific bacteria not otherwise provided for
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/306—Foods, ingredients or supplements having a functional effect on health having an effect on bone mass, e.g. osteoporosis prevention
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/328—Foods, ingredients or supplements having a functional effect on health having effect on glycaemic control and diabetes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/332—Promoters of weight control and weight loss
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K2035/11—Medicinal preparations comprising living procariotic cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Diabetes (AREA)
- Microbiology (AREA)
- Rheumatology (AREA)
- Nutrition Science (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Obesity (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Child & Adolescent Psychology (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Physical Education & Sports Medicine (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicinal Preparation (AREA)
- Confectionery (AREA)
Claims (13)
1. Sastav koja sadrži bakterijski soj vrsta Blautia hydrogenotrophica, za upotrebu u liječenju ili prevenciji sindroma iritabilnog crijeva, gdje liječenje ili prevencija obuhvaća povećanje raznolikosti mikrobiote kod subjekta.
2. Sastav za upotrebu prema zahtjevu 1, gdje subjekt ima manje od 99 različitih bakterijskih vrsta i/ili manje od 190 različitih bakterijskih vrsta u njegovoj mikrobioti.
3. Sastav za upotrebu prema bilo kojem prethodnom zahtjevu, gdje porast u raznolikosti mikrobiote je za neacetogene bakterije ili za i acetogene i neacetogene bakterije.
4. Sastav za upotrebu prema bilo kojem od prethodnih zahtjeva, gdje :
(a) subjekt je slab stariji subjekt ili
(b) subjekt je novorođenče koje je rođeno carskim rezom.
5. Sastav za upotrebu prema bilo kojem od prethodnih zahtjeva, gdje je raznolikost mikrobiote povećana u crijevu i/ili u distalnom crijevu subjekta.
6. Sastav za upotrebu prema bilo kojem od zahtjeva 1-5, gdje je bakterijski soj bakterija Blautia hydrogenotrophica deponiran pod pristupnim brojem DSM 10507 i također pod pristupnim brojem DSM 14294.
7. Sastav za upotrebu prema kojem od prethodnih zahtjeva, gdje:
(a) Sastav je za oralno davanje; i/ili
(b) Sastav sadrži jedan ili više farmaceutski prihvatljivih ekscipijenata ili nosača; i/ili
(c) bakterijski soj je liofiliziran ; i/ili
(d) bakterijski soj je živ; i/ili
(e) bakterijski soj je u stanju parcijalno ili potpuno kolonizirati crijevo.
8. Sastav za upotrebu prema bilo kojem od prethodnih zahtjeva, koji obuhvaća jedan soj Blautia hydrogenotrophica.
9. Sastav za upotrebu prema bilo kojem od prethodnih zahtjeva, gdje sastav sadrži Blautia hydrogenotrophica i ne sadrži bakteriju bilo kojeg drugog roda ili sadrži takve druge bakterije samo u de minimis količinama.
10. Sastav za upotrebu prema bilo kojem od prethodnih zahtjeva, gdje sastav sadrži Blautia hydrogenotrophica i ne sadrži bakteriju bilo koje druge vrste ili sadrži takve bakterije samo u de minimis količinama.
11. Sastav za upotrebu prema bilo kojem od zahtjeva 1-7, koji sadrži Blautia hydrogenotrophica kao dio mikrobnog konzorcija.
12. Prehrambeni proizvod koji sadrži sastav prema bilo kojem od prethodnih zahtjeva, za upotrebu prema bilo kojem od prethodnih zahtjeva .
13. Sastav cjepiva koji sadrži sastav prema bilo kojem od zahtjeva 1-11, za upotrebu u bilo kojem od zahtjeva 1-11.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1621123.7A GB201621123D0 (en) | 2016-12-12 | 2016-12-12 | Compositions comprising bacterial strains |
PCT/GB2017/053722 WO2018109461A1 (en) | 2016-12-12 | 2017-12-12 | Compositions comprising bacterial strains |
EP17818220.0A EP3359172B1 (en) | 2016-12-12 | 2017-12-12 | Compositions comprising bacterial strains |
Publications (1)
Publication Number | Publication Date |
---|---|
HRP20191440T1 true HRP20191440T1 (hr) | 2019-11-15 |
Family
ID=58222069
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HRP20191440 HRP20191440T1 (hr) | 2016-12-12 | 2019-08-08 | Sastavi koji sadrže bakterijske sojeve |
Country Status (34)
Country | Link |
---|---|
US (5) | US10086021B2 (hr) |
EP (2) | EP3520800A1 (hr) |
JP (2) | JP6517431B2 (hr) |
KR (1) | KR102080040B1 (hr) |
CN (1) | CN109715178A (hr) |
AR (1) | AR110684A1 (hr) |
AU (2) | AU2017374767C1 (hr) |
BR (1) | BR112018077266A2 (hr) |
CA (1) | CA3034202C (hr) |
CO (1) | CO2019000099A2 (hr) |
CY (1) | CY1122162T1 (hr) |
DK (1) | DK3359172T3 (hr) |
EA (1) | EA037687B1 (hr) |
ES (1) | ES2745135T3 (hr) |
GB (1) | GB201621123D0 (hr) |
HK (1) | HK1258574B (hr) |
HR (1) | HRP20191440T1 (hr) |
HU (1) | HUE044677T2 (hr) |
IL (2) | IL263556B (hr) |
LT (1) | LT3359172T (hr) |
MA (2) | MA48647A (hr) |
MD (1) | MD3359172T2 (hr) |
ME (1) | ME03463B (hr) |
MX (2) | MX2018016078A (hr) |
NZ (1) | NZ749872A (hr) |
PL (1) | PL3359172T3 (hr) |
PT (1) | PT3359172T (hr) |
RS (1) | RS59129B1 (hr) |
SG (2) | SG10201913590PA (hr) |
SI (1) | SI3359172T1 (hr) |
TN (1) | TN2019000209A1 (hr) |
TR (1) | TR201911377T4 (hr) |
TW (2) | TW202233215A (hr) |
WO (1) | WO2018109461A1 (hr) |
Families Citing this family (34)
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GB201112091D0 (en) | 2011-07-14 | 2011-08-31 | Gt Biolog Ltd | Bacterial strains isolated from pigs |
GB201117313D0 (en) | 2011-10-07 | 2011-11-16 | Gt Biolog Ltd | Bacterium for use in medicine |
GB201306536D0 (en) | 2013-04-10 | 2013-05-22 | Gt Biolog Ltd | Polypeptide and immune modulation |
MA41020A (fr) | 2014-11-25 | 2017-10-03 | Evelo Biosciences Inc | Compositions probiotiques et prébiotiques, et leurs procédés d'utilisation pour la modulation du microbiome |
JP6393425B2 (ja) * | 2014-12-08 | 2018-09-19 | ジ アサン ファウンデーション | バクテロイデス・アシジファシエンスを有効成分として含む、代謝性疾患の予防又は治療用薬学的組成物 |
JP6427278B2 (ja) | 2014-12-23 | 2018-11-21 | フォーディー ファーマ リサーチ リミテッド4D Pharma Research Limited | pirinポリペプチド及び免疫モジュレーション |
CN108138122B (zh) | 2014-12-23 | 2021-09-21 | 4D制药研究有限公司 | 免疫调控 |
MA41010B1 (fr) | 2015-06-15 | 2020-01-31 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
HUE045413T2 (hu) | 2015-06-15 | 2019-12-30 | 4D Pharma Res Ltd | Baktériumtörzseket tartalmazó készítmények |
SG10201912319SA (en) | 2015-06-15 | 2020-02-27 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
MA41060B1 (fr) | 2015-06-15 | 2019-11-29 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
DK3240554T3 (da) | 2015-06-15 | 2019-10-28 | 4D Pharma Res Ltd | Blautia stercosis og wexlerae til anvendelse til behandling af inflammatoriske og autoimmune sygdomme |
GB201520497D0 (en) | 2015-11-20 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
NZ742787A (en) | 2015-11-20 | 2020-02-28 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
GB201520631D0 (en) | 2015-11-23 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
GB201520638D0 (en) | 2015-11-23 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
ES2731579T3 (es) | 2016-03-04 | 2019-11-18 | 4D Pharma Plc | Composiciones que comprenden cepas de blautia bacteriana para tratar hipersensibilidad visceral |
GB201612191D0 (en) | 2016-07-13 | 2016-08-24 | 4D Pharma Plc | Compositions comprising bacterial strains |
TW201821093A (zh) | 2016-07-13 | 2018-06-16 | 英商4D製藥有限公司 | 包含細菌菌株之組合物 |
GB201621123D0 (en) * | 2016-12-12 | 2017-01-25 | 4D Pharma Plc | Compositions comprising bacterial strains |
RS61872B1 (sr) | 2017-05-22 | 2021-06-30 | 4D Pharma Res Ltd | Kompozicije koje sadrže bakterijske sojeve |
JP6978514B2 (ja) | 2017-05-24 | 2021-12-08 | フォーディー ファーマ リサーチ リミテッド4D Pharma Research Limited | 細菌株を含む組成物 |
HRP20220747T1 (hr) | 2017-06-14 | 2022-10-14 | 4D Pharma Research Limited | Pripravci koji sadrže bakterijske sojeve |
PT3638271T (pt) | 2017-06-14 | 2021-01-05 | 4D Pharma Res Ltd | Composições contendo estirpes bacterianas |
TW202019447A (zh) * | 2018-07-16 | 2020-06-01 | 英商4D製藥研究有限公司 | 包含細菌菌株之組合物 |
JP2022504423A (ja) * | 2018-10-19 | 2022-01-13 | フォーディー ファーマ リサーチ リミテッド | 細菌株を含む組成物 |
EP3947744A1 (en) | 2019-04-03 | 2022-02-09 | 4D Pharma Cork Limited | Methods of diagnosing disease |
CN114514027A (zh) * | 2019-07-19 | 2022-05-17 | 芬奇治疗控股有限责任公司 | 用于治疗胃肠道病症的方法及产品 |
WO2021141828A1 (en) * | 2020-01-10 | 2021-07-15 | Assembly Biosciences, Inc. | Compositions comprising bacterial species and methods related thereto |
CN111304120B (zh) * | 2020-02-24 | 2021-07-23 | 浙江大学 | Blautia sp B2132菌在预防和/或治疗炎症性肠病中的应用 |
MX2022011260A (es) * | 2020-03-10 | 2022-12-15 | Federation Bio Inc | Consorcios microbianos para el tratamiento de enfermedad. |
JP7016182B1 (ja) * | 2020-07-30 | 2022-02-04 | Noster株式会社 | 細菌提供システム |
WO2022251309A2 (en) * | 2021-05-26 | 2022-12-01 | Siolta Therapeutics, Inc. | Pharmaceutical compositions and uses thereof |
WO2023068279A1 (ja) * | 2021-10-18 | 2023-04-27 | 国立研究開発法人医薬基盤・健康・栄養研究所 | ブラウチア(Blautia)属細菌のスクリーニング方法 |
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