HRP20191738T1 - Sastavi koji sadrže bakterijske sojeve - Google Patents
Sastavi koji sadrže bakterijske sojeve Download PDFInfo
- Publication number
- HRP20191738T1 HRP20191738T1 HRP20191738TT HRP20191738T HRP20191738T1 HR P20191738 T1 HRP20191738 T1 HR P20191738T1 HR P20191738T T HRP20191738T T HR P20191738TT HR P20191738 T HRP20191738 T HR P20191738T HR P20191738 T1 HRP20191738 T1 HR P20191738T1
- Authority
- HR
- Croatia
- Prior art keywords
- composition
- cell
- asthma
- bacterial strain
- treatment
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims 16
- 230000001580 bacterial effect Effects 0.000 title claims 6
- 208000006673 asthma Diseases 0.000 claims 5
- 210000004027 cell Anatomy 0.000 claims 5
- 241000872832 Roseburia hominis Species 0.000 claims 4
- 108020004465 16S ribosomal RNA Proteins 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 230000002265 prevention Effects 0.000 claims 3
- 210000000068 Th17 cell Anatomy 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 230000001404 mediated effect Effects 0.000 claims 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims 2
- 206010014950 Eosinophilia Diseases 0.000 claims 1
- 206010029379 Neutrophilia Diseases 0.000 claims 1
- 201000009961 allergic asthma Diseases 0.000 claims 1
- 230000024245 cell differentiation Effects 0.000 claims 1
- 235000013305 food Nutrition 0.000 claims 1
- 230000024949 interleukin-17 production Effects 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Claims (12)
1. Sastav koji obuhvaća bakterijski soj vrste Roseburia hominis, za upotrebu u postupku liječenja ili prevencije astme.
2. Sastav za upotrebu prema zahtjevu 1, pri čemu je sastav za upotrebu u postupku liječenja ili prevencije neutrofilične astme ili alergijske astme.
3. Sastav za upotrebu prema zahtjevu 1 ili 2, pri čemu je sastav za upotrebu u postupku smanjenja neutrofilije ili eozinofilije u liječenju astme.
4. Sastav za upotrebu prema bilo kojem prethodnom zahtjevu, gdje je sastav za upotrebu u postupku smanjenja proizvodnje IL-17 ili smanjenja diferencijacije Th17 stanica u liječenju ili prevenciji astme koja je posredovana s IL-17 ili putem Th17; i/ili gdje je sastav za upotrebu kod pacijenta s povećanim razinama IL-17 ili Th17 stanicama.
5. Sastav za upotrebu prema bilo kojem od zahtjeva 1-4, pri čemu bakterijski soj ima 16s rRNK sekvencu koja je najmanje 98%, 99%, 99.5% ili 99.9% identična sa SEQ ID NO:1, 2 ili 3; poželjno gdje bakterijski soj ima 16s rRNK sekvencu koja je najmanje 98%, 99%, 99.5% ili 99.9% identična sa SEQ ID NO:3, ili gdje bakterijski soj ima 16s rRNK sekvencu koja je predstavljena sa SEQ ID NO:3.
6. Sastav za upotrebu prema bilo kojem prethodnom zahtjevu, pri čemu (i) sastav je za oralnu primjenu; i/ili (ii) sastav obuhvaća jednu ili više farmaceutski prihvatljivih pomoćnih tvari ili nosača; i/ili (iii) bakterijski soj je liofiliziran.
7. Prehrambeni proizvod ili sastav cjepiva koji obuhvaća sastav prema bilo kojem prethodnom zahtjevu, za upotrebu prema bilo kojem prethodnom zahtjevu.
8. Stanica Roseburia hominis soja koja je deponirana pod pristupnim brojem NCIMB 42383.
9. Sastav koja obuhvaća stanicu prema zahtjevu 8, koja opcionalno obuhvaća farmaceutski prihvatljivi nosač ili pomoćnu tvar.
10. Biološki čista kultura Roseburia hominis soja koja je deponirana pod pristupnim brojem NCIMB 42383.
11. Stanica Roseburia hominis soja koja je deponirana pod pristupnim brojem NCIMB 42383, za upotrebu u terapiji.
12. Stanica prema zahtjevu 11, pri čemu je stanica za upotrebu u postupku koji je definiran u bilo kojem od zahtjeva 1-4.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1510468.0A GB201510468D0 (en) | 2015-06-15 | 2015-06-15 | Compositions comprising bacterial strains |
GB201606807 | 2016-04-19 | ||
PCT/GB2016/051774 WO2016203221A1 (en) | 2015-06-15 | 2016-06-15 | Compositions comprising bacterial strains |
EP16731642.1A EP3307288B1 (en) | 2015-06-15 | 2016-06-15 | Compositions comprising bacterial strains |
Publications (1)
Publication Number | Publication Date |
---|---|
HRP20191738T1 true HRP20191738T1 (hr) | 2019-12-27 |
Family
ID=56194513
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HRP20191738TT HRP20191738T1 (hr) | 2015-06-15 | 2019-09-25 | Sastavi koji sadrže bakterijske sojeve |
Country Status (30)
Country | Link |
---|---|
US (3) | US10500237B2 (hr) |
EP (2) | EP3307288B1 (hr) |
JP (3) | JP6426264B2 (hr) |
KR (1) | KR20180012849A (hr) |
CN (2) | CN114984057A (hr) |
AU (2) | AU2016278070B2 (hr) |
CA (1) | CA2988693A1 (hr) |
CL (1) | CL2017003193A1 (hr) |
CO (1) | CO2017013287A2 (hr) |
CY (1) | CY1122184T1 (hr) |
DK (1) | DK3307288T3 (hr) |
EA (1) | EA201890050A1 (hr) |
ES (1) | ES2748812T3 (hr) |
HK (1) | HK1246675A1 (hr) |
HR (1) | HRP20191738T1 (hr) |
HU (1) | HUE045413T2 (hr) |
IL (2) | IL256009B (hr) |
LT (1) | LT3307288T (hr) |
MA (1) | MA42471B1 (hr) |
MD (1) | MD3307288T2 (hr) |
ME (1) | ME03563B (hr) |
MX (1) | MX2017016529A (hr) |
PE (1) | PE20180267A1 (hr) |
PL (1) | PL3307288T3 (hr) |
PT (1) | PT3307288T (hr) |
RS (1) | RS59308B1 (hr) |
SG (1) | SG10201912326QA (hr) |
SI (1) | SI3307288T1 (hr) |
TW (2) | TW202222339A (hr) |
WO (1) | WO2016203221A1 (hr) |
Families Citing this family (53)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB201112091D0 (en) | 2011-07-14 | 2011-08-31 | Gt Biolog Ltd | Bacterial strains isolated from pigs |
GB201117313D0 (en) | 2011-10-07 | 2011-11-16 | Gt Biolog Ltd | Bacterium for use in medicine |
GB201306536D0 (en) | 2013-04-10 | 2013-05-22 | Gt Biolog Ltd | Polypeptide and immune modulation |
BR112017013274A2 (pt) | 2014-12-23 | 2018-02-06 | 4D Pharma Research Limited | polipeptídeo e imunomodulação |
SG11201704811YA (en) | 2014-12-23 | 2017-07-28 | 4D Pharma Res Ltd | Immune modulation |
CN115364122A (zh) | 2015-06-15 | 2022-11-22 | 4D制药研究有限公司 | 包含细菌菌株的组合物 |
NZ737752A (en) | 2015-06-15 | 2022-02-25 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
SI3307288T1 (sl) | 2015-06-15 | 2019-11-29 | 4D Pharma Res Ltd | Spojine, ki vsebujejo bakterijske seve |
MA41060B1 (fr) | 2015-06-15 | 2019-11-29 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
MA41010B1 (fr) | 2015-06-15 | 2020-01-31 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
CN112569262A (zh) | 2015-11-20 | 2021-03-30 | 4D制药研究有限公司 | 包含细菌菌株的组合物 |
GB201520497D0 (en) | 2015-11-20 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
GB201520638D0 (en) | 2015-11-23 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
GB201520631D0 (en) | 2015-11-23 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
CN108883139B (zh) | 2016-03-04 | 2022-04-26 | 4D制药有限公司 | 包含细菌菌株的组合物 |
GB201612191D0 (en) | 2016-07-13 | 2016-08-24 | 4D Pharma Plc | Compositions comprising bacterial strains |
US9999641B2 (en) | 2016-06-14 | 2018-06-19 | Vedanta Biosciences, Inc. | Treatment of clostridium difficile infection |
TW201821093A (zh) | 2016-07-13 | 2018-06-16 | 英商4D製藥有限公司 | 包含細菌菌株之組合物 |
GB201621123D0 (en) | 2016-12-12 | 2017-01-25 | 4D Pharma Plc | Compositions comprising bacterial strains |
EP3369423A1 (en) * | 2017-03-01 | 2018-09-05 | Reminisciences | Synbiotic composition and its use for preventing and/or treating neurodegenerative disorders |
WO2018187272A1 (en) | 2017-04-03 | 2018-10-11 | Gusto Global, Llc | Rational design of microbial-based biotherapeutics |
US11666627B2 (en) | 2017-04-07 | 2023-06-06 | Second Genome, Inc. | Proteins for the treatment of epithelial barrier function disorders |
AU2018248324B2 (en) * | 2017-04-07 | 2023-02-09 | Genevive, Inc. | Proteins for the treatment of epithelial barrier function disorders |
MA48939B1 (fr) | 2017-05-22 | 2021-06-30 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
EP3630942B1 (en) | 2017-05-24 | 2022-11-30 | 4D Pharma Research Limited | Compositions comprising bacterial strain |
RS61210B1 (sr) * | 2017-06-14 | 2021-01-29 | 4D Pharma Res Ltd | Kompozicije koje sadrže bakterijske sojeve |
JP6837581B2 (ja) | 2017-06-14 | 2021-03-03 | フォーディー ファーマ リサーチ リミテッド4D Pharma Research Limited | Megasphaera属の細菌株を含む組成物及びその使用 |
JP2020529478A (ja) * | 2017-08-04 | 2020-10-08 | セカンド ゲノム インコーポレイテッド | バイオ治療薬としてのロゼブリア・ホミニス(roseburia hominis)、ユーバクテリウム・エリゲンス(eubacterium eligens)、およびこれらの組み合わせ |
WO2019115759A1 (en) * | 2017-12-14 | 2019-06-20 | Københavns Universitet | Bacterial compositions and the use thereof for the treatment or prevention of asthma or other wheezing disorders or allergy in a child |
US11505583B2 (en) | 2018-04-06 | 2022-11-22 | Second Genome, Inc. | Proteins for the treatment of epithelial barrier function disorders |
WO2019238969A1 (en) * | 2018-06-14 | 2019-12-19 | 4D Pharma Research Ltd | Compositions comprising bacterial strains |
CN109136396A (zh) * | 2018-09-19 | 2019-01-04 | 华南农业大学 | 一种魏氏梭菌病的特异性检测引物和检测试剂盒 |
CN110204602B (zh) * | 2019-06-10 | 2021-11-23 | 山东农业大学 | 一种抗真菌的抗菌肽及其应用 |
WO2021137305A1 (ko) * | 2019-12-30 | 2021-07-08 | 경상대학교병원 | 박테리아 감염증 예방 또는 치료용 약학 조성물 |
GB202007452D0 (en) | 2020-05-19 | 2020-07-01 | Microbiotica Ltd | Threrapeutic bacterial composition |
CN112342312B (zh) * | 2020-12-09 | 2022-08-16 | 华中农业大学 | 一种甘蓝型油菜hau CMS育性恢复基因的分子标记及应用 |
CN113106082B (zh) * | 2021-05-27 | 2022-11-04 | 云南师范大学 | 动物粪便宏基因组来源的丙氨酸消旋酶及其制备和应用 |
KR102337995B1 (ko) * | 2021-11-10 | 2021-12-14 | 주식회사 바이오뱅크힐링 | 아가토바쿨룸 부티리시프로두켄스 균주, 및 그의 유래의 소포체 및 그의 항염증 및 항균 용도 |
WO2023075458A1 (ko) * | 2021-10-27 | 2023-05-04 | 주식회사 바이오뱅크힐링 | 신규 균주, 및 그의 유래의 소포체 및 그의 항염증 및 항균 용도 |
KR102337998B1 (ko) | 2021-11-03 | 2021-12-14 | 주식회사 바이오뱅크힐링 | 로제부리아 파에시스 균주, 및 그의 유래의 소포체 및 그의 항염증 및 항균 용도 |
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KR102438867B1 (ko) | 2022-03-11 | 2022-09-02 | 주식회사 바이오뱅크힐링 | 코프로코커스 캐터스 균주, 및 그의 유래의 소포체 및 그의 항염증 및 항균 용도 |
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