CO2018009538A2 - Uso de cepas bacterianas pertenecientes a la especie lactobacillus kefiri en pediatría para generar y/o mantener un estado de homeostasis - Google Patents

Uso de cepas bacterianas pertenecientes a la especie lactobacillus kefiri en pediatría para generar y/o mantener un estado de homeostasis

Info

Publication number
CO2018009538A2
CO2018009538A2 CONC2018/0009538A CO2018009538A CO2018009538A2 CO 2018009538 A2 CO2018009538 A2 CO 2018009538A2 CO 2018009538 A CO2018009538 A CO 2018009538A CO 2018009538 A2 CO2018009538 A2 CO 2018009538A2
Authority
CO
Colombia
Prior art keywords
bacterial strains
lactobacillus kefiri
pediatrics
present
composition
Prior art date
Application number
CONC2018/0009538A
Other languages
English (en)
Inventor
Giovanni Mogna
Original Assignee
Probiotical Spa
Hulka S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ITUB2016A000708A external-priority patent/ITUB20160708A1/it
Priority claimed from ITUA2016A003324A external-priority patent/ITUA20163324A1/it
Application filed by Probiotical Spa, Hulka S R L filed Critical Probiotical Spa
Publication of CO2018009538A2 publication Critical patent/CO2018009538A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00—Lactic or propionic acid bacteria
    • A23V2400/11—Lactobacillus
    • A23V2400/155—Kefiri
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11—Medicinal preparations comprising living procariotic cells
    • A61K2035/115—Probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/225—Lactobacillus

Abstract

La presente invención se refiere al uso de cepas bacterianas pertenecientes a la especie Lactobacillus kefiri en pediatría para generar y/o mantener el estado de homeostasis. La presente invención se refiere además a cepas bacterianas que pertenecen a la especie Lactobacillus kefiri que tiene una alta capacidad para adherirse al epitelio intestinal; en particular, la presente invención se refiere a las cepas bacterianas Lactobacillus kefiri LKF01 DSM 32079 LKEF y Lactobacillus kefiri LKF02 DSM 32080 para uso en pediatría. Finalmente, la presente invención se refiere a una composición alimenticia, o una composición para un suplemento, o una composición para un dispositivo médico, o una composición farmacéutica (en resumen, todas juntas las composiciones de la presente invención) que comprende excipientes y/o sustancias de una formulación de grado alimentario o farmacéutico, y una mezcla que comprende o, alternativamente, consiste en una cepa bacteriana seleccionada del grupo que consiste en las cepas bacterianas que pertenecen a la especie Lactobacillus kefiri, siendo dicha composición para uso en pediatría para generar y/o mantener el estado de homeostasis y para su uso en el tratamiento preventivo y/o curativo de enfermedades intestinales inflamatorias, como el síndrome del intestino irritable (IBS), enfermedad inflamatoria intestinal (IBD), enfermedad de Crohn y colitis ulcerosa (UC), en sujetos adultos, también en una etapa crónica.
CONC2018/0009538A 2016-02-12 2018-09-12 Uso de cepas bacterianas pertenecientes a la especie lactobacillus kefiri en pediatría para generar y/o mantener un estado de homeostasis CO2018009538A2 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITUB2016A000708A ITUB20160708A1 (it) 2016-02-12 2016-02-12 Uso di ceppi di batteri appartenenti alla specie Lactobacillus kefiri in pediatria per generare e/o mantenere lo stato di omeostasi.
ITUA2016A003324A ITUA20163324A1 (it) 2016-05-10 2016-05-10 Uso di ceppi di batteri appartenenti alla specie Lactobacillus kefiri in pediatria per generare e/o mantenere lo stato di omeostasi.
PCT/IB2017/050713 WO2017137920A2 (en) 2016-02-12 2017-02-09 Use of bacterial strains belonging to the species lactobacillus kefiri in paediatrics to generate and/or mantai n a state of homeostasis

Publications (1)

Publication Number Publication Date
CO2018009538A2 true CO2018009538A2 (es) 2018-12-14

Family

ID=58401927

Family Applications (1)

Application Number Title Priority Date Filing Date
CONC2018/0009538A CO2018009538A2 (es) 2016-02-12 2018-09-12 Uso de cepas bacterianas pertenecientes a la especie lactobacillus kefiri en pediatría para generar y/o mantener un estado de homeostasis

Country Status (10)

Country Link
US (1) US20190038682A1 (es)
EP (1) EP3414317A2 (es)
CN (1) CN108779433A (es)
AU (1) AU2017217350A1 (es)
BR (1) BR112018016458A2 (es)
CA (1) CA3013280A1 (es)
CL (1) CL2018002148A1 (es)
CO (1) CO2018009538A2 (es)
PE (1) PE20190122A1 (es)
WO (1) WO2017137920A2 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT201800005359A1 (it) * 2018-05-14 2019-11-14 Ceppo probiotico Lactobacillus kefiri SGL 13 e suo uso per la prevenzione e il trattamento delle infiammazioni intestinali e nella prevenzione delle neoplasie intestinali
FR3084255B1 (fr) * 2018-07-26 2020-07-03 Institut National De La Recherche Agronomique (Inra) Souche de streptococcus thermophilus cnrz160 pour le traitement et la prevention de l'inflammation intestinale et des desordres associes, chez un individu
CN110184214B (zh) * 2019-05-21 2022-07-01 黑龙江大学 一种开菲尔乳杆菌及其菌制剂
CN110144311B (zh) * 2019-05-21 2022-07-01 黑龙江大学 一种开菲尔乳杆菌及其菌制剂
IT201900020805A1 (it) * 2019-11-11 2021-05-11 Probiotical Spa Batteri granulari gastroprotetti con matrice di rivestimento in forma cristallina, procedimento per la loro preparazione e loro composizioni
CN112501049B (zh) * 2020-10-28 2022-04-19 石河子大学 产转糖基活性β-半乳糖苷酶的开菲尔乳杆菌及制备的β-半乳糖苷酶生产低聚半乳糖的方法
CN114767716B (zh) * 2022-04-24 2024-03-26 华南农业大学 一种开菲尔乳清和茶多酚组合物及其制备方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101399712B1 (ko) * 2008-06-10 2014-06-20 가부시키가이샤 피스 신규 유발효물 및 그의 이용
JP2013531506A (ja) * 2010-06-28 2013-08-08 プロバイオティカル・ソシエタ・ペル・アチオニ 疝痛に罹患した幼児から単離したガス産生大腸菌群を阻害するｌａｃｔｏｂａｃｉｌｌｉの使用
TWI450722B (zh) * 2011-01-31 2014-09-01 Univ Nat Taiwan 經分離之乳酸桿菌及其用途
CN104560793A (zh) * 2014-12-17 2015-04-29 石家庄君乐宝乳业有限公司 开菲尔乳杆菌kl22、其筛选方法及应用

Also Published As

Publication number Publication date
BR112018016458A2 (pt) 2018-12-26
CN108779433A (zh) 2018-11-09
CL2018002148A1 (es) 2019-01-04
PE20190122A1 (es) 2019-01-17
CA3013280A1 (en) 2017-08-17
EP3414317A2 (en) 2018-12-19
WO2017137920A3 (en) 2017-10-26
AU2017217350A1 (en) 2018-08-09
US20190038682A1 (en) 2019-02-07
WO2017137920A2 (en) 2017-08-17

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