BR112018016458A2 - uso de cepas bacterianas pertencentes à espécie lactobacillus kefiri em pediatria para gerar e/ou manter um estado de homeostase - Google Patents

uso de cepas bacterianas pertencentes à espécie lactobacillus kefiri em pediatria para gerar e/ou manter um estado de homeostase

Info

Publication number
BR112018016458A2
BR112018016458A2 BR112018016458A BR112018016458A BR112018016458A2 BR 112018016458 A2 BR112018016458 A2 BR 112018016458A2 BR 112018016458 A BR112018016458 A BR 112018016458A BR 112018016458 A BR112018016458 A BR 112018016458A BR 112018016458 A2 BR112018016458 A2 BR 112018016458A2
Authority
BR
Brazil
Prior art keywords
bacterial strains
lactobacillus kefiri
pediatrics
species
present
Prior art date
Application number
BR112018016458A
Other languages
English (en)
Inventor
Mogna Giovanni
Original Assignee
Hulka S R L
Probiotical Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ITUB2016A000708A external-priority patent/ITUB20160708A1/it
Priority claimed from ITUA2016A003324A external-priority patent/ITUA20163324A1/it
Application filed by Hulka S R L, Probiotical Spa filed Critical Hulka S R L
Publication of BR112018016458A2 publication Critical patent/BR112018016458A2/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00—Lactic or propionic acid bacteria
    • A23V2400/11—Lactobacillus
    • A23V2400/155—Kefiri
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11—Medicinal preparations comprising living procariotic cells
    • A61K2035/115—Probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/225—Lactobacillus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

a presente invenção refere-se ao uso de cepas bacterianas pertencentes à espécie lactobacillus kefiri em pediatria para gerar e/ou manter o estado de homeostase. a presente invenção refere-se ainda às cepas bacterianas pertencentes à espécie lactobacillus kefiri com uma elevada capacidade para aderir ao epitélio intestinal; em particular, a presente invenção refere-se às cepas bacterianas lactobacillus kefiri lkf01 dsm 32079 lkef e lactobacillus kefiri lkf02 dsm 32080 para utilização em pediatria. finalmente, a presente invenção refere-se a uma composição alimentar, ou uma composição para um suplemento, ou uma composição para um dispositivo médico, ou uma composição farmacêutica (brevemente todas as composições da presente invenção) compreendendo excipientes e/ou substâncias de uma formulação alimentar ou de grau farmacêutico e uma mistura compreendendo ou, alternativamente, consistindo numa cepa bacteriana selecionada do grupo consistindo nas cepas bacterianas pertencentes espécie lactobacillus kefiri, sendo a referida composição para utilização em pediatria para gerar e/ou manter o estado de homeostase e para uso no tratamento preventivo e/ou curativo de doenças intestinais inflamatórias, como síndrome do intestino irritável (ibs), doença inflamatória intestinal (ibd), doença de crohn e colite ulcerativa (uc), em adultos, também em um estágio crônico.
BR112018016458A 2016-02-12 2017-02-09 uso de cepas bacterianas pertencentes à espécie lactobacillus kefiri em pediatria para gerar e/ou manter um estado de homeostase BR112018016458A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITUB2016A000708A ITUB20160708A1 (it) 2016-02-12 2016-02-12 Uso di ceppi di batteri appartenenti alla specie Lactobacillus kefiri in pediatria per generare e/o mantenere lo stato di omeostasi.
ITUA2016A003324A ITUA20163324A1 (it) 2016-05-10 2016-05-10 Uso di ceppi di batteri appartenenti alla specie Lactobacillus kefiri in pediatria per generare e/o mantenere lo stato di omeostasi.
PCT/IB2017/050713 WO2017137920A2 (en) 2016-02-12 2017-02-09 Use of bacterial strains belonging to the species lactobacillus kefiri in paediatrics to generate and/or mantai n a state of homeostasis

Publications (1)

Publication Number Publication Date
BR112018016458A2 true BR112018016458A2 (pt) 2018-12-26

Family

ID=58401927

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112018016458A BR112018016458A2 (pt) 2016-02-12 2017-02-09 uso de cepas bacterianas pertencentes à espécie lactobacillus kefiri em pediatria para gerar e/ou manter um estado de homeostase

Country Status (10)

Country Link
US (1) US20190038682A1 (pt)
EP (1) EP3414317A2 (pt)
CN (1) CN108779433A (pt)
AU (1) AU2017217350A1 (pt)
BR (1) BR112018016458A2 (pt)
CA (1) CA3013280A1 (pt)
CL (1) CL2018002148A1 (pt)
CO (1) CO2018009538A2 (pt)
PE (1) PE20190122A1 (pt)
WO (1) WO2017137920A2 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT201800005359A1 (it) * 2018-05-14 2019-11-14 Ceppo probiotico Lactobacillus kefiri SGL 13 e suo uso per la prevenzione e il trattamento delle infiammazioni intestinali e nella prevenzione delle neoplasie intestinali
FR3084255B1 (fr) * 2018-07-26 2020-07-03 Institut National De La Recherche Agronomique (Inra) Souche de streptococcus thermophilus cnrz160 pour le traitement et la prevention de l'inflammation intestinale et des desordres associes, chez un individu
CN110184214B (zh) * 2019-05-21 2022-07-01 黑龙江大学 一种开菲尔乳杆菌及其菌制剂
CN110144311B (zh) * 2019-05-21 2022-07-01 黑龙江大学 一种开菲尔乳杆菌及其菌制剂
IT201900020805A1 (it) * 2019-11-11 2021-05-11 Probiotical Spa Batteri granulari gastroprotetti con matrice di rivestimento in forma cristallina, procedimento per la loro preparazione e loro composizioni
CN112501049B (zh) * 2020-10-28 2022-04-19 石河子大学 产转糖基活性β-半乳糖苷酶的开菲尔乳杆菌及制备的β-半乳糖苷酶生产低聚半乳糖的方法
CN114767716B (zh) * 2022-04-24 2024-03-26 华南农业大学 一种开菲尔乳清和茶多酚组合物及其制备方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102056489B (zh) * 2008-06-10 2012-08-01 株式会社妃丝 新型发酵乳及其应用
JP2013531506A (ja) * 2010-06-28 2013-08-08 プロバイオティカル・ソシエタ・ペル・アチオニ 疝痛に罹患した幼児から単離したガス産生大腸菌群を阻害するｌａｃｔｏｂａｃｉｌｌｉの使用
TWI450722B (zh) * 2011-01-31 2014-09-01 Univ Nat Taiwan 經分離之乳酸桿菌及其用途
CN104560793A (zh) * 2014-12-17 2015-04-29 石家庄君乐宝乳业有限公司 开菲尔乳杆菌kl22、其筛选方法及应用

Also Published As

Publication number Publication date
US20190038682A1 (en) 2019-02-07
WO2017137920A3 (en) 2017-10-26
CO2018009538A2 (es) 2018-12-14
PE20190122A1 (es) 2019-01-17
CA3013280A1 (en) 2017-08-17
CN108779433A (zh) 2018-11-09
WO2017137920A2 (en) 2017-08-17
EP3414317A2 (en) 2018-12-19
CL2018002148A1 (es) 2019-01-04
AU2017217350A1 (en) 2018-08-09

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B350 Update of information on the portal [chapter 15.35 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

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B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2656 DE 30-11-2021 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.