WO2019066577A3 - 짧은 사슬 지방산 생성 장내 세균 군집의 변화를 이용한 알코올성 간 질환의 진단 및 치료용 조성물 - Google Patents
짧은 사슬 지방산 생성 장내 세균 군집의 변화를 이용한 알코올성 간 질환의 진단 및 치료용 조성물 Download PDFInfo
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- WO2019066577A3 WO2019066577A3 PCT/KR2018/011564 KR2018011564W WO2019066577A3 WO 2019066577 A3 WO2019066577 A3 WO 2019066577A3 KR 2018011564 W KR2018011564 W KR 2018011564W WO 2019066577 A3 WO2019066577 A3 WO 2019066577A3
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- WIPO (PCT)
- Prior art keywords
- composition
- diagnosis
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Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 230000001580 bacterial effect Effects 0.000 title abstract 3
- 208000022309 Alcoholic Liver disease Diseases 0.000 title 1
- 238000003745 diagnosis Methods 0.000 title 1
- 150000004666 short chain fatty acids Chemical class 0.000 title 1
- 208000007082 Alcoholic Fatty Liver Diseases 0.000 abstract 4
- 206010016262 Fatty liver alcoholic Diseases 0.000 abstract 4
- 208000026594 alcoholic fatty liver disease Diseases 0.000 abstract 4
- 208000010706 fatty liver disease Diseases 0.000 abstract 4
- 239000000090 biomarker Substances 0.000 abstract 1
- 235000013305 food Nutrition 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000006041 probiotic Substances 0.000 abstract 1
- 235000018291 probiotics Nutrition 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/0208—Specific bacteria not otherwise provided for
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
- C12Q1/06—Quantitative determination
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/20—Natural extracts
- A23V2250/206—Bacterial extracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K2035/11—Medicinal preparations comprising living procariotic cells
- A61K2035/115—Probiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/542—Mucosal route oral/gastrointestinal
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Polymers & Plastics (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Toxicology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16/648,358 US11510948B2 (en) | 2017-09-28 | 2018-09-28 | Composition for diagnosis and treatment of alcoholic liver disease, using change in short-chain fatty acid producing gut bacterial community |
AU2018341734A AU2018341734B2 (en) | 2017-09-28 | 2018-09-28 | Composition for diagnosis and treatment of alcoholic liver disease, using change in short-chain fatty acid producing gut bacterial community |
EP18860264.3A EP3690026A4 (en) | 2017-09-28 | 2018-09-28 | COMPOSITION FOR THE DIAGNOSIS AND TREATMENT OF ALCOHOLIC LIVER DISEASE USING A MODIFICATION IN THE SHORT CHAIN FATTY ACID-PRODUCING INTESTINAL COMMUNITY |
CA3076884A CA3076884A1 (en) | 2017-09-28 | 2018-09-28 | Composition for diagnosis and treatment of alcoholic liver disease, using change in short-chain fatty acid producing gut bacterial community |
JP2020518722A JP7033655B2 (ja) | 2017-09-28 | 2018-09-28 | 短鎖脂肪酸生成腸内細菌群集の変化を用いたアルコール性肝疾患の診断および治療用組成物 |
CN201880076591.7A CN111527195B (zh) | 2017-09-28 | 2018-09-28 | 用产生短链脂肪酸的肠道细菌群落的改变诊断和治疗酒精性肝病的组合物 |
US18/050,091 US11903980B2 (en) | 2017-09-28 | 2022-10-27 | Composition for diagnosis and treatment of alcoholic liver disease, using change in short-chain fatty acid producing gut bacterial community |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR20170126557 | 2017-09-28 | ||
KR10-2017-0126557 | 2017-09-28 | ||
KR1020180115823A KR102212606B1 (ko) | 2017-09-28 | 2018-09-28 | 짧은 사슬 지방산 생성 장내 세균 군집의 변화를 이용한 알코올성 간 질환의 진단 및 치료용 조성물 |
KR10-2018-0115823 | 2018-09-28 |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US16/648,358 A-371-Of-International US11510948B2 (en) | 2017-09-28 | 2018-09-28 | Composition for diagnosis and treatment of alcoholic liver disease, using change in short-chain fatty acid producing gut bacterial community |
US18/050,091 Continuation US11903980B2 (en) | 2017-09-28 | 2022-10-27 | Composition for diagnosis and treatment of alcoholic liver disease, using change in short-chain fatty acid producing gut bacterial community |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2019066577A2 WO2019066577A2 (ko) | 2019-04-04 |
WO2019066577A3 true WO2019066577A3 (ko) | 2019-07-04 |
Family
ID=66104379
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/KR2018/011564 WO2019066577A2 (ko) | 2017-09-28 | 2018-09-28 | 짧은 사슬 지방산 생성 장내 세균 군집의 변화를 이용한 알코올성 간 질환의 진단 및 치료용 조성물 |
Country Status (8)
Country | Link |
---|---|
US (2) | US11510948B2 (ko) |
EP (1) | EP3690026A4 (ko) |
JP (1) | JP7033655B2 (ko) |
KR (1) | KR102212606B1 (ko) |
CN (1) | CN111527195B (ko) |
AU (1) | AU2018341734B2 (ko) |
CA (1) | CA3076884A1 (ko) |
WO (1) | WO2019066577A2 (ko) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109259146B (zh) * | 2018-08-27 | 2022-05-20 | 南昌大学 | 鼠李糖乳杆菌在制备具有抑制脂肪肝病变功效的组合物中的应用 |
US20220211780A1 (en) * | 2019-05-21 | 2022-07-07 | Pendulum Therapeutics, Inc. | Methods And Compositions For Treating Liver Disorders |
KR102363094B1 (ko) | 2020-06-19 | 2022-02-16 | 한국식품연구원 | 장내 미생물을 이용한 간질환 위험도 예측 또는 진단용 조성물, 그를 이용한 진단키트, 정보제공방법 및 간질환 예방 또는 치료제 스크리닝 방법 |
CN111733137A (zh) * | 2020-07-13 | 2020-10-02 | 江南大学 | 一种筛选可预防和/或治疗酒精性肝损伤的药物的方法 |
KR20220041406A (ko) | 2020-09-25 | 2022-04-01 | 한국식품연구원 | 장내 미생물을 이용한 간질환 개선, 예방 또는 치료용 조성물 및 그를 이용한 간질환의 치료방법 |
CN113181151A (zh) * | 2020-12-29 | 2021-07-30 | 山东善维免疫科技有限公司 | 短链脂肪酸在预防或/和治疗肝损伤中的应用 |
KR102646205B1 (ko) | 2021-02-15 | 2024-03-12 | 국립안동대학교 산학협력단 | 엘라그산을 유효성분으로 포함하는 장내 미생물 개선용 조성물 |
WO2023126384A1 (en) * | 2021-12-27 | 2023-07-06 | Mrm Health N.V. | Microbial communities |
WO2023140603A1 (ko) * | 2022-01-20 | 2023-07-27 | 한국과학기술연구원 | 로세부리아 속 또는 비피도박테리움 속 유래 세포외소포체를 포함하는, 비알코올성 지방간 질환의 예방, 개선, 또는 치료용 조성물 |
CN114621936B (zh) * | 2022-03-02 | 2023-10-24 | 中南大学湘雅二医院 | 蛋白组合物及其用途 |
CN114796285B (zh) * | 2022-04-29 | 2023-06-23 | 大连工业大学 | 嗜黏蛋白阿克曼氏菌在缓解高尿酸血症中的应用 |
CN114854884A (zh) * | 2022-05-27 | 2022-08-05 | 山东农业大学 | 用属水平的粪便微生物预警或无创诊断脂肪肝奶牛的方法 |
Citations (1)
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US20150071957A1 (en) * | 2013-04-10 | 2015-03-12 | Gt Biologics Ltd | Polypeptide and immune modulation |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101158472B1 (ko) * | 2009-11-05 | 2012-06-20 | 주식회사 베네비오 | 알코올에 유발된 간질환의 예방 또는 치료용 조성물 |
KR101303541B1 (ko) * | 2011-06-15 | 2013-09-03 | 세명대학교 산학협력단 | 알코올성 간손상 내지 알코올성 지방간 예방 및 숙취해소 효과를 갖는 조성물 |
EP2744890A4 (en) * | 2011-09-14 | 2015-07-08 | Univ Kingston | METHOD FOR TREATING DISORDERS OF THE GASTROINTESTINAL DEVICE |
GB201117313D0 (en) * | 2011-10-07 | 2011-11-16 | Gt Biolog Ltd | Bacterium for use in medicine |
EP2969012A4 (en) | 2013-03-12 | 2016-09-14 | Univ Yale | COMPOSITIONS AND METHODS FOR IDENTIFYING MICROBES RELATED TO SECRETORY ANTIBODIES |
CN104413334A (zh) * | 2013-08-30 | 2015-03-18 | 深圳华大基因科技有限公司 | 可食用组合物及其制备方法和用途 |
WO2016172658A2 (en) | 2015-04-23 | 2016-10-27 | Kaleido Biosciences, Inc. | Microbiome regulators and related uses thereof |
DK3626081T3 (da) | 2015-09-10 | 2022-02-28 | Univ Catholique Louvain | Pasteuriseret akkermansia til fremme af vægttab |
KR20170032815A (ko) | 2015-09-15 | 2017-03-23 | 경희대학교 산학협력단 | 신규 유산균 및 퇴행성 뇌질환 또는 인지기능의 예방, 개선 또는 치료용 조성물 |
TWI589297B (zh) * | 2016-04-25 | 2017-07-01 | Use of melon leaf extract for the treatment and / or prevention of alcoholic fatty liver or its complications | |
JP2020530840A (ja) * | 2017-08-14 | 2020-10-29 | セレス セラピューティクス インコーポレイテッド | 胆汁うっ滞性疾患を治療するための組成物及び方法 |
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2018
- 2018-09-28 AU AU2018341734A patent/AU2018341734B2/en active Active
- 2018-09-28 KR KR1020180115823A patent/KR102212606B1/ko active IP Right Grant
- 2018-09-28 WO PCT/KR2018/011564 patent/WO2019066577A2/ko unknown
- 2018-09-28 JP JP2020518722A patent/JP7033655B2/ja active Active
- 2018-09-28 EP EP18860264.3A patent/EP3690026A4/en active Pending
- 2018-09-28 CN CN201880076591.7A patent/CN111527195B/zh active Active
- 2018-09-28 US US16/648,358 patent/US11510948B2/en active Active
- 2018-09-28 CA CA3076884A patent/CA3076884A1/en active Pending
-
2022
- 2022-10-27 US US18/050,091 patent/US11903980B2/en active Active
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20150071957A1 (en) * | 2013-04-10 | 2015-03-12 | Gt Biologics Ltd | Polypeptide and immune modulation |
Non-Patent Citations (4)
Title |
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CLARK, ALLISON: "The crosstalk between the Gut Microbiota and Mitochondria during exercise", FRONTIERS IN PHYSIOLOGY, vol. 8, no. 319, 19 May 2017 (2017-05-19), pages 1 - 17, XP055623507 * |
LAU, E.: "Gut microbiota: association with NAFLD and metabolic disturbances", BIOMED RESEARCH INTERNATIONAL, vol. 2015, 19 May 2015 (2015-05-19), pages 1 - 9, XP055623510 * |
TAMANAI-SHACOORI, ZOHREH ET AL.: "Roseburia spp.: a marker of health?", FUTURE MICROBIOLOGY, vol. 12, no. 2, 31 January 2017 (2017-01-31), pages 157 - 170, XP055499590 * |
USAMI, MAKOTO: "Gut microbiota and host metabolism in liver cirrhosis", WORLD JOURNAL OF GASTROENTEROLOGY, vol. 21, no. 41, 7 November 2015 (2015-11-07), pages 11597 - 11608, XP055623516 * |
Also Published As
Publication number | Publication date |
---|---|
JP7033655B2 (ja) | 2022-03-10 |
AU2018341734B2 (en) | 2022-02-03 |
EP3690026A2 (en) | 2020-08-05 |
US11510948B2 (en) | 2022-11-29 |
WO2019066577A2 (ko) | 2019-04-04 |
EP3690026A4 (en) | 2021-06-23 |
US20230190829A1 (en) | 2023-06-22 |
AU2018341734A1 (en) | 2020-04-16 |
US11903980B2 (en) | 2024-02-20 |
CA3076884A1 (en) | 2019-04-04 |
CN111527195B (zh) | 2023-11-03 |
KR20190037170A (ko) | 2019-04-05 |
JP2020534858A (ja) | 2020-12-03 |
KR102212606B1 (ko) | 2021-02-05 |
US20210052674A1 (en) | 2021-02-25 |
CN111527195A (zh) | 2020-08-11 |
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