HRP20120136T1 - Imunogeni pripravak koji sadrži adjuvans - Google Patents
Imunogeni pripravak koji sadrži adjuvans Download PDFInfo
- Publication number
- HRP20120136T1 HRP20120136T1 HR20120136T HRP20120136T HRP20120136T1 HR P20120136 T1 HRP20120136 T1 HR P20120136T1 HR 20120136 T HR20120136 T HR 20120136T HR P20120136 T HRP20120136 T HR P20120136T HR P20120136 T1 HRP20120136 T1 HR P20120136T1
- Authority
- HR
- Croatia
- Prior art keywords
- preparation according
- adjuvant
- comes
- lipopolysaccharide
- amount
- Prior art date
Links
- 230000002163 immunogen Effects 0.000 title claims abstract 19
- 239000002671 adjuvant Substances 0.000 title claims abstract 18
- 239000000203 mixture Substances 0.000 title abstract 3
- 239000001397 quillaja saponaria molina bark Substances 0.000 claims abstract 14
- 229930182490 saponin Natural products 0.000 claims abstract 14
- 150000007949 saponins Chemical class 0.000 claims abstract 14
- 239000002158 endotoxin Substances 0.000 claims abstract 12
- 229920006008 lipopolysaccharide Polymers 0.000 claims abstract 12
- 239000002502 liposome Substances 0.000 claims abstract 3
- 241001092142 Molina Species 0.000 claims abstract 2
- 241001454523 Quillaja saponaria Species 0.000 claims abstract 2
- 235000009001 Quillaja saponaria Nutrition 0.000 claims abstract 2
- 230000000890 antigenic effect Effects 0.000 claims abstract 2
- 238000002360 preparation method Methods 0.000 claims 31
- GZQKNULLWNGMCW-PWQABINMSA-N lipid A (E. coli) Chemical class O1[C@H](CO)[C@@H](OP(O)(O)=O)[C@H](OC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC)[C@@H](NC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)[C@@H]1OC[C@@H]1[C@@H](O)[C@H](OC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H](NC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H](OP(O)(O)=O)O1 GZQKNULLWNGMCW-PWQABINMSA-N 0.000 claims 4
- 241000282412 Homo Species 0.000 claims 3
- 229930182558 Sterol Natural products 0.000 claims 3
- 150000003432 sterols Chemical class 0.000 claims 3
- 235000003702 sterols Nutrition 0.000 claims 3
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 claims 2
- 235000012000 cholesterol Nutrition 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
Classifications
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- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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GB0609902A GB0609902D0 (en) | 2006-05-18 | 2006-05-18 | Novel composition |
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GBGB0620336.8A GB0620336D0 (en) | 2006-10-12 | 2006-10-12 | Vaccine |
PCT/GB2006/004634 WO2007068907A2 (en) | 2005-12-13 | 2006-12-12 | Vaccine compositions comprising a saponin adjuvant |
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HR20120136T HRP20120136T1 (hr) | 2005-12-13 | 2012-02-10 | Imunogeni pripravak koji sadrži adjuvans |
HRP20131057TT HRP20131057T1 (hr) | 2005-12-13 | 2013-11-06 | Cjepivni pripravci koji sadrže saponin kao adjuvans |
HRP20140484TT HRP20140484T1 (hr) | 2005-12-13 | 2014-05-28 | Cjepivni pripravci koji sadrže saponinski adjuvans |
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HRP20131057TT HRP20131057T1 (hr) | 2005-12-13 | 2013-11-06 | Cjepivni pripravci koji sadrže saponin kao adjuvans |
HRP20140484TT HRP20140484T1 (hr) | 2005-12-13 | 2014-05-28 | Cjepivni pripravci koji sadrže saponinski adjuvans |
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