BRPI0619795B8 - composição imunogênica, composição adjuvante, e, uso de uma composição imunogênica e um adjuvante - Google Patents

composição imunogênica, composição adjuvante, e, uso de uma composição imunogênica e um adjuvante

Info

Publication number
BRPI0619795B8
BRPI0619795B8 BRPI0619795A BRPI0619795A BRPI0619795B8 BR PI0619795 B8 BRPI0619795 B8 BR PI0619795B8 BR PI0619795 A BRPI0619795 A BR PI0619795A BR PI0619795 A BRPI0619795 A BR PI0619795A BR PI0619795 B8 BRPI0619795 B8 BR PI0619795B8
Authority
BR
Brazil
Prior art keywords
adjuvant
composition
immunogenic composition
lipopolysaccharide
present
Prior art date
Application number
BRPI0619795A
Other languages
English (en)
Inventor
Vandepapeliere Pierre
Original Assignee
Glaxosmithkline Biologicals Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37876836&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0619795(B8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB0525321.6A external-priority patent/GB0525321D0/en
Priority claimed from GB0609902A external-priority patent/GB0609902D0/en
Priority claimed from GB0620337A external-priority patent/GB0620337D0/en
Priority claimed from GBGB0620336.8A external-priority patent/GB0620336D0/en
Application filed by Glaxosmithkline Biologicals Sa filed Critical Glaxosmithkline Biologicals Sa
Publication of BRPI0619795A2 publication Critical patent/BRPI0619795A2/pt
Publication of BRPI0619795B1 publication Critical patent/BRPI0619795B1/pt
Publication of BRPI0619795B8 publication Critical patent/BRPI0619795B8/pt

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Abstract

composição imunogênica, composição adjuvante, e, uso de um antígeno ou sua preparação antigênica e um adjuvante. a presente invenção fornece uma dose humana de uma composição imunogênica compreendendo um antígeno ou preparação antigênica, em combinação com um adjuvante, adjuvante este compreendendo uma fração de saponina imunologicamente ativa, derivada da casca de quiliaja saponaria molina, apresentada na forma de um lipossoma e um lipopolissacarídeo, em que dita fração de saponina e dito lipopolissacarídeo estão ambos presentes em dita dose humana em um nível abaixo de 30 (mi)g. a presente invenção fornece ainda uma composição adjuvante em um volume adequado para dose humana, compreendendo entre 1 e 30 (mi)g de um lipopolissacarídeo e entre 1 e 30 (mi)g de uma fração de saponina imunologicamente ativa, apresentada na forma de um lipossoma.
BRPI0619795A 2005-12-13 2006-12-12 composição imunogênica, composição adjuvante, e, uso de uma composição imunogênica e um adjuvante BRPI0619795B8 (pt)

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GBGB0525321.6A GB0525321D0 (en) 2005-12-13 2005-12-13 Novel compositions
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GB0609902A GB0609902D0 (en) 2006-05-18 2006-05-18 Novel composition
GB0620337.6 2006-10-12
GB0620337A GB0620337D0 (en) 2006-10-12 2006-10-12 Vaccine
GBGB0620336.8A GB0620336D0 (en) 2006-10-12 2006-10-12 Vaccine
GB0620336.8 2006-10-12
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