MX2020005480A - Extraccion de saponina. - Google Patents

Extraccion de saponina.

Info

Publication number
MX2020005480A
MX2020005480A MX2020005480A MX2020005480A MX2020005480A MX 2020005480 A MX2020005480 A MX 2020005480A MX 2020005480 A MX2020005480 A MX 2020005480A MX 2020005480 A MX2020005480 A MX 2020005480A MX 2020005480 A MX2020005480 A MX 2020005480A
Authority
MX
Mexico
Prior art keywords
saponin extraction
component
main peak
extracts
absorbance
Prior art date
Application number
MX2020005480A
Other languages
English (en)
Inventor
Ahmad Taimour Baig
Garcia Juan Jose Diaz
Chad Austin Farrenburg
Kent Raymond Myers
Jeri Kay Sandvick
Jeb Yeatts Vandenburg
Original Assignee
Glaxosmithkline Biologicals Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Biologicals Sa filed Critical Glaxosmithkline Biologicals Sa
Publication of MX2020005480A publication Critical patent/MX2020005480A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Virology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Extractos acuosos crudos de Quillaja saponaria Molina que contienen al menos el pico principal QS-21 y el componente 2018, en donde la relación del componente 2018/pico principal QS-21 es = 0.075, medido por medio de la absorbancia UV a 214 nm, métodos para obtener dichos extractos y aspectos relacionados.
MX2020005480A 2017-12-01 2018-11-30 Extraccion de saponina. MX2020005480A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762593555P 2017-12-01 2017-12-01
EP17209796 2017-12-21
PCT/EP2018/083233 WO2019106191A1 (en) 2017-12-01 2018-11-30 Saponin extraction

Publications (1)

Publication Number Publication Date
MX2020005480A true MX2020005480A (es) 2020-12-07

Family

ID=64664709

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020005480A MX2020005480A (es) 2017-12-01 2018-11-30 Extraccion de saponina.

Country Status (9)

Country Link
US (3) US11744890B2 (es)
EP (1) EP3717005A1 (es)
JP (2) JP2021504429A (es)
CN (1) CN111372604A (es)
BR (1) BR112020010635A2 (es)
CA (1) CA3083059A1 (es)
CL (1) CL2020001439A1 (es)
MX (1) MX2020005480A (es)
WO (1) WO2019106191A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3717005A1 (en) 2017-12-01 2020-10-07 GlaxoSmithKline Biologicals S.A. Saponin extraction
BR112020010790A2 (pt) 2017-12-01 2020-11-10 Glaxosmithkline Biologicals S.A. purificação da saponina
US20220235095A1 (en) * 2019-06-05 2022-07-28 Glaxosmithkline Biologicals Sa Saponin purification

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5057540A (en) * 1987-05-29 1991-10-15 Cambridge Biotech Corporation Saponin adjuvant
CA1331443C (en) 1987-05-29 1994-08-16 Charlotte A. Kensil Saponin adjuvant
CA2154488C (en) * 1993-01-22 2009-10-13 Philip O. Livingston Ganglioside-klh conjugate vaccines with qs-21
KR0184779B1 (ko) * 1995-04-13 1999-04-01 성재갑 퀼라야 사포나리아 몰리나로부터 분리정제된 사포닌 변이체, 이의 분리정제 방법 및 이를 함유하는 백신 제형
DK0952771T3 (da) * 1996-12-02 2008-05-19 Antigenics Inc Hidtil ukendte saponinpræparater og anvendelser deraf
US6231859B1 (en) 1996-12-02 2001-05-15 Aquila Biopharmaceuticals, Inc. Saponin adjuvant compositions
CA2328946C (en) 1998-04-17 2008-02-12 Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Agriculture And Agri-Food Canada Process for recovery and purification of saponins and sapogenins from quinoa (chenopodium quinoa)
TWI457133B (zh) 2005-12-13 2014-10-21 Glaxosmithkline Biolog Sa 新穎組合物
GB0910046D0 (en) 2009-06-10 2009-07-22 Glaxosmithkline Biolog Sa Novel compositions
GB201213364D0 (en) 2012-07-27 2012-09-12 Glaxosmithkline Biolog Sa Purification process
WO2019025520A1 (en) 2017-08-04 2019-02-07 Ventana Medical Systems, Inc. COLOR DEMIXING WITH DIFFUSION CORRECTION
CN111065849B (zh) * 2017-09-08 2022-02-01 宝洁公司 侧切断活塞阀门组件
EP3717005A1 (en) 2017-12-01 2020-10-07 GlaxoSmithKline Biologicals S.A. Saponin extraction
BR112020010790A2 (pt) 2017-12-01 2020-11-10 Glaxosmithkline Biologicals S.A. purificação da saponina

Also Published As

Publication number Publication date
BR112020010635A2 (pt) 2020-11-10
JP2021504429A (ja) 2021-02-15
US20230355752A1 (en) 2023-11-09
CL2020001439A1 (es) 2021-02-19
US20200323980A1 (en) 2020-10-15
CA3083059A1 (en) 2019-06-06
US20240024467A1 (en) 2024-01-25
WO2019106191A1 (en) 2019-06-06
EP3717005A1 (en) 2020-10-07
US11744890B2 (en) 2023-09-05
CN111372604A (zh) 2020-07-03
JP2023182592A (ja) 2023-12-26

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