HK64492A - Imidazoquinoline derivatives - Google Patents

Imidazoquinoline derivatives

Info

Publication number
HK64492A
HK64492A HK644/92A HK64492A HK64492A HK 64492 A HK64492 A HK 64492A HK 644/92 A HK644/92 A HK 644/92A HK 64492 A HK64492 A HK 64492A HK 64492 A HK64492 A HK 64492A
Authority
HK
Hong Kong
Prior art keywords
imidazoquinoline derivatives
imidazoquinoline
derivatives
Prior art date
Application number
HK644/92A
Other languages
English (en)
Inventor
Nicholas A Meanwell
John J Wright
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of HK64492A publication Critical patent/HK64492A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK644/92A 1985-04-25 1992-08-27 Imidazoquinoline derivatives HK64492A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72686985A 1985-04-25 1985-04-25
US06/832,212 US4668686A (en) 1985-04-25 1986-02-26 Imidazoquinoline antithrombrogenic cardiotonic agents

Publications (1)

Publication Number Publication Date
HK64492A true HK64492A (en) 1992-09-04

Family

ID=27111398

Family Applications (1)

Application Number Title Priority Date Filing Date
HK644/92A HK64492A (en) 1985-04-25 1992-08-27 Imidazoquinoline derivatives

Country Status (32)

Country Link
US (1) US4668686A (cs)
KR (1) KR940000828B1 (cs)
CN (1) CN1016175B (cs)
AT (1) AT390257B (cs)
AU (1) AU592983B2 (cs)
BE (1) BE904671A (cs)
CA (1) CA1298836C (cs)
CH (1) CH675722A5 (cs)
CY (1) CY1641A (cs)
DE (1) DE3614132A1 (cs)
DK (3) DK164868C (cs)
EG (1) EG18104A (cs)
ES (3) ES8708229A1 (cs)
FI (1) FI83316C (cs)
FR (1) FR2581065B1 (cs)
GB (1) GB2174987B (cs)
GR (1) GR861086B (cs)
HK (1) HK64492A (cs)
HU (1) HU195813B (cs)
IL (1) IL78581A0 (cs)
IT (1) IT1215651B (cs)
LU (1) LU86406A1 (cs)
MY (1) MY102086A (cs)
NL (1) NL8601053A (cs)
NO (1) NO163406C (cs)
NZ (1) NZ215885A (cs)
OA (1) OA08242A (cs)
PT (1) PT82460B (cs)
SE (1) SE461468B (cs)
SG (1) SG29092G (cs)
SU (3) SU1450746A3 (cs)
YU (1) YU46054B (cs)

Families Citing this family (45)

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US4775674A (en) * 1986-05-23 1988-10-04 Bristol-Myers Company Imidazoquinolinylether derivatives useful as phosphodiesterase and blood aggregation inhibitors
US4701459A (en) * 1986-07-08 1987-10-20 Bristol-Myers Company 7-amino-1,3-dihydro-2H-imidazo[4,5-b]quinolin 2-ones and method for inhibiting phosphodiesterase and blood platelet aggregation
US4803210A (en) * 1987-05-29 1989-02-07 Merrell Dow Pharmaceuticals Inc. Cardiotonic tricyclic oxazolones
US4743607A (en) * 1987-05-29 1988-05-10 Merrell Dow Pharmaceuticals Inc. Cardiotonic tricyclic imidazolones
US4943573A (en) * 1989-11-01 1990-07-24 Bristol-Myers Squibb Company Imidazo[4,5-b]quinolinyloxyalkanoic acid amides with enhanced water solubility
DE4035854C2 (de) * 1990-11-10 1996-10-02 Daimler Benz Ag Vorrichtung zum Fangen und Ableiten des von einem Fahrzeugrad hochgeschleuderten Spritzwassers
PH31245A (en) * 1991-10-30 1998-06-18 Janssen Pharmaceutica Nv 1,3-Dihydro-2H-imidazoÄ4,5-BÜ-quinolin-2-one derivatives.
US5348960A (en) * 1992-04-03 1994-09-20 Bristol-Myers Squibb Company Imidazo[4,5-b]quinolinyl oxy alkyl tetrazolyl piperidine derivatives
US5208237A (en) * 1992-04-03 1993-05-04 Bristol-Meyers Squibb Company 7-oxypropylsulfonamido-imidazo[4,5-b]quinolin-2-ones
US5552267A (en) * 1992-04-03 1996-09-03 The Trustees Of Columbia University In The City Of New York Solution for prolonged organ preservation
US5196428A (en) * 1992-04-03 1993-03-23 Bristol-Myers Squibb Company Imidazo[4,5-b]qinolinyl oxy alkyl ureas
US5158958A (en) * 1992-04-03 1992-10-27 Bristol-Myers Squibb Company Imidazo[4,5-b]quinolinyl oxy alkyl sulfonyl piperidine derivatives
TW593317B (en) * 1993-06-21 2004-06-21 Janssen Pharmaceutica Nv Positive cardiac inotropic and lusitropic pyrroloquinolinone derivatives
CZ3696A3 (en) * 1993-07-06 1997-06-11 Pfizer Bicyclic tetrahydropyrazolepyridines per se and for treating diseases, and pharmaceutical compositions based thereon
TW574214B (en) * 1994-06-08 2004-02-01 Pfizer Corticotropin releasing factor antagonists
US6664264B2 (en) * 2000-12-08 2003-12-16 3M Innovative Properties Company Thioether substituted imidazoquinolines
BRPI0412902A (pt) 2003-08-12 2006-09-26 3M Innovative Properties Co compostos contendo imidazo substituìdo por oxima
CA2536136C (en) 2003-08-27 2012-10-30 3M Innovative Properties Company Aryloxy and arylalkyleneoxy substituted imidazoquinolines
AU2004270201A1 (en) 2003-09-05 2005-03-17 3M Innovative Properties Company Treatment for CD5+ B cell lymphoma
CN1897948A (zh) 2003-10-03 2007-01-17 3M创新有限公司 烷氧基取代的咪唑并喹啉
US7544697B2 (en) 2003-10-03 2009-06-09 Coley Pharmaceutical Group, Inc. Pyrazolopyridines and analogs thereof
JP2007511527A (ja) 2003-11-14 2007-05-10 スリーエム イノベイティブ プロパティズ カンパニー オキシム置換イミダゾ環化合物
EP1682544A4 (en) * 2003-11-14 2009-05-06 3M Innovative Properties Co HYDROXYLAMINE SUBSTITUTED IMIDAZO RING COMPOUNDS
RU2409576C2 (ru) 2003-11-25 2011-01-20 3М Инновейтив Пропертиз Компани Системы, содержащие имидазольное кольцо с заместителями, и способы их получения
US8802853B2 (en) 2003-12-29 2014-08-12 3M Innovative Properties Company Arylalkenyl and arylalkynyl substituted imidazoquinolines
US8735421B2 (en) 2003-12-30 2014-05-27 3M Innovative Properties Company Imidazoquinolinyl sulfonamides
US8697873B2 (en) 2004-03-24 2014-04-15 3M Innovative Properties Company Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines
WO2005123080A2 (en) 2004-06-15 2005-12-29 3M Innovative Properties Company Nitrogen-containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines
WO2006038923A2 (en) 2004-06-18 2006-04-13 3M Innovative Properties Company Aryl substituted imidazonaphthyridines
US8026366B2 (en) 2004-06-18 2011-09-27 3M Innovative Properties Company Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines
WO2006065280A2 (en) 2004-06-18 2006-06-22 3M Innovative Properties Company Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and methods
CA2580343A1 (en) * 2004-09-14 2006-03-23 Novartis Vaccines And Diagnostics, Inc. Imidazoquinoline compounds
AU2005326708C1 (en) 2004-12-30 2012-08-30 3M Innovative Properties Company Substituted chiral fused [1,2]imidazo[4,5-c] ring compounds
AU2005322898B2 (en) 2004-12-30 2011-11-24 3M Innovative Properties Company Chiral fused (1,2)imidazo(4,5-c) ring compounds
WO2006084251A2 (en) 2005-02-04 2006-08-10 Coley Pharmaceutical Group, Inc. Aqueous gel formulations containing immune reponse modifiers
AU2006213746A1 (en) 2005-02-11 2006-08-17 Coley Pharmaceutical Group, Inc. Oxime and hydroxylamine substituted imidazo(4,5-c) ring compounds and methods
US7943636B2 (en) 2005-04-01 2011-05-17 3M Innovative Properties Company 1-substituted pyrazolo (3,4-C) ring compounds as modulators of cytokine biosynthesis for the treatment of viral infections and neoplastic diseases
WO2006107853A2 (en) 2005-04-01 2006-10-12 Coley Pharmaceutical Group, Inc. Pyrazolopyridine-1,4-diamines and analogs thereof
WO2008008432A2 (en) 2006-07-12 2008-01-17 Coley Pharmaceutical Group, Inc. Substituted chiral fused( 1,2) imidazo (4,5-c) ring compounds and methods
US8227603B2 (en) 2006-08-01 2012-07-24 Cytokinetics, Inc. Modulating skeletal muscle
US8299248B2 (en) 2006-08-02 2012-10-30 Cytokinetics, Incorporated Certain 1H-imidazo[4,5-b]pyrazin-2(3H)-ones and 1H-imidazo[4,5-b]pyrazin-2-ols and methods for their use
ES2558517T3 (es) 2006-08-02 2016-02-04 Cytokinetics, Inc. Ciertas entidades químicas, composiciones y métodos que comprenden imidazopirimidinas
EP2139478A4 (en) * 2007-03-30 2010-05-05 Cytokinetics Inc CHEMICAL ENTITIES, COMPOSITIONS AND METHODS
CN109316480A (zh) 2011-07-13 2019-02-12 赛特凯恩蒂克公司 组合als疗法
CN120265631A (zh) * 2023-01-13 2025-07-04 上海超阳药业有限公司 喹啉酮化合物和萘啶酮化合物及其用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932407A (en) * 1973-11-19 1976-01-13 Bristol-Myers Company Optionally substituted 1,2,3,5-tetrahydroimidezo(2,1-b)-quinazolin-2-ones and 6(H)-1,2,3,4-tetrahydropyimido(2,1-b)quinazolin-2-ones

Also Published As

Publication number Publication date
HUT42089A (en) 1987-06-29
NO163406C (no) 1990-05-23
SU1470192A3 (ru) 1989-03-30
NO861617L (no) 1986-10-27
FR2581065B1 (fr) 1990-02-02
IT8620206A0 (it) 1986-04-24
SE461468B (sv) 1990-02-19
CN1016175B (zh) 1992-04-08
MY102086A (en) 1992-03-31
ATA112186A (de) 1989-09-15
ES8708229A1 (es) 1987-10-01
SE8601907L (sv) 1986-10-26
DK165249B (da) 1992-10-26
SG29092G (en) 1992-05-15
YU46054B (sh) 1992-12-21
BE904671A (fr) 1986-10-24
SU1450746A3 (ru) 1989-01-07
FI83316C (fi) 1991-06-25
SE8601907D0 (sv) 1986-04-24
SU1560056A3 (ru) 1990-04-23
CY1641A (en) 1992-11-06
CA1298836C (en) 1992-04-14
DK80291A (da) 1991-04-30
CH675722A5 (cs) 1990-10-31
GR861086B (en) 1986-09-01
YU116787A (en) 1988-04-30
DK165248C (da) 1993-03-22
DK81091A (da) 1991-05-01
NO163406B (no) 1990-02-12
DK190986D0 (da) 1986-04-24
DK165249C (da) 1993-03-22
OA08242A (en) 1987-10-30
ES554336A0 (es) 1987-10-01
HU195813B (en) 1988-07-28
EG18104A (en) 1992-09-30
DK165248B (da) 1992-10-26
LU86406A1 (fr) 1986-11-05
DK190986A (da) 1986-10-26
DK164868B (da) 1992-08-31
GB8610037D0 (en) 1986-05-29
ES557551A0 (es) 1988-02-16
FI861684A0 (fi) 1986-04-22
FI83316B (fi) 1991-03-15
GB2174987A (en) 1986-11-19
DE3614132A1 (de) 1986-11-27
ES557552A0 (es) 1988-07-16
US4668686A (en) 1987-05-26
AU5641386A (en) 1986-10-30
AU592983B2 (en) 1990-02-01
KR940000828B1 (ko) 1994-02-02
PT82460B (pt) 1988-11-30
DK164868C (da) 1993-01-11
FI861684L (fi) 1986-10-26
IL78581A0 (en) 1986-08-31
GB2174987B (en) 1989-08-02
DK81091D0 (da) 1991-05-01
DK80291D0 (da) 1991-04-30
ES8801829A1 (es) 1988-02-16
IT1215651B (it) 1990-02-22
NZ215885A (en) 1989-04-26
ES8802521A1 (es) 1988-07-16
FR2581065A1 (fr) 1986-10-31
NL8601053A (nl) 1986-11-17
PT82460A (en) 1986-05-01
CN86102747A (zh) 1987-02-04
KR860008177A (ko) 1986-11-12
AT390257B (de) 1990-04-10

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