HK1042521B - 生產重組白蛋白的方法 - Google Patents

生產重組白蛋白的方法

Info

Publication number
HK1042521B
HK1042521B HK02104220.2A HK02104220A HK1042521B HK 1042521 B HK1042521 B HK 1042521B HK 02104220 A HK02104220 A HK 02104220A HK 1042521 B HK1042521 B HK 1042521B
Authority
HK
Hong Kong
Prior art keywords
albumin
recombinant albumin
cell
producing recombinant
coding sequence
Prior art date
Application number
HK02104220.2A
Other languages
English (en)
Other versions
HK1042521A1 (en
Inventor
亨德里克‧范厄克
戴維‧J‧米德
菲利普‧H‧莫頓
安德魯‧J‧卡特賴特
賈森‧卡梅倫
戴維‧J‧巴蘭斯
米歇爾‧G‧J‧格蘭德喬治
斯蒂芬‧貝雷曾科
約翰‧R‧伍德羅
達雷爾‧斯利普
Original Assignee
Albumedix Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Albumedix Ltd filed Critical Albumedix Ltd
Publication of HK1042521A1 publication Critical patent/HK1042521A1/xx
Publication of HK1042521B publication Critical patent/HK1042521B/zh

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3804—Affinity chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
    • B01D15/361—Ion-exchange
    • B01D15/362—Cation-exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
    • B01D15/361—Ion-exchange
    • B01D15/363—Anion-exchange
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Glass Compositions (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
HK02104220.2A 1999-01-30 2002-06-04 生產重組白蛋白的方法 HK1042521B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9902000A GB9902000D0 (en) 1999-01-30 1999-01-30 Process
PCT/GB2000/000257 WO2000044772A2 (en) 1999-01-30 2000-01-31 Human serum albumin

Publications (2)

Publication Number Publication Date
HK1042521A1 HK1042521A1 (en) 2002-08-16
HK1042521B true HK1042521B (zh) 2005-10-07

Family

ID=10846743

Family Applications (2)

Application Number Title Priority Date Filing Date
HK07101272A HK1096691A1 (en) 1999-01-30 2002-06-04 Process for the preparation of a highly pure albumin solution
HK02104220.2A HK1042521B (zh) 1999-01-30 2002-06-04 生產重組白蛋白的方法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK07101272A HK1096691A1 (en) 1999-01-30 2002-06-04 Process for the preparation of a highly pure albumin solution

Country Status (16)

Country Link
US (3) US7993877B2 (zh)
EP (3) EP2272961A1 (zh)
JP (3) JP4586150B2 (zh)
KR (2) KR100886554B1 (zh)
CN (4) CN1810834B (zh)
AT (1) ATE416254T1 (zh)
AU (2) AU763899B2 (zh)
CA (1) CA2359705C (zh)
DE (1) DE60040967D1 (zh)
DK (1) DK2048234T3 (zh)
ES (1) ES2317827T3 (zh)
GB (1) GB9902000D0 (zh)
HK (2) HK1096691A1 (zh)
MX (1) MXPA01007719A (zh)
SG (2) SG119194A1 (zh)
WO (1) WO2000044772A2 (zh)

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US20150056654A1 (en) 2015-02-26
WO2000044772A2 (en) 2000-08-03
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JP5474661B2 (ja) 2014-04-16
US20090171070A1 (en) 2009-07-02
KR100577493B1 (ko) 2006-05-10
EP1149163A2 (en) 2001-10-31
AU2120700A (en) 2000-08-18
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