GEP20053420B - Sustained Release Ranolanolazine Formulation - Google Patents

Sustained Release Ranolanolazine Formulation

Info

Publication number
GEP20053420B
GEP20053420B GE4322A GEAP1999004322A GEP20053420B GE P20053420 B GEP20053420 B GE P20053420B GE 4322 A GE4322 A GE 4322A GE AP1999004322 A GEAP1999004322 A GE AP1999004322A GE P20053420 B GEP20053420 B GE P20053420B
Authority
GE
Georgia
Prior art keywords
ranolanolazine
formulation
sustained release
ranolazine
essence
Prior art date
Application number
GE4322A
Other languages
English (en)
Inventor
Andrew A Wolff
Fiona Baker
John Richard Langridge
Original Assignee
Cv Therapeutics Inc
Syntex Usa Llk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26796494&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GEP20053420(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cv Therapeutics Inc, Syntex Usa Llk filed Critical Cv Therapeutics Inc
Publication of GEP20053420B publication Critical patent/GEP20053420B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
GE4322A 1998-09-10 1999-09-09 Sustained Release Ranolanolazine Formulation GEP20053420B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9980498P 1998-09-10 1998-09-10
US09/321,522 US6303607B1 (en) 1998-09-10 1999-05-27 Method for administering a sustained release ranolanolazine formulation

Publications (1)

Publication Number Publication Date
GEP20053420B true GEP20053420B (en) 2005-01-25

Family

ID=26796494

Family Applications (1)

Application Number Title Priority Date Filing Date
GE4322A GEP20053420B (en) 1998-09-10 1999-09-09 Sustained Release Ranolanolazine Formulation

Country Status (33)

Country Link
US (14) US6303607B1 (enExample)
EP (3) EP1527779A1 (enExample)
JP (2) JP3745621B2 (enExample)
KR (1) KR100475759B1 (enExample)
CN (2) CN1193757C (enExample)
AR (3) AR022085A1 (enExample)
AT (2) ATE217794T1 (enExample)
AU (4) AU744071B2 (enExample)
BR (2) BR9913626A (enExample)
CA (2) CA2343376C (enExample)
CY (1) CY2008020I2 (enExample)
CZ (2) CZ301375B6 (enExample)
DE (3) DE69901570T2 (enExample)
DK (2) DK1096937T3 (enExample)
ES (2) ES2234302T3 (enExample)
FR (1) FR09C0001I2 (enExample)
GE (1) GEP20053420B (enExample)
HK (1) HK1044284B (enExample)
HU (2) HUP0104088A3 (enExample)
IL (6) IL141892A0 (enExample)
LU (1) LU91504I2 (enExample)
MX (2) MXPA01002599A (enExample)
NL (1) NL300371I2 (enExample)
NO (4) NO320986B1 (enExample)
NZ (2) NZ510386A (enExample)
PL (3) PL202207B1 (enExample)
PT (2) PT1096937E (enExample)
RU (2) RU2207856C2 (enExample)
SI (2) SI1096937T1 (enExample)
TR (2) TR200101261T2 (enExample)
TW (1) TWI241911B (enExample)
UA (2) UA67793C2 (enExample)
WO (2) WO2000013687A2 (enExample)

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US6303607B1 (en) * 1998-09-10 2001-10-16 Cv Therapeutics, Inc. Method for administering a sustained release ranolanolazine formulation
EP1259230A2 (en) * 2000-02-18 2002-11-27 Cv Therapeutics, Inc. Partial fatty acid oxidation inhibitors in the treatment of congestive heart failure
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US8101209B2 (en) * 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
US20030220344A1 (en) * 2002-04-04 2003-11-27 Luiz Belardinelli Method of treating arrhythmias
US20080109040A1 (en) * 2002-04-04 2008-05-08 Luiz Belardinelli Method of treating arrhythmias
DE60323474D1 (de) * 2002-04-09 2008-10-23 Flamel Tech Sa Orale pharmazeutische formulierung in form einer wässrigen suspension von mikrokapseln zur modifizierten freisetzung von amoxicillin
MXPA04009968A (es) 2002-04-09 2004-12-13 Flamel Tech Sa Formulacion farmaceutica oral bajo forma de suspension acuosa de microcapsulas que permiten la liberacion modificada de principio (s) activo (s).
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Also Published As

Publication number Publication date
NO2009005I1 (no) 2009-03-16
DE69901570T2 (de) 2003-01-09
DK1109558T3 (da) 2002-08-26
US20060147521A1 (en) 2006-07-06
AU6142599A (en) 2000-03-27
WO2000013687A3 (en) 2000-06-29
US6864258B2 (en) 2005-03-08
HUP0104088A3 (en) 2002-12-28
US6562826B1 (en) 2003-05-13
DE122008000065I1 (de) 2009-04-09
NO20054324L (no) 2001-04-30
AU2008207703A1 (en) 2008-09-25
US6369062B1 (en) 2002-04-09
DE69922964T2 (de) 2005-12-08
NO20011192D0 (no) 2001-03-08
US20030099705A1 (en) 2003-05-29
SI1096937T1 (en) 2005-04-30
NO20011191D0 (no) 2001-03-08
PT1096937E (pt) 2005-04-29
US20050153982A1 (en) 2005-07-14
FR09C0001I2 (enExample) 2009-12-18
NO320986B1 (no) 2006-02-20
WO2000013686A3 (en) 2000-07-06
US6852724B2 (en) 2005-02-08
EP1527779A1 (en) 2005-05-04
NZ510386A (en) 2003-08-29
US20060217397A1 (en) 2006-09-28
LU91504I9 (enExample) 2019-01-02
CA2343376C (en) 2007-01-09
AU2008207707A1 (en) 2008-09-25
IL141892A0 (en) 2002-03-10
CA2342390A1 (en) 2000-03-16
CN1354665A (zh) 2002-06-19
IL175371A0 (en) 2006-09-05
NO319434B1 (no) 2005-08-15
US20030166659A1 (en) 2003-09-04
EP1109558A2 (en) 2001-06-27
AR052921A1 (es) 2007-04-11
US6620814B2 (en) 2003-09-16
JP2006096757A (ja) 2006-04-13
EP1096937B1 (en) 2004-12-29
NO20011191L (no) 2001-04-30
TR200101261T2 (tr) 2002-05-21
HK1044284B (zh) 2005-07-15
AR022085A1 (es) 2002-09-04
RU2214233C2 (ru) 2003-10-20
IL141892A (en) 2006-08-20
MXPA01002598A (es) 2002-04-08
NL300371I2 (nl) 2009-10-01
HUP0104088A2 (hu) 2002-05-29
SI1109558T1 (en) 2002-10-31
ATE217794T1 (de) 2002-06-15
US6617328B2 (en) 2003-09-09
MXPA01002599A (es) 2005-02-17
CN1211086C (zh) 2005-07-20
PT1109558E (pt) 2002-10-31
WO2000013687A2 (en) 2000-03-16
CY2008020I1 (el) 2010-07-28
PL196668B1 (pl) 2008-01-31
PL202207B1 (pl) 2009-06-30
TWI241911B (en) 2005-10-21
CN1193757C (zh) 2005-03-23
RU2207856C2 (ru) 2003-07-10
AU760435B2 (en) 2003-05-15
HUP0103844A3 (en) 2002-11-28
TR200101262T2 (tr) 2001-12-21
IL141893A (en) 2008-08-07
JP2002524416A (ja) 2002-08-06
CA2342390C (en) 2006-08-29
CZ2001879A3 (cs) 2001-08-15
ES2177346T3 (es) 2002-12-01
PL196263B1 (pl) 2007-12-31
KR100475759B1 (ko) 2005-03-10
US20040029890A1 (en) 2004-02-12
IL141893A0 (en) 2002-03-10
UA75027C2 (uk) 2006-03-15
CA2343376A1 (en) 2000-03-16
UA67793C2 (uk) 2004-07-15
PL348249A1 (en) 2002-05-20
US20050059667A1 (en) 2005-03-17
NO2009005I2 (enExample) 2010-06-28
ATE285774T1 (de) 2005-01-15
US6503911B2 (en) 2003-01-07
NZ510384A (en) 2002-10-25
HK1040060A1 (en) 2002-05-24
CN1321088A (zh) 2001-11-07
NL300371I1 (nl) 2009-02-02
AU744071B2 (en) 2002-02-14
CZ2001880A3 (cs) 2001-08-15
US20040097514A1 (en) 2004-05-20
US6303607B1 (en) 2001-10-16
DE69922964D1 (de) 2005-02-03
PL347073A1 (en) 2002-03-11
WO2000013686A2 (en) 2000-03-16
US20020004506A1 (en) 2002-01-10
US6525057B2 (en) 2003-02-25
ES2234302T3 (es) 2005-06-16
BR9913626A (pt) 2001-12-04
US20020090396A1 (en) 2002-07-11
LU91504I2 (fr) 2009-02-03
BR9913553A (pt) 2001-10-23
US20030100566A1 (en) 2003-05-29
CY2008020I2 (el) 2010-07-28
EP1109558B1 (en) 2002-05-22
HU224215B1 (hu) 2005-06-28
JP3745621B2 (ja) 2006-02-15
CZ301375B6 (cs) 2010-02-03
EP1096937A2 (en) 2001-05-09
NO20011192L (no) 2001-04-30
HUP0103844A2 (hu) 2002-04-29
KR20010089874A (ko) 2001-10-12
EP1096937B9 (en) 2007-02-28
CZ301341B6 (cs) 2010-01-20
DK1096937T3 (da) 2005-05-09
DE69901570D1 (de) 2002-06-27
IL180864A0 (en) 2007-07-04
FR09C0001I1 (enExample) 2009-02-27
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AR053440A2 (es) 2007-05-09
HK1044284A1 (en) 2002-10-18

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