HUP0103844A2 - Késleltetett felszabadulású ranolazin-készítmények - Google Patents

Késleltetett felszabadulású ranolazin-készítmények

Info

Publication number
HUP0103844A2
HUP0103844A2 HU0103844A HUP0103844A HUP0103844A2 HU P0103844 A2 HUP0103844 A2 HU P0103844A2 HU 0103844 A HU0103844 A HU 0103844A HU P0103844 A HUP0103844 A HU P0103844A HU P0103844 A2 HUP0103844 A2 HU P0103844A2
Authority
HU
Hungary
Prior art keywords
release
sustained release
ranolazine
dosage form
release ranolazine
Prior art date
Application number
HU0103844A
Other languages
English (en)
Inventor
Fiona Baker
John Langridge
Andrew A. Wolff
Original Assignee
Cv Therapeutics, Inc.
Syntex (Usa) Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26796494&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP0103844(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cv Therapeutics, Inc., Syntex (Usa) Llc filed Critical Cv Therapeutics, Inc.
Publication of HUP0103844A2 publication Critical patent/HUP0103844A2/hu
Publication of HUP0103844A3 publication Critical patent/HUP0103844A3/hu
Publication of HU224215B1 publication Critical patent/HU224215B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

A tal lm ny t rgya gyógy szati adagol si forma, amely legal bbk"rülbelül 50 t"meg% ranolazint és legal bb egy pH-függő k"tőanyagottartalmaz, amely megakad lyozza a ranolazin felszabadul s t akésleltetett felszabadul sú adagol si form ból, amikor a késleltetettfelszabadul sú adagol si forma a gyomor pH-értékével rendelkező, vizesk"zeg hat sa al kerül, és amely elősegíti a ranolazin ter pi smennyiségének a felszabadul s t k"rülbelül 4,5-nél magasabb pH-értékűvizes oldatban. A gyógy szati adagol si forma előny"sen préselttabletta form jú. Ó
HU0103844A 1998-09-10 1999-09-09 Késleltetett felszabadulású ranolazinkészítmények HU224215B1 (hu)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9980498P 1998-09-10 1998-09-10
US09/321,522 US6303607B1 (en) 1998-09-10 1999-05-27 Method for administering a sustained release ranolanolazine formulation
PCT/US1999/020967 WO2000013686A2 (en) 1998-09-10 1999-09-09 Sustained release ranolazine formulations

Publications (3)

Publication Number Publication Date
HUP0103844A2 true HUP0103844A2 (hu) 2002-04-29
HUP0103844A3 HUP0103844A3 (en) 2002-11-28
HU224215B1 HU224215B1 (hu) 2005-06-28

Family

ID=26796494

Family Applications (2)

Application Number Title Priority Date Filing Date
HU0103844A HU224215B1 (hu) 1998-09-10 1999-09-09 Késleltetett felszabadulású ranolazinkészítmények
HU0104088A HUP0104088A3 (en) 1998-09-10 1999-09-09 Use of sustained release ranolazine formulations

Family Applications After (1)

Application Number Title Priority Date Filing Date
HU0104088A HUP0104088A3 (en) 1998-09-10 1999-09-09 Use of sustained release ranolazine formulations

Country Status (33)

Country Link
US (14) US6303607B1 (hu)
EP (3) EP1109558B1 (hu)
JP (2) JP3745621B2 (hu)
KR (1) KR100475759B1 (hu)
CN (2) CN1211086C (hu)
AR (3) AR022085A1 (hu)
AT (2) ATE285774T1 (hu)
AU (4) AU744071B2 (hu)
BR (2) BR9913626A (hu)
CA (2) CA2342390C (hu)
CY (1) CY2008020I1 (hu)
CZ (2) CZ301375B6 (hu)
DE (3) DE69901570T2 (hu)
DK (2) DK1096937T3 (hu)
ES (2) ES2234302T3 (hu)
FR (1) FR09C0001I2 (hu)
GE (1) GEP20053420B (hu)
HK (2) HK1040060A1 (hu)
HU (2) HU224215B1 (hu)
IL (6) IL141892A0 (hu)
LU (1) LU91504I2 (hu)
MX (2) MXPA01002598A (hu)
NL (1) NL300371I2 (hu)
NO (4) NO320986B1 (hu)
NZ (2) NZ510386A (hu)
PL (3) PL202207B1 (hu)
PT (2) PT1096937E (hu)
RU (2) RU2214233C2 (hu)
SI (2) SI1109558T1 (hu)
TR (2) TR200101262T2 (hu)
TW (1) TWI241911B (hu)
UA (2) UA75027C2 (hu)
WO (2) WO2000013687A2 (hu)

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Also Published As

Publication number Publication date
HU224215B1 (hu) 2005-06-28
US6852724B2 (en) 2005-02-08
JP2006096757A (ja) 2006-04-13
PT1109558E (pt) 2002-10-31
HK1044284A1 (en) 2002-10-18
CZ301375B6 (cs) 2010-02-03
US20040029890A1 (en) 2004-02-12
IL141893A (en) 2008-08-07
CN1211086C (zh) 2005-07-20
US20060147521A1 (en) 2006-07-06
AU2008207703A1 (en) 2008-09-25
PL196263B1 (pl) 2007-12-31
AU744071B2 (en) 2002-02-14
NO20011192L (no) 2001-04-30
AU760435B2 (en) 2003-05-15
CY2008020I2 (el) 2010-07-28
SI1109558T1 (en) 2002-10-31
NZ510386A (en) 2003-08-29
MXPA01002598A (es) 2002-04-08
CA2342390A1 (en) 2000-03-16
HUP0104088A3 (en) 2002-12-28
CA2343376A1 (en) 2000-03-16
ATE285774T1 (de) 2005-01-15
BR9913626A (pt) 2001-12-04
NO20011191L (no) 2001-04-30
NO319434B1 (no) 2005-08-15
NO2009005I2 (hu) 2010-06-28
AR052921A1 (es) 2007-04-11
US6525057B2 (en) 2003-02-25
RU2207856C2 (ru) 2003-07-10
NO20054324L (no) 2001-04-30
AU6142599A (en) 2000-03-27
NO2009005I1 (no) 2009-03-16
EP1096937B1 (en) 2004-12-29
CN1193757C (zh) 2005-03-23
GEP20053420B (en) 2005-01-25
US20020090396A1 (en) 2002-07-11
DE69901570D1 (de) 2002-06-27
AR053440A2 (es) 2007-05-09
AU6036499A (en) 2000-03-27
NO20011191D0 (no) 2001-03-08
US20050059667A1 (en) 2005-03-17
ATE217794T1 (de) 2002-06-15
TR200101262T2 (tr) 2001-12-21
MXPA01002599A (es) 2005-02-17
EP1527779A1 (en) 2005-05-04
PL347073A1 (en) 2002-03-11
WO2000013686A2 (en) 2000-03-16
NO20011192D0 (no) 2001-03-08
CA2343376C (en) 2007-01-09
US6303607B1 (en) 2001-10-16
HUP0103844A3 (en) 2002-11-28
IL180864A0 (en) 2007-07-04
LU91504I2 (fr) 2009-02-03
DK1109558T3 (da) 2002-08-26
DE122008000065I1 (de) 2009-04-09
RU2214233C2 (ru) 2003-10-20
US20050153982A1 (en) 2005-07-14
US6864258B2 (en) 2005-03-08
WO2000013687A3 (en) 2000-06-29
PT1096937E (pt) 2005-04-29
PL196668B1 (pl) 2008-01-31
WO2000013687A2 (en) 2000-03-16
EP1096937B9 (en) 2007-02-28
AR022085A1 (es) 2002-09-04
WO2000013686A3 (en) 2000-07-06
NZ510384A (en) 2002-10-25
BR9913553A (pt) 2001-10-23
JP3745621B2 (ja) 2006-02-15
TR200101261T2 (tr) 2002-05-21
IL141893A0 (en) 2002-03-10
US20020004506A1 (en) 2002-01-10
CY2008020I1 (el) 2010-07-28
NL300371I2 (nl) 2009-10-01
DE69922964D1 (de) 2005-02-03
US20030100566A1 (en) 2003-05-29
US6617328B2 (en) 2003-09-09
KR100475759B1 (ko) 2005-03-10
US20030166659A1 (en) 2003-09-04
US6562826B1 (en) 2003-05-13
ES2234302T3 (es) 2005-06-16
CZ2001880A3 (cs) 2001-08-15
PL202207B1 (pl) 2009-06-30
SI1096937T1 (en) 2005-04-30
IL141892A (en) 2006-08-20
UA67793C2 (uk) 2004-07-15
DE69901570T2 (de) 2003-01-09
NL300371I1 (nl) 2009-02-02
IL175371A0 (en) 2006-09-05
TWI241911B (en) 2005-10-21
IL141892A0 (en) 2002-03-10
EP1096937A2 (en) 2001-05-09
FR09C0001I2 (hu) 2009-12-18
CZ301341B6 (cs) 2010-01-20
ES2177346T3 (es) 2002-12-01
HK1044284B (zh) 2005-07-15
FR09C0001I1 (hu) 2009-02-27
DK1096937T3 (da) 2005-05-09
CN1321088A (zh) 2001-11-07
CZ2001879A3 (cs) 2001-08-15
AU2008207707A1 (en) 2008-09-25
DE69922964T2 (de) 2005-12-08
HUP0104088A2 (hu) 2002-05-29
UA75027C2 (uk) 2006-03-15
LU91504I9 (hu) 2019-01-02
CA2342390C (en) 2006-08-29
US20030099705A1 (en) 2003-05-29
PL348249A1 (en) 2002-05-20
US20060217397A1 (en) 2006-09-28
EP1109558A2 (en) 2001-06-27
CN1354665A (zh) 2002-06-19
US6503911B2 (en) 2003-01-07
NO320986B1 (no) 2006-02-20
HK1040060A1 (en) 2002-05-24
US6620814B2 (en) 2003-09-16
EP1109558B1 (en) 2002-05-22
US6369062B1 (en) 2002-04-09
US20040097514A1 (en) 2004-05-20
KR20010089874A (ko) 2001-10-12
JP2002524416A (ja) 2002-08-06

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