FR2563832B1 - Nouveaux derives cephem, procede pour la preparation de ces nouveaux composes, compositions pharmaceutiques contenant au moins un de ces composes et intermediaires de synthese pour leur preparation - Google Patents

Nouveaux derives cephem, procede pour la preparation de ces nouveaux composes, compositions pharmaceutiques contenant au moins un de ces composes et intermediaires de synthese pour leur preparation

Info

Publication number
FR2563832B1
FR2563832B1 FR8505281A FR8505281A FR2563832B1 FR 2563832 B1 FR2563832 B1 FR 2563832B1 FR 8505281 A FR8505281 A FR 8505281A FR 8505281 A FR8505281 A FR 8505281A FR 2563832 B1 FR2563832 B1 FR 2563832B1
Authority
FR
France
Prior art keywords
preparation
compounds
pharmaceutical compositions
compositions containing
synthesis intermediates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8505281A
Other languages
English (en)
French (fr)
Other versions
FR2563832A1 (fr
Inventor
Haruhiro Yamashita
Masahisa Oka
Takayuki Naito
Jun Okumura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of FR2563832A1 publication Critical patent/FR2563832A1/fr
Application granted granted Critical
Publication of FR2563832B1 publication Critical patent/FR2563832B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/08—1,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/78—Separation; Purification; Stabilisation; Use of additives
    • C07C45/79—Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FR8505281A 1984-04-09 1985-04-05 Nouveaux derives cephem, procede pour la preparation de ces nouveaux composes, compositions pharmaceutiques contenant au moins un de ces composes et intermediaires de synthese pour leur preparation Expired FR2563832B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59794184A 1984-04-09 1984-04-09

Publications (2)

Publication Number Publication Date
FR2563832A1 FR2563832A1 (fr) 1985-11-08
FR2563832B1 true FR2563832B1 (fr) 1989-08-18

Family

ID=24393575

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8505281A Expired FR2563832B1 (fr) 1984-04-09 1985-04-05 Nouveaux derives cephem, procede pour la preparation de ces nouveaux composes, compositions pharmaceutiques contenant au moins un de ces composes et intermediaires de synthese pour leur preparation

Country Status (31)

Country Link
JP (4) JPS615084A (ru)
KR (1) KR870002166B1 (ru)
AR (1) AR244694A1 (ru)
AT (1) AT388735B (ru)
AU (2) AU580990B2 (ru)
BE (1) BE902148A (ru)
CA (3) CA1276929C (ru)
CH (1) CH669197A5 (ru)
DD (3) DD249024A5 (ru)
DE (1) DE3512225A1 (ru)
DK (1) DK155985A (ru)
ES (4) ES8607318A1 (ru)
FI (1) FI84830C (ru)
FR (1) FR2563832B1 (ru)
GB (3) GB2157293B (ru)
GR (1) GR850883B (ru)
HU (2) HU204277B (ru)
IE (2) IE58408B1 (ru)
IL (1) IL74826A (ru)
IT (1) IT1190353B (ru)
LU (1) LU85840A1 (ru)
MY (1) MY101940A (ru)
NL (1) NL192925C (ru)
NZ (1) NZ211659A (ru)
OA (1) OA07985A (ru)
PT (1) PT80246B (ru)
RU (1) RU2056425C1 (ru)
SE (4) SE466205B (ru)
SU (4) SU1436882A3 (ru)
YU (2) YU46151B (ru)
ZA (1) ZA852236B (ru)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61145186A (ja) * 1984-12-20 1986-07-02 Meiji Seika Kaisha Ltd 新規セフエム化合物及びその製造法
US4708955A (en) * 1985-06-24 1987-11-24 Bristol-Myers Company 3-(substituted)propenyl-7-aminothiazol-ylcephalosporanic acids and esters thereof
ATE114657T1 (de) * 1985-12-26 1994-12-15 Eisai Co Ltd Cephalosporin-verbindungen.
AU614723B2 (en) * 1986-10-13 1991-09-12 Eisai Co. Ltd. 3-propenylcephem derivative
IL84128A (en) * 1986-10-13 1992-12-01 Eisai Co Ltd 3-propenylcephem derivatives, their preparation and pharmaceutical compositions containing them
JPH085897B2 (ja) * 1986-11-06 1996-01-24 エーザイ株式会社 ３−プロペニルセフェム誘導体
FR2622585B1 (fr) * 1987-11-03 1991-04-19 Roussel Uclaf Nouvelles cephalosporines comportant en position 3 un radical vinyle substitue, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus
CA1339738C (en) * 1988-03-16 1998-03-17 Takashi Kamiya Process for the preparation of cephem derivatives and entermediates therefor
JPH0699449B2 (ja) * 1988-03-16 1994-12-07 エーザイ株式会社 セフェム誘導体の合成中間体
FR2655042B1 (fr) * 1989-11-29 1994-01-21 Adir Cie Nouvelles benzothiazolinones substituees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2663332B1 (fr) * 1990-06-15 1997-11-07 Roussel Uclaf Nouvelles cephalosporines comportant en position 3 un radical propenyle substitue par un ammonium quaternaire, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus.
US5126336A (en) * 1990-08-23 1992-06-30 Bristol-Myers Squibb Company Antibiotic c-3 catechol-substituted cephalosporin compounds, compositions and method of use thereof
AT396108B (de) * 1991-08-21 1993-06-25 Biochemie Gmbh Neues verfahren und neue zwischenprodukte zur herstellung von 7-aminocephalosporansaeurederivaten
JPH0741484A (ja) * 1993-07-29 1995-02-10 Katayama Seiyakushiyo:Kk セフェム化合物及び抗菌剤
KR100248851B1 (ko) * 1994-08-16 2000-04-01 이치로 키타사토 신규 세펨 유도체
WO1999067255A1 (en) 1998-06-22 1999-12-29 F. Hoffmann-La Roche Ag Propenyl cephalosporin derivatives
WO2005026176A1 (ja) 2003-09-09 2005-03-24 Nippon Chemical Industrial Co.,Ltd. ３−クロロメチル-３-セフェム誘導体の製造方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1342241A (en) * 1970-01-23 1974-01-03 Glaxo Lab Ltd Cephalosporin compounds
US4390534A (en) * 1978-12-29 1983-06-28 Fujisawa Pharmaceutical Co., Ltd. Cephem and cepham compounds
EP0025017A1 (de) * 1979-08-28 1981-03-11 Ciba-Geigy Ag Polyazathiaverbindungen, Verfahren zu ihrer Herstellung, pharmazeutische Präparate enthaltend solche Verbindungen und Verwendung von letzteren
US4409214A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical, Co., Ltd. 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
GR75644B (ru) * 1980-06-18 1984-08-02 Fujisawa Pharmaceutical Co
GR78245B (ru) * 1980-09-12 1984-09-26 Ciba Geigy Ag
US4521413A (en) * 1981-09-14 1985-06-04 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
US4486586A (en) * 1983-02-10 1984-12-04 Bristol-Myers Company Cephalosporin derivatives

Also Published As

Publication number Publication date
ES8706694A1 (es) 1987-07-01
GR850883B (ru) 1985-11-25
NZ211659A (en) 1988-11-29
RU2056425C1 (ru) 1996-03-20
IL74826A (en) 1990-01-18
SE8501680D0 (sv) 1985-04-03
JPS61143387A (ja) 1986-07-01
GB2157293B (en) 1988-10-05
AU610278B2 (en) 1991-05-16
JPS61143391A (ja) 1986-07-01
IE58408B1 (en) 1993-09-22
JPS615084A (ja) 1986-01-10
JPH0351716B2 (ru) 1991-08-07
ES8706155A1 (es) 1987-06-01
FI84830C (fi) 1992-01-27
AT388735B (de) 1989-08-25
NL192925C (nl) 1998-05-07
JPH0262557B2 (ru) 1990-12-26
JPH0357106B2 (ru) 1991-08-30
AR244694A1 (es) 1993-11-30
KR850007424A (ko) 1985-12-04
SE8901226D0 (sv) 1989-04-06
SE466205B (sv) 1992-01-13
AU4086285A (en) 1985-10-17
YU60085A (en) 1987-12-31
NL192925B (nl) 1998-01-05
ES551550A0 (es) 1987-06-01
ES551551A0 (es) 1987-07-01
CH669197A5 (de) 1989-02-28
CA1340638C (en) 1999-07-06
ES8607318A1 (es) 1986-06-16
GB2194789A (en) 1988-03-16
SE8901224L (sv) 1989-04-06
IL74826A0 (en) 1985-07-31
IT8520267A0 (it) 1985-04-05
OA07985A (fr) 1987-01-31
GB2194790A (en) 1988-03-16
SE8901225L (sv) 1989-04-06
FI84830B (fi) 1991-10-15
GB2157293A (en) 1985-10-23
SE8901224D0 (sv) 1989-04-06
HUT37622A (en) 1986-01-23
ATA103985A (de) 1989-01-15
HU204277B (en) 1991-12-30
IE58403B1 (en) 1993-09-22
GB2194790B (en) 1988-10-05
ES8800949A1 (es) 1987-12-01
DD249024A5 (de) 1987-08-26
DD236735A5 (de) 1986-06-18
SE8901226L (sv) 1989-04-06
YU118987A (en) 1988-10-31
FR2563832A1 (fr) 1985-11-08
MY101940A (en) 1992-02-15
GB8508846D0 (en) 1985-05-09
DK155985D0 (da) 1985-04-03
JPS61143390A (ja) 1986-07-01
BE902148A (fr) 1985-10-09
SE470259B (sv) 1993-12-20
HU193750B (en) 1987-11-30
FI851379L (fi) 1985-10-10
AU580990B2 (en) 1989-02-09
NL8501002A (nl) 1985-11-01
ES557060A0 (es) 1987-12-01
GB8721347D0 (en) 1987-10-14
SU1375140A3 (ru) 1988-02-15
GB8721346D0 (en) 1987-10-14
DE3512225C2 (ru) 1990-02-22
LU85840A1 (fr) 1985-12-16
KR870002166B1 (ko) 1987-12-14
YU46213B (sh) 1993-05-28
GB2194789B (en) 1988-10-12
CA1276929C (en) 1990-11-27
ZA852236B (en) 1985-11-27
DK155985A (da) 1985-10-10
SE470260B (sv) 1993-12-20
SU1367858A3 (ru) 1988-01-15
FI851379A0 (fi) 1985-04-04
PT80246B (pt) 1987-10-20
YU46151B (sh) 1993-05-28
IE850866L (en) 1985-10-09
SE8501680L (sv) 1985-10-10
AU2504188A (en) 1989-03-02
SU1436882A3 (ru) 1988-11-07
IT1190353B (it) 1988-02-16
DD251752A5 (de) 1987-11-25
SE505256C2 (sv) 1997-07-21
JPH0350754B2 (ru) 1991-08-02
ES542013A0 (es) 1986-06-16
SU1487814A3 (ru) 1989-06-15
PT80246A (en) 1985-05-01
DE3512225A1 (de) 1985-10-17
CA1340672C (en) 1999-07-20
SE8901225D0 (sv) 1989-04-06

Similar Documents

Publication Publication Date Title
FR2563832B1 (fr) Nouveaux derives cephem, procede pour la preparation de ces nouveaux composes, compositions pharmaceutiques contenant au moins un de ces composes et intermediaires de synthese pour leur preparation
FR2595351B1 (fr) Derives d'indole, procede pour leur preparation et compositions pharmaceutiques les contenant
FR2567131B1 (fr) Nouveaux derives de ganglioside, procede pour leur obtention et composition pharmaceutique les contenant
PT78340B (fr) Procede de preparation de nouveaux derives de la tetrahydroxy- 3',4',5,7-flavone et des compositions pharmaceutiques les contenant
FR2665898B1 (fr) Derives d'amido-3 pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant.
MA26620A1 (fr) Derives bicycliques d'acide hydroxamique nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant
DZ712A1 (fr) Nouveaux dérivés de 2-2 iminobisethanol utiles comme médecaments, intermédiaires pour leur préparation et procédés pour la préparation de ces dérivés et intermédiaires.
FR2568252B1 (fr) Derives de 5h-2,3-benzodiazepine, procede pour les preparer et compositions pharmaceutiques les contenant
FR2542740B1 (fr) Derives de thiazolidine, procede pour leur preparation et compositions pharmaceutiques les contenant
PT83896A (fr) Procede pour la preparation de nouveaux conjuges de la vinblas-tine et de ses derives et de compositions pharmaceutiques les contenant
FR2537141B1 (fr) Procede de preparation de composes de cephem, nouveaux produits ainsi obtenus et compositions pharmaceutiques les renfermant
FR2574793B1 (fr) Composes derives d'indole, compositions pharmaceutiques les contenant et procede pour leur preparation
MA21148A1 (fr) Procede de preparation de compose b-lactamique et intermediaires pour sa synthese .
BE892552A (fr) Nouveaux amido-aminoacides, compositions pharmaceutiques les contenant et procede de preparation de ces amido-aminoacides
FR2524890B1 (fr) Nouveaux derives de carbapenem, compositions pharmaceutiques les contenant, composes intermediaires pour leur preparation, et leurs procedes de production
FR2621587B1 (fr) Derives du dimethyl-2,2 chromene, procede pour leur preparation et composition pharmaceutiques les contenant
FR2728901B1 (fr) Derives de phenyl-4-thiazoles substitues, procede pour leur preparation et compositions pharmaceutiques les contenant
FR2557114B1 (fr) Nouveaux derives de la gonadoliberine, procede pour leur preparation et compositions pharmaceutiques les contenant
PT81992A (fr) Procede de preparation de derives de (dihydro-4,5-1h-imidazolyl-2)-2 dihydro-2,3 indole et de compositions pharmaceutiques les contenant
MA26583A1 (fr) Derives de benzamide nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant
FR2625501B1 (fr) Nouveaux derives substitues du styrene, leur procede de preparation et compositions pharmaceutiques les contenant
FR2563519B1 (fr) Derives d'iminothiazolidine, procede pour leur preparation et compositions pharmaceutiques les contenant
MA24214A1 (fr) Procede pour la preparation de nouveaux composes et pour la preparation de compositions pharmaceutiques les contenant
FR2563520B1 (fr) Nouveaux derives d'apovincaminol, procede pour leur preparation et compositions pharmaceutiques les contenant
FR2621314B1 (fr) Nouveaux derives de quinoleinium et d'isoquinoleinium, procede pour leur preparation et compositions pharmaceutiques les contenant