FI112090B - Menetelmä, plasmidi ja mikro-organismi difteriatoksiinin tai sen kanssa ristireagoivan CRM-proteiinin tuottamiseksi - Google Patents

Menetelmä, plasmidi ja mikro-organismi difteriatoksiinin tai sen kanssa ristireagoivan CRM-proteiinin tuottamiseksi Download PDF

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Publication number
FI112090B
FI112090B FI941050A FI941050A FI112090B FI 112090 B FI112090 B FI 112090B FI 941050 A FI941050 A FI 941050A FI 941050 A FI941050 A FI 941050A FI 112090 B FI112090 B FI 112090B
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Prior art keywords
plasmid
diphtheria toxin
crm197
gene
protein
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FI941050A
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English (en)
Finnish (fi)
Swedish (sv)
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FI941050A0 (fi
FI941050A (fi
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Benjamin J Metcalf
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Wyeth Corp
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)

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  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
FI941050A 1993-03-05 1994-03-04 Menetelmä, plasmidi ja mikro-organismi difteriatoksiinin tai sen kanssa ristireagoivan CRM-proteiinin tuottamiseksi FI112090B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2728393A 1993-03-05 1993-03-05
US2728393 1993-03-05

Publications (3)

Publication Number Publication Date
FI941050A0 FI941050A0 (fi) 1994-03-04
FI941050A FI941050A (fi) 1994-09-06
FI112090B true FI112090B (fi) 2003-10-31

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FI941050A FI112090B (fi) 1993-03-05 1994-03-04 Menetelmä, plasmidi ja mikro-organismi difteriatoksiinin tai sen kanssa ristireagoivan CRM-proteiinin tuottamiseksi

Country Status (21)

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US (1) US5614382A (de)
EP (1) EP0616034B1 (de)
JP (1) JP4144813B2 (de)
KR (1) KR100316004B1 (de)
CN (1) CN1100757A (de)
AT (1) ATE280235T1 (de)
AU (1) AU686126B2 (de)
BR (1) BR1100634A (de)
CA (1) CA2116914C (de)
CZ (1) CZ39394A3 (de)
DE (1) DE69434079T2 (de)
DK (1) DK0616034T3 (de)
ES (1) ES2231770T3 (de)
FI (1) FI112090B (de)
HU (1) HUT71320A (de)
IL (1) IL108822A (de)
NO (1) NO313758B1 (de)
NZ (1) NZ260027A (de)
PT (1) PT616034E (de)
SK (1) SK24094A3 (de)
ZA (1) ZA941548B (de)

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AU5759594A (en) 1994-09-08
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ATE280235T1 (de) 2004-11-15
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SK24094A3 (en) 1995-03-08
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EP0616034A2 (de) 1994-09-21
ES2231770T3 (es) 2005-05-16
PT616034E (pt) 2005-02-28
IL108822A0 (en) 1994-06-24
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CA2116914A1 (en) 1994-09-06
KR100316004B1 (ko) 2002-02-19
CN1100757A (zh) 1995-03-29
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US5614382A (en) 1997-03-25
FI941050A0 (fi) 1994-03-04
EP0616034A3 (en) 1996-10-16
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KR940021731A (ko) 1994-10-19
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