FI105476B - Uusi menetelmä 4-metyyli-5-(2-kloorietyyli)-tiatsolin ja sen analogien valmistamiseksi - Google Patents

Uusi menetelmä 4-metyyli-5-(2-kloorietyyli)-tiatsolin ja sen analogien valmistamiseksi Download PDF

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Publication number
FI105476B
FI105476B FI941996A FI941996A FI105476B FI 105476 B FI105476 B FI 105476B FI 941996 A FI941996 A FI 941996A FI 941996 A FI941996 A FI 941996A FI 105476 B FI105476 B FI 105476B
Authority
FI
Finland
Prior art keywords
general formula
chloro
process according
methyl
thiazole
Prior art date
Application number
FI941996A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI941996A0 (fi
FI941996A (fi
Inventor
Gergely Heja
Ferenc Sperber
Csaba Huszar
Attila Nemeth
Dezso Korbonits
Pal Kiss
Csaba Goenczi
Endre Palosi
Erzsebet Molnar
Ida Szvoboda
Ferenc Morasz
Laszlo Ledniczky
Erzsebet Szabo
Peter Gyori
Erzsebet Szalay
Gyoergy Mihalovics
Mihaly Sueto
Istvan Bone
Karoly Ban
Ildiko Buttkai
Arpad Kovari
Sandor Garaczy
Karoly Gyuere
Original Assignee
Astra Ab
Csaba Huszar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU3403/91A external-priority patent/HU215850B/hu
Priority claimed from HU3402/91A external-priority patent/HU215840B/hu
Priority claimed from HU913404A external-priority patent/HU207724B/hu
Priority claimed from HUP9201124A external-priority patent/HU215849B/hu
Priority claimed from HU9201125A external-priority patent/HUT66222A/hu
Application filed by Astra Ab, Csaba Huszar filed Critical Astra Ab
Publication of FI941996A0 publication Critical patent/FI941996A0/fi
Publication of FI941996A publication Critical patent/FI941996A/fi
Application granted granted Critical
Publication of FI105476B publication Critical patent/FI105476B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C331/00—Derivatives of thiocyanic acid or of isothiocyanic acid
    • C07C331/02—Thiocyanates
    • C07C331/04—Thiocyanates having sulfur atoms of thiocyanate groups bound to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
FI941996A 1991-10-30 1994-04-29 Uusi menetelmä 4-metyyli-5-(2-kloorietyyli)-tiatsolin ja sen analogien valmistamiseksi FI105476B (fi)

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
HU3403/91A HU215850B (hu) 1991-10-30 1991-10-30 Eljárás tiocianáto-keton-származékok előállítására
HU340291 1991-10-30
HU340391 1991-10-30
HU340491 1991-10-30
HU3402/91A HU215840B (hu) 1991-10-30 1991-10-30 Eljárás 2-klór-tiazol-származékok előállítására
HU913404A HU207724B (en) 1991-10-30 1991-10-30 New process for producing thiazols
HUP9201124A HU215849B (hu) 1992-04-03 1992-04-03 Eljárás 2-klór-4-metil-5-(halogén-alkil)-1,3-tiazol-származékok előállítására
HU9201125 1992-04-03
HU9201125A HUT66222A (en) 1992-04-03 1992-04-03 2-hydroxy-4-methyl-5-halogenoalkyl-1,3-thiazole derivatives and process for producing them
HU9201124 1992-04-03
HU9200042 1992-10-30
PCT/HU1992/000042 WO1993009107A1 (en) 1991-10-30 1992-10-30 Novel process for the preparation of 4-methyl-5-(2-chloroethyl)-thiazole and analogues thereof

Publications (3)

Publication Number Publication Date
FI941996A0 FI941996A0 (fi) 1994-04-29
FI941996A FI941996A (fi) 1994-04-29
FI105476B true FI105476B (fi) 2000-08-31

Family

ID=27517525

Family Applications (1)

Application Number Title Priority Date Filing Date
FI941996A FI105476B (fi) 1991-10-30 1994-04-29 Uusi menetelmä 4-metyyli-5-(2-kloorietyyli)-tiatsolin ja sen analogien valmistamiseksi

Country Status (24)

Country Link
US (2) US5648498A (ja)
EP (2) EP0619815B1 (ja)
JP (1) JP3190959B2 (ja)
KR (1) KR100218131B1 (ja)
AT (1) ATE151761T1 (ja)
AU (1) AU664868B2 (ja)
CA (1) CA2121488A1 (ja)
CZ (1) CZ283402B6 (ja)
DE (1) DE69219154T2 (ja)
DK (1) DK0619815T3 (ja)
ES (1) ES2100365T3 (ja)
FI (1) FI105476B (ja)
GR (1) GR3023842T3 (ja)
HK (1) HK93397A (ja)
HR (1) HRP921128B1 (ja)
HU (1) HU217079B (ja)
IL (1) IL103586A (ja)
IS (1) IS1688B (ja)
LV (1) LV12130B (ja)
NO (1) NO304650B1 (ja)
PL (1) PL172013B1 (ja)
SI (1) SI9200292B (ja)
SK (1) SK279665B6 (ja)
WO (1) WO1993009107A1 (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19548417A1 (de) * 1995-12-22 1997-06-26 Bayer Ag Verfahren zur Herstellung von 2-Chlor-5-chlormethylthiazol
HUP0900267A2 (en) 2009-04-30 2011-03-28 Sanofi Aventis Process for preparing of thiazole amines and intermediates thereof

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1808893A (en) * 1931-06-09 Leon c
GB456751A (en) * 1935-05-13 1936-11-13 Ig Farbenindustrie Ag Process for the manufacture of 4-alkyl-5-hydroxy-alkylthiazoles
CH200248A (de) * 1937-03-12 1938-09-30 Hoffmann La Roche Verfahren zur Darstellung von 4-Methyl-5-B-chloräthylthiazol.
US2395453A (en) * 1944-02-26 1946-02-26 Rohm & Haas Beta-thiocyano ketones and method for their preparation
FR1274353A (fr) * 1955-09-28 1961-10-27 Procédé de préparation des méthyl-4 bêta-halogénoéthyl-5 thiazoles et de leurs sels
DE1082903B (de) * 1957-10-11 1960-06-09 Basf Ag Verfahren zur Herstellung von Rhodanverbindungen
DE1515197C3 (de) * 1964-05-06 1974-08-15 Steigerwald Strahltechnik Gmbh, 8000 Muenchen Energiestrahl-Schweiß verfahren
BE668231A (ja) * 1964-08-12
US3670004A (en) * 1969-01-07 1972-06-13 Buckman Labor Inc Thiocyano substituted acrylates and propionates and their use as pesticides
FR2152345A1 (en) * 1971-09-06 1973-04-27 Roussel Uclaf Alpha-(2-thiazolyl)oxyalkanoic acids and derivatives - - with analgesic,antiinflammatory and antipyretic activity
DE2236796A1 (de) * 1972-07-27 1974-02-07 Georg Dipl Chem Dr Herbertz 2-hydroxy-4-methyl-5-(2-chloraethyl)thiazol
DE2423981A1 (de) * 1974-05-17 1975-11-27 Bayer Ag Alpha - halogenketone
DE2339109A1 (de) * 1973-08-02 1975-02-20 Bayer Ag Alpha-halogenketone
DE2823658A1 (de) * 1978-05-30 1979-12-06 Bayer Ag Mittel zur bekaempfung von pflanzenbakteriosen
US4284426A (en) * 1979-10-01 1981-08-18 Monsanto Company 2-Chloro-4,5-disubstituted-thiazoles useful as herbicidal safeners
US4377693A (en) * 1979-10-01 1983-03-22 Monsanto Company 2-Chloro-4,5-disubstituted-thiazoles useful as herbicidal safeners
US4284784A (en) * 1980-05-22 1981-08-18 Merck & Co., Inc. Process for the preparation of 4-methyl thiazole
SU943233A1 (ru) * 1980-07-18 1982-07-15 Ереванский государственный университет @ -Роданвинилметилкетон в качестве мономера дл синтеза ионитов и полиэлектролитов и способ его получени
GB8705447D0 (en) * 1987-03-09 1987-04-15 Autopia Terakat Accessories Lt Glass frail
US4822813A (en) * 1987-03-11 1989-04-18 Uniroyal Chemical Ltd./Uniroyal Chemical Ltee 3-(2-Haloalkyl)-1,4-oxathiins and 2-(2-haloalkyl)-1,4-dithiins, and treatment of leukemia and tumors therewith
SE8900564D0 (sv) * 1989-02-17 1989-02-17 Astra Ab Novel medicinal use
US5180833A (en) * 1990-03-16 1993-01-19 Takeda Chemical Industries, Ltd. Process for the preparation of chlorothiazole derivatives
HU206198B (en) * 1990-09-21 1992-09-28 Egyt Gyogyszervegyeszeti Gyar Process for producing rhodanidoisobutyric acid

Also Published As

Publication number Publication date
HRP921128B1 (en) 1998-10-31
SK50194A3 (en) 1995-02-08
HRP921128A2 (en) 1995-10-31
SI9200292B (sl) 1999-06-30
NO304650B1 (no) 1999-01-25
HUT70739A (en) 1995-10-30
SK279665B6 (sk) 1999-02-11
IL103586A (en) 1997-09-30
CZ283402B6 (cs) 1998-04-15
EP0546306A1 (en) 1993-06-16
AU664868B2 (en) 1995-12-07
ATE151761T1 (de) 1997-05-15
IS1688B (is) 1998-04-20
JP3190959B2 (ja) 2001-07-23
HU9401262D0 (en) 1994-08-29
IL103586A0 (en) 1993-03-15
SI9200292A (en) 1993-06-30
DE69219154T2 (de) 1997-07-24
CZ103494A3 (en) 1995-11-15
EP0619815B1 (en) 1997-04-16
EP0546306B1 (en) 1997-04-16
CA2121488A1 (en) 1993-05-13
US5648498A (en) 1997-07-15
JPH07503233A (ja) 1995-04-06
PL172013B1 (pl) 1997-07-31
NO941567L (ja) 1994-06-22
IS3937A (is) 1993-05-01
GR3023842T3 (en) 1997-09-30
DE69219154D1 (de) 1997-05-22
HK93397A (en) 1997-08-01
WO1993009107A1 (en) 1993-05-13
LV12130B (en) 1999-02-20
KR100218131B1 (ko) 1999-09-01
NO941567D0 (ja) 1994-04-28
ES2100365T3 (es) 1997-06-16
FI941996A0 (fi) 1994-04-29
DK0619815T3 (da) 1997-09-01
LV12130A (lv) 1998-09-20
US5534644A (en) 1996-07-09
AU2912392A (en) 1993-06-07
HU217079B (hu) 1999-11-29
FI941996A (fi) 1994-04-29
EP0619815A1 (en) 1994-10-19

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