|
EP2858722B8
(en)
|
2012-06-08 |
2018-02-21 |
Aduro BioTech, Inc. |
Compostions and methods for cancer immunotherapy
|
|
US9695212B2
(en)
|
2012-12-13 |
2017-07-04 |
Aduro Biotech, Inc. |
Compositions comprising cyclic purine dinucleotides having defined stereochemistries and methods for their preparation and use
|
|
EP2934598B1
(en)
|
2012-12-19 |
2018-04-18 |
Board Of Regents, The University Of Texas System |
Pharmaceutical targeting of a mammalian cyclic di-nucleotide signaling pathway
|
|
US9840533B2
(en)
|
2013-04-29 |
2017-12-12 |
Memorial Sloan Kettering Cancer Center |
Compositions and methods for altering second messenger signaling
|
|
WO2014179760A1
(en)
|
2013-05-03 |
2014-11-06 |
The Regents Of The University Of California |
Cyclic di-nucleotide induction of type i interferon
|
|
PE20160080A1
(es)
*
|
2013-05-18 |
2016-02-21 |
Aduro Biotech Inc |
Composiciones y metodos para activar la senalizacion que depende del estimulador del gen de interferon
|
|
US9549944B2
(en)
|
2013-05-18 |
2017-01-24 |
Aduro Biotech, Inc. |
Compositions and methods for inhibiting “stimulator of interferon gene”—dependent signalling
|
|
US10176292B2
(en)
|
2013-07-31 |
2019-01-08 |
Memorial Sloan-Kettering Cancer Center |
STING crystals and modulators
|
|
CR20160564A
(es)
|
2014-06-04 |
2017-01-20 |
Glaxosmithkline Ip Dev Ltd |
Dinucleótidos cíclicos como moduladores de sting
|
|
WO2016096577A1
(en)
*
|
2014-12-16 |
2016-06-23 |
Invivogen |
Combined use of a chemotherapeutic agent and a cyclic dinucleotide for cancer treatment
|
|
EP3546473B1
(en)
|
2014-12-16 |
2025-12-10 |
Kayla Therapeutics |
Fluorinated cyclic [(2',5')p(3',5')p]-dinucleotides for cytokine induction
|
|
US20180344758A1
(en)
*
|
2014-12-17 |
2018-12-06 |
Lipogen Llc |
Method of Treating Cancer with cGAMP or cGAsMP
|
|
GB201501462D0
(en)
|
2015-01-29 |
2015-03-18 |
Glaxosmithkline Ip Dev Ltd |
Novel compounds
|
|
EA035817B1
(ru)
|
2015-03-10 |
2020-08-14 |
Адуро Байотек, Инк. |
Композиции и способы для активации сигналинга, зависимого от "гена стимулятора интерферона"
|
|
CN106692967A
(zh)
*
|
2015-08-12 |
2017-05-24 |
聊城市奥润生物医药科技有限公司 |
环二核苷酸cGAMP联合PD1的抗体(Nivolumab)在制备抗肿瘤药物中的应用
|
|
KR102222186B1
(ko)
|
2015-08-13 |
2021-03-03 |
머크 샤프 앤드 돔 코포레이션 |
Sting 효능제로서 시클릭 디-뉴클레오티드 화합물
|
|
US11453697B1
(en)
|
2015-08-13 |
2022-09-27 |
Merck Sharp & Dohme Llc |
Cyclic di-nucleotide compounds as sting agonists
|
|
US9809597B2
(en)
|
2015-08-20 |
2017-11-07 |
The Board Of Trustees Of The Leland Stanford Junior University |
Ganciclovir derivatives for modulating innate and adaptive immunity and for use in immunotherapy
|
|
CN106540255A
(zh)
*
|
2015-09-18 |
2017-03-29 |
聊城市奥润生物医药科技有限公司 |
环二核苷酸cGAMP联合贝伐珠单抗在抗肿瘤中的应用
|
|
US10322177B2
(en)
|
2015-10-07 |
2019-06-18 |
Nant Holdings Ip, Llc |
Activation of immune-related signaling pathways in cells via optofection
|
|
JP2018534295A
(ja)
|
2015-10-28 |
2018-11-22 |
アドゥロ バイオテック,インク. |
「インターフェロン遺伝子刺激因子」依存性シグナル伝達を活性化するための組成物および方法
|
|
CN106539812B
(zh)
*
|
2015-11-18 |
2019-12-03 |
杭州星鳌生物科技有限公司 |
环二核苷酸cGAMP在抗结直肠癌肝转移中的应用
|
|
CN106539813B
(zh)
*
|
2015-11-30 |
2019-12-03 |
杭州星鳌生物科技有限公司 |
干扰素刺激基因(sting)激活剂在抗炎症中的应用
|
|
CN107849084B
(zh)
|
2015-12-03 |
2021-09-14 |
葛兰素史密斯克莱知识产权发展有限公司 |
作为sting调节剂的环状嘌呤二核苷酸
|
|
CN106540260A
(zh)
*
|
2015-12-09 |
2017-03-29 |
聊城市奥润生物医药科技有限公司 |
干扰素基因刺激蛋白(sting)激动剂在抗阿尔兹海默症中的应用
|
|
CN106539814A
(zh)
*
|
2015-12-09 |
2017-03-29 |
聊城市奥润生物医药科技有限公司 |
干扰素基因刺激蛋白(sting)激动剂在抗类风湿性关节炎等疾病中的应用
|
|
US20180369268A1
(en)
*
|
2015-12-16 |
2018-12-27 |
Aduro Biotech, Inc. |
Methods for identifying inhibitors of "stimulator of interferon gene"- dependent interferon production
|
|
CN106539811B
(zh)
*
|
2016-01-16 |
2019-12-20 |
杭州星鳌生物科技有限公司 |
环二核苷酸cGAMP在防治抗肿瘤化药诱发的并发症或降低化疗药诱导的毒副作用中的应用
|
|
CN106539815B
(zh)
*
|
2016-01-21 |
2019-12-03 |
杭州星鳌生物科技有限公司 |
环二核苷酸在防治多发性硬化症中的应用
|
|
NZ746112A
(en)
*
|
2016-03-18 |
2023-01-27 |
Immune Sensor Llc |
Cyclic di-nucleotide compounds and methods of use
|
|
CN106539757A
(zh)
*
|
2016-03-20 |
2017-03-29 |
聊城市奥润生物医药科技有限公司 |
环二核苷酸cGAMP-脂质体在抗肿瘤中的应用
|
|
CN106540256A
(zh)
*
|
2016-03-27 |
2017-03-29 |
聊城市奥润生物医药科技有限公司 |
环二核苷酸-脂质体偶联单克隆抗体在抗肿瘤中的应用
|
|
CN105969754A
(zh)
*
|
2016-04-29 |
2016-09-28 |
山东省农业科学院畜牧兽医研究所 |
改造的核苷酸环化酶及其应用
|
|
US10696985B1
(en)
|
2016-06-06 |
2020-06-30 |
Vanderbilt University |
Reversibly crosslinked endosomolytic polymer vesicles for cytosolic drug delivery
|
|
CN106552265A
(zh)
*
|
2016-06-21 |
2017-04-05 |
聊城市奥润生物医药科技有限公司 |
Sting激动剂与ido1抑制剂联合用药在抗肿瘤中的应用
|
|
EP3507367A4
(en)
|
2016-07-05 |
2020-03-25 |
Aduro BioTech, Inc. |
CYCLIC DINUCLEOTID COMPOUNDS WITH INCLUDED NUCLEIC ACIDS AND USES THEREOF
|
|
IL264049B2
(en)
|
2016-07-06 |
2023-11-01 |
Sperovie Biosciences Inc |
Compounds, preparations and methods for treating the disease
|
|
WO2018009652A1
(en)
*
|
2016-07-06 |
2018-01-11 |
Sperovie Biosciences, Inc. |
Compounds, compositions, and methods for the treatment of disease
|
|
NL2017270B1
(en)
|
2016-08-02 |
2018-02-09 |
Aduro Biotech Holdings Europe B V |
New anti-hCTLA-4 antibodies
|
|
AU2017321609C1
(en)
|
2016-08-30 |
2023-11-09 |
Dana-Farber Cancer Institute, Inc. |
Drug delivery compositions and uses thereof
|
|
EA037513B1
(ru)
*
|
2016-09-17 |
2021-04-06 |
ИММЬЮН СЕНСОР, ЭлЭлСи |
Циклические динуклеотидные соединения и способы их применения
|
|
US10537590B2
(en)
|
2016-09-30 |
2020-01-21 |
Boehringer Ingelheim International Gmbh |
Cyclic dinucleotide compounds
|
|
PT3523287T
(pt)
|
2016-10-04 |
2021-10-06 |
Merck Sharp & Dohme |
Compostos de benzo[b]tiofeno como agonistas de sting
|
|
US11001605B2
(en)
|
2016-10-07 |
2021-05-11 |
Biolog Life Science Institute Gmbh & Co. Kg |
Cyclic dinucleotides containing benzimidazole, method for the production of same, and use of same to activate stimulator of interferon genes (sting)-dependent signaling pathways
|
|
KR20230010826A
(ko)
|
2016-10-14 |
2023-01-19 |
프리시젼 바이오사이언시스 인코포레이티드 |
B형 간염 바이러스 게놈 내의 인식 서열에 대해 특이적인 조작된 메가뉴클레아제
|
|
PE20210255A1
(es)
|
2016-12-01 |
2021-02-10 |
Takeda Pharmaceuticals Co |
Dinucleotido ciclico como agonistas de sting (estimulador de genes de interferon)
|
|
EP3558319A4
(en)
*
|
2016-12-22 |
2020-07-22 |
AbbVie Inc. |
COMPOSITIONS AND PROCESSES FOR IMPROVING OR INCREASING THE PRODUCTION OF TYPE I IFN
|
|
EA201991556A1
(ru)
*
|
2016-12-22 |
2020-01-23 |
Мавуфарма, Инк. |
Ингибиторы фосфодиэстеразы и способы лечения микробной инфекции
|
|
CN110234403A
(zh)
*
|
2017-01-27 |
2019-09-13 |
詹森生物科技公司 |
作为sting激动剂的环状二核苷酸
|
|
BR112019015797A2
(pt)
|
2017-02-01 |
2020-03-17 |
Modernatx, Inc. |
Composições de mrna terapêuticas imunomoduladoras que codificam peptídeos de mutação de oncogene de ativação
|
|
JP2018131427A
(ja)
*
|
2017-02-17 |
2018-08-23 |
国立研究開発法人理化学研究所 |
免疫細胞の制御技術
|
|
US20200055883A1
(en)
|
2017-02-17 |
2020-02-20 |
Eisai R&D Management Co., Ltd. |
Cyclic di-nucleotides derivative for the treatment of cancer
|
|
CN106727331B
(zh)
*
|
2017-03-13 |
2022-02-01 |
杭州星鳌生物科技有限公司 |
免疫脂质体-环二核苷酸的组成、制备方法及其在抗肿瘤中的应用
|
|
CN106667914B
(zh)
*
|
2017-03-13 |
2022-02-01 |
杭州星鳌生物科技有限公司 |
靶向脂质体-环二核苷酸的组成、制备方法及其在抗肿瘤中的应用
|
|
US10859566B2
(en)
|
2017-03-20 |
2020-12-08 |
Genocea Biosciences, Inc. |
Treatment methods
|
|
JOP20190218A1
(ar)
|
2017-03-22 |
2019-09-22 |
Boehringer Ingelheim Int |
مركبات ثنائية النيوكليوتيدات حلقية معدلة
|
|
KR102702926B1
(ko)
|
2017-04-13 |
2024-09-06 |
사이로파 비.브이. |
항-sirp 알파 항체
|
|
MX2019012295A
(es)
|
2017-04-14 |
2020-02-07 |
Tollnine Inc |
Polinucleotidos inmunomoduladores, conjugados de anticuerpos de los mismos y metodos para su uso.
|
|
US11466047B2
(en)
|
2017-05-12 |
2022-10-11 |
Merck Sharp & Dohme Llc |
Cyclic di-nucleotide compounds as sting agonists
|
|
RU2020109328A
(ru)
|
2017-08-04 |
2021-09-06 |
Мерк Шарп И Доум Корп. |
Комбинации антагонистов pd-1 и бензо[b]тиофеновых агонистов sting для лечения рака
|
|
JP2020530838A
(ja)
|
2017-08-04 |
2020-10-29 |
メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. |
がん治療のためのベンゾ[b]チオフェンSTINGアゴニスト
|
|
KR20240151869A
(ko)
|
2017-09-08 |
2024-10-18 |
더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 |
Enpp1 저해제 및 암의 치료용의 이의 용도
|
|
US11707531B2
(en)
|
2017-09-11 |
2023-07-25 |
F-star Therapeutics, Inc. |
Compounds, compositions, and methods for the treatment of disease
|
|
US11584774B2
(en)
|
2017-09-11 |
2023-02-21 |
F-star Therapeutics, Inc. |
Compounds, compositions, and methods for the treatment of disease
|
|
CN107619438B
(zh)
*
|
2017-10-11 |
2021-12-03 |
广州云启科技有限公司 |
新型环二核苷酸受体及其激动剂或抑制剂筛选的方法和试剂盒
|
|
CN109694397B
(zh)
*
|
2017-10-23 |
2021-08-31 |
上海弘翊生物科技有限公司 |
环状二核苷酸化合物、其制备方法和应用
|
|
KR20200098511A
(ko)
|
2017-11-10 |
2020-08-20 |
다케다 야쿠힌 고교 가부시키가이샤 |
Sting 조절제 화합물, 및 제조 및 사용 방법
|
|
WO2019123339A1
(en)
|
2017-12-20 |
2019-06-27 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
2'3' cyclic dinucleotides with phosphonate bond activating the sting adaptor protein
|
|
EP3728283B1
(en)
|
2017-12-20 |
2023-11-22 |
Institute of Organic Chemistry and Biochemistry ASCR, V.V.I. |
3'3' cyclic dinucleotides with phosphonate bond activating the sting adaptor protein
|
|
EP3727401A4
(en)
|
2017-12-20 |
2022-04-06 |
Merck Sharp & Dohme Corp. |
CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS
|
|
EP3743103A4
(en)
*
|
2018-01-26 |
2021-03-17 |
The Regents of The University of California |
INTRANASAL ADMINISTRATION OF CYCLIC DI-NUCLEOTIDE ADJUVED VACCINE FOR TUBERCULOSIS
|
|
WO2019161171A1
(en)
*
|
2018-02-16 |
2019-08-22 |
Sperovie Biosciences, Inc. |
Nanoparticle formulations of sting agonists
|
|
JP7050165B2
(ja)
|
2018-02-26 |
2022-04-07 |
ギリアード サイエンシーズ, インコーポレイテッド |
Hbv複製阻害剤としての置換ピロリジン化合物
|
|
CA3093849A1
(en)
|
2018-03-23 |
2019-09-26 |
Codiak Biosciences, Inc. |
Extracellular vesicles comprising sting-agonist
|
|
CA3097850A1
(en)
*
|
2018-03-26 |
2019-10-03 |
University Of Miami |
Recombinant viral vector and uses thereof
|
|
WO2019185477A1
(en)
|
2018-03-27 |
2019-10-03 |
Boehringer Ingelheim International Gmbh |
Cyclic dinucleotide compounds containing 2-aza-hypoxanthine or 6h-pytazolo[1,5-d][1,2,4]triazin-7-one as sting agonists
|
|
JP2021519279A
(ja)
|
2018-03-27 |
2021-08-10 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
修飾環式ジヌクレオチド化合物
|
|
EP3774765A4
(en)
|
2018-04-03 |
2021-12-29 |
Merck Sharp & Dohme Corp. |
Aza-benzothiophene compounds as sting agonists
|
|
JP7326319B2
(ja)
|
2018-04-03 |
2023-08-15 |
メルク・シャープ・アンド・ドーム・エルエルシー |
Stingアゴニストとしてのベンゾチオフェン類及び関連する化合物
|
|
US10870691B2
(en)
|
2018-04-05 |
2020-12-22 |
Gilead Sciences, Inc. |
Antibodies and fragments thereof that bind hepatitis B virus protein X
|
|
WO2019195658A1
(en)
|
2018-04-05 |
2019-10-10 |
Dana-Farber Cancer Institute, Inc. |
Sting levels as a biomarker for cancer immunotherapy
|
|
TWI833744B
(zh)
|
2018-04-06 |
2024-03-01 |
捷克科學院有機化學與生物化學研究所 |
3'3'-環二核苷酸
|
|
TWI818007B
(zh)
*
|
2018-04-06 |
2023-10-11 |
捷克科學院有機化學與生物化學研究所 |
2'3'-環二核苷酸
|
|
TW202005654A
(zh)
|
2018-04-06 |
2020-02-01 |
捷克科學院有機化學與生物化學研究所 |
2,2,─環二核苷酸
|
|
US11142750B2
(en)
|
2018-04-12 |
2021-10-12 |
Precision Biosciences, Inc. |
Optimized engineered meganucleases having specificity for a recognition sequence in the Hepatitis B virus genome
|
|
CN108310378A
(zh)
*
|
2018-04-28 |
2018-07-24 |
杭州星鳌生物科技有限公司 |
一类新型免疫联体抗肿瘤创新药物的制备及其应用
|
|
US20190359645A1
(en)
|
2018-05-03 |
2019-11-28 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
2'3'-cyclic dinucleotides comprising carbocyclic nucleotide
|
|
WO2019222500A1
(en)
*
|
2018-05-17 |
2019-11-21 |
The Regents Of The University Of California |
Methods of modulating activity of a cyclic dinucleotide (cdn) with a cdn transporter-modulating agent
|
|
BR112020024605A2
(pt)
|
2018-06-01 |
2021-04-06 |
Eisai R&D Management Co., Ltd. |
Métodos para o tratamento de câncer de bexiga
|
|
US12146168B2
(en)
|
2018-06-29 |
2024-11-19 |
President And Fellows Of Harvard College |
Human CGAS-DNA complex and encoded protein
|
|
WO2020014127A1
(en)
|
2018-07-10 |
2020-01-16 |
Sperovie Biosciences, Inc. |
Compounds, compositions, and methods for the treatment of disease
|
|
WO2020028097A1
(en)
|
2018-08-01 |
2020-02-06 |
Gilead Sciences, Inc. |
Solid forms of (r)-11-(methoxymethyl)-12-(3-methoxypropoxy)-3,3-dimethyl-8-0x0-2,3,8,13b-tetrahydro-1h-pyrido[2,1-a]pyrrolo[1,2-c] phthalazine-7-c arboxylic acid
|
|
US11691990B2
(en)
|
2018-08-16 |
2023-07-04 |
Eisai R&D Management Co., Ltd |
Salts of compounds and crystals thereof
|
|
EP3841112A1
(en)
|
2018-08-24 |
2021-06-30 |
Codiak BioSciences, Inc. |
Extracellular vesicles targeting dendritic cells and uses thereof
|
|
CN110938104B
(zh)
|
2018-09-21 |
2024-07-12 |
上海迪诺医药科技有限公司 |
环状二核苷酸类似物、其药物组合物及应用
|
|
WO2020092379A1
(en)
|
2018-10-29 |
2020-05-07 |
Genocea Biosciences, Inc. |
Treatment methods
|
|
US12508233B2
(en)
|
2018-10-30 |
2025-12-30 |
Vanderbilt University |
Graft copolymers, methods of forming graft copolymers, and methods of use thereof
|
|
WO2020092528A1
(en)
|
2018-10-31 |
2020-05-07 |
Gilead Sciences, Inc. |
Substituted 6-azabenzimidazole compounds having hpk1 inhibitory activity
|
|
US11203591B2
(en)
|
2018-10-31 |
2021-12-21 |
Gilead Sciences, Inc. |
Substituted 6-azabenzimidazole compounds
|
|
US20220136023A1
(en)
*
|
2019-03-01 |
2022-05-05 |
Yamasa Corporation |
Practical enzymatic synthesis of 3',3'-cgamp
|
|
WO2020178770A1
(en)
|
2019-03-07 |
2020-09-10 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
3'3'-cyclic dinucleotides and prodrugs thereof
|
|
WO2020178768A1
(en)
|
2019-03-07 |
2020-09-10 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
3'3'-cyclic dinucleotide analogue comprising a cyclopentanyl modified nucleotide as sting modulator
|
|
EP3934757B1
(en)
|
2019-03-07 |
2023-02-22 |
Institute of Organic Chemistry and Biochemistry ASCR, V.V.I. |
2'3'-cyclic dinucleotides and prodrugs thereof
|
|
US20240108747A1
(en)
|
2019-03-21 |
2024-04-04 |
Lonza Sales Ag |
Extracellular vesicle conjugates and uses thereof
|
|
BR112021018694A2
(pt)
|
2019-03-21 |
2021-11-30 |
Codiak Biosciences Inc |
Vesículas extracelulares para distribuição de vacina
|
|
TW202212339A
(zh)
|
2019-04-17 |
2022-04-01 |
美商基利科學股份有限公司 |
類鐸受體調節劑之固體形式
|
|
TWI751516B
(zh)
|
2019-04-17 |
2022-01-01 |
美商基利科學股份有限公司 |
類鐸受體調節劑之固體形式
|
|
WO2020227421A1
(en)
|
2019-05-09 |
2020-11-12 |
Aligos Therapeutics, Inc. |
Modified cyclic dinucleoside compounds as sting modulators
|
|
EP3972695A1
(en)
|
2019-05-23 |
2022-03-30 |
Gilead Sciences, Inc. |
Substituted exo-methylene-oxindoles which are hpk1/map4k1 inhibitors
|
|
WO2020263830A1
(en)
|
2019-06-25 |
2020-12-30 |
Gilead Sciences, Inc. |
Flt3l-fc fusion proteins and methods of use
|
|
EP3994158A1
(en)
|
2019-07-03 |
2022-05-11 |
Codiak BioSciences, Inc. |
Extracellular vesicles targeting t cells and uses thereof
|
|
WO2021034804A1
(en)
|
2019-08-19 |
2021-02-25 |
Gilead Sciences, Inc. |
Pharmaceutical formulations of tenofovir alafenamide
|
|
US20220305048A1
(en)
|
2019-08-26 |
2022-09-29 |
Dana-Farber Cancer Institute, Inc. |
Use of heparin to promote type 1 interferon signaling
|
|
EP3785719A1
(en)
*
|
2019-08-28 |
2021-03-03 |
Helmholtz-Zentrum für Infektionsforschung GmbH |
New use of cyclic dinucleotides
|
|
MX2022003570A
(es)
|
2019-09-25 |
2022-07-11 |
Codiak Biosciences Inc |
Composiciones de vesícula extracelular.
|
|
KR20220094221A
(ko)
|
2019-09-25 |
2022-07-05 |
코디악 바이오사이언시즈, 인크. |
종양의 치료를 위한 il-12 디스플레잉 엑소좀과 조합된 sting 효능제 포함 엑소좀
|
|
WO2021062058A1
(en)
|
2019-09-25 |
2021-04-01 |
Codiak Biosciences, Inc. |
Sting agonist comprising exosomes for treating neuroimmunological disorders
|
|
WO2021062290A1
(en)
|
2019-09-25 |
2021-04-01 |
Codiak Biosciences, Inc. |
Methods of producing extracellular vesicles
|
|
DK4037708T3
(da)
|
2019-09-30 |
2024-09-30 |
Gilead Sciences Inc |
HBV-vacciner og fremgangsmåder til at behandle HBV
|
|
WO2021071823A1
(en)
*
|
2019-10-07 |
2021-04-15 |
The General Hospital Corporation |
Compositions and methods for pulmonary surfactant-biomimetic nanoparticles
|
|
DK4069729T3
(da)
|
2019-12-06 |
2025-04-07 |
Prec Biosciences Inc |
Optimerede, modificerede meganukleaser med specificitet for en genkendelsessekvens i hepatitis b-virusgenomet
|
|
CA3169523A1
(en)
|
2020-02-28 |
2021-09-02 |
Jaume Pons |
Transglutaminase-mediated conjugation
|
|
US20230114434A1
(en)
|
2020-03-13 |
2023-04-13 |
Codiak Biosciences, Inc. |
Extracellular vesicles for treating neurological disorders
|
|
JP2023518414A
(ja)
|
2020-03-20 |
2023-05-01 |
コディアック バイオサイエンシーズ, インコーポレイテッド |
治療のための細胞外小胞
|
|
WO2021188959A1
(en)
|
2020-03-20 |
2021-09-23 |
Gilead Sciences, Inc. |
Prodrugs of 4'-c-substituted-2-halo-2'-deoxyadenosine nucleosides and methods of making and using the same
|
|
WO2021237100A1
(en)
|
2020-05-21 |
2021-11-25 |
Codiak Biosciences, Inc. |
Methods of targeting extracellular vesicles to lung
|
|
EP4192474B1
(en)
|
2020-08-07 |
2025-09-10 |
Gilead Sciences, Inc. |
Prodrugs of phosphonamide nucleotide analogues and their pharmaceutical use
|
|
AU2021340623A1
(en)
|
2020-09-08 |
2023-04-13 |
The Board Of Regents Of The University Of Texas System |
Polyvalent STING activating compositions and uses thereof
|
|
US20240082389A1
(en)
|
2020-09-23 |
2024-03-14 |
Lonza Sales Ag |
Methods of producing extracellular vesicles
|
|
WO2022066883A1
(en)
|
2020-09-23 |
2022-03-31 |
Codiak Biosciences, Inc. |
Extracellular vesicles comprising kras antigens and uses thereof
|
|
IL302390A
(en)
|
2020-11-09 |
2023-06-01 |
Takeda Pharmaceuticals Co |
Drug antibody conjugates
|
|
US20240076666A1
(en)
*
|
2021-02-12 |
2024-03-07 |
The Regents Of The University Of California |
Immunomodulators Targeting MORC3 for Interferon Induction
|
|
WO2022241134A1
(en)
|
2021-05-13 |
2022-11-17 |
Gilead Sciences, Inc. |
COMBINATION OF A TLR8 MODULATING COMPOUND AND ANTI-HBV siRNA THERAPEUTICS
|
|
WO2022245671A1
(en)
|
2021-05-18 |
2022-11-24 |
Gilead Sciences, Inc. |
Methods of using flt3l-fc fusion proteins
|
|
US12208150B2
(en)
*
|
2021-05-20 |
2025-01-28 |
Shielded, Beauty, LLC |
Antimicrobial skincare composition
|
|
CN113265435A
(zh)
*
|
2021-06-16 |
2021-08-17 |
中国农业科学院兰州兽医研究所 |
一种细菌第二信使分子环二核苷酸的制备方法
|
|
MX2023014762A
(es)
|
2021-06-23 |
2024-01-15 |
Gilead Sciences Inc |
Compuestos moduladores de diacilglicerol quinasa.
|
|
JP7686091B2
(ja)
|
2021-06-23 |
2025-05-30 |
ギリアード サイエンシーズ, インコーポレイテッド |
ジアシルグリセロールキナーゼ調節化合物
|
|
AU2022299051B2
(en)
|
2021-06-23 |
2025-03-13 |
Gilead Sciences, Inc. |
Diacylglyercol kinase modulating compounds
|
|
JP7651018B2
(ja)
|
2021-06-23 |
2025-03-25 |
ギリアード サイエンシーズ, インコーポレイテッド |
ジアシルグリセロールキナーゼ調節化合物
|
|
WO2023056468A1
(en)
|
2021-09-30 |
2023-04-06 |
Codiak Biosciences, Inc. |
Extracellular vesicle comprising cholesterol tagged sting-agonist
|
|
US20260034159A1
(en)
*
|
2022-08-10 |
2026-02-05 |
Aldevron, Llc |
Methods for producing cyclic dinucleotides
|
|
CN117224686A
(zh)
*
|
2023-10-12 |
2023-12-15 |
上海市肺科医院(上海市职业病防治院) |
Tak1抑制剂在制备治疗sting相关的自身免疫性疾病的药物中的应用
|
|
WO2025240242A1
(en)
|
2024-05-13 |
2025-11-20 |
Gilead Sciences, Inc. |
Combination therapies with ribavirin
|
|
WO2025240246A1
(en)
|
2024-05-13 |
2025-11-20 |
Gilead Sciences, Inc. |
Combination therapies with ribavirin
|
|
WO2025240244A1
(en)
|
2024-05-13 |
2025-11-20 |
Gilead Sciences, Inc. |
Combination therapies comprising bulevirtide and lonafarnib for use in the treatment of hepatitis d virus infection
|
|
WO2025240243A1
(en)
|
2024-05-13 |
2025-11-20 |
Gilead Sciences, Inc. |
Combination therapies with bulevirtide and an inhibitory nucleic acid targeting hepatitis b virus
|
|
WO2026027944A1
(en)
|
2024-07-30 |
2026-02-05 |
Sairopa B.V. |
Anti-sirp alpha antibody formulations and uses thereof
|