ES2529254T3 - Proceso de fermentación usando velocidades de incorporación de oxígeno específicas como un control del proceso - Google Patents
Proceso de fermentación usando velocidades de incorporación de oxígeno específicas como un control del proceso Download PDFInfo
- Publication number
- ES2529254T3 ES2529254T3 ES03756237.8T ES03756237T ES2529254T3 ES 2529254 T3 ES2529254 T3 ES 2529254T3 ES 03756237 T ES03756237 T ES 03756237T ES 2529254 T3 ES2529254 T3 ES 2529254T3
- Authority
- ES
- Spain
- Prior art keywords
- lactic acid
- specific oxygen
- incorporation rates
- oxygen incorporation
- fermentation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000855 fermentation Methods 0.000 title abstract description 5
- 230000004151 fermentation Effects 0.000 title abstract description 5
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 title abstract description 4
- 229910052760 oxygen Inorganic materials 0.000 title abstract description 4
- 239000001301 oxygen Substances 0.000 title abstract description 4
- 238000010348 incorporation Methods 0.000 title 1
- 238000004886 process control Methods 0.000 title 1
- 238000000034 method Methods 0.000 abstract description 4
- 244000005700 microbiome Species 0.000 abstract 1
- 230000037361 pathway Effects 0.000 abstract 1
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 20
- 235000014655 lactic acid Nutrition 0.000 description 10
- 239000004310 lactic acid Substances 0.000 description 10
- 238000004519 manufacturing process Methods 0.000 description 9
- 210000004027 cell Anatomy 0.000 description 8
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 6
- JJTUDXZGHPGLLC-UHFFFAOYSA-N lactide Chemical compound CC1OC(=O)C(C)OC1=O JJTUDXZGHPGLLC-UHFFFAOYSA-N 0.000 description 5
- 229920000747 poly(lactic acid) Polymers 0.000 description 5
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 4
- 239000008103 glucose Substances 0.000 description 4
- 230000003698 anagen phase Effects 0.000 description 3
- 229920000642 polymer Polymers 0.000 description 3
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 2
- 229930182843 D-Lactic acid Natural products 0.000 description 2
- JVTAAEKCZFNVCJ-UWTATZPHSA-N D-lactic acid Chemical compound C[C@@H](O)C(O)=O JVTAAEKCZFNVCJ-UWTATZPHSA-N 0.000 description 2
- JVTAAEKCZFNVCJ-REOHCLBHSA-N L-lactic acid Chemical compound C[C@H](O)C(O)=O JVTAAEKCZFNVCJ-REOHCLBHSA-N 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 description 2
- 101150034686 PDC gene Proteins 0.000 description 2
- 238000005273 aeration Methods 0.000 description 2
- 229940022769 d- lactic acid Drugs 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- JJTUDXZGHPGLLC-IMJSIDKUSA-N 4511-42-6 Chemical compound C[C@@H]1OC(=O)[C@H](C)OC1=O JJTUDXZGHPGLLC-IMJSIDKUSA-N 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 108010001539 D-lactate dehydrogenase Proteins 0.000 description 1
- 108700007698 Genetic Terminator Regions Proteins 0.000 description 1
- 240000002605 Lactobacillus helveticus Species 0.000 description 1
- 239000001888 Peptone Substances 0.000 description 1
- 108010080698 Peptones Proteins 0.000 description 1
- 244000253911 Saccharomyces fragilis Species 0.000 description 1
- 230000005587 bubbling Effects 0.000 description 1
- 229910000019 calcium carbonate Inorganic materials 0.000 description 1
- 235000010216 calcium carbonate Nutrition 0.000 description 1
- 229940041514 candida albicans extract Drugs 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- -1 cyclic anhydride Chemical class 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000002290 gas chromatography-mass spectrometry Methods 0.000 description 1
- 230000012010 growth Effects 0.000 description 1
- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 238000011081 inoculation Methods 0.000 description 1
- 238000004949 mass spectrometry Methods 0.000 description 1
- 239000000178 monomer Substances 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 235000019319 peptone Nutrition 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 210000005253 yeast cell Anatomy 0.000 description 1
- 239000012138 yeast extract Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/56—Lactic acid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
- C12N1/16—Yeasts; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/62—Carboxylic acid esters
- C12P7/625—Polyesters of hydroxy carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/37—Assays involving biological materials from specific organisms or of a specific nature from fungi
- G01N2333/39—Assays involving biological materials from specific organisms or of a specific nature from fungi from yeasts
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Plant Pathology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Botany (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38433302P | 2002-05-30 | 2002-05-30 | |
| US384333P | 2002-05-30 | ||
| PCT/US2003/016825 WO2003102200A2 (en) | 2002-05-30 | 2003-05-30 | Fermentation process using specific oxygen uptake rates as a process control |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2529254T3 true ES2529254T3 (es) | 2015-02-18 |
Family
ID=29712012
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES03756237.8T Expired - Lifetime ES2529254T3 (es) | 2002-05-30 | 2003-05-30 | Proceso de fermentación usando velocidades de incorporación de oxígeno específicas como un control del proceso |
| ES14198669.5T Expired - Lifetime ES2642928T3 (es) | 2002-05-30 | 2003-05-30 | Proceso de fermentación usando velocidades de incorporación de oxígeno específicas como un control del proceso |
| ES03731489T Expired - Lifetime ES2290466T3 (es) | 2002-05-30 | 2003-05-30 | Metodos y materiales para la produccion de acido d-lactico en levadura. |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES14198669.5T Expired - Lifetime ES2642928T3 (es) | 2002-05-30 | 2003-05-30 | Proceso de fermentación usando velocidades de incorporación de oxígeno específicas como un control del proceso |
| ES03731489T Expired - Lifetime ES2290466T3 (es) | 2002-05-30 | 2003-05-30 | Metodos y materiales para la produccion de acido d-lactico en levadura. |
Country Status (15)
| Country | Link |
|---|---|
| US (7) | US7534597B2 (enExample) |
| EP (4) | EP1513923B1 (enExample) |
| JP (4) | JP4318638B2 (enExample) |
| CN (4) | CN1735691B (enExample) |
| AT (1) | ATE367436T1 (enExample) |
| AU (4) | AU2003240481B8 (enExample) |
| BR (4) | BR0311452A (enExample) |
| CA (3) | CA2488196A1 (enExample) |
| DE (1) | DE60315028T2 (enExample) |
| DK (1) | DK2878675T3 (enExample) |
| ES (3) | ES2529254T3 (enExample) |
| PT (1) | PT1513923E (enExample) |
| UA (2) | UA88437C2 (enExample) |
| WO (3) | WO2003102200A2 (enExample) |
| ZA (3) | ZA200409529B (enExample) |
Families Citing this family (120)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1294728B1 (it) | 1997-09-12 | 1999-04-12 | Biopolo S C A R L | Ceppi di lievito per la riproduzione di acido lattico |
| US20070031950A1 (en) * | 1998-09-11 | 2007-02-08 | Winkler Aaron A | Production of D-lactic acid with yeast |
| US7141410B2 (en) * | 2000-11-22 | 2006-11-28 | Natureworks Llc | Methods and materials for the production of organic products in cells of Candida species |
| WO2003102200A2 (en) | 2002-05-30 | 2003-12-11 | Cargill Dow Llc | Fermentation process using specific oxygen uptake rates as a process control |
| PL2345662T3 (pl) | 2003-05-02 | 2016-11-30 | Genetycznie modyfikowane gatunki drożdży i sposoby fermentacji z użyciem genetycznie modyfikowanych drożdży | |
| JP4460876B2 (ja) * | 2003-11-07 | 2010-05-12 | 株式会社豊田中央研究所 | 有機酸存在下におけるプロモーター及びその利用 |
| US20050112737A1 (en) * | 2003-11-20 | 2005-05-26 | A. E. Staley Manufacturing Co. | Lactic acid producing yeast |
| JP4806904B2 (ja) * | 2004-07-09 | 2011-11-02 | トヨタ自動車株式会社 | 乳酸生産方法 |
| JP2006296377A (ja) * | 2005-04-25 | 2006-11-02 | Toyota Central Res & Dev Lab Inc | 有機酸生産用形質転換体 |
| CN101287824A (zh) | 2005-06-02 | 2008-10-15 | 卡吉尔公司 | 东方伊氏酵母种及密切相关物种的基因修饰的酵母和采用它们的发酵方法 |
| DK1760156T3 (da) | 2005-08-10 | 2013-03-18 | Univ Florida | Materialer og fremgangsmåder til effektiv mælkesyrefremstilling |
| JP4692173B2 (ja) * | 2005-09-13 | 2011-06-01 | 東レ株式会社 | Ｄ−乳酸デヒドロゲナーゼ活性を有するポリペプチド、これをコードする遺伝子およびｄ−乳酸の製造方法 |
| US7718405B2 (en) * | 2005-09-19 | 2010-05-18 | American Air Liquide, Inc. | Use of pure oxygen in viscous fermentation processes |
| WO2007038130A2 (en) * | 2005-09-22 | 2007-04-05 | Tate & Lyle Ingredients Americas, Inc. | Improved strains for the production of organic acids |
| EP1975232A4 (en) * | 2005-10-14 | 2009-07-29 | Toray Industries | YEAST AND METHOD FOR THE PRODUCTION OF L-MILKY ACID |
| WO2007117282A2 (en) | 2005-11-23 | 2007-10-18 | Natureworks Llc | Lactic acid-producing yeast cells having nonfunctional l-or d-lactate: ferricytochrome c oxidoreductase gene |
| EP1989309B1 (en) * | 2006-01-24 | 2011-08-31 | PURAC Biochem BV | Genetic modification of homolactic thermophilic bacilli |
| EP2001992B1 (en) | 2006-03-13 | 2016-07-20 | Cargill Inc. | Yeast cells having disrupted pathway from dihydroxyacetone phosphate to glycerol |
| JP5320692B2 (ja) * | 2006-06-28 | 2013-10-23 | 東レ株式会社 | 酵母及びｌ−乳酸の製造方法 |
| US20080064076A1 (en) * | 2006-09-11 | 2008-03-13 | Saucedo Victor M | Dissolved Oxygen Profile to Increase Fermentation Productivity and Economics |
| JP5141126B2 (ja) * | 2006-09-26 | 2013-02-13 | 東レ株式会社 | 連続発酵によるｄ−乳酸の製造方法 |
| WO2008052596A1 (en) * | 2006-10-31 | 2008-05-08 | Metabolic Explorer | Process for the biological production of n-butanol with high yield |
| JP2010508013A (ja) * | 2006-10-31 | 2010-03-18 | メタボリック エクスプローラー | グリセロールから１，３−プロパンジオールを高収量で生物学的に製造する方法 |
| JP2010512147A (ja) | 2006-12-07 | 2010-04-22 | マサチューセッツ インスティテュート オブ テクノロジー | 包括的転写マシナリーエンジニアリング |
| JP5130826B2 (ja) * | 2007-03-28 | 2013-01-30 | 東レ株式会社 | 連続発酵による乳酸の製造方法 |
| JP2008283917A (ja) * | 2007-05-18 | 2008-11-27 | Toray Ind Inc | 乳酸の製造方法 |
| CN101868532A (zh) | 2007-09-20 | 2010-10-20 | 阿迈瑞斯生物技术公司 | 类异戊二烯的制备 |
| ES2616428T3 (es) * | 2007-12-07 | 2017-06-13 | Toray Industries, Inc. | Casete de expresión para lactasa deshidrogenasa, levadura transformada y método para producir ácido láctico |
| JP2011507532A (ja) * | 2007-12-23 | 2011-03-10 | ジーヴォ，インコーポレイテッド | 高収率でイソブタノールを産生する酵母生物 |
| US8455239B2 (en) * | 2007-12-23 | 2013-06-04 | Gevo, Inc. | Yeast organism producing isobutanol at a high yield |
| JP2011514140A (ja) | 2007-12-27 | 2011-05-06 | ジーヴォ，インコーポレイテッド | 低濃度水溶液からの高級アルコールの回収 |
| BRPI0905928A2 (pt) * | 2008-02-04 | 2015-08-04 | Toray Industries | "método de produção de ácido lático" |
| US20090235951A1 (en) * | 2008-03-18 | 2009-09-24 | Legrande W E | Environmentally Responsible Dental Floss and Packaging |
| JP4963488B2 (ja) * | 2008-04-23 | 2012-06-27 | トヨタ自動車株式会社 | 変異体酵母及びこれを用いた物質生産方法 |
| EA018463B1 (ru) | 2008-07-08 | 2013-08-30 | ДСМ АйПи АССЕТС Б.В. | ПОЛУЧЕНИЕ ДИКАРБОНОВЫХ КИСЛОТ ПРИ НИЗКИХ pH |
| ES2401155T3 (es) | 2008-10-03 | 2013-04-17 | Metabolic Explorer | Procedimiento para la purificación de un alcohol a partir de un caldo de fermentación que utiliza un evaporador de película descendente, de película renovada, de película fina o de recorrido corto |
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| KR20120104509A (ko) * | 2009-06-26 | 2012-09-21 | 게보 인코포레이티드 | 묽은 수용액으로부터 고급 알코올들의 회수 |
| SG176970A1 (en) | 2009-07-02 | 2012-02-28 | Verdezyne Inc | Biological methods for preparing adipic acid |
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| JP5913099B2 (ja) | 2009-07-30 | 2016-04-27 | メタボリック エクスプローラー | 発酵による生化学物質生産のための変異型メチルグリオキサールシンターゼ（ｍｇｓ） |
| EP2470667B1 (en) | 2009-08-27 | 2017-11-15 | DSM IP Assets B.V. | Dicarboxylic acid fermentation process |
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| EA201201449A1 (ru) | 2010-04-21 | 2013-03-29 | ДСМ АйПи АССЕТС Б.В. | Способ получения клеток, способных преобразовывать арабинозу |
| US9012190B2 (en) | 2011-06-15 | 2015-04-21 | Butamax Advanced Biofuels Llc | Use of thiamine and nicotine adenine dinucleotide for butanol production |
| US20130130339A1 (en) * | 2010-07-31 | 2013-05-23 | Myriant Corporation | Fermentation process for the production of organic acids |
| MY160995A (en) | 2010-10-13 | 2017-03-28 | Dsm Ip Assets Bv | Polypeptides with permease activity |
| MX2013005654A (es) | 2010-11-22 | 2013-07-17 | Novozymes Inc | Composiciones y metodos para la produccion de acido 3-hidroxipropionico. |
| CA2885934C (en) | 2010-11-22 | 2018-05-01 | Cargill, Incorporated | Compositions and methods for increased ethanol titer from biomass |
| US9605285B2 (en) | 2011-01-25 | 2017-03-28 | Cargill, Incorporated | Compositions and methods for succinate production |
| CN103649306B (zh) * | 2011-03-29 | 2015-07-01 | 雀巢产品技术援助有限公司 | 在d乳酸生产中有缺陷以及具有改善的免疫特征的约氏乳杆菌菌株cncm i-1225的天然衍生物 |
| EP3401322B1 (en) | 2011-04-07 | 2022-06-08 | Virdia, LLC | Lignocellulose conversion processes and products |
| EP2697252B1 (en) | 2011-04-11 | 2016-08-10 | Cargill, Incorporated | Compositions and methods for increased ethanol production from biomass |
| EA201301193A1 (ru) | 2011-04-22 | 2014-02-28 | ДСМ АйПи АССЕТС Б.В. | Дрожжевые клетки, способные к превращению сахаров, содержащих арабинозу и ксилозу |
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